| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | (R)-Verapamil (hydrochloride) perturbation in PANC-1 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the (R)-Verapamil (hydrochloride)_PANC-1 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.1825 |
| RPS16 | ribosomal protein S16 | 0.0790925 |
| JMJD1C | jumonji domain containing 1C | 0.0782133 |
| SFTPA2 | surfactant protein A2 | 0.0700662 |
| TBC1D8 | TBC1 domain family, member 8 (with GRAM domain) | 0.0687677 |
| TXNRD1 | thioredoxin reductase 1 | 0.0618435 |
| MORF4L2 | mortality factor 4 like 2 | 0.0575948 |
| WWTR1 | WW domain containing transcription regulator 1 | 0.0575238 |
| MT2A | metallothionein 2A | 0.0550172 |
| RPS12 | ribosomal protein S12 | 0.0521824 |
| RPS3 | ribosomal protein S3 | 0.0508723 |
| RPS4X | ribosomal protein S4, X-linked | 0.0501924 |
| ARRDC3 | arrestin domain containing 3 | 0.0499487 |
| STAT3 | signal transducer and activator of transcription 3 (acute-phase response factor) | 0.0498204 |
| SQSTM1 | sequestosome 1 | 0.048677 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.0486703 |
| SEMA4B | sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4B | 0.0483609 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.0475707 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.0473202 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | 0.0469291 |
| MKI67 | marker of proliferation Ki-67 | 0.0461371 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | 0.045809 |
| APP | amyloid beta (A4) precursor protein | 0.044233 |
| TM4SF1 | transmembrane 4 L six family member 1 | 0.0436639 |
| ANGPTL4 | angiopoietin-like 4 | 0.0429712 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0427378 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | 0.04254 |
| ELL2 | elongation factor, RNA polymerase II, 2 | 0.0422748 |
| DGKD | diacylglycerol kinase, delta 130kDa | 0.041417 |
| PRRC2C | proline-rich coiled-coil 2C | 0.0408272 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | 0.0395375 |
| SUPT5H | suppressor of Ty 5 homolog (S. cerevisiae) | 0.0373926 |
| AFDN | afadin, adherens junction formation factor | 0.0363318 |
| RPS8 | ribosomal protein S8 | 0.0360314 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0358301 |
| ITGAV | integrin, alpha V | 0.0357942 |
| SEPTIN9 | septin 9 | 0.0355781 |
| VMP1 | vacuole membrane protein 1 | 0.0353098 |
| RPL37A | ribosomal protein L37a | 0.0345518 |
| BCL2L1 | BCL2-like 1 | 0.0344466 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0340301 |
| NFE2L2 | nuclear factor, erythroid 2-like 2 | 0.0338868 |
| JAK1 | Janus kinase 1 | 0.0331878 |
| KLF6 | Kruppel-like factor 6 | 0.0328778 |
| EIF1 | eukaryotic translation initiation factor 1 | 0.0327637 |
| THOC2 | THO complex 2 | 0.032463 |
| TMEM41B | transmembrane protein 41B | 0.0320913 |
| AHNAK2 | AHNAK nucleoprotein 2 | 0.0312042 |
| RACK1 | receptor for activated C kinase 1 | 0.0309617 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | 0.0301142 |
| SMYD3 | SET and MYND domain containing 3 | 0.0299363 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | 0.029586 |
| VCL | vinculin | 0.0293644 |
| RAB31 | RAB31, member RAS oncogene family | 0.0289398 |
| ARHGAP29 | Rho GTPase activating protein 29 | 0.0288481 |
| GCNT2 | glucosaminyl (N-acetyl) transferase 2, I-branching enzyme (I blood group) | 0.0285197 |
| ASPH | aspartate beta-hydroxylase | 0.028471 |
| RPL23 | ribosomal protein L23 | 0.0283729 |
| FHL2 | four and a half LIM domains 2 | 0.0282189 |
| HMOX1 | heme oxygenase 1 | 0.0279901 |
| BAIAP2L1 | BAI1-associated protein 2-like 1 | 0.0279866 |
| PRKDC | protein kinase, DNA-activated, catalytic polypeptide | 0.027899 |
| PTP4A2 | protein tyrosine phosphatase type IVA, member 2 | 0.0277953 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0276657 |
| FLNB | filamin B, beta | 0.0276397 |
