| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | (R)-Verapamil (hydrochloride) perturbation in RPMI-7951 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the (R)-Verapamil (hydrochloride)_RPMI-7951 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| IGFBP3 | insulin-like growth factor binding protein 3 | 0.0786742 |
| MT2A | metallothionein 2A | 0.0739448 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.0456861 |
| ANGPTL4 | angiopoietin-like 4 | 0.0451415 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0416439 |
| RPS12 | ribosomal protein S12 | 0.0357488 |
| RPS3 | ribosomal protein S3 | 0.0278938 |
| RPL36 | ribosomal protein L36 | 0.0274155 |
| RPL26 | ribosomal protein L26 | 0.0269187 |
| RPS8 | ribosomal protein S8 | 0.026891 |
| RPL23 | ribosomal protein L23 | 0.0266403 |
| WWTR1 | WW domain containing transcription regulator 1 | 0.0264885 |
| RPS17 | ribosomal protein S17 | 0.0264764 |
| TPT1 | tumor protein, translationally-controlled 1 | 0.0236586 |
| SVIL | supervillin | 0.0229308 |
| PRRC2C | proline-rich coiled-coil 2C | 0.0220143 |
| HMGA2 | high mobility group AT-hook 2 | 0.0207063 |
| FLNB | filamin B, beta | 0.0206575 |
| RPL37A | ribosomal protein L37a | 0.0188962 |
| IFI6 | interferon, alpha-inducible protein 6 | 0.0183009 |
| IGF2 | insulin-like growth factor 2 | 0.0174296 |
| PLEKHA4 | pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 4 | 0.0174044 |
| EIF3A | eukaryotic translation initiation factor 3, subunit A | 0.0172639 |
| FAT1 | FAT atypical cadherin 1 | 0.0168272 |
| IFI44L | interferon-induced protein 44-like | 0.016243 |
| EIF1 | eukaryotic translation initiation factor 1 | 0.0157062 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0156275 |
| RPL32 | ribosomal protein L32 | 0.0150533 |
| KPNA4 | karyopherin alpha 4 (importin alpha 3) | 0.0149199 |
| ARRDC3 | arrestin domain containing 3 | 0.014879 |
| NUMBL | numb homolog (Drosophila)-like | 0.0143659 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0140419 |
| RPL5 | ribosomal protein L5 | 0.0139123 |
| RPS4X | ribosomal protein S4, X-linked | 0.0139013 |
| IFIT1 | interferon-induced protein with tetratricopeptide repeats 1 | 0.0138732 |
| SLC39A14 | solute carrier family 39 (zinc transporter), member 14 | 0.0137829 |
| PTPRD | protein tyrosine phosphatase, receptor type, D | 0.0137065 |
| SLK | STE20-like kinase | 0.0133554 |
| AFDN | afadin, adherens junction formation factor | 0.0130995 |
| RPS27 | ribosomal protein S27 | 0.0128441 |
| SMAD3 | SMAD family member 3 | 0.0128212 |
| DLGAP4 | discs, large (Drosophila) homolog-associated protein 4 | 0.0123407 |
| RPL36A | ribosomal protein L36a | 0.012122 |
| RPS6 | ribosomal protein S6 | 0.0119936 |
| RPS2 | ribosomal protein S2 | 0.011828 |
| SQSTM1 | sequestosome 1 | 0.0118197 |
| MT1E | metallothionein 1E | 0.0117972 |
| SEPTIN9 | septin 9 | 0.0115072 |
| YWHAG | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma | 0.0114985 |
| PHF14 | PHD finger protein 14 | 0.0114954 |
| CEP290 | centrosomal protein 290kDa | 0.0114645 |
| NRIP1 | nuclear receptor interacting protein 1 | 0.0114551 |
| SCAPER | S-phase cyclin A-associated protein in the ER | 0.0112608 |
| CTNNB1 | catenin (cadherin-associated protein), beta 1, 88kDa | 0.0111735 |
| ITSN2 | intersectin 2 | 0.0111644 |
| SMYD3 | SET and MYND domain containing 3 | 0.0111146 |
| HELZ2 | helicase with zinc finger 2, transcriptional coactivator | 0.0110453 |
| CELF1 | CUGBP, Elav-like family member 1 | 0.0109773 |
| SPAG9 | sperm associated antigen 9 | 0.0109638 |
| CCL5 | chemokine (C-C motif) ligand 5 | 0.010727 |
| H2AC6 | H2A clustered histone 6 | 0.0107239 |
| NFE2L1 | nuclear factor, erythroid 2-like 1 | 0.0106123 |
| MMP14 | matrix metallopeptidase 14 (membrane-inserted) | 0.0105918 |
| SEMA4B | sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4B | 0.0105719 |
| PHC2 | polyhomeotic homolog 2 (Drosophila) | 0.0105666 |
| RACK1 | receptor for activated C kinase 1 | 0.0104792 |
