| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | (R)-Verapamil (hydrochloride) perturbation in NCI-H661 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the (R)-Verapamil (hydrochloride)_NCI-H661 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| CDH6 | cadherin 6, type 2, K-cadherin (fetal kidney) | 0.097644 |
| ERBB4 | erb-b2 receptor tyrosine kinase 4 | 0.0829283 |
| UACA | uveal autoantigen with coiled-coil domains and ankyrin repeats | 0.0754795 |
| CDH10 | cadherin 10, type 2 (T2-cadherin) | 0.0648137 |
| COL11A1 | collagen, type XI, alpha 1 | 0.0635504 |
| CADM2 | cell adhesion molecule 2 | 0.057538 |
| FOXP2 | forkhead box P2 | 0.0527341 |
| RBMS3 | RNA binding motif, single stranded interacting protein 3 | 0.0497532 |
| HDAC9 | histone deacetylase 9 | 0.0473013 |
| SAMD4A | sterile alpha motif domain containing 4A | 0.0364515 |
| TOX | thymocyte selection-associated high mobility group box | 0.0341154 |
| TENM3 | teneurin transmembrane protein 3 | 0.0312069 |
| RALGAPA1 | Ral GTPase activating protein, alpha subunit 1 (catalytic) | 0.0310043 |
| CTNNA2 | catenin (cadherin-associated protein), alpha 2 | 0.0298416 |
| PCLO | piccolo presynaptic cytomatrix protein | 0.0298331 |
| ANK2 | ankyrin 2, neuronal | 0.0296048 |
| MEIS2 | Meis homeobox 2 | 0.0289529 |
| MBD5 | methyl-CpG binding domain protein 5 | 0.0288298 |
| DOCK5 | dedicator of cytokinesis 5 | 0.027385 |
| KCTD16 | potassium channel tetramerization domain containing 16 | 0.0272512 |
| PARD3B | par-3 family cell polarity regulator beta | 0.02711 |
| CDH19 | cadherin 19, type 2 | 0.0270721 |
| USP25 | ubiquitin specific peptidase 25 | 0.0263745 |
| SMYD3 | SET and MYND domain containing 3 | 0.0262366 |
| LPIN2 | lipin 2 | 0.0260132 |
| GREB1L | growth regulation by estrogen in breast cancer-like | 0.0246622 |
| TTC3 | tetratricopeptide repeat domain 3 | 0.0244224 |
| FN1 | fibronectin 1 | 0.0243314 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0237391 |
| ARHGAP24 | Rho GTPase activating protein 24 | 0.0232218 |
| SIPA1L1 | signal-induced proliferation-associated 1 like 1 | 0.0223841 |
| CTNNA3 | catenin (cadherin-associated protein), alpha 3 | 0.0220428 |
| SMG1 | SMG1 phosphatidylinositol 3-kinase-related kinase | 0.0215328 |
| ELOF1 | elongation factor 1 homolog (S. cerevisiae) | 0.0211013 |
| PBX3 | pre-B-cell leukemia homeobox 3 | 0.0210698 |
| ZEB2 | zinc finger E-box binding homeobox 2 | 0.0208833 |
| CNTN6 | contactin 6 | 0.0205835 |
| ZC3H12B | zinc finger CCCH-type containing 12B | 0.0205537 |
| SPIDR | scaffolding protein involved in DNA repair | 0.0201676 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.0200653 |
| NCOA1 | nuclear receptor coactivator 1 | 0.0194163 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | 0.0194021 |
| ATXN1 | ataxin 1 | 0.0193102 |
| ARID1B | AT rich interactive domain 1B (SWI1-like) | 0.0191088 |
| USP9X | ubiquitin specific peptidase 9, X-linked | 0.0189238 |
| ZFHX4 | zinc finger homeobox 4 | 0.0187044 |
| FER | fer (fps/fes related) tyrosine kinase | 0.0184884 |
| RAPGEF2 | Rap guanine nucleotide exchange factor (GEF) 2 | 0.0183346 |
| FBXL17 | F-box and leucine-rich repeat protein 17 | 0.0177447 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0174015 |
| PCDH7 | protocadherin 7 | 0.0172702 |
| NHSL1 | NHS-like 1 | 0.0172689 |
| AUTS2 | autism susceptibility candidate 2 | 0.0171906 |
| INTS6 | integrator complex subunit 6 | 0.0171517 |
| WWC2 | WW and C2 domain containing 2 | 0.0170371 |
| MED12L | mediator complex subunit 12-like | 0.017036 |
| GPC4 | glypican 4 | 0.0166647 |
| USP34 | ubiquitin specific peptidase 34 | 0.0166158 |
| PCDH9 | protocadherin 9 | 0.0166091 |
| CDC42BPA | CDC42 binding protein kinase alpha (DMPK-like) | 0.0165329 |
| KDM4C | lysine (K)-specific demethylase 4C | 0.0164339 |
| CAMTA1 | calmodulin binding transcription activator 1 | 0.0159555 |
| IGF2BP3 | insulin-like growth factor 2 mRNA binding protein 3 | 0.0159267 |
