| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | (R)-Verapamil (hydrochloride) perturbation in SHP-77 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the (R)-Verapamil (hydrochloride)_SHP-77 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| NR3C1 | nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) | 0.0622075 |
| SNAP25 | synaptosomal-associated protein, 25kDa | 0.0589984 |
| ASPH | aspartate beta-hydroxylase | 0.0455908 |
| AHR | aryl hydrocarbon receptor | 0.0437402 |
| FNDC3A | fibronectin type III domain containing 3A | 0.0414181 |
| SMOC1 | SPARC related modular calcium binding 1 | 0.0402033 |
| TTC19 | tetratricopeptide repeat domain 19 | 0.0305215 |
| DHRS3 | dehydrogenase/reductase (SDR family) member 3 | 0.0294648 |
| SIK2 | salt-inducible kinase 2 | 0.0291136 |
| SMAD3 | SMAD family member 3 | 0.0270151 |
| FLNB | filamin B, beta | 0.0268765 |
| RNASE12 | ribonuclease, RNase A family, 12 (non-active) | 0.0262714 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0260071 |
| CTNNB1 | catenin (cadherin-associated protein), beta 1, 88kDa | 0.0244713 |
| MSN | moesin | 0.0240861 |
| PCBP2 | poly(rC) binding protein 2 | 0.0232567 |
| MBNL1 | muscleblind-like splicing regulator 1 | 0.0226026 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | 0.0224721 |
| IRS2 | insulin receptor substrate 2 | 0.02167 |
| RUNX1 | runt-related transcription factor 1 | 0.0211717 |
| SLC38A2 | solute carrier family 38, member 2 | 0.0210926 |
| INHBA | inhibin, beta A | 0.0207645 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.020481 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.020468 |
| UBE2QL1 | ubiquitin-conjugating enzyme E2Q family-like 1 | 0.0192391 |
| PCM1 | pericentriolar material 1 | 0.0192365 |
| KMT2E | lysine (K)-specific methyltransferase 2E | 0.0190977 |
| ANKH | ANKH inorganic pyrophosphate transport regulator | 0.0186138 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | 0.0182675 |
| RPS4X | ribosomal protein S4, X-linked | 0.018065 |
| DUSP10 | dual specificity phosphatase 10 | 0.0178382 |
| EP400 | E1A binding protein p400 | 0.0177201 |
| LPP | LIM domain containing preferred translocation partner in lipoma | 0.0176686 |
| AOPEP | aminopeptidase O (putative) | 0.0171939 |
| BIRC6 | baculoviral IAP repeat containing 6 | 0.0167514 |
| TEAD1 | TEA domain family member 1 (SV40 transcriptional enhancer factor) | 0.016667 |
| ADARB1 | adenosine deaminase, RNA-specific, B1 | 0.0165637 |
| VEGFA | vascular endothelial growth factor A | 0.0165301 |
| HUWE1 | HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase | 0.0163318 |
| CTBP2 | C-terminal binding protein 2 | 0.0162572 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0161567 |
| ASCL1 | achaete-scute family bHLH transcription factor 1 | 0.0159976 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | 0.0159732 |
| RARB | retinoic acid receptor, beta | 0.0158308 |
| LRRTM4 | leucine rich repeat transmembrane neuronal 4 | 0.01581 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0157981 |
| MPRIP | myosin phosphatase Rho interacting protein | 0.0154113 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | 0.0151343 |
| HYOU1 | hypoxia up-regulated 1 | 0.0149604 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | 0.0147969 |
| ZFHX3 | zinc finger homeobox 3 | 0.0145524 |
| BTAF1 | BTAF1 RNA polymerase II, B-TFIID transcription factor-associated, 170kDa | 0.0145188 |
| EXT1 | exostosin glycosyltransferase 1 | 0.0144833 |
| DIDO1 | death inducer-obliterator 1 | 0.0144814 |
| EZR | ezrin | 0.014477 |
| NDRG1 | N-myc downstream regulated 1 | 0.0141364 |
| NEDD4L | neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase | 0.0140219 |
| PDK4 | pyruvate dehydrogenase kinase, isozyme 4 | 0.0138642 |
| KMT2D | lysine (K)-specific methyltransferase 2D | 0.0136969 |
| TOX3 | TOX high mobility group box family member 3 | 0.0136918 |
| TUFT1 | tuftelin 1 | 0.0136316 |
| ELF3 | E74-like factor 3 (ets domain transcription factor, epithelial-specific ) | 0.0136262 |
| PRKAR1A | protein kinase, cAMP-dependent, regulatory, type I, alpha | 0.0134462 |
