| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | (R)-Verapamil (hydrochloride) perturbation in RKO cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the (R)-Verapamil (hydrochloride)_RKO drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| FLNB | filamin B, beta | 0.104814 |
| ELL2 | elongation factor, RNA polymerase II, 2 | 0.0940838 |
| ZEB1 | zinc finger E-box binding homeobox 1 | 0.0926252 |
| RPS3 | ribosomal protein S3 | 0.0904985 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.0886492 |
| RPS12 | ribosomal protein S12 | 0.0740198 |
| RPS2 | ribosomal protein S2 | 0.0617496 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.0599469 |
| SET | SET nuclear proto-oncogene | 0.0599406 |
| STC1 | stanniocalcin 1 | 0.0582389 |
| C2CD2 | C2 calcium-dependent domain containing 2 | 0.0514002 |
| NDRG1 | N-myc downstream regulated 1 | 0.0507525 |
| ARHGAP22 | Rho GTPase activating protein 22 | 0.0503335 |
| RACK1 | receptor for activated C kinase 1 | 0.0486925 |
| FRMD4A | FERM domain containing 4A | 0.0478583 |
| LDHA | lactate dehydrogenase A | 0.0456665 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.045643 |
| STK4 | serine/threonine kinase 4 | 0.045208 |
| JUN | jun proto-oncogene | 0.0425615 |
| PSMD2 | proteasome (prosome, macropain) 26S subunit, non-ATPase, 2 | 0.042458 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | 0.0399569 |
| LAMB3 | laminin, beta 3 | 0.0394417 |
| SPRED2 | sprouty-related, EVH1 domain containing 2 | 0.0392397 |
| JMJD1C | jumonji domain containing 1C | 0.0390286 |
| SGMS2 | sphingomyelin synthase 2 | 0.0390186 |
| ACTN1 | actinin, alpha 1 | 0.0389413 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | 0.0372175 |
| NAV3 | neuron navigator 3 | 0.0366924 |
| EIF3A | eukaryotic translation initiation factor 3, subunit A | 0.0364557 |
| CAPN2 | calpain 2, (m/II) large subunit | 0.0362824 |
| NUP58 | nucleoporin 58 | 0.0353711 |
| NACA | nascent polypeptide-associated complex alpha subunit | 0.0352892 |
| RPS4X | ribosomal protein S4, X-linked | 0.0349612 |
| GPBP1 | GC-rich promoter binding protein 1 | 0.0345858 |
| ADTRP | androgen-dependent TFPI-regulating protein | 0.0333642 |
| APP | amyloid beta (A4) precursor protein | 0.0333331 |
| RASA2 | RAS p21 protein activator 2 | 0.0326365 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | 0.0322422 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0310642 |
| FBXO11 | F-box protein 11 | 0.0305898 |
| IGF2BP2 | insulin-like growth factor 2 mRNA binding protein 2 | 0.030584 |
| CYP51A1 | cytochrome P450, family 51, subfamily A, polypeptide 1 | 0.0298114 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | 0.0297184 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.0293374 |
| TPT1 | tumor protein, translationally-controlled 1 | 0.0290527 |
| CORO1C | coronin, actin binding protein, 1C | 0.0289111 |
| YWHAG | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma | 0.0279784 |
| TMF1 | TATA element modulatory factor 1 | 0.0269973 |
| TEX10 | testis expressed 10 | 0.0268043 |
| PPP2R2A | protein phosphatase 2, regulatory subunit B, alpha | 0.0265183 |
| RSL1D1 | ribosomal L1 domain containing 1 | 0.0262929 |
| DNAJC5 | DnaJ (Hsp40) homolog, subfamily C, member 5 | 0.0260418 |
| IARS1 | isoleucyl-tRNA synthetase 1 | 0.0259899 |
| CALR | calreticulin | 0.0252595 |
| CHD1 | chromodomain helicase DNA binding protein 1 | 0.0251427 |
| KIF5B | kinesin family member 5B | 0.0251351 |
| CSNK1A1 | casein kinase 1, alpha 1 | 0.0251329 |
| IFI6 | interferon, alpha-inducible protein 6 | 0.0250355 |
| HSPA8 | heat shock 70kDa protein 8 | 0.024718 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0246415 |
| PHC2 | polyhomeotic homolog 2 (Drosophila) | 0.02463 |
| KMT2E | lysine (K)-specific methyltransferase 2E | 0.0244337 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0239647 |
| EFNB2 | ephrin-B2 | 0.0237742 |
| RLF | rearranged L-myc fusion | 0.0236704 |
