| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | (R)-Verapamil (hydrochloride) perturbation in NCI-H460 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the (R)-Verapamil (hydrochloride)_NCI-H460 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| DST | dystonin | 0.130503 |
| KYNU | kynureninase | 0.0903728 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | 0.084892 |
| PM20D1 | peptidase M20 domain containing 1 | 0.0814648 |
| COL8A1 | collagen, type VIII, alpha 1 | 0.0805659 |
| PDE10A | phosphodiesterase 10A | 0.0722434 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | 0.0640079 |
| PRKN | parkin RBR E3 ubiquitin protein ligase | 0.0639917 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.0638372 |
| CTIF | CBP80/20-dependent translation initiation factor | 0.0621154 |
| GRAMD1B | GRAM domain containing 1B | 0.0616876 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0594377 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | 0.0581672 |
| RPS4X | ribosomal protein S4, X-linked | 0.0577861 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | 0.055606 |
| SRGAP1 | SLIT-ROBO Rho GTPase activating protein 1 | 0.0546873 |
| PDLIM5 | PDZ and LIM domain 5 | 0.0544603 |
| SMOC1 | SPARC related modular calcium binding 1 | 0.0523338 |
| INTS6 | integrator complex subunit 6 | 0.048433 |
| ATP1B3 | ATPase, Na+/K+ transporting, beta 3 polypeptide | 0.0461323 |
| SMAD2 | SMAD family member 2 | 0.0444558 |
| VCL | vinculin | 0.0433635 |
| TGFBR1 | transforming growth factor, beta receptor 1 | 0.0423524 |
| PLEKHA5 | pleckstrin homology domain containing, family A member 5 | 0.0414521 |
| MCL1 | myeloid cell leukemia 1 | 0.0410697 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | 0.0402577 |
| RPL23 | ribosomal protein L23 | 0.0392302 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0365359 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.0348821 |
| RPS12 | ribosomal protein S12 | 0.0347884 |
| FLNB | filamin B, beta | 0.0347078 |
| SLC2A13 | solute carrier family 2 (facilitated glucose transporter), member 13 | 0.0342554 |
| PCBP2 | poly(rC) binding protein 2 | 0.0341647 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | 0.0340381 |
| DOCK5 | dedicator of cytokinesis 5 | 0.031362 |
| ATP2B1 | ATPase, Ca++ transporting, plasma membrane 1 | 0.0313272 |
| ASPH | aspartate beta-hydroxylase | 0.0312872 |
| SLC38A2 | solute carrier family 38, member 2 | 0.0310962 |
| PRRC2C | proline-rich coiled-coil 2C | 0.0309987 |
| RPS17 | ribosomal protein S17 | 0.0308378 |
| ATXN1 | ataxin 1 | 0.0303143 |
| ADARB2 | adenosine deaminase, RNA-specific, B2 (non-functional) | 0.0299074 |
| DOCK4 | dedicator of cytokinesis 4 | 0.0296667 |
| BMP6 | bone morphogenetic protein 6 | 0.0291153 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | 0.0290632 |
| MCTP1 | multiple C2 domains, transmembrane 1 | 0.0274932 |
| EPHA4 | EPH receptor A4 | 0.0274901 |
| GPC6 | glypican 6 | 0.0274264 |
| NT5C2 | 5'-nucleotidase, cytosolic II | 0.0273463 |
| SLF1 | SMC5-SMC6 complex localization factor 1 | 0.0272024 |
| CHD1 | chromodomain helicase DNA binding protein 1 | 0.0268719 |
| USP34 | ubiquitin specific peptidase 34 | 0.0261841 |
| HUWE1 | HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase | 0.0261465 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | 0.0251963 |
| PRELID2 | PRELI domain containing 2 | 0.0249985 |
| DYNC1H1 | dynein, cytoplasmic 1, heavy chain 1 | 0.0247542 |
| MORF4L2 | mortality factor 4 like 2 | 0.0246038 |
| CDH11 | cadherin 11, type 2, OB-cadherin (osteoblast) | 0.0243124 |
| BASP1 | brain abundant, membrane attached signal protein 1 | 0.0242696 |
| MAML3 | mastermind-like 3 (Drosophila) | 0.0241812 |
| CREB3L2 | cAMP responsive element binding protein 3-like 2 | 0.0239573 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | 0.023669 |
| PTPRM | protein tyrosine phosphatase, receptor type, M | 0.0234624 |
| SAMD4A | sterile alpha motif domain containing 4A | 0.0221446 |
| NRXN3 | neurexin 3 | 0.0220491 |
| ANTXR1 | anthrax toxin receptor 1 | 0.0217799 |