| BDKRB2 | bradykinin receptor B2 | 0.0134329 |
| ANKRD36C | ankyrin repeat domain 36C | 0.0134199 |
| TIMP2 | TIMP metallopeptidase inhibitor 2 | 0.0133482 |
| TGFA | transforming growth factor, alpha | 0.0132627 |
| EHBP1 | EH domain binding protein 1 | 0.0132292 |
| POLE | polymerase (DNA directed), epsilon, catalytic subunit | 0.0131978 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0130484 |
| LOXL2 | lysyl oxidase-like 2 | 0.0129456 |
| CABIN1 | calcineurin binding protein 1 | 0.0128854 |
| UPF2 | UPF2 regulator of nonsense transcripts homolog (yeast) | 0.0128669 |
| DOCK5 | dedicator of cytokinesis 5 | 0.0128663 |
| BAZ1B | bromodomain adjacent to zinc finger domain, 1B | 0.0127901 |
| MYOF | myoferlin | 0.0126963 |
| KLF7 | Kruppel-like factor 7 (ubiquitous) | 0.0126126 |
| ADSS2 | adenylosuccinate synthase 2 | 0.0125966 |
| ARGLU1 | arginine and glutamate rich 1 | 0.0125278 |
| TNRC6C | trinucleotide repeat containing 6C | 0.0125127 |
| SVIL | supervillin | 0.0124555 |
| HSPH1 | heat shock 105kDa/110kDa protein 1 | 0.012438 |
| ABCC4 | ATP-binding cassette, sub-family C (CFTR/MRP), member 4 | 0.0121876 |
| TPP2 | tripeptidyl peptidase II | 0.0121847 |
| CDC42BPA | CDC42 binding protein kinase alpha (DMPK-like) | 0.0121219 |
| SQSTM1 | sequestosome 1 | 0.0120448 |
| SEPTIN9 | septin 9 | 0.0119856 |
| NR4A3 | nuclear receptor subfamily 4, group A, member 3 | 0.0119567 |
| TRA2B | transformer 2 beta homolog (Drosophila) | 0.0119449 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | 0.0119407 |
| FAM135A | family with sequence similarity 135, member A | 0.0118089 |
| NSUN6 | NOP2/Sun domain family, member 6 | 0.0117674 |
| ZZZ3 | zinc finger, ZZ-type containing 3 | 0.0117317 |
| LRP5 | low density lipoprotein receptor-related protein 5 | 0.0117293 |
| ARFGAP1 | ADP-ribosylation factor GTPase activating protein 1 | 0.0116473 |
| AHDC1 | AT hook, DNA binding motif, containing 1 | 0.011614 |
| GPCPD1 | glycerophosphocholine phosphodiesterase GDE1 homolog (S. cerevisiae) | 0.0115839 |
| IVNS1ABP | influenza virus NS1A binding protein | 0.011373 |
| DGKD | diacylglycerol kinase, delta 130kDa | 0.0113649 |
| MEF2D | myocyte enhancer factor 2D | 0.0113474 |
| Symbol | Name | Standardized Value |
|---|---|---|
| NALF1 | NALCN channel auxiliary factor 1 | -0.174094 |
| GPC6 | glypican 6 | -0.151472 |
| NRG1 | neuregulin 1 | -0.113851 |
| SNTG1 | syntrophin, gamma 1 | -0.104621 |
| PTMA | prothymosin, alpha | -0.0921646 |
| KCND2 | potassium channel, voltage gated Shal related subfamily D, member 2 | -0.0870394 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0863587 |
| ADARB2 | adenosine deaminase, RNA-specific, B2 (non-functional) | -0.0846453 |
| ENO1 | enolase 1, (alpha) | -0.0827086 |
| NKAIN2 | Na+/K+ transporting ATPase interacting 2 | -0.0823751 |
| RIMS2 | regulating synaptic membrane exocytosis 2 | -0.0790223 |
| MAP1B | microtubule-associated protein 1B | -0.0773724 |
| KCNB2 | potassium channel, voltage gated Shab related subfamily B, member 2 | -0.0747375 |
| ESRRG | estrogen-related receptor gamma | -0.0734763 |
| PEG10 | paternally expressed 10 | -0.0729031 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0723133 |
| ADGRL2 | adhesion G protein-coupled receptor L2 | -0.0678052 |
| PDE10A | phosphodiesterase 10A | -0.0664212 |
| GPC5 | glypican 5 | -0.0638204 |
| CALCA | calcitonin-related polypeptide alpha | -0.0634723 |
| RIT2 | Ras-like without CAAX 2 | -0.063082 |
| GRIK1 | glutamate receptor, ionotropic, kainate 1 | -0.0607755 |
| ROBO1 | roundabout, axon guidance receptor, homolog 1 (Drosophila) | -0.0570537 |
| IGFBP5 | insulin-like growth factor binding protein 5 | -0.0549732 |
| TSHZ2 | teashirt zinc finger homeobox 2 | -0.0540206 |
| CACNA1A | calcium channel, voltage-dependent, P/Q type, alpha 1A subunit | -0.0524203 |
| MYCBP2 | MYC binding protein 2, E3 ubiquitin protein ligase | -0.0520971 |
| SYT1 | synaptotagmin I | -0.0497156 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0493914 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | -0.0484546 |