| PARP4 | poly (ADP-ribose) polymerase family, member 4 | 0.0103602 |
| IGF2BP2 | insulin-like growth factor 2 mRNA binding protein 2 | 0.0102316 |
| PMP22 | peripheral myelin protein 22 | 0.0101379 |
| KLF6 | Kruppel-like factor 6 | 0.0101121 |
| WNT9A | wingless-type MMTV integration site family, member 9A | 0.0101036 |
| SPSB1 | splA/ryanodine receptor domain and SOCS box containing 1 | 0.0100957 |
| RPS15 | ribosomal protein S15 | 0.0100271 |
| SOX9 | SRY (sex determining region Y)-box 9 | 0.00991422 |
| ZMIZ1 | zinc finger, MIZ-type containing 1 | 0.00989438 |
| RBFOX1 | RNA binding protein, fox-1 homolog (C. elegans) 1 | 0.00986191 |
| PLEC | plectin | 0.00971295 |
| EZR | ezrin | 0.00958792 |
| ZC3H12B | zinc finger CCCH-type containing 12B | 0.00948163 |
| SETBP1 | SET binding protein 1 | 0.00942695 |
| TNFRSF12A | tumor necrosis factor receptor superfamily, member 12A | 0.00939739 |
| CAMK2D | calcium/calmodulin-dependent protein kinase II delta | 0.00931958 |
| DHRS3 | dehydrogenase/reductase (SDR family) member 3 | 0.00931429 |
| DNAJB1 | DnaJ (Hsp40) homolog, subfamily B, member 1 | 0.00919112 |
| TSC22D1 | TSC22 domain family, member 1 | 0.00914579 |
| OXSR1 | oxidative stress responsive 1 | 0.00913714 |
| PPP2R2A | protein phosphatase 2, regulatory subunit B, alpha | 0.00909996 |
| RALGAPA2 | Ral GTPase activating protein, alpha subunit 2 (catalytic) | 0.00906477 |
| HNRNPDL | heterogeneous nuclear ribonucleoprotein D-like | 0.00898678 |
| PRELID2 | PRELI domain containing 2 | 0.00892929 |
| PRKN | parkin RBR E3 ubiquitin protein ligase | 0.00890807 |
| SLC25A37 | solute carrier family 25 (mitochondrial iron transporter), member 37 | 0.00883264 |
| EIF4H | eukaryotic translation initiation factor 4H | 0.00881112 |
| MBNL1 | muscleblind-like splicing regulator 1 | 0.00871755 |
| TRIM25 | tripartite motif containing 25 | 0.00870195 |
| APP | amyloid beta (A4) precursor protein | 0.00864425 |
| BCL2L1 | BCL2-like 1 | 0.00863377 |
| FBXL3 | F-box and leucine-rich repeat protein 3 | 0.00857316 |
| PRRC2B | proline-rich coiled-coil 2B | 0.00854709 |
| PLA2G4C | phospholipase A2, group IVC (cytosolic, calcium-independent) | 0.00837177 |
| Symbol | Name | Standardized Value |
|---|---|---|
| VIM | vimentin | -0.287928 |
| FN1 | fibronectin 1 | -0.226798 |
| COL1A2 | collagen, type I, alpha 2 | -0.173672 |
| TIMP3 | TIMP metallopeptidase inhibitor 3 | -0.137988 |
| COL1A1 | collagen, type I, alpha 1 | -0.119441 |
| POTEF | POTE ankyrin domain family, member F | -0.103887 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | -0.099849 |
| CDH13 | cadherin 13 | -0.0974156 |
| FNDC3B | fibronectin type III domain containing 3B | -0.0857722 |
| COL6A1 | collagen, type VI, alpha 1 | -0.0834074 |
| INHBA | inhibin, beta A | -0.0700486 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.06979 |
| COL6A2 | collagen, type VI, alpha 2 | -0.0682155 |
| B2M | beta-2-microglobulin | -0.0611908 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.0611786 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | -0.0595383 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0593323 |
| TPM4 | tropomyosin 4 | -0.0579783 |
| SPARC | secreted protein, acidic, cysteine-rich (osteonectin) | -0.0578868 |
| TMSB10 | thymosin beta 10 | -0.0548707 |
| GOLGA4 | golgin A4 | -0.0534596 |
| ZEB1 | zinc finger E-box binding homeobox 1 | -0.052595 |
| FRMD4A | FERM domain containing 4A | -0.0525501 |
| MMP12 | matrix metallopeptidase 12 | -0.052185 |
| PGK1 | phosphoglycerate kinase 1 | -0.0516868 |
| TPM1 | tropomyosin 1 (alpha) | -0.0512325 |
| RAB7A | RAB7A, member RAS oncogene family | -0.0494774 |
| TNS3 | tensin 3 | -0.0490133 |
| TENT5A | terminal nucleotidyltransferase 5A | -0.0465762 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | -0.0450892 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0444232 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.044174 |
| DLG1 | discs, large homolog 1 (Drosophila) | -0.0434853 |
| PTPRG | protein tyrosine phosphatase, receptor type, G | -0.0426056 |