| ADARB1 | adenosine deaminase, RNA-specific, B1 | 0.0215089 |
| EXT1 | exostosin glycosyltransferase 1 | 0.0213943 |
| PDE7B | phosphodiesterase 7B | 0.0213672 |
| FMNL2 | formin-like 2 | 0.0211606 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.020512 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0204837 |
| AADAC | arylacetamide deacetylase | 0.0204105 |
| OGDH | oxoglutarate (alpha-ketoglutarate) dehydrogenase (lipoamide) | 0.020215 |
| FLRT2 | fibronectin leucine rich transmembrane protein 2 | 0.0201771 |
| SPTAN1 | spectrin, alpha, non-erythrocytic 1 | 0.0198826 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0196812 |
| SFPQ | splicing factor proline/glutamine-rich | 0.019639 |
| FER | fer (fps/fes related) tyrosine kinase | 0.0194561 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | 0.0193611 |
| CARD16 | caspase recruitment domain family, member 16 | 0.0189733 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0187901 |
| NCAPG2 | non-SMC condensin II complex, subunit G2 | 0.0186908 |
| RAD51B | RAD51 paralog B | 0.0186303 |
| VPS13B | vacuolar protein sorting 13 homolog B (yeast) | 0.0184328 |
| MAFK | v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog K | 0.0181479 |
| PLCB4 | phospholipase C, beta 4 | 0.018028 |
| RPL17-C18ORF32 | RPL17-C18orf32 readthrough | 0.0180164 |
| MARCHF1 | membrane associated ring-CH-type finger 1 | 0.0178982 |
| AGTPBP1 | ATP/GTP binding protein 1 | 0.0178631 |
| ATXN7 | ataxin 7 | 0.0178573 |
| ATP5F1E | ATP synthase F1 subunit epsilon | 0.0178228 |
| GLS2 | glutaminase 2 (liver, mitochondrial) | 0.0178069 |
| CEP72 | centrosomal protein 72kDa | 0.0177311 |
| HNRNPC | heterogeneous nuclear ribonucleoprotein C (C1/C2) | 0.0177296 |
| RCOR1 | REST corepressor 1 | 0.0176972 |
| CNOT1 | CCR4-NOT transcription complex, subunit 1 | 0.0176907 |
| CREBBP | CREB binding protein | 0.0176898 |
| CTBP2 | C-terminal binding protein 2 | 0.0175826 |
| UMAD1 | UBAP1-MVB12-associated (UMA) domain containing 1 | 0.017535 |
| Symbol | Name | Standardized Value |
|---|---|---|
| FN1 | fibronectin 1 | -0.463945 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.207796 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.155241 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.1447 |
| VIM | vimentin | -0.123221 |
| CYP1B1 | cytochrome P450, family 1, subfamily B, polypeptide 1 | -0.0919181 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.0887913 |
| RASSF8 | Ras association (RalGDS/AF-6) domain family (N-terminal) member 8 | -0.0830232 |
| SEMA3A | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A | -0.0697558 |
| CANX | calnexin | -0.0680589 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0672995 |
| PTMA | prothymosin, alpha | -0.0637515 |
| PGK1 | phosphoglycerate kinase 1 | -0.0589368 |
| STC1 | stanniocalcin 1 | -0.0571485 |
| PLCB1 | phospholipase C, beta 1 (phosphoinositide-specific) | -0.0569008 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.0526189 |
| WARS1 | tryptophanyl-tRNA synthetase 1 | -0.0499755 |
| CTSL | cathepsin L | -0.0476601 |
| PCBP3 | poly(rC) binding protein 3 | -0.0473771 |
| TFPI2 | tissue factor pathway inhibitor 2 | -0.0460558 |
| TGFBI | transforming growth factor, beta-induced, 68kDa | -0.0460185 |
| SOX4 | SRY (sex determining region Y)-box 4 | -0.0454835 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.0454695 |
| S100A6 | S100 calcium binding protein A6 | -0.0451728 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | -0.0449792 |
| COL5A2 | collagen, type V, alpha 2 | -0.043749 |
| NALF1 | NALCN channel auxiliary factor 1 | -0.0435888 |
| ADAMTS6 | ADAM metallopeptidase with thrombospondin type 1 motif, 6 | -0.0435775 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | -0.0421857 |
| CDH13 | cadherin 13 | -0.0413184 |
| BZW1 | basic leucine zipper and W2 domains 1 | -0.0403611 |
| TENM3 | teneurin transmembrane protein 3 | -0.0397067 |
| OSMR | oncostatin M receptor | -0.0393445 |
| HLA-B | major histocompatibility complex, class I, B | -0.0385374 |
