| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | (R)-Verapamil (hydrochloride) perturbation in NCI-H2122 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the (R)-Verapamil (hydrochloride)_NCI-H2122 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| PDE4D | phosphodiesterase 4D, cAMP-specific | 0.200415 |
| MYO1E | myosin IE | 0.13848 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | 0.103889 |
| MMAB | methylmalonic aciduria (cobalamin deficiency) cblB type | 0.0698447 |
| SAMD4A | sterile alpha motif domain containing 4A | 0.0665466 |
| FNDC3A | fibronectin type III domain containing 3A | 0.061086 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0585277 |
| NEDD4L | neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase | 0.0582867 |
| ELL2 | elongation factor, RNA polymerase II, 2 | 0.0581292 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0519658 |
| FZR1 | fizzy/cell division cycle 20 related 1 (Drosophila) | 0.0510035 |
| MAST4 | microtubule associated serine/threonine kinase family member 4 | 0.0506936 |
| HS6ST3 | heparan sulfate 6-O-sulfotransferase 3 | 0.0465862 |
| ELOF1 | elongation factor 1 homolog (S. cerevisiae) | 0.0464806 |
| FN1 | fibronectin 1 | 0.0460487 |
| ACTN4 | actinin, alpha 4 | 0.0436733 |
| PRELID2 | PRELI domain containing 2 | 0.0432797 |
| MCL1 | myeloid cell leukemia 1 | 0.0423784 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | 0.0423009 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | 0.0422541 |
| KDM2A | lysine (K)-specific demethylase 2A | 0.0415118 |
| PPARD | peroxisome proliferator-activated receptor delta | 0.0409944 |
| ANXA1 | annexin A1 | 0.0398023 |
| HIVEP3 | human immunodeficiency virus type I enhancer binding protein 3 | 0.0397174 |
| ADARB1 | adenosine deaminase, RNA-specific, B1 | 0.0387567 |
| NDRG1 | N-myc downstream regulated 1 | 0.038531 |
| PM20D1 | peptidase M20 domain containing 1 | 0.0381958 |
| VCL | vinculin | 0.037668 |
| DUSP10 | dual specificity phosphatase 10 | 0.0376065 |
| STEAP4 | STEAP family member 4 | 0.0369948 |
| N4BP2L2 | NEDD4 binding protein 2-like 2 | 0.0368991 |
| NABP1 | nucleic acid binding protein 1 | 0.0368099 |
| ERC2 | ELKS/RAB6-interacting/CAST family member 2 | 0.036322 |
| MAGI2 | membrane associated guanylate kinase, WW and PDZ domain containing 2 | 0.0355461 |
| ITGA3 | integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor) | 0.0353803 |
| CATSPERB | catsper channel auxiliary subunit beta | 0.0352191 |
| PTPRM | protein tyrosine phosphatase, receptor type, M | 0.0349862 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | 0.034892 |
| ATXN1 | ataxin 1 | 0.0348162 |
| NPAS2 | neuronal PAS domain protein 2 | 0.0342024 |
| TRAPPC9 | trafficking protein particle complex 9 | 0.0339036 |
| RAB11FIP1 | RAB11 family interacting protein 1 (class I) | 0.0338879 |
| NECTIN4 | nectin cell adhesion molecule 4 | 0.0337005 |
| PRKCSH | protein kinase C substrate 80K-H | 0.0327643 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | 0.0327285 |
| KRT17 | keratin 17, type I | 0.032718 |
| SPDYA | speedy/RINGO cell cycle regulator family member A | 0.0326007 |
| ROBO2 | roundabout, axon guidance receptor, homolog 2 (Drosophila) | 0.0324261 |
| CDK12 | cyclin-dependent kinase 12 | 0.0323801 |
| MYO1D | myosin ID | 0.0320667 |
| NBEAL1 | neurobeachin-like 1 | 0.031995 |
| GTF2IRD1 | GTF2I repeat domain containing 1 | 0.0317857 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | 0.0310999 |
| EXT1 | exostosin glycosyltransferase 1 | 0.0309918 |
| ARID5B | AT rich interactive domain 5B (MRF1-like) | 0.0308867 |
| BRAF | B-Raf proto-oncogene, serine/threonine kinase | 0.0307636 |
| STXBP5L | syntaxin binding protein 5-like | 0.0305501 |
| DNAJB6 | DnaJ (Hsp40) homolog, subfamily B, member 6 | 0.0300471 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | 0.0298491 |
| BCAS3 | breast carcinoma amplified sequence 3 | 0.0293293 |
| NCEH1 | neutral cholesterol ester hydrolase 1 | 0.0293032 |
| ITGB4 | integrin, beta 4 | 0.0291366 |
| OXSR1 | oxidative stress responsive 1 | 0.0289458 |
