| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | (R)-Verapamil (hydrochloride) perturbation in NCI-H2030 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the (R)-Verapamil (hydrochloride)_NCI-H2030 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| MT2A | metallothionein 2A | 0.257959 |
| IGFBP3 | insulin-like growth factor binding protein 3 | 0.115073 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | 0.0809697 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.0800358 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | 0.0639593 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.0638996 |
| RPL23 | ribosomal protein L23 | 0.0528879 |
| PM20D1 | peptidase M20 domain containing 1 | 0.0503232 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0472003 |
| CCL5 | chemokine (C-C motif) ligand 5 | 0.040645 |
| FLNB | filamin B, beta | 0.0381565 |
| RPS8 | ribosomal protein S8 | 0.0378957 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0364545 |
| C15ORF48 | chromosome 15 open reading frame 48 | 0.0361511 |
| SAMD4A | sterile alpha motif domain containing 4A | 0.0344408 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.0333545 |
| ACTN1 | actinin, alpha 1 | 0.0333309 |
| RPS12 | ribosomal protein S12 | 0.0333235 |
| HLA-B | major histocompatibility complex, class I, B | 0.0327292 |
| NDRG1 | N-myc downstream regulated 1 | 0.0326511 |
| PHLDB2 | pleckstrin homology-like domain, family B, member 2 | 0.0317526 |
| DOCK5 | dedicator of cytokinesis 5 | 0.0317479 |
| HMOX1 | heme oxygenase 1 | 0.0313599 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0300207 |
| HSPA8 | heat shock 70kDa protein 8 | 0.029818 |
| MORF4L2 | mortality factor 4 like 2 | 0.0290223 |
| ANGPTL4 | angiopoietin-like 4 | 0.0281226 |
| STAT3 | signal transducer and activator of transcription 3 (acute-phase response factor) | 0.02744 |
| RPLP1 | ribosomal protein, large, P1 | 0.0272523 |
| RPL37A | ribosomal protein L37a | 0.0268447 |
| RPS17 | ribosomal protein S17 | 0.0263255 |
| BMP6 | bone morphogenetic protein 6 | 0.025918 |
| BASP1 | brain abundant, membrane attached signal protein 1 | 0.0255647 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | 0.0253426 |
| RPS3 | ribosomal protein S3 | 0.0251964 |
| ARHGAP26 | Rho GTPase activating protein 26 | 0.0250693 |
| TIMP1 | TIMP metallopeptidase inhibitor 1 | 0.0240553 |
| RPL36 | ribosomal protein L36 | 0.0239973 |
| CYP24A1 | cytochrome P450, family 24, subfamily A, polypeptide 1 | 0.0239424 |
| RPS27 | ribosomal protein S27 | 0.0237964 |
| GRAMD1B | GRAM domain containing 1B | 0.0230865 |
| ELL2 | elongation factor, RNA polymerase II, 2 | 0.0229369 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | 0.022624 |
| ZNRF1 | zinc and ring finger 1, E3 ubiquitin protein ligase | 0.0223789 |
| RPS29 | ribosomal protein S29 | 0.0223385 |
| CFLAR | CASP8 and FADD-like apoptosis regulator | 0.0223044 |
| PRRC2C | proline-rich coiled-coil 2C | 0.0221396 |
| LAMC2 | laminin, gamma 2 | 0.0218576 |
| WWOX | WW domain containing oxidoreductase | 0.0217358 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | 0.0216585 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | 0.021156 |
| ATXN1 | ataxin 1 | 0.0211406 |
| MCL1 | myeloid cell leukemia 1 | 0.0211276 |
| RPL31 | ribosomal protein L31 | 0.0211135 |
| TAF15 | TAF15 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 68kDa | 0.0210219 |
| SOD2 | superoxide dismutase 2, mitochondrial | 0.0207605 |
| RPS4X | ribosomal protein S4, X-linked | 0.0207598 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0206551 |
| IER3 | immediate early response 3 | 0.0204292 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.0203242 |
| GOLGB1 | golgin B1 | 0.0201241 |
| DLGAP4 | discs, large (Drosophila) homolog-associated protein 4 | 0.019965 |
| SMOC1 | SPARC related modular calcium binding 1 | 0.0199105 |
| PTPRJ | protein tyrosine phosphatase, receptor type, J | 0.019308 |
| KIAA0319 | KIAA0319 | 0.0192133 |