| SLC44A5 | solute carrier family 44, member 5 | 0.0156161 |
| RERE | arginine-glutamic acid dipeptide (RE) repeats | 0.0155685 |
| SGCG | sarcoglycan, gamma (35kDa dystrophin-associated glycoprotein) | 0.0155332 |
| CHD1 | chromodomain helicase DNA binding protein 1 | 0.0152476 |
| SMAD6 | SMAD family member 6 | 0.0150802 |
| TBL1X | transducin (beta)-like 1X-linked | 0.0150415 |
| RCOR1 | REST corepressor 1 | 0.0150173 |
| PCDH18 | protocadherin 18 | 0.0148869 |
| NEBL | nebulette | 0.0146737 |
| PRELID2 | PRELI domain containing 2 | 0.0145048 |
| WNK1 | WNK lysine deficient protein kinase 1 | 0.0144588 |
| BLTP1 | bridge-like lipid transfer protein family member 1 | 0.0144498 |
| CLIC4 | chloride intracellular channel 4 | 0.0144485 |
| CPNE1 | copine I | 0.014356 |
| DDAH1 | dimethylarginine dimethylaminohydrolase 1 | 0.0142932 |
| NALF1 | NALCN channel auxiliary factor 1 | 0.0142502 |
| TANC1 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 1 | 0.0142399 |
| LRMDA | leucine rich melanocyte differentiation associated | 0.0141818 |
| CABLES1 | Cdk5 and Abl enzyme substrate 1 | 0.014157 |
| ARFGEF1 | ADP-ribosylation factor guanine nucleotide-exchange factor 1 (brefeldin A-inhibited) | 0.0141199 |
| PRTG | protogenin | 0.0140803 |
| SERTAD2 | SERTA domain containing 2 | 0.0140116 |
| EFNB2 | ephrin-B2 | 0.0139461 |
| INPP4B | inositol polyphosphate-4-phosphatase, type II, 105kDa | 0.0139327 |
| BMPR1A | bone morphogenetic protein receptor, type IA | 0.0138905 |
| ERCC6L2 | excision repair cross-complementation group 6-like 2 | 0.0138141 |
| TRIM2 | tripartite motif containing 2 | 0.0138074 |
| EIF4G3 | eukaryotic translation initiation factor 4 gamma, 3 | 0.0137145 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | 0.0136333 |
| CSRNP3 | cysteine-serine-rich nuclear protein 3 | 0.0136295 |
| NTM | neurotrimin | 0.0135472 |
| ARID1A | AT rich interactive domain 1A (SWI-like) | 0.0134882 |
| TIAM1 | T-cell lymphoma invasion and metastasis 1 | 0.0134004 |
| MCL1 | myeloid cell leukemia 1 | 0.0132598 |
| ANO6 | anoctamin 6 | 0.0132185 |
| FRYL | FRY-like | 0.0131969 |
| FKBP5 | FK506 binding protein 5 | 0.0131828 |
| Symbol | Name | Standardized Value |
|---|---|---|
| VIM | vimentin | -0.240576 |
| PTMA | prothymosin, alpha | -0.142358 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.121046 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | -0.110845 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.105861 |
| PEG10 | paternally expressed 10 | -0.100524 |
| TMSB10 | thymosin beta 10 | -0.0934167 |
| MKI67 | marker of proliferation Ki-67 | -0.087 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | -0.0846467 |
| TMSB4X | thymosin beta 4, X-linked | -0.0824573 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0783862 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | -0.0738941 |
| CENPF | centromere protein F, 350/400kDa | -0.0733917 |
| RPS16 | ribosomal protein S16 | -0.0728505 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.0725124 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | -0.0722742 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | -0.0711846 |
| SPAG9 | sperm associated antigen 9 | -0.0620106 |
| RPS6 | ribosomal protein S6 | -0.0594029 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | -0.0590051 |
| SRP54 | signal recognition particle 54kDa | -0.0570092 |
| ZNF292 | zinc finger protein 292 | -0.0555502 |
| TRIO | trio Rho guanine nucleotide exchange factor | -0.0543922 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0541777 |
| CENPE | centromere protein E, 312kDa | -0.0509091 |
| G2E3 | G2/M-phase specific E3 ubiquitin protein ligase | -0.0508792 |
| PFN1 | profilin 1 | -0.0507492 |
| MATR3 | matrin 3 | -0.0494512 |
| ATP5F1B | ATP synthase F1 subunit beta | -0.0490053 |
| GNAS | GNAS complex locus | -0.0486705 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.0477689 |
| ACTG1 | actin gamma 1 | -0.0470604 |
