| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | (R)-Verapamil (hydrochloride) perturbation in NCI-H2347 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the (R)-Verapamil (hydrochloride)_NCI-H2347 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| NDRG1 | N-myc downstream regulated 1 | 0.154471 |
| FTL | ferritin, light polypeptide | 0.124752 |
| IGFBP3 | insulin-like growth factor binding protein 3 | 0.115128 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.0925945 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0918983 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0836992 |
| LAMB3 | laminin, beta 3 | 0.0832021 |
| CTNNB1 | catenin (cadherin-associated protein), beta 1, 88kDa | 0.0796872 |
| DUSP10 | dual specificity phosphatase 10 | 0.0669416 |
| WSB1 | WD repeat and SOCS box containing 1 | 0.0622387 |
| DSPP | dentin sialophosphoprotein | 0.061754 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0587854 |
| RPL23 | ribosomal protein L23 | 0.05709 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | 0.0559043 |
| EZR | ezrin | 0.0559011 |
| ELL2 | elongation factor, RNA polymerase II, 2 | 0.0542467 |
| PLEC | plectin | 0.0518296 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | 0.0517953 |
| PRRC2C | proline-rich coiled-coil 2C | 0.0509881 |
| APP | amyloid beta (A4) precursor protein | 0.0504856 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | 0.049706 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.047224 |
| RPS4X | ribosomal protein S4, X-linked | 0.0461933 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | 0.0458129 |
| SOX4 | SRY (sex determining region Y)-box 4 | 0.0458005 |
| SMURF1 | SMAD specific E3 ubiquitin protein ligase 1 | 0.0457419 |
| BCL2L1 | BCL2-like 1 | 0.0446438 |
| FLNB | filamin B, beta | 0.0445585 |
| NEDD4L | neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase | 0.0434674 |
| KLF6 | Kruppel-like factor 6 | 0.0412058 |
| SEMA3B | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3B | 0.0411821 |
| VGLL3 | vestigial-like family member 3 | 0.0411353 |
| YWHAG | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma | 0.0410071 |
| RACK1 | receptor for activated C kinase 1 | 0.0408612 |
| DST | dystonin | 0.0405864 |
| ENO1 | enolase 1, (alpha) | 0.0403216 |
| RPLP1 | ribosomal protein, large, P1 | 0.0399134 |
| LMO7 | LIM domain 7 | 0.0384387 |
| ABTB2 | ankyrin repeat and BTB (POZ) domain containing 2 | 0.0382867 |
| NR3C2 | nuclear receptor subfamily 3, group C, member 2 | 0.0382097 |
| B4GALT5 | UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 5 | 0.0378862 |
| MYO5B | myosin VB | 0.0376603 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0376513 |
| NR3C1 | nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) | 0.0372694 |
| EIF3A | eukaryotic translation initiation factor 3, subunit A | 0.0370093 |
| NRIP1 | nuclear receptor interacting protein 1 | 0.0366115 |
| UPP1 | uridine phosphorylase 1 | 0.0361065 |
| BHLHE40 | basic helix-loop-helix family, member e40 | 0.0358265 |
| EPS8 | epidermal growth factor receptor pathway substrate 8 | 0.0357258 |
| SPSB1 | splA/ryanodine receptor domain and SOCS box containing 1 | 0.034966 |
| TM4SF1 | transmembrane 4 L six family member 1 | 0.0340541 |
| ARRDC3 | arrestin domain containing 3 | 0.0339506 |
| STAT3 | signal transducer and activator of transcription 3 (acute-phase response factor) | 0.0338911 |
| EGFR | epidermal growth factor receptor | 0.033695 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.0328252 |
| FBXO32 | F-box protein 32 | 0.0326012 |
| UBAP2L | ubiquitin associated protein 2-like | 0.0322265 |
| RPS29 | ribosomal protein S29 | 0.0321809 |
| BASP1 | brain abundant, membrane attached signal protein 1 | 0.0321162 |
| FUS | FUS RNA binding protein | 0.0314896 |
| TXNIP | thioredoxin interacting protein | 0.0314507 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0312581 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | 0.0311676 |
