| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | (R)-Verapamil (hydrochloride) perturbation in NCI-H1573 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the (R)-Verapamil (hydrochloride)_NCI-H1573 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | 0.23567 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.131147 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | 0.124434 |
| GRAMD1B | GRAM domain containing 1B | 0.101947 |
| MT2A | metallothionein 2A | 0.0999816 |
| SEMA3C | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C | 0.0877687 |
| ELL2 | elongation factor, RNA polymerase II, 2 | 0.0824938 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | 0.0817091 |
| DOCK5 | dedicator of cytokinesis 5 | 0.0696115 |
| PM20D1 | peptidase M20 domain containing 1 | 0.0691471 |
| SLTM | SAFB-like, transcription modulator | 0.0665553 |
| RPS3 | ribosomal protein S3 | 0.0662081 |
| IGFBP3 | insulin-like growth factor binding protein 3 | 0.0646165 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | 0.0612091 |
| SMYD3 | SET and MYND domain containing 3 | 0.053123 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | 0.0527286 |
| BCAR3 | breast cancer anti-estrogen resistance 3 | 0.0519344 |
| CEMIP | cell migration inducing protein, hyaluronan binding | 0.0517219 |
| AREG | amphiregulin | 0.0508013 |
| EXT1 | exostosin glycosyltransferase 1 | 0.0499263 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.0486934 |
| THSD4 | thrombospondin, type I, domain containing 4 | 0.0482496 |
| RPS12 | ribosomal protein S12 | 0.0476111 |
| MCL1 | myeloid cell leukemia 1 | 0.0459497 |
| NR4A3 | nuclear receptor subfamily 4, group A, member 3 | 0.0446544 |
| STC1 | stanniocalcin 1 | 0.0416628 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | 0.0396934 |
| FOXP1 | forkhead box P1 | 0.0387812 |
| JMJD1C | jumonji domain containing 1C | 0.0385609 |
| RNF213 | ring finger protein 213 | 0.0384503 |
| MYO1E | myosin IE | 0.0383553 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0366101 |
| DOCK1 | dedicator of cytokinesis 1 | 0.0360762 |
| SAMD4A | sterile alpha motif domain containing 4A | 0.0355033 |
| ENO1 | enolase 1, (alpha) | 0.0349026 |
| INTS6 | integrator complex subunit 6 | 0.0341068 |
| TRAPPC9 | trafficking protein particle complex 9 | 0.0340282 |
| MORF4L2 | mortality factor 4 like 2 | 0.0339017 |
| SIK3 | SIK family kinase 3 | 0.0331661 |
| NR3C1 | nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) | 0.032952 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.0328382 |
| EZR | ezrin | 0.0327225 |
| STAT3 | signal transducer and activator of transcription 3 (acute-phase response factor) | 0.0323847 |
| SEC61G | Sec61 gamma subunit | 0.0321987 |
| NPAS2 | neuronal PAS domain protein 2 | 0.0321158 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0317459 |
| RPS8 | ribosomal protein S8 | 0.0314399 |
| ATP1B3 | ATPase, Na+/K+ transporting, beta 3 polypeptide | 0.0311542 |
| CYP24A1 | cytochrome P450, family 24, subfamily A, polypeptide 1 | 0.0310456 |
| LMO7 | LIM domain 7 | 0.0305971 |
| NEDD4L | neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase | 0.02994 |
| BMP6 | bone morphogenetic protein 6 | 0.0298205 |
| LAMA4 | laminin, alpha 4 | 0.0292776 |
| MAP7 | microtubule-associated protein 7 | 0.0292769 |
| TBC1D22A | TBC1 domain family, member 22A | 0.0291276 |
| NDRG1 | N-myc downstream regulated 1 | 0.0289627 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | 0.0289255 |
| RPL37A | ribosomal protein L37a | 0.0285844 |
| RPS4X | ribosomal protein S4, X-linked | 0.0284714 |
| TPT1 | tumor protein, translationally-controlled 1 | 0.0282709 |
| SHANK2 | SH3 and multiple ankyrin repeat domains 2 | 0.0280279 |
| SPAG9 | sperm associated antigen 9 | 0.0277847 |
| FNDC3A | fibronectin type III domain containing 3A | 0.0273413 |
| RIMS2 | regulating synaptic membrane exocytosis 2 | 0.0272718 |
| TOP1 | topoisomerase (DNA) I | 0.0271684 |