| LDLR | low density lipoprotein receptor | 0.0288684 |
| OPTN | optineurin | 0.0286959 |
| BRIP1 | BRCA1 interacting protein C-terminal helicase 1 | 0.0286911 |
| DIP2B | DIP2 disco-interacting protein 2 homolog B (Drosophila) | 0.0285113 |
| CEMIP2 | cell migration inducing hyaluronidase 2 | 0.0283313 |
| ATP9A | ATPase, class II, type 9A | 0.0281337 |
| NAV1 | neuron navigator 1 | 0.0280915 |
| KDM7A | lysine (K)-specific demethylase 7A | 0.0279319 |
| CDH13 | cadherin 13 | 0.0278641 |
| ITPRID2 | ITPR interacting domain containing 2 | 0.0275777 |
| SCAF11 | SR-related CTD-associated factor 11 | 0.0273494 |
| CHST15 | carbohydrate (N-acetylgalactosamine 4-sulfate 6-O) sulfotransferase 15 | 0.0273304 |
| SPOCK1 | sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 1 | 0.0270913 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | 0.0270331 |
| DENND2C | DENN/MADD domain containing 2C | 0.0267674 |
| SOX4 | SRY (sex determining region Y)-box 4 | 0.0267108 |
| ATP11B | ATPase, class VI, type 11B | 0.0266426 |
| PALM2AKAP2 | PALM2 and AKAP2 fusion | 0.0266069 |
| HECTD4 | HECT domain containing E3 ubiquitin protein ligase 4 | 0.0264879 |
| TAX1BP1 | Tax1 (human T-cell leukemia virus type I) binding protein 1 | 0.0263206 |
| PPP4R3B | protein phosphatase 4 regulatory subunit 3B | 0.0263057 |
| DUSP4 | dual specificity phosphatase 4 | 0.0262742 |
| CEP95 | centrosomal protein 95kDa | 0.0262435 |
| USP53 | ubiquitin specific peptidase 53 | 0.0262359 |
| RC3H1 | ring finger and CCCH-type domains 1 | 0.0261995 |
| HDAC8 | histone deacetylase 8 | 0.0259098 |
| ACTR3 | ARP3 actin-related protein 3 homolog (yeast) | 0.0258852 |
| BMAL2 | basic helix-loop-helix ARNT like 2 | 0.0258143 |
| ELF3 | E74-like factor 3 (ets domain transcription factor, epithelial-specific ) | 0.0255116 |
| DCAF6 | DDB1 and CUL4 associated factor 6 | 0.0251635 |
| OSBPL10 | oxysterol binding protein-like 10 | 0.0249125 |
| PDLIM5 | PDZ and LIM domain 5 | 0.0245913 |
| AP1G1 | adaptor-related protein complex 1, gamma 1 subunit | 0.024198 |
| AVL9 | AVL9 homolog (S. cerevisiase) | 0.0240793 |
| VMP1 | vacuole membrane protein 1 | 0.0239368 |
| PRDM1 | PR domain containing 1, with ZNF domain | 0.0237954 |
| NKD1 | naked cuticle homolog 1 (Drosophila) | 0.0237813 |
| Symbol | Name | Standardized Value |
|---|---|---|
| VIM | vimentin | -0.138881 |
| FTL | ferritin, light polypeptide | -0.129958 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.1295 |
| PTMA | prothymosin, alpha | -0.0943887 |
| NF1 | neurofibromin 1 | -0.0837121 |
| TMSB10 | thymosin beta 10 | -0.0812699 |
| MT2A | metallothionein 2A | -0.0764505 |
| JMJD1C | jumonji domain containing 1C | -0.0733372 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | -0.073196 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0731804 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0708637 |
| FNDC3B | fibronectin type III domain containing 3B | -0.0695852 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0592081 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | -0.0578163 |
| LMO7 | LIM domain 7 | -0.0576501 |
| RPL11 | ribosomal protein L11 | -0.0531569 |
| TXNRD1 | thioredoxin reductase 1 | -0.0528996 |
| ACTG1 | actin gamma 1 | -0.0524555 |
| IGF2BP2 | insulin-like growth factor 2 mRNA binding protein 2 | -0.0511381 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0502275 |
| RPL35A | ribosomal protein L35a | -0.0482807 |
| SPAG9 | sperm associated antigen 9 | -0.0451939 |
| LOXL2 | lysyl oxidase-like 2 | -0.0451422 |
| RPLP1 | ribosomal protein, large, P1 | -0.0448351 |
| RPS6 | ribosomal protein S6 | -0.0439834 |
| SRP54 | signal recognition particle 54kDa | -0.043677 |
| PARD3 | par-3 family cell polarity regulator | -0.0436141 |
| CANX | calnexin | -0.0434223 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0424773 |
| ZNF638 | zinc finger protein 638 | -0.0414119 |
| GRB10 | growth factor receptor-bound protein 10 | -0.0409329 |
| ZFC3H1 | zinc finger, C3H1-type containing | -0.0405047 |
| RPS16 | ribosomal protein S16 | -0.0404478 |