| JUN | jun proto-oncogene | 0.0311247 |
| MORF4L2 | mortality factor 4 like 2 | 0.0308813 |
| MT2A | metallothionein 2A | 0.0305921 |
| EIF1 | eukaryotic translation initiation factor 1 | 0.030411 |
| FNBP1L | formin binding protein 1-like | 0.0303053 |
| MKI67 | marker of proliferation Ki-67 | 0.0300287 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | 0.0298633 |
| AHNAK2 | AHNAK nucleoprotein 2 | 0.0292085 |
| TUFT1 | tuftelin 1 | 0.0291616 |
| RPS19 | ribosomal protein S19 | 0.0288985 |
| RPS27 | ribosomal protein S27 | 0.0288388 |
| ELF3 | E74-like factor 3 (ets domain transcription factor, epithelial-specific ) | 0.0285241 |
| DYNC1H1 | dynein, cytoplasmic 1, heavy chain 1 | 0.0278989 |
| TJP1 | tight junction protein 1 | 0.0276863 |
| USP53 | ubiquitin specific peptidase 53 | 0.0276684 |
| SDC4 | syndecan 4 | 0.02738 |
| ACTN1 | actinin, alpha 1 | 0.0272516 |
| PPARG | peroxisome proliferator-activated receptor gamma | 0.0272184 |
| CALR | calreticulin | 0.026923 |
| RPS3 | ribosomal protein S3 | 0.0268531 |
| ZBTB38 | zinc finger and BTB domain containing 38 | 0.0268208 |
| IFI27 | interferon, alpha-inducible protein 27 | 0.0266401 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | 0.0262524 |
| ANXA1 | annexin A1 | 0.0261809 |
| AFF4 | AF4/FMR2 family, member 4 | 0.0261191 |
| AGO2 | argonaute RISC catalytic component 2 | 0.0258565 |
| TOP1 | topoisomerase (DNA) I | 0.0256444 |
| KRT18 | keratin 18, type I | 0.0256059 |
| TPT1 | tumor protein, translationally-controlled 1 | 0.0255332 |
| S100A10 | S100 calcium binding protein A10 | 0.0255045 |
| ESRP1 | epithelial splicing regulatory protein 1 | 0.0254784 |
| SH3KBP1 | SH3-domain kinase binding protein 1 | 0.0251381 |
| TMSB10 | thymosin beta 10 | 0.025133 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.0249681 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0247474 |
| YBX1 | Y box binding protein 1 | 0.0243983 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.023545 |
| Symbol | Name | Standardized Value |
|---|---|---|
| FN1 | fibronectin 1 | -0.184449 |
| LPP | LIM domain containing preferred translocation partner in lipoma | -0.156623 |
| FNDC3B | fibronectin type III domain containing 3B | -0.119835 |
| POTEF | POTE ankyrin domain family, member F | -0.119813 |
| LIMCH1 | LIM and calponin homology domains 1 | -0.0918401 |
| ASPH | aspartate beta-hydroxylase | -0.0910255 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | -0.0702266 |
| SLC5A3 | solute carrier family 5 (sodium/myo-inositol cotransporter), member 3 | -0.0658667 |
| PDLIM5 | PDZ and LIM domain 5 | -0.0652353 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0621266 |
| VCL | vinculin | -0.061428 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.0563054 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.055873 |
| GOLGA4 | golgin A4 | -0.052121 |
| S100A6 | S100 calcium binding protein A6 | -0.0491837 |
| PGK1 | phosphoglycerate kinase 1 | -0.0456019 |
| AP3B1 | adaptor-related protein complex 3, beta 1 subunit | -0.0451339 |
| SEC24D | SEC24 family member D | -0.0447363 |
| EFNA5 | ephrin-A5 | -0.0444716 |
| EIF4G2 | eukaryotic translation initiation factor 4 gamma, 2 | -0.0441232 |
| ARHGAP20 | Rho GTPase activating protein 20 | -0.0439285 |
| FAM3C | family with sequence similarity 3, member C | -0.0429608 |
| ACTG1 | actin gamma 1 | -0.0429011 |
| F3 | coagulation factor III (thromboplastin, tissue factor) | -0.0426957 |
| PLSCR1 | phospholipid scramblase 1 | -0.0426475 |
| CD47 | CD47 molecule | -0.0424956 |
| CCND1 | cyclin D1 | -0.0420619 |
| CTSD | cathepsin D | -0.04113 |
| RAI14 | retinoic acid induced 14 | -0.0408316 |
| LOC112694756 | uncharaterized LOC112694756 | -0.040039 |
| TAPBP | TAP binding protein (tapasin) | -0.0398229 |
| TMEM263 | transmembrane protein 263 | -0.039515 |
| HERC5 | HECT and RLD domain containing E3 ubiquitin protein ligase 5 | -0.0391804 |