| FTL | ferritin, light polypeptide | -0.0384435 |
| SOD2 | superoxide dismutase 2, mitochondrial | -0.0382921 |
| LOC112694756 | uncharaterized LOC112694756 | -0.038032 |
| TMX4 | thioredoxin-related transmembrane protein 4 | -0.0366988 |
| KPNB1 | karyopherin (importin) beta 1 | -0.0365885 |
| LMAN1 | lectin, mannose-binding, 1 | -0.035904 |
| SEMA3D | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3D | -0.0358891 |
| GNAS | GNAS complex locus | -0.0352102 |
| VDAC1 | voltage-dependent anion channel 1 | -0.0350644 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.0329749 |
| TPM4 | tropomyosin 4 | -0.0329007 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0322317 |
| IFIT3 | interferon-induced protein with tetratricopeptide repeats 3 | -0.0320273 |
| PYGL | phosphorylase, glycogen, liver | -0.0315843 |
| IER3 | immediate early response 3 | -0.0314654 |
| KDM3A | lysine (K)-specific demethylase 3A | -0.0308941 |
| ENO1 | enolase 1, (alpha) | -0.030627 |
| DGKD | diacylglycerol kinase, delta 130kDa | -0.0305903 |
| RPLP0 | ribosomal protein, large, P0 | -0.0301785 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.0300301 |
| SLC7A2 | solute carrier family 7 (cationic amino acid transporter, y+ system), member 2 | -0.0298611 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | -0.0294074 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0291558 |
| PMAIP1 | phorbol-12-myristate-13-acetate-induced protein 1 | -0.0283903 |
| DDX60 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 60 | -0.0282549 |
| CNOT2 | CCR4-NOT transcription complex, subunit 2 | -0.0276959 |
| TMSB4X | thymosin beta 4, X-linked | -0.0276911 |
| SERPINB2 | serpin peptidase inhibitor, clade B (ovalbumin), member 2 | -0.0276868 |
| PJA2 | praja ring finger 2, E3 ubiquitin protein ligase | -0.0275147 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | -0.0274664 |
| OGA | O-GlcNAcase | -0.0272387 |
| RIGI | RNA sensor RIG-I | -0.0271165 |
| PTGR1 | prostaglandin reductase 1 | -0.0268742 |
| BTG1 | B-cell translocation gene 1, anti-proliferative | -0.026755 |
| BMERB1 | bMERB domain containing 1 | -0.0265646 |
| ERC2 | ELKS/RAB6-interacting/CAST family member 2 | -0.0261864 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | -0.0260243 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | -0.0259429 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.025611 |
| FOXC1 | forkhead box C1 | -0.0255505 |
| RPLP1 | ribosomal protein, large, P1 | -0.0254445 |
| RBMS3 | RNA binding motif, single stranded interacting protein 3 | -0.0251 |
| BNIP3 | BCL2/adenovirus E1B 19kDa interacting protein 3 | -0.0248789 |
| SLC16A6 | solute carrier family 16, member 6 | -0.0248553 |
| SMYD3 | SET and MYND domain containing 3 | -0.0246649 |
| CCDC68 | coiled-coil domain containing 68 | -0.0245596 |
| MAP3K20 | mitogen-activated protein kinase kinase kinase 20 | -0.0245354 |
| AFF4 | AF4/FMR2 family, member 4 | -0.0243206 |
| NCKAP5 | NCK-associated protein 5 | -0.0241457 |
| RHOB | ras homolog family member B | -0.0239498 |
| UNC5D | unc-5 homolog D (C. elegans) | -0.0237993 |
| HILPDA | hypoxia inducible lipid droplet-associated | -0.0237719 |
| KDM5B | lysine (K)-specific demethylase 5B | -0.0237007 |
| SLC25A37 | solute carrier family 25 (mitochondrial iron transporter), member 37 | -0.0236523 |
| ANXA2 | annexin A2 | -0.0235333 |
| UBC | ubiquitin C | -0.0233319 |
| NPEPPS | aminopeptidase puromycin sensitive | -0.0231194 |
| FAM13A | family with sequence similarity 13, member A | -0.0231029 |
| PNRC1 | proline-rich nuclear receptor coactivator 1 | -0.0230677 |
| RPL39 | ribosomal protein L39 | -0.0229712 |
| SPAG9 | sperm associated antigen 9 | -0.0228746 |
| CTNND2 | catenin (cadherin-associated protein), delta 2 | -0.0228376 |
| TBXT | T-box transcription factor T | -0.0228171 |
| GFPT1 | glutamine--fructose-6-phosphate transaminase 1 | -0.0226619 |
| OASL | 2'-5'-oligoadenylate synthetase-like | -0.0225254 |
| SCCPDH | saccharopine dehydrogenase (putative) | -0.0224829 |