| NR3C1 | nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) | -0.0404206 |
| MAML3 | mastermind-like 3 (Drosophila) | -0.0401046 |
| USP3 | ubiquitin specific peptidase 3 | -0.0398343 |
| ATOSA | atos homolog A | -0.0388169 |
| B2M | beta-2-microglobulin | -0.0385783 |
| ELF2 | E74-like factor 2 (ets domain transcription factor) | -0.0370907 |
| FBF1 | Fas (TNFRSF6) binding factor 1 | -0.0370889 |
| FNIP1 | folliculin interacting protein 1 | -0.0368815 |
| UBE2H | ubiquitin-conjugating enzyme E2H | -0.0365519 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | -0.0364908 |
| KATNBL1 | katanin p80 subunit B-like 1 | -0.0364884 |
| PRKCA | protein kinase C, alpha | -0.0355642 |
| OGA | O-GlcNAcase | -0.0351884 |
| DLG1 | discs, large homolog 1 (Drosophila) | -0.0345645 |
| RIGI | RNA sensor RIG-I | -0.0332742 |
| ITCH | itchy E3 ubiquitin protein ligase | -0.0327867 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | -0.0324701 |
| AK1 | adenylate kinase 1 | -0.031676 |
| RPL19 | ribosomal protein L19 | -0.0314167 |
| KPNB1 | karyopherin (importin) beta 1 | -0.0310977 |
| SQSTM1 | sequestosome 1 | -0.0310577 |
| ANKIB1 | ankyrin repeat and IBR domain containing 1 | -0.0306292 |
| RPL37A | ribosomal protein L37a | -0.0300506 |
| ZEB1 | zinc finger E-box binding homeobox 1 | -0.0298757 |
| ZNF207 | zinc finger protein 207 | -0.029763 |
| ASH1L | ash1 (absent, small, or homeotic)-like (Drosophila) | -0.0296043 |
| ESYT2 | extended synaptotagmin-like protein 2 | -0.029472 |
| KANSL1 | KAT8 regulatory NSL complex subunit 1 | -0.0286923 |
| RPS14 | ribosomal protein S14 | -0.0285161 |
| RAB1A | RAB1A, member RAS oncogene family | -0.0277599 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0273609 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.0272957 |
| DDX17 | DEAD (Asp-Glu-Ala-Asp) box helicase 17 | -0.0270345 |
| RPS19 | ribosomal protein S19 | -0.0269779 |
| ENO1 | enolase 1, (alpha) | -0.0268672 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | -0.0268263 |
| SERPINA1 | serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1 | -0.0264261 |
| SLC25A36 | solute carrier family 25 (pyrimidine nucleotide carrier), member 36 | -0.0263954 |
| VDAC1 | voltage-dependent anion channel 1 | -0.0263697 |
| ASPH | aspartate beta-hydroxylase | -0.0263051 |
| BTAF1 | BTAF1 RNA polymerase II, B-TFIID transcription factor-associated, 170kDa | -0.0262218 |
| BRWD1 | bromodomain and WD repeat domain containing 1 | -0.0260776 |
| PAFAH1B1 | platelet-activating factor acetylhydrolase 1b, regulatory subunit 1 (45kDa) | -0.0258789 |
| NCOA2 | nuclear receptor coactivator 2 | -0.0258682 |
| SLC12A6 | solute carrier family 12 (potassium/chloride transporter), member 6 | -0.0257764 |
| RPS21 | ribosomal protein S21 | -0.025704 |
| RPLP2 | ribosomal protein, large, P2 | -0.0254567 |
| FGD6 | FYVE, RhoGEF and PH domain containing 6 | -0.025433 |
| CD63 | CD63 molecule | -0.0252832 |
| FMNL2 | formin-like 2 | -0.0251708 |
| UBR2 | ubiquitin protein ligase E3 component n-recognin 2 | -0.025046 |
| SLC38A1 | solute carrier family 38, member 1 | -0.0249672 |
| KHDC4 | KH domain containing 4, pre-mRNA splicing factor | -0.0248986 |
| APBB2 | amyloid beta (A4) precursor protein-binding, family B, member 2 | -0.024831 |
| CLMP | CXADR-like membrane protein | -0.0247886 |
| MAP3K20 | mitogen-activated protein kinase kinase kinase 20 | -0.0247035 |
| CHD1 | chromodomain helicase DNA binding protein 1 | -0.0246253 |
| TRIP12 | thyroid hormone receptor interactor 12 | -0.0244751 |
| SETD5 | SET domain containing 5 | -0.0244624 |
| APP | amyloid beta (A4) precursor protein | -0.0244597 |
| RNF145 | ring finger protein 145 | -0.024373 |
| NCOA1 | nuclear receptor coactivator 1 | -0.0243121 |
| KTN1 | kinectin 1 (kinesin receptor) | -0.0242367 |
| PMAIP1 | phorbol-12-myristate-13-acetate-induced protein 1 | -0.0241535 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | -0.0241471 |
| GOLGA4 | golgin A4 | -0.0238906 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0237654 |