| SLC7A11 | solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 | 0.0275505 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | 0.0275273 |
| ARID1A | AT rich interactive domain 1A (SWI-like) | 0.0269623 |
| WSB1 | WD repeat and SOCS box containing 1 | 0.0268444 |
| SPRED2 | sprouty-related, EVH1 domain containing 2 | 0.026757 |
| DNMBP | dynamin binding protein | 0.0265837 |
| ACTR3 | ARP3 actin-related protein 3 homolog (yeast) | 0.0265695 |
| YWHAG | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma | 0.0264772 |
| ATF6 | activating transcription factor 6 | 0.0263484 |
| B2M | beta-2-microglobulin | 0.0261313 |
| ANKRD11 | ankyrin repeat domain 11 | 0.0259264 |
| KTN1 | kinectin 1 (kinesin receptor) | 0.0255103 |
| YBX1 | Y box binding protein 1 | 0.0252079 |
| KLF7 | Kruppel-like factor 7 (ubiquitous) | 0.0251135 |
| SERINC1 | serine incorporator 1 | 0.0248117 |
| YWHAQ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta | 0.0246912 |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) | 0.024685 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | 0.0246548 |
| IRAK2 | interleukin-1 receptor-associated kinase 2 | 0.0245156 |
| LOC102724023 | ES1 protein homolog, mitochondrial | 0.024064 |
| BIRC2 | baculoviral IAP repeat containing 2 | 0.0237385 |
| MAPK8 | mitogen-activated protein kinase 8 | 0.0234274 |
| EIF4G3 | eukaryotic translation initiation factor 4 gamma, 3 | 0.0233109 |
| KIF5B | kinesin family member 5B | 0.0231822 |
| RPL26 | ribosomal protein L26 | 0.0228766 |
| SATB2 | SATB homeobox 2 | 0.0226615 |
| LUC7L3 | LUC7-like 3 (S. cerevisiae) | 0.0226231 |
| ATP13A3 | ATPase type 13A3 | 0.0226167 |
| PPP6R3 | protein phosphatase 6, regulatory subunit 3 | 0.022259 |
| SSH1 | slingshot protein phosphatase 1 | 0.022242 |
| NIPBL | Nipped-B homolog (Drosophila) | 0.0222225 |
| FUS | FUS RNA binding protein | 0.0221645 |
| SET | SET nuclear proto-oncogene | 0.0219477 |
| ANXA2 | annexin A2 | 0.0218236 |
| ITPRID2 | ITPR interacting domain containing 2 | 0.0217618 |
| Symbol | Name | Standardized Value |
|---|---|---|
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.191235 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | -0.159787 |
| AHNAK | AHNAK nucleoprotein | -0.147372 |
| VIM | vimentin | -0.128805 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | -0.119521 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0995478 |
| HSPG2 | heparan sulfate proteoglycan 2 | -0.0956056 |
| THSD4 | thrombospondin, type I, domain containing 4 | -0.0888513 |
| SLC35F3 | solute carrier family 35, member F3 | -0.0819534 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | -0.0730042 |
| TRIO | trio Rho guanine nucleotide exchange factor | -0.0634704 |
| TANC2 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 | -0.0634448 |
| HIVEP3 | human immunodeficiency virus type I enhancer binding protein 3 | -0.05992 |
| AKT2 | v-akt murine thymoma viral oncogene homolog 2 | -0.0592163 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0570857 |
| TNS3 | tensin 3 | -0.0514111 |
| KCNQ5 | potassium channel, voltage gated KQT-like subfamily Q, member 5 | -0.0479301 |
| ATG7 | autophagy related 7 | -0.0478612 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0476071 |
| CTSD | cathepsin D | -0.0470467 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.0468736 |
| EGFR | epidermal growth factor receptor | -0.0453848 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | -0.0447973 |
| DST | dystonin | -0.0437386 |
| RNF220 | ring finger protein 220 | -0.0421099 |
| UACA | uveal autoantigen with coiled-coil domains and ankyrin repeats | -0.0418145 |
| ZCCHC7 | zinc finger, CCHC domain containing 7 | -0.0414913 |
| DIAPH2 | diaphanous-related formin 2 | -0.0413335 |
| EGR1 | early growth response 1 | -0.0396592 |
| MACF1 | microtubule-actin crosslinking factor 1 | -0.0395332 |
| SDK1 | sidekick cell adhesion molecule 1 | -0.0385177 |
| MYOF | myoferlin | -0.0371134 |