| APP | amyloid beta (A4) precursor protein | 0.0190566 |
| TM4SF1 | transmembrane 4 L six family member 1 | 0.0189416 |
| ABTB2 | ankyrin repeat and BTB (POZ) domain containing 2 | 0.018603 |
| INHBA | inhibin, beta A | 0.0182628 |
| IRAK2 | interleukin-1 receptor-associated kinase 2 | 0.0178829 |
| S100A10 | S100 calcium binding protein A10 | 0.0177367 |
| PRELID2 | PRELI domain containing 2 | 0.0176551 |
| NPAS2 | neuronal PAS domain protein 2 | 0.017612 |
| EPAS1 | endothelial PAS domain protein 1 | 0.0174229 |
| SFTPA2 | surfactant protein A2 | 0.0170991 |
| GALNT2 | polypeptide N-acetylgalactosaminyltransferase 2 | 0.0169223 |
| NUMB | numb homolog (Drosophila) | 0.0168209 |
| HLA-E | major histocompatibility complex, class I, E | 0.0164601 |
| SEPTIN9 | septin 9 | 0.0164261 |
| PLEC | plectin | 0.0162902 |
| SRP14 | signal recognition particle 14kDa (homologous Alu RNA binding protein) | 0.0162116 |
| NIPBL | Nipped-B homolog (Drosophila) | 0.0161616 |
| FUS | FUS RNA binding protein | 0.016028 |
| DYNC1H1 | dynein, cytoplasmic 1, heavy chain 1 | 0.016022 |
| TNFAIP8 | tumor necrosis factor, alpha-induced protein 8 | 0.0158953 |
| UBAP2L | ubiquitin associated protein 2-like | 0.0158575 |
| PHF21A | PHD finger protein 21A | 0.015793 |
| SERINC1 | serine incorporator 1 | 0.0156455 |
| TANC2 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 | 0.0154984 |
| ARID1B | AT rich interactive domain 1B (SWI1-like) | 0.0154863 |
| RPL17-C18ORF32 | RPL17-C18orf32 readthrough | 0.0154074 |
| NFE2L2 | nuclear factor, erythroid 2-like 2 | 0.0153334 |
| TERF2IP | telomeric repeat binding factor 2, interacting protein | 0.0151092 |
| BTBD9 | BTB (POZ) domain containing 9 | 0.015024 |
| IL6 | interleukin 6 | 0.0148049 |
| EZR | ezrin | 0.0147995 |
| DSPP | dentin sialophosphoprotein | 0.0146124 |
| RPL18 | ribosomal protein L18 | 0.0145313 |
| KIF13A | kinesin family member 13A | 0.0145005 |
| LAMC1 | laminin, gamma 1 (formerly LAMB2) | 0.0144562 |
| Symbol | Name | Standardized Value |
|---|---|---|
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.238916 |
| VIM | vimentin | -0.141119 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.13579 |
| TXNRD1 | thioredoxin reductase 1 | -0.123398 |
| ROBO2 | roundabout, axon guidance receptor, homolog 2 (Drosophila) | -0.117233 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.104553 |
| ACTG1 | actin gamma 1 | -0.0820561 |
| TFPI2 | tissue factor pathway inhibitor 2 | -0.0772097 |
| TMSB10 | thymosin beta 10 | -0.0769493 |
| IGF2 | insulin-like growth factor 2 | -0.0727919 |
| RPS4Y1 | ribosomal protein S4, Y-linked 1 | -0.0689665 |
| WDR43 | WD repeat domain 43 | -0.0689576 |
| HDAC9 | histone deacetylase 9 | -0.06545 |
| POTEF | POTE ankyrin domain family, member F | -0.0652687 |
| FGB | fibrinogen beta chain | -0.0642161 |
| MKLN1 | muskelin 1, intracellular mediator containing kelch motifs | -0.0571351 |
| RTN4 | reticulon 4 | -0.0557479 |
| TPM4 | tropomyosin 4 | -0.0551669 |
| ERBIN | erbb2 interacting protein | -0.0551032 |
| EGR1 | early growth response 1 | -0.0542874 |
| PTK2 | protein tyrosine kinase 2 | -0.0524399 |
| PFN1 | profilin 1 | -0.0519107 |
| AP2B1 | adaptor-related protein complex 2, beta 1 subunit | -0.0518406 |
| NQO1 | NAD(P)H dehydrogenase, quinone 1 | -0.0496431 |
| S100A6 | S100 calcium binding protein A6 | -0.0490218 |
| ATP5F1B | ATP synthase F1 subunit beta | -0.0481306 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0474456 |
| SRGAP1 | SLIT-ROBO Rho GTPase activating protein 1 | -0.046686 |
| PKM | pyruvate kinase, muscle | -0.0464835 |
| SLC38A2 | solute carrier family 38, member 2 | -0.0463257 |
| ZNF207 | zinc finger protein 207 | -0.0444478 |
| THSD4 | thrombospondin, type I, domain containing 4 | -0.0430557 |
| RHOA | ras homolog family member A | -0.0426777 |
| RASAL2 | RAS protein activator like 2 | -0.0426748 |
| FTL | ferritin, light polypeptide | -0.0425579 |
