| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | (R)-Verapamil (hydrochloride) perturbation in NCI-H596 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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134 genes differentially expressed following the (R)-Verapamil (hydrochloride)_NCI-H596 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | 0.285761 |
| EGFR | epidermal growth factor receptor | 0.210079 |
| DOCK5 | dedicator of cytokinesis 5 | 0.177613 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.173237 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | 0.16781 |
| PLCB1 | phospholipase C, beta 1 (phosphoinositide-specific) | 0.165566 |
| PRRC2C | proline-rich coiled-coil 2C | 0.124815 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | 0.121769 |
| MBNL1 | muscleblind-like splicing regulator 1 | 0.121433 |
| SBF2 | SET binding factor 2 | 0.0952841 |
| FLNB | filamin B, beta | 0.0890171 |
| KMT2C | lysine (K)-specific methyltransferase 2C | 0.0848294 |
| FN1 | fibronectin 1 | 0.0839443 |
| PTK2 | protein tyrosine kinase 2 | 0.0807345 |
| MGAT5 | mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase | 0.0801737 |
| TEAD1 | TEA domain family member 1 (SV40 transcriptional enhancer factor) | 0.0774537 |
| KANSL1 | KAT8 regulatory NSL complex subunit 1 | 0.0733578 |
| LPP | LIM domain containing preferred translocation partner in lipoma | 0.0730265 |
| ARPC1B | actin related protein 2/3 complex, subunit 1B, 41kDa | 0.0729599 |
| FGFR1 | fibroblast growth factor receptor 1 | 0.0716323 |
| TMSB10 | thymosin beta 10 | 0.0712953 |
| MED13 | mediator complex subunit 13 | 0.0655302 |
| LOC102724023 | ES1 protein homolog, mitochondrial | 0.0639219 |
| CD44 | CD44 molecule (Indian blood group) | 0.0595286 |
| FNDC3A | fibronectin type III domain containing 3A | 0.0560529 |
| KDM5B | lysine (K)-specific demethylase 5B | 0.0545392 |
| SMURF2 | SMAD specific E3 ubiquitin protein ligase 2 | 0.0526967 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | 0.0522125 |
| RPS8 | ribosomal protein S8 | 0.0507704 |
| RAB7A | RAB7A, member RAS oncogene family | 0.0478384 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.0473388 |
| EGR1 | early growth response 1 | 0.0461432 |
| JMJD1C | jumonji domain containing 1C | 0.044753 |
| SMYD3 | SET and MYND domain containing 3 | 0.0441757 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | 0.0410729 |
| LMO7 | LIM domain 7 | 0.0403636 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | 0.0385416 |
| RPL23 | ribosomal protein L23 | 0.0380219 |
| DSPP | dentin sialophosphoprotein | 0.0370298 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | 0.0367573 |
| TIMP3 | TIMP metallopeptidase inhibitor 3 | 0.0354191 |
| HNRNPC | heterogeneous nuclear ribonucleoprotein C (C1/C2) | 0.0341542 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | 0.0341405 |
| PUM2 | pumilio RNA-binding family member 2 | 0.0319502 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | 0.0317344 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0297922 |
| NDRG1 | N-myc downstream regulated 1 | 0.0291958 |
| MED13L | mediator complex subunit 13-like | 0.0272552 |
| RPS6 | ribosomal protein S6 | 0.0267327 |
| MAML2 | mastermind-like 2 (Drosophila) | 0.0263887 |
| ARFGEF1 | ADP-ribosylation factor guanine nucleotide-exchange factor 1 (brefeldin A-inhibited) | 0.0241159 |
| UACA | uveal autoantigen with coiled-coil domains and ankyrin repeats | 0.0177799 |
| TPT1 | tumor protein, translationally-controlled 1 | 0.015825 |
| MCL1 | myeloid cell leukemia 1 | 0.0132176 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0126339 |
| ANXA2 | annexin A2 | 0.0123826 |
| ATXN1 | ataxin 1 | 0.00930063 |
| RPS12 | ribosomal protein S12 | 0.00804047 |
| COL5A1 | collagen, type V, alpha 1 | 0.00695693 |
| KDM2A | lysine (K)-specific demethylase 2A | 0.00692381 |
| NUMB | numb homolog (Drosophila) | 0.00686177 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | 0.00680403 |
| BPTF | bromodomain PHD finger transcription factor | 0.00509315 |
| RPS19 | ribosomal protein S19 | 0.00451433 |