| NAV1 | neuron navigator 1 | -0.0416856 |
| FTL | ferritin, light polypeptide | -0.0409939 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.0403157 |
| PTMA | prothymosin, alpha | -0.040184 |
| S100A6 | S100 calcium binding protein A6 | -0.0392501 |
| P4HA2 | prolyl 4-hydroxylase, alpha polypeptide II | -0.0383424 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | -0.0371172 |
| SETD5 | SET domain containing 5 | -0.0367064 |
| F3 | coagulation factor III (thromboplastin, tissue factor) | -0.0365842 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.0365756 |
| NRP1 | neuropilin 1 | -0.0365373 |
| MARCKS | myristoylated alanine-rich protein kinase C substrate | -0.0365042 |
| GLIS3 | GLIS family zinc finger 3 | -0.036236 |
| GNAS | GNAS complex locus | -0.03607 |
| CD109 | CD109 molecule | -0.035196 |
| ITGA1 | integrin, alpha 1 | -0.034797 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0343208 |
| DSTN | destrin (actin depolymerizing factor) | -0.0340108 |
| RRBP1 | ribosome binding protein 1 | -0.0336539 |
| CALD1 | caldesmon 1 | -0.0330278 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | -0.0329668 |
| MYH9 | myosin, heavy chain 9, non-muscle | -0.0327441 |
| ITGA11 | integrin, alpha 11 | -0.0323538 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | -0.0321117 |
| JARID2 | jumonji, AT rich interactive domain 2 | -0.0320445 |
| TNNC1 | troponin C type 1 (slow) | -0.0310716 |
| MMP2 | matrix metallopeptidase 2 | -0.0307173 |
| PKM | pyruvate kinase, muscle | -0.0305501 |
| VCAN | versican | -0.0301396 |
| NBAS | neuroblastoma amplified sequence | -0.0300552 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0298539 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | -0.029676 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0296739 |
| RAB1A | RAB1A, member RAS oncogene family | -0.0288837 |
| CTSB | cathepsin B | -0.0287744 |
| LPP | LIM domain containing preferred translocation partner in lipoma | -0.0286431 |
| RBMS3 | RNA binding motif, single stranded interacting protein 3 | -0.0286428 |
| APCDD1L | adenomatosis polyposis coli down-regulated 1-like | -0.0286363 |
| PAG1 | phosphoprotein membrane anchor with glycosphingolipid microdomains 1 | -0.0282067 |
| IQGAP1 | IQ motif containing GTPase activating protein 1 | -0.0275609 |
| BCAT1 | branched chain amino-acid transaminase 1, cytosolic | -0.0272354 |
| MEF2A | myocyte enhancer factor 2A | -0.0272036 |
| SEMA5A | sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5A | -0.0270086 |
| CAPZB | capping protein (actin filament) muscle Z-line, beta | -0.0270016 |
| ARL4C | ADP-ribosylation factor-like 4C | -0.0269969 |
| EML5 | echinoderm microtubule associated protein like 5 | -0.0267225 |
| ADAM12 | ADAM metallopeptidase domain 12 | -0.0267159 |
| FAM20C | family with sequence similarity 20, member C | -0.0266912 |
| ROBO1 | roundabout, axon guidance receptor, homolog 1 (Drosophila) | -0.0265883 |
| MSN | moesin | -0.0265323 |
| THBS1 | thrombospondin 1 | -0.0265172 |
| VCL | vinculin | -0.0264559 |
| TMEM178B | transmembrane protein 178B | -0.0259048 |
| CADM1 | cell adhesion molecule 1 | -0.0258835 |
| ITPR1 | inositol 1,4,5-trisphosphate receptor, type 1 | -0.0256813 |
| LOXL2 | lysyl oxidase-like 2 | -0.0256135 |
| STC1 | stanniocalcin 1 | -0.0254965 |
| LPAR1 | lysophosphatidic acid receptor 1 | -0.0251174 |
| SLC24A3 | solute carrier family 24 (sodium/potassium/calcium exchanger), member 3 | -0.0250709 |
| SERPINH1 | serpin peptidase inhibitor, clade H (heat shock protein 47), member 1, (collagen binding protein 1) | -0.0250608 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | -0.0249034 |
| TMEM263 | transmembrane protein 263 | -0.0246437 |
| HDLBP | high density lipoprotein binding protein | -0.0245923 |
| EXT1 | exostosin glycosyltransferase 1 | -0.0243589 |
| DIP2C | DIP2 disco-interacting protein 2 homolog C (Drosophila) | -0.024151 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | -0.0239506 |