| LGALS12 | lectin, galactoside-binding, soluble, 12 | 0.0265418 |
| RPL23 | ribosomal protein L23 | 0.026514 |
| MYOF | myoferlin | 0.02651 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.0264002 |
| NTN4 | netrin 4 | 0.0263019 |
| SYAP1 | synapse associated protein 1 | 0.0262663 |
| MAML3 | mastermind-like 3 (Drosophila) | 0.0262034 |
| FZR1 | fizzy/cell division cycle 20 related 1 (Drosophila) | 0.0261167 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | 0.0259381 |
| BPTF | bromodomain PHD finger transcription factor | 0.0259045 |
| DYNC1H1 | dynein, cytoplasmic 1, heavy chain 1 | 0.025815 |
| MBNL1 | muscleblind-like splicing regulator 1 | 0.0257531 |
| RPS17 | ribosomal protein S17 | 0.0255341 |
| ACTN1 | actinin, alpha 1 | 0.0253806 |
| DST | dystonin | 0.0249911 |
| DNAJC1 | DnaJ (Hsp40) homolog, subfamily C, member 1 | 0.0243194 |
| LDHA | lactate dehydrogenase A | 0.0235415 |
| FUS | FUS RNA binding protein | 0.0232786 |
| WSB1 | WD repeat and SOCS box containing 1 | 0.0232723 |
| ATP2B1 | ATPase, Ca++ transporting, plasma membrane 1 | 0.0232187 |
| S100P | S100 calcium binding protein P | 0.0230854 |
| RALGAPA2 | Ral GTPase activating protein, alpha subunit 2 (catalytic) | 0.0229152 |
| CCSER1 | coiled-coil serine-rich protein 1 | 0.0228712 |
| RAD51B | RAD51 paralog B | 0.0228069 |
| JUN | jun proto-oncogene | 0.0226065 |
| RACK1 | receptor for activated C kinase 1 | 0.0225689 |
| RPS29 | ribosomal protein S29 | 0.022438 |
| NTSR1 | neurotensin receptor 1 (high affinity) | 0.0224309 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | 0.0222129 |
| ATF6 | activating transcription factor 6 | 0.0217313 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.0216793 |
| HOMER1 | homer scaffolding protein 1 | 0.021678 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.021619 |
| TNFAIP8 | tumor necrosis factor, alpha-induced protein 8 | 0.0215612 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | 0.021458 |
| Symbol | Name | Standardized Value |
|---|---|---|
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.197313 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | -0.106517 |
| TMSB10 | thymosin beta 10 | -0.0891988 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.0747934 |
| CAV1 | caveolin 1, caveolae protein, 22kDa | -0.0695267 |
| PTGS2 | prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) | -0.0682768 |
| LRP1B | low density lipoprotein receptor-related protein 1B | -0.0592034 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0539128 |
| PTPRM | protein tyrosine phosphatase, receptor type, M | -0.0532665 |
| GSK3B | glycogen synthase kinase 3 beta | -0.0489575 |
| SOD2 | superoxide dismutase 2, mitochondrial | -0.046692 |
| TMEM165 | transmembrane protein 165 | -0.0466057 |
| KRT7 | keratin 7, type II | -0.0452372 |
| H1-0 | H1.0 linker histone | -0.0445154 |
| ACTG1 | actin gamma 1 | -0.0437192 |
| TXNRD1 | thioredoxin reductase 1 | -0.0435045 |
| EGFR | epidermal growth factor receptor | -0.0428685 |
| DDX17 | DEAD (Asp-Glu-Ala-Asp) box helicase 17 | -0.0428637 |
| POTEF | POTE ankyrin domain family, member F | -0.0386828 |
| CST3 | cystatin C | -0.0356145 |
| SMG1 | SMG1 phosphatidylinositol 3-kinase-related kinase | -0.0354894 |
| WASF2 | WAS protein family, member 2 | -0.0351167 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.0344212 |
| AKR1C1 | aldo-keto reductase family 1, member C1 | -0.0341631 |
| CAMTA1 | calmodulin binding transcription activator 1 | -0.0339352 |
| CES1 | carboxylesterase 1 | -0.0339303 |
| RICTOR | RPTOR independent companion of MTOR, complex 2 | -0.0334939 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.0310464 |
| PATJ | PATJ crumbs cell polarity complex component | -0.0303159 |
| ASPH | aspartate beta-hydroxylase | -0.0300296 |
| FHIP1A | FHF complex subunit HOOK interacting protein 1A | -0.0298633 |
| NGLY1 | N-glycanase 1 | -0.0282669 |