| PTMA | prothymosin, alpha | -0.0369121 |
| HMGA2 | high mobility group AT-hook 2 | -0.0368655 |
| EEPD1 | endonuclease/exonuclease/phosphatase family domain containing 1 | -0.0361013 |
| NHSL1 | NHS-like 1 | -0.0351179 |
| CANX | calnexin | -0.0338058 |
| HMGA1 | high mobility group AT-hook 1 | -0.0332886 |
| POTEF | POTE ankyrin domain family, member F | -0.0332262 |
| PFN1 | profilin 1 | -0.0304688 |
| MAP1B | microtubule-associated protein 1B | -0.0301234 |
| MTHFD1L | methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1-like | -0.0289397 |
| H1-0 | H1.0 linker histone | -0.0284935 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0279987 |
| ZNF407 | zinc finger protein 407 | -0.026944 |
| EXOC4 | exocyst complex component 4 | -0.0263931 |
| ACTG1 | actin gamma 1 | -0.0255507 |
| PKM | pyruvate kinase, muscle | -0.0250617 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.0240587 |
| UAP1 | UDP-N-acetylglucosamine pyrophosphorylase 1 | -0.0238481 |
| MSN | moesin | -0.0238243 |
| EIF4G2 | eukaryotic translation initiation factor 4 gamma, 2 | -0.0235915 |
| EHBP1 | EH domain binding protein 1 | -0.0227897 |
| KRT8 | keratin 8, type II | -0.0227722 |
| PTPN14 | protein tyrosine phosphatase, non-receptor type 14 | -0.0226119 |
| PGK1 | phosphoglycerate kinase 1 | -0.0225461 |
| NEK10 | NIMA-related kinase 10 | -0.0223024 |
| ATP2A2 | ATPase, Ca++ transporting, cardiac muscle, slow twitch 2 | -0.0214849 |
| SRRM2 | serine/arginine repetitive matrix 2 | -0.0206497 |
| HM13 | histocompatibility (minor) 13 | -0.02058 |
| SHANK2 | SH3 and multiple ankyrin repeat domains 2 | -0.0205766 |
| IGF1R | insulin-like growth factor 1 receptor | -0.0205423 |
| PSMC4 | proteasome (prosome, macropain) 26S subunit, ATPase, 4 | -0.0204042 |
| CD109 | CD109 molecule | -0.0198956 |
| DNAH5 | dynein, axonemal, heavy chain 5 | -0.0195649 |
| ZNF780B | zinc finger protein 780B | -0.019467 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0194346 |
| CMIP | c-Maf inducing protein | -0.0191727 |
| PTK2 | protein tyrosine kinase 2 | -0.0190617 |
| GRIN2A | glutamate receptor, ionotropic, N-methyl D-aspartate 2A | -0.0189 |
| SUPT3H | suppressor of Ty 3 homolog (S. cerevisiae) | -0.0186228 |
| PRG2 | proteoglycan 2, bone marrow (natural killer cell activator, eosinophil granule major basic protein) | -0.0180977 |
| ST3GAL3 | ST3 beta-galactoside alpha-2,3-sialyltransferase 3 | -0.0180819 |
| MTCL1 | microtubule crosslinking factor 1 | -0.0176593 |
| MYO10 | myosin X | -0.0174621 |
| TAPBP | TAP binding protein (tapasin) | -0.0173788 |
| SBF2 | SET binding factor 2 | -0.0171278 |
| SETX | senataxin | -0.0170404 |
| FOSL1 | FOS-like antigen 1 | -0.0170373 |
| ANTXR1 | anthrax toxin receptor 1 | -0.0169992 |
| PDIA5 | protein disulfide isomerase family A, member 5 | -0.016795 |
| MCL1 | myeloid cell leukemia 1 | -0.0167276 |
| RAB7A | RAB7A, member RAS oncogene family | -0.0166666 |
| RASAL2 | RAS protein activator like 2 | -0.0166651 |
| FRMD4A | FERM domain containing 4A | -0.0164596 |
| PRKCA | protein kinase C, alpha | -0.0162255 |
| SPDYA | speedy/RINGO cell cycle regulator family member A | -0.0161665 |
| COL18A1 | collagen, type XVIII, alpha 1 | -0.0160999 |
| AFAP1 | actin filament associated protein 1 | -0.016032 |
| L1CAM | L1 cell adhesion molecule | -0.0160268 |
| PPARG | peroxisome proliferator-activated receptor gamma | -0.0159957 |
| PDIA6 | protein disulfide isomerase family A, member 6 | -0.0159167 |
| ARCN1 | archain 1 | -0.0158959 |
| WASF2 | WAS protein family, member 2 | -0.0158791 |
| ATP5F1B | ATP synthase F1 subunit beta | -0.0158579 |
| CDK6 | cyclin-dependent kinase 6 | -0.0158138 |
| ZNF546 | zinc finger protein 546 | -0.0157296 |
| IBTK | inhibitor of Bruton agammaglobulinemia tyrosine kinase | -0.0156476 |
| S100A6 | S100 calcium binding protein A6 | -0.0154527 |
| ZDHHC14 | zinc finger, DHHC-type containing 14 | -0.0154437 |