| AFDN | afadin, adherens junction formation factor | 0.0236643 |
| PDIA6 | protein disulfide isomerase family A, member 6 | 0.0236148 |
| PTPN1 | protein tyrosine phosphatase, non-receptor type 1 | 0.0234433 |
| PRRC2C | proline-rich coiled-coil 2C | 0.0232658 |
| MCL1 | myeloid cell leukemia 1 | 0.0230885 |
| PSME4 | proteasome (prosome, macropain) activator subunit 4 | 0.0230543 |
| ATP13A3 | ATPase type 13A3 | 0.0228811 |
| FN1 | fibronectin 1 | 0.0226675 |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) | 0.022495 |
| SPAG9 | sperm associated antigen 9 | 0.0223611 |
| MAST4 | microtubule associated serine/threonine kinase family member 4 | 0.022332 |
| WAC | WW domain containing adaptor with coiled-coil | 0.0222982 |
| CHIC2 | cysteine-rich hydrophobic domain 2 | 0.0222798 |
| FHL2 | four and a half LIM domains 2 | 0.0220241 |
| GNL3 | guanine nucleotide binding protein-like 3 (nucleolar) | 0.021952 |
| SCAF8 | SR-related CTD-associated factor 8 | 0.0218333 |
| CDC73 | cell division cycle 73 | 0.0216521 |
| KDM3A | lysine (K)-specific demethylase 3A | 0.0212438 |
| G3BP2 | GTPase activating protein (SH3 domain) binding protein 2 | 0.0211093 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | 0.0211092 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | 0.0211007 |
| ZNF146 | zinc finger protein 146 | 0.0206818 |
| ANXA5 | annexin A5 | 0.0206798 |
| MTDH | metadherin | 0.0204506 |
| GFPT2 | glutamine-fructose-6-phosphate transaminase 2 | 0.0204499 |
| EFR3A | EFR3 homolog A (S. cerevisiae) | 0.0203856 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | 0.020275 |
| RPS17 | ribosomal protein S17 | 0.020249 |
| BHLHE40 | basic helix-loop-helix family, member e40 | 0.0201622 |
| S100A10 | S100 calcium binding protein A10 | 0.0201428 |
| SMURF2 | SMAD specific E3 ubiquitin protein ligase 2 | 0.0200928 |
| PFDN2 | prefoldin subunit 2 | 0.020076 |
| EXT1 | exostosin glycosyltransferase 1 | 0.0200465 |
| OSBPL8 | oxysterol binding protein-like 8 | 0.0198044 |
| HSPA9 | heat shock 70kDa protein 9 (mortalin) | 0.0194223 |
| Symbol | Name | Standardized Value |
|---|---|---|
| ACTG1 | actin gamma 1 | -0.101714 |
| MT2A | metallothionein 2A | -0.0636011 |
| RPL35A | ribosomal protein L35a | -0.0615381 |
| RPLP1 | ribosomal protein, large, P1 | -0.0613105 |
| PFN1 | profilin 1 | -0.061019 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0583946 |
| RPLP2 | ribosomal protein, large, P2 | -0.0546455 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0512173 |
| RPS6 | ribosomal protein S6 | -0.0501979 |
| DIAPH3 | diaphanous-related formin 3 | -0.0478132 |
| DLC1 | DLC1 Rho GTPase activating protein | -0.0477473 |
| RPS20 | ribosomal protein S20 | -0.0417739 |
| RPL7 | ribosomal protein L7 | -0.0412155 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0410201 |
| RPL7A | ribosomal protein L7a | -0.040279 |
| PBX3 | pre-B-cell leukemia homeobox 3 | -0.037991 |
| RPL30 | ribosomal protein L30 | -0.0379776 |
| EEF1D | eukaryotic translation elongation factor 1 delta (guanine nucleotide exchange protein) | -0.0369821 |
| POTEF | POTE ankyrin domain family, member F | -0.0358153 |
| NF1 | neurofibromin 1 | -0.0356667 |
| PRRC2B | proline-rich coiled-coil 2B | -0.035522 |
| RPLP0 | ribosomal protein, large, P0 | -0.0342744 |
| LDHB | lactate dehydrogenase B | -0.0339352 |
| S100A2 | S100 calcium binding protein A2 | -0.0337596 |
| RPS13 | ribosomal protein S13 | -0.0336743 |
| VPS13B | vacuolar protein sorting 13 homolog B (yeast) | -0.0336096 |
| RPS21 | ribosomal protein S21 | -0.0335072 |
| ADAMTS6 | ADAM metallopeptidase with thrombospondin type 1 motif, 6 | -0.0334021 |
| NAV2 | neuron navigator 2 | -0.0333309 |
| HMGA2 | high mobility group AT-hook 2 | -0.0330384 |
| EXOC4 | exocyst complex component 4 | -0.0326832 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0325238 |
| ATP5F1B | ATP synthase F1 subunit beta | -0.0321499 |