| CITED2 | Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2 | -0.041499 |
| AK1 | adenylate kinase 1 | -0.0409824 |
| SEMA3A | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A | -0.0403521 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0403281 |
| ASH1L | ash1 (absent, small, or homeotic)-like (Drosophila) | -0.0393072 |
| XRCC5 | X-ray repair complementing defective repair in Chinese hamster cells 5 (double-strand-break rejoining) | -0.0379808 |
| HNRNPC | heterogeneous nuclear ribonucleoprotein C (C1/C2) | -0.0378404 |
| CYP1B1 | cytochrome P450, family 1, subfamily B, polypeptide 1 | -0.0377128 |
| PTMA | prothymosin, alpha | -0.0361872 |
| PAWR | PRKC, apoptosis, WT1, regulator | -0.03586 |
| LDHA | lactate dehydrogenase A | -0.035416 |
| CYRIB | CYFIP related Rac1 interactor B | -0.035339 |
| CHN1 | chimerin 1 | -0.0350978 |
| USP3 | ubiquitin specific peptidase 3 | -0.0349365 |
| UTRN | utrophin | -0.0343692 |
| RBM25 | RNA binding motif protein 25 | -0.0340367 |
| BABAM2 | BRISC and BRCA1 A complex member 2 | -0.0339868 |
| RHEB | Ras homolog enriched in brain | -0.0339328 |
| HMGA1 | high mobility group AT-hook 1 | -0.0338964 |
| SLC7A11 | solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 | -0.0338711 |
| RERE | arginine-glutamic acid dipeptide (RE) repeats | -0.0337172 |
| RAD21 | RAD21 homolog (S. pombe) | -0.0334796 |
| RBM39 | RNA binding motif protein 39 | -0.0334198 |
| KCNQ5 | potassium channel, voltage gated KQT-like subfamily Q, member 5 | -0.0328583 |
| DENND4A | DENN/MADD domain containing 4A | -0.0328553 |
| IGFBP4 | insulin-like growth factor binding protein 4 | -0.0323978 |
| CCNL1 | cyclin L1 | -0.0323569 |
| TAGLN2 | transgelin 2 | -0.0323112 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0320847 |
| TBL1XR1 | transducin (beta)-like 1 X-linked receptor 1 | -0.0319599 |
| KHDC4 | KH domain containing 4, pre-mRNA splicing factor | -0.0318158 |
| PPP3CA | protein phosphatase 3, catalytic subunit, alpha isozyme | -0.0314693 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | -0.0311434 |
| TPM3 | tropomyosin 3 | -0.0311069 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | -0.031086 |
| SEMA3C | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C | -0.030664 |
| PDLIM5 | PDZ and LIM domain 5 | -0.0300168 |
| MTHFD1L | methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1-like | -0.0289334 |
| PSMD14 | proteasome (prosome, macropain) 26S subunit, non-ATPase, 14 | -0.0286869 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.0284883 |
| LRPPRC | leucine-rich pentatricopeptide repeat containing | -0.0284103 |
| BICC1 | BicC family RNA binding protein 1 | -0.0283611 |
| ACACA | acetyl-CoA carboxylase alpha | -0.0277886 |
| THBS1 | thrombospondin 1 | -0.0277299 |
| NEGR1 | neuronal growth regulator 1 | -0.0273772 |
| NOL10 | nucleolar protein 10 | -0.026846 |
| SYNE2 | spectrin repeat containing, nuclear envelope 2 | -0.026763 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | -0.0267507 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0266404 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.0264968 |
| ZFAND3 | zinc finger, AN1-type domain 3 | -0.0264847 |
| ECT2 | epithelial cell transforming 2 | -0.026466 |
| CMIP | c-Maf inducing protein | -0.0260351 |
| EFNA5 | ephrin-A5 | -0.0257184 |
| RPLP0 | ribosomal protein, large, P0 | -0.0256316 |
| MAP1LC3B | microtubule-associated protein 1 light chain 3 beta | -0.0255399 |
| GNAS | GNAS complex locus | -0.0251139 |
| ADGRG6 | adhesion G protein-coupled receptor G6 | -0.0247278 |
| CNOT1 | CCR4-NOT transcription complex, subunit 1 | -0.0245411 |
| ADAM9 | ADAM metallopeptidase domain 9 | -0.024333 |
| BCLAF1 | BCL2-associated transcription factor 1 | -0.0242445 |
| KPNB1 | karyopherin (importin) beta 1 | -0.0238228 |
| CBX5 | chromobox homolog 5 | -0.0238118 |
| CENPF | centromere protein F, 350/400kDa | -0.0238106 |
| IST1 | increased sodium tolerance 1 homolog (yeast) | -0.0237481 |