| POTEF | POTE ankyrin domain family, member F | 0.00407716 |
| ASH1L | ash1 (absent, small, or homeotic)-like (Drosophila) | 0.00364549 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.00351509 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.00184708 |
| ERBIN | erbb2 interacting protein | 1.79736E-4 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.279962 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.194978 |
| VCL | vinculin | -0.163255 |
| CDH13 | cadherin 13 | -0.121256 |
| DST | dystonin | -0.117709 |
| PDE10A | phosphodiesterase 10A | -0.111273 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.108709 |
| PCBP3 | poly(rC) binding protein 3 | -0.0992787 |
| SND1 | staphylococcal nuclease and tudor domain containing 1 | -0.0928586 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0892426 |
| PTMA | prothymosin, alpha | -0.0883437 |
| GPC6 | glypican 6 | -0.0870185 |
| SETD5 | SET domain containing 5 | -0.0822433 |
| NAV2 | neuron navigator 2 | -0.0808242 |
| ADARB2 | adenosine deaminase, RNA-specific, B2 (non-functional) | -0.0801596 |
| NHSL1 | NHS-like 1 | -0.0781814 |
| EFNA5 | ephrin-A5 | -0.0751027 |
| ASPH | aspartate beta-hydroxylase | -0.0720163 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | -0.0715729 |
| TANC2 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 | -0.0675752 |
| VIM | vimentin | -0.0667938 |
| NALF1 | NALCN channel auxiliary factor 1 | -0.063993 |
| ANKRD11 | ankyrin repeat domain 11 | -0.0615185 |
| RAP1B | RAP1B, member of RAS oncogene family | -0.0572534 |
| AUTS2 | autism susceptibility candidate 2 | -0.0535429 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | -0.0505563 |
| EXT1 | exostosin glycosyltransferase 1 | -0.0503976 |
| HMGA2 | high mobility group AT-hook 2 | -0.048504 |
| PARD3 | par-3 family cell polarity regulator | -0.0480168 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | -0.047913 |
| PCCA | propionyl CoA carboxylase, alpha polypeptide | -0.0445701 |
| EEF2 | eukaryotic translation elongation factor 2 | -0.0441342 |
| STC1 | stanniocalcin 1 | -0.0428852 |
| RPL35A | ribosomal protein L35a | -0.0413958 |
| ROBO2 | roundabout, axon guidance receptor, homolog 2 (Drosophila) | -0.0403429 |
| RORA | RAR-related orphan receptor A | -0.0391228 |
| IGF2 | insulin-like growth factor 2 | -0.037598 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | -0.03663 |
| FTL | ferritin, light polypeptide | -0.0359555 |
| GRIK1 | glutamate receptor, ionotropic, kainate 1 | -0.0334287 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.0311625 |
| RPS25 | ribosomal protein S25 | -0.0308049 |
| SGIP1 | SH3-domain GRB2-like (endophilin) interacting protein 1 | -0.0288661 |
| NKD1 | naked cuticle homolog 1 (Drosophila) | -0.02847 |
| ROBO1 | roundabout, axon guidance receptor, homolog 1 (Drosophila) | -0.0280383 |
| FNDC3B | fibronectin type III domain containing 3B | -0.0265888 |
| RAD51B | RAD51 paralog B | -0.0262162 |
| SIPA1L3 | signal-induced proliferation-associated 1 like 3 | -0.0258485 |
| PTPRM | protein tyrosine phosphatase, receptor type, M | -0.025619 |
| MT2A | metallothionein 2A | -0.0253662 |
| MYCBP2 | MYC binding protein 2, E3 ubiquitin protein ligase | -0.0219173 |
| TBC1D22A | TBC1 domain family, member 22A | -0.0209853 |
| NSMCE2 | non-SMC element 2, MMS21 homolog (S. cerevisiae) | -0.0204425 |
| PRKCA | protein kinase C, alpha | -0.018081 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.0180032 |
| VMP1 | vacuole membrane protein 1 | -0.0164821 |
| MAGI2 | membrane associated guanylate kinase, WW and PDZ domain containing 2 | -0.0157279 |
| SEC31A | SEC31 homolog A (S. cerevisiae) | -0.0125803 |
| MYO1E | myosin IE | -0.010198 |
| ANKHD1 | ankyrin repeat and KH domain containing 1 | -0.0101774 |
| LDHA | lactate dehydrogenase A | -0.00954185 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.00940369 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.00938337 |
| MKLN1 | muskelin 1, intracellular mediator containing kelch motifs | -0.00819106 |
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa | -0.00354489 |