| RCOR1 | REST corepressor 1 | -0.0388777 |
| RHOA | ras homolog family member A | -0.0381071 |
| ADAM9 | ADAM metallopeptidase domain 9 | -0.0378999 |
| VEGFA | vascular endothelial growth factor A | -0.0358706 |
| PTK2 | protein tyrosine kinase 2 | -0.0357593 |
| UBC | ubiquitin C | -0.0357341 |
| DSTN | destrin (actin depolymerizing factor) | -0.0354247 |
| FUT8 | fucosyltransferase 8 (alpha (1,6) fucosyltransferase) | -0.0353307 |
| HMGA1 | high mobility group AT-hook 1 | -0.0350697 |
| GFPT1 | glutamine--fructose-6-phosphate transaminase 1 | -0.0337007 |
| TTC3 | tetratricopeptide repeat domain 3 | -0.0336181 |
| CRABP2 | cellular retinoic acid binding protein 2 | -0.0330024 |
| SETD5 | SET domain containing 5 | -0.0325982 |
| MAML2 | mastermind-like 2 (Drosophila) | -0.0324932 |
| TFG | TRK-fused gene | -0.0319721 |
| CDC50A | cell division cycle 50 P4-ATPase accessory subunit A | -0.0313428 |
| SCFD1 | sec1 family domain containing 1 | -0.03078 |
| WARS1 | tryptophanyl-tRNA synthetase 1 | -0.0303675 |
| SLMAP | sarcolemma associated protein | -0.0300815 |
| GNAS | GNAS complex locus | -0.0300732 |
| MRPS6 | mitochondrial ribosomal protein S6 | -0.0298009 |
| SLC20A2 | solute carrier family 20 (phosphate transporter), member 2 | -0.0293409 |
| ADAR | adenosine deaminase, RNA-specific | -0.0287606 |
| STRN3 | striatin, calmodulin binding protein 3 | -0.0284146 |
| SLC34A2 | solute carrier family 34 (type II sodium/phosphate cotransporter), member 2 | -0.0282514 |
| PKM | pyruvate kinase, muscle | -0.0281479 |
| ANXA2 | annexin A2 | -0.0280489 |
| ATP5F1B | ATP synthase F1 subunit beta | -0.0277627 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.0276635 |
| MCU | mitochondrial calcium uniporter | -0.027571 |
| CD46 | CD46 molecule, complement regulatory protein | -0.027474 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | -0.0272483 |
| MAP3K13 | mitogen-activated protein kinase kinase kinase 13 | -0.0269727 |
| ATP11A | ATPase, class VI, type 11A | -0.0269046 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | -0.025876 |
| LGALS3BP | lectin, galactoside-binding, soluble, 3 binding protein | -0.0255854 |
| CNOT2 | CCR4-NOT transcription complex, subunit 2 | -0.0254881 |
| RIGI | RNA sensor RIG-I | -0.0254431 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | -0.0252133 |
| EPCAM | epithelial cell adhesion molecule | -0.0250768 |
| OAS3 | 2'-5'-oligoadenylate synthetase 3, 100kDa | -0.0247503 |
| SSBP2 | single-stranded DNA binding protein 2 | -0.0245173 |
| TPM4 | tropomyosin 4 | -0.024507 |
| SAMD4A | sterile alpha motif domain containing 4A | -0.0244521 |
| RPLP0 | ribosomal protein, large, P0 | -0.0243896 |
| MYH9 | myosin, heavy chain 9, non-muscle | -0.0241195 |
| LY6E | lymphocyte antigen 6 complex, locus E | -0.0239037 |
| KRT8 | keratin 8, type II | -0.0238502 |
| SPATS2L | spermatogenesis associated, serine-rich 2-like | -0.0238106 |
| PRRC1 | proline-rich coiled-coil 1 | -0.0235132 |
| CCNG2 | cyclin G2 | -0.0234787 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | -0.0234103 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0233362 |
| DDX60 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 60 | -0.023315 |
| CCNL1 | cyclin L1 | -0.0232596 |
| ZNF207 | zinc finger protein 207 | -0.0229392 |
| SP100 | SP100 nuclear antigen | -0.022929 |
| DDX60L | DEAD (Asp-Glu-Ala-Asp) box polypeptide 60-like | -0.0229253 |
| RBMS3 | RNA binding motif, single stranded interacting protein 3 | -0.0227871 |
| TBL1XR1 | transducin (beta)-like 1 X-linked receptor 1 | -0.0225374 |
| GOLT1B | golgi transport 1B | -0.0224428 |
| FOSL1 | FOS-like antigen 1 | -0.0223718 |
| MON2 | MON2 homolog (S. cerevisiae) | -0.0221157 |
| PPP1R15B | protein phosphatase 1, regulatory subunit 15B | -0.0219054 |
| ARF4 | ADP-ribosylation factor 4 | -0.0218734 |
| PALLD | palladin, cytoskeletal associated protein | -0.0217989 |
| MSMO1 | methylsterol monooxygenase 1 | -0.0216685 |