| TEAD1 | TEA domain family member 1 (SV40 transcriptional enhancer factor) | -0.0308349 |
| GNAS | GNAS complex locus | -0.0305812 |
| FAF1 | Fas (TNFRSF6) associated factor 1 | -0.030264 |
| FOSL1 | FOS-like antigen 1 | -0.0301029 |
| SBF2 | SET binding factor 2 | -0.0289278 |
| RPL10A | ribosomal protein L10a | -0.0288668 |
| RPL28 | ribosomal protein L28 | -0.0287501 |
| CALD1 | caldesmon 1 | -0.0287279 |
| SUPT3H | suppressor of Ty 3 homolog (S. cerevisiae) | -0.0283855 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | -0.0280703 |
| MON2 | MON2 homolog (S. cerevisiae) | -0.0280244 |
| TMSB10 | thymosin beta 10 | -0.0278554 |
| RAB3IP | RAB3A interacting protein | -0.0275541 |
| NABP1 | nucleic acid binding protein 1 | -0.0271661 |
| TAS2R14 | taste receptor, type 2, member 14 | -0.0263658 |
| RPL9 | ribosomal protein L9 | -0.0259215 |
| RPS16 | ribosomal protein S16 | -0.0257942 |
| ASAP1 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 | -0.025513 |
| TBC1D5 | TBC1 domain family, member 5 | -0.0247464 |
| DEK | DEK proto-oncogene | -0.024459 |
| DENND1A | DENN/MADD domain containing 1A | -0.0241943 |
| RPL27A | ribosomal protein L27a | -0.0238318 |
| RHOA | ras homolog family member A | -0.0237738 |
| UAP1 | UDP-N-acetylglucosamine pyrophosphorylase 1 | -0.0232315 |
| LPP | LIM domain containing preferred translocation partner in lipoma | -0.0230214 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.0230056 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.0228859 |
| SAMD4A | sterile alpha motif domain containing 4A | -0.0228735 |
| RPL19 | ribosomal protein L19 | -0.0226868 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | -0.0226778 |
| PPDPF | pancreatic progenitor cell differentiation and proliferation factor | -0.022592 |
| NR6A1 | nuclear receptor subfamily 6, group A, member 1 | -0.0224387 |
| ARID4B | AT rich interactive domain 4B (RBP1-like) | -0.0223212 |
| RPL38 | ribosomal protein L38 | -0.0220108 |
| FRMD6 | FERM domain containing 6 | -0.0217055 |
| SMC4 | structural maintenance of chromosomes 4 | -0.0215062 |
| TUBA1C | tubulin, alpha 1c | -0.0214901 |
| RPS19 | ribosomal protein S19 | -0.0212038 |
| ARPC2 | actin related protein 2/3 complex, subunit 2, 34kDa | -0.0211469 |
| AHI1 | Abelson helper integration site 1 | -0.0210024 |
| MED27 | mediator complex subunit 27 | -0.0209835 |
| AEBP2 | AE binding protein 2 | -0.0209812 |
| RTN4 | reticulon 4 | -0.0206859 |
| GART | phosphoribosylglycinamide formyltransferase, phosphoribosylglycinamide synthetase, phosphoribosylaminoimidazole synthetase | -0.0206778 |
| G2E3 | G2/M-phase specific E3 ubiquitin protein ligase | -0.020556 |
| RPL13A | ribosomal protein L13a | -0.0201668 |
| ZBTB43 | zinc finger and BTB domain containing 43 | -0.0201426 |
| TUBA1B | tubulin, alpha 1b | -0.0197531 |
| EEF1G | eukaryotic translation elongation factor 1 gamma | -0.0196563 |
| N4BP2L2 | NEDD4 binding protein 2-like 2 | -0.0196484 |
| MKLN1 | muskelin 1, intracellular mediator containing kelch motifs | -0.0195171 |
| COL27A1 | collagen, type XXVII, alpha 1 | -0.0193366 |
| RPL8 | ribosomal protein L8 | -0.0188966 |
| MT1X | metallothionein 1X | -0.0188416 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | -0.0188172 |
| ARID2 | AT rich interactive domain 2 (ARID, RFX-like) | -0.0187021 |
| SRRM2 | serine/arginine repetitive matrix 2 | -0.0187016 |
| UBXN4 | UBX domain protein 4 | -0.0185153 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.0184762 |
| PTK2 | protein tyrosine kinase 2 | -0.0182436 |
| FNIP1 | folliculin interacting protein 1 | -0.0182135 |
| ASNS | asparagine synthetase (glutamine-hydrolyzing) | -0.0181443 |
| RPL34 | ribosomal protein L34 | -0.0181348 |
| RPL21 | ribosomal protein L21 | -0.0179134 |
| RAB3GAP1 | RAB3 GTPase activating protein subunit 1 (catalytic) | -0.0178664 |
| SND1 | staphylococcal nuclease and tudor domain containing 1 | -0.0177113 |
| KIF20B | kinesin family member 20B | -0.0176402 |