| KPNB1 | karyopherin (importin) beta 1 | -0.0462039 |
| RAD21 | RAD21 homolog (S. pombe) | -0.0453705 |
| YWHAB | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta | -0.0444645 |
| ANXA2 | annexin A2 | -0.044432 |
| CALR | calreticulin | -0.0440376 |
| CKAP2 | cytoskeleton associated protein 2 | -0.0438259 |
| COL1A2 | collagen, type I, alpha 2 | -0.043305 |
| MRPS30 | mitochondrial ribosomal protein S30 | -0.0427059 |
| HMGB1 | high mobility group box 1 | -0.0422208 |
| ZFAND3 | zinc finger, AN1-type domain 3 | -0.0418468 |
| ADAM9 | ADAM metallopeptidase domain 9 | -0.0416494 |
| SF3B1 | splicing factor 3b, subunit 1, 155kDa | -0.0408226 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | -0.0406524 |
| PGAP1 | post-GPI attachment to proteins 1 | -0.0405043 |
| COL3A1 | collagen, type III, alpha 1 | -0.0401397 |
| YES1 | YES proto-oncogene 1, Src family tyrosine kinase | -0.040084 |
| GPC3 | glypican 3 | -0.039346 |
| YWHAE | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon | -0.0392246 |
| TPX2 | TPX2, microtubule-associated | -0.0385289 |
| RTN4 | reticulon 4 | -0.0383472 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0378973 |
| NRG1 | neuregulin 1 | -0.0377472 |
| THBS1 | thrombospondin 1 | -0.0373151 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.037304 |
| PSMA7 | proteasome (prosome, macropain) subunit, alpha type, 7 | -0.0368083 |
| BMPR2 | bone morphogenetic protein receptor, type II (serine/threonine kinase) | -0.0367039 |
| PPP1R12A | protein phosphatase 1, regulatory subunit 12A | -0.0362569 |
| SF3B2 | splicing factor 3b, subunit 2, 145kDa | -0.0362258 |
| POTEF | POTE ankyrin domain family, member F | -0.0361747 |
| NOP58 | NOP58 ribonucleoprotein | -0.0361594 |
| RPLP1 | ribosomal protein, large, P1 | -0.0361467 |
| PRKDC | protein kinase, DNA-activated, catalytic polypeptide | -0.0360352 |
| MDK | midkine (neurite growth-promoting factor 2) | -0.0359683 |
| SMC4 | structural maintenance of chromosomes 4 | -0.0356662 |
| YBX1 | Y box binding protein 1 | -0.0352776 |
| RPL35A | ribosomal protein L35a | -0.0338635 |
| EEF2 | eukaryotic translation elongation factor 2 | -0.0330068 |
| DEK | DEK proto-oncogene | -0.032799 |
| RPS27A | ribosomal protein S27a | -0.0326724 |
| HMGB2 | high mobility group box 2 | -0.0325559 |
| CAP1 | CAP, adenylate cyclase-associated protein 1 (yeast) | -0.0323976 |
| KIF4A | kinesin family member 4A | -0.0323131 |
| NUSAP1 | nucleolar and spindle associated protein 1 | -0.0322144 |
| EMP1 | epithelial membrane protein 1 | -0.0319456 |
| PDIA6 | protein disulfide isomerase family A, member 6 | -0.0317386 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | -0.0316285 |
| PTGES3 | prostaglandin E synthase 3 (cytosolic) | -0.0312179 |
| PNISR | PNN-interacting serine/arginine-rich protein | -0.0307282 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | -0.0303798 |
| MARCKS | myristoylated alanine-rich protein kinase C substrate | -0.0303006 |
| TSC22D2 | TSC22 domain family, member 2 | -0.0302979 |
| SRPK2 | SRSF protein kinase 2 | -0.0299626 |
| SRP72 | signal recognition particle 72kDa | -0.0298186 |
| ENAH | enabled homolog (Drosophila) | -0.0293051 |
| CKAP5 | cytoskeleton associated protein 5 | -0.0292341 |
| H1-0 | H1.0 linker histone | -0.0292242 |
| ANKRD11 | ankyrin repeat domain 11 | -0.0292199 |
| KMT2C | lysine (K)-specific methyltransferase 2C | -0.0291511 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | -0.0289266 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.0288016 |
| IGF1R | insulin-like growth factor 1 receptor | -0.0284016 |
| ERC2 | ELKS/RAB6-interacting/CAST family member 2 | -0.0279828 |
| SNX6 | sorting nexin 6 | -0.027953 |
| NFKBIA | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha | -0.0274245 |
| RPL19 | ribosomal protein L19 | -0.0273855 |
| DDX56 | DEAD (Asp-Glu-Ala-Asp) box helicase 56 | -0.0269835 |
| CANX | calnexin | -0.0269682 |
| ENO1 | enolase 1, (alpha) | -0.0269488 |