| HMGA1 | high mobility group AT-hook 1 | -0.0275079 |
| CCNL1 | cyclin L1 | -0.0274882 |
| LAMC2 | laminin, gamma 2 | -0.0269212 |
| KDM2A | lysine (K)-specific demethylase 2A | -0.0265051 |
| PERP | PERP, TP53 apoptosis effector | -0.0262706 |
| SLCO4A1 | solute carrier organic anion transporter family, member 4A1 | -0.0260526 |
| RAB27B | RAB27B, member RAS oncogene family | -0.0258579 |
| SREBF2 | sterol regulatory element binding transcription factor 2 | -0.0256513 |
| KRT8 | keratin 8, type II | -0.0255068 |
| BIRC3 | baculoviral IAP repeat containing 3 | -0.0255028 |
| MKI67 | marker of proliferation Ki-67 | -0.0245504 |
| BAZ2A | bromodomain adjacent to zinc finger domain, 2A | -0.0243922 |
| LANCL2 | LanC lantibiotic synthetase component C-like 2 (bacterial) | -0.0239962 |
| ADAM17 | ADAM metallopeptidase domain 17 | -0.0238355 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | -0.0236942 |
| MON2 | MON2 homolog (S. cerevisiae) | -0.0234863 |
| MARF1 | meiosis regulator and mRNA stability factor 1 | -0.0230939 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0226299 |
| ANKRD10 | ankyrin repeat domain 10 | -0.02255 |
| ARHGAP32 | Rho GTPase activating protein 32 | -0.0223686 |
| SBF2 | SET binding factor 2 | -0.0220341 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0219494 |
| KCMF1 | potassium channel modulatory factor 1 | -0.0217086 |
| SETD5 | SET domain containing 5 | -0.0215461 |
| NDE1 | nudE neurodevelopment protein 1 | -0.0214326 |
| TPD52 | tumor protein D52 | -0.0210862 |
| HDLBP | high density lipoprotein binding protein | -0.0210431 |
| FNIP1 | folliculin interacting protein 1 | -0.020898 |
| PTEN | phosphatase and tensin homolog | -0.0204513 |
| SLC38A1 | solute carrier family 38, member 1 | -0.0202128 |
| S100A6 | S100 calcium binding protein A6 | -0.0200956 |
| ADAM9 | ADAM metallopeptidase domain 9 | -0.0200563 |
| SRRM2 | serine/arginine repetitive matrix 2 | -0.0199583 |
| RAB1A | RAB1A, member RAS oncogene family | -0.0197972 |
| ANXA2 | annexin A2 | -0.0197346 |
| CLDN7 | claudin 7 | -0.0192176 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | -0.0187208 |
| PTMA | prothymosin, alpha | -0.0185888 |
| RAB7A | RAB7A, member RAS oncogene family | -0.0184023 |
| CAV2 | caveolin 2 | -0.0183885 |
| SDC4 | syndecan 4 | -0.0183799 |
| PFN1 | profilin 1 | -0.0183697 |
| TENT5A | terminal nucleotidyltransferase 5A | -0.0182046 |
| MAML2 | mastermind-like 2 (Drosophila) | -0.0181916 |
| SPIRE1 | spire-type actin nucleation factor 1 | -0.0181199 |
| SLC7A11 | solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 | -0.0181061 |
| TAPBP | TAP binding protein (tapasin) | -0.0179825 |
| KRT19 | keratin 19, type I | -0.0174804 |
| SLMAP | sarcolemma associated protein | -0.0174791 |
| ZNF148 | zinc finger protein 148 | -0.0173214 |
| ARHGEF12 | Rho guanine nucleotide exchange factor (GEF) 12 | -0.0172057 |
| NFKBIZ | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, zeta | -0.0171911 |
| NDUFV2 | NADH dehydrogenase (ubiquinone) flavoprotein 2, 24kDa | -0.0171878 |
| RIN2 | Ras and Rab interactor 2 | -0.017106 |
| ATG7 | autophagy related 7 | -0.0169323 |
| GORASP2 | golgi reassembly stacking protein 2, 55kDa | -0.0169121 |
| HCFC1 | host cell factor C1 | -0.0167773 |
| PPP1R15B | protein phosphatase 1, regulatory subunit 15B | -0.0166429 |
| ASH1L | ash1 (absent, small, or homeotic)-like (Drosophila) | -0.0163195 |
| RAP1B | RAP1B, member of RAS oncogene family | -0.016106 |
| KDM5B | lysine (K)-specific demethylase 5B | -0.0160499 |
| CTTN | cortactin | -0.0160461 |
| CPEB2 | cytoplasmic polyadenylation element binding protein 2 | -0.015967 |
| BIRC6 | baculoviral IAP repeat containing 6 | -0.0158325 |
| NUFIP2 | nuclear fragile X mental retardation protein interacting protein 2 | -0.0157148 |
| RPL35A | ribosomal protein L35a | -0.0156499 |
| MDM2 | MDM2 proto-oncogene, E3 ubiquitin protein ligase | -0.0155908 |
| MSN | moesin | -0.0155756 |