| SMYD3 | SET and MYND domain containing 3 | -0.0479751 |
| TMSB4X | thymosin beta 4, X-linked | -0.0474696 |
| RORA | RAR-related orphan receptor A | -0.0471739 |
| CNKSR3 | CNKSR family member 3 | -0.0466817 |
| SGIP1 | SH3-domain GRB2-like (endophilin) interacting protein 1 | -0.0439662 |
| FOXC1 | forkhead box C1 | -0.043355 |
| PCSK1 | proprotein convertase subtilisin/kexin type 1 | -0.038778 |
| GNAS | GNAS complex locus | -0.038187 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0379222 |
| DGKB | diacylglycerol kinase, beta 90kDa | -0.0374208 |
| ACTG1 | actin gamma 1 | -0.0370903 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.0367339 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | -0.0366779 |
| ST18 | suppression of tumorigenicity 18, zinc finger | -0.0363864 |
| BACE2 | beta-site APP-cleaving enzyme 2 | -0.0363585 |
| ARB2A | ARB2 cotranscriptional regulator A | -0.0357455 |
| CAMK1D | calcium/calmodulin-dependent protein kinase ID | -0.0357327 |
| TAX1BP1 | Tax1 (human T-cell leukemia virus type I) binding protein 1 | -0.0355248 |
| KIF26B | kinesin family member 26B | -0.0352357 |
| DTNA | dystrobrevin, alpha | -0.0341619 |
| TPM4 | tropomyosin 4 | -0.0337629 |
| RIGI | RNA sensor RIG-I | -0.0332787 |
| EPHA6 | EPH receptor A6 | -0.0327594 |
| SINHCAF | SIN3-HDAC complex associated factor | -0.0327282 |
| TPD52 | tumor protein D52 | -0.0326607 |
| GNL3L | guanine nucleotide binding protein-like 3 (nucleolar)-like | -0.0321489 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0320891 |
| FAAH2 | fatty acid amide hydrolase 2 | -0.0315975 |
| KCTD8 | potassium channel tetramerization domain containing 8 | -0.030564 |
| EIF2AK2 | eukaryotic translation initiation factor 2-alpha kinase 2 | -0.0305073 |
| ASH1L | ash1 (absent, small, or homeotic)-like (Drosophila) | -0.0302953 |
| EGLN3 | egl-9 family hypoxia-inducible factor 3 | -0.0302541 |
| FGF14 | fibroblast growth factor 14 | -0.0302287 |
| YWHAE | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon | -0.0302011 |
| PITPNM2 | phosphatidylinositol transfer protein, membrane-associated 2 | -0.0301796 |
| CHD7 | chromodomain helicase DNA binding protein 7 | -0.0295297 |
| TPR | translocated promoter region, nuclear basket protein | -0.0293037 |
| MARCHF6 | membrane associated ring-CH-type finger 6 | -0.029115 |
| TCF12 | transcription factor 12 | -0.0289999 |
| KTN1 | kinectin 1 (kinesin receptor) | -0.02899 |
| HM13 | histocompatibility (minor) 13 | -0.0288574 |
| IFI6 | interferon, alpha-inducible protein 6 | -0.0284838 |
| PEX5L | peroxisomal biogenesis factor 5-like | -0.0280735 |
| COL22A1 | collagen, type XXII, alpha 1 | -0.0278965 |
| STC1 | stanniocalcin 1 | -0.0275445 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0274018 |
| TNRC6B | trinucleotide repeat containing 6B | -0.027241 |
| ATP5F1B | ATP synthase F1 subunit beta | -0.0270887 |
| ZC3H12B | zinc finger CCCH-type containing 12B | -0.0270532 |
| ZNF395 | zinc finger protein 395 | -0.0264798 |
| RPL6 | ribosomal protein L6 | -0.0264757 |
| SMARCC1 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 1 | -0.0264606 |
| AGBL4 | ATP/GTP binding protein-like 4 | -0.0263576 |
| RAB2A | RAB2A, member RAS oncogene family | -0.0263449 |
| RAD21 | RAD21 homolog (S. pombe) | -0.0261029 |
| UBB | ubiquitin B | -0.0260746 |
| NCOR1 | nuclear receptor corepressor 1 | -0.0260024 |
| H1-0 | H1.0 linker histone | -0.0259713 |
| DDX17 | DEAD (Asp-Glu-Ala-Asp) box helicase 17 | -0.0258811 |
| WDR45B | WD repeat domain 45B | -0.0256335 |
| RPL11 | ribosomal protein L11 | -0.0256161 |
| SLCO3A1 | solute carrier organic anion transporter family, member 3A1 | -0.0255256 |
| NIPSNAP2 | nipsnap homolog 2 | -0.0254563 |
| RERE | arginine-glutamic acid dipeptide (RE) repeats | -0.025375 |
| CACNA1D | calcium channel, voltage-dependent, L type, alpha 1D subunit | -0.0252867 |
| PGK1 | phosphoglycerate kinase 1 | -0.0251976 |
| SF3B2 | splicing factor 3b, subunit 2, 145kDa | -0.0251027 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0250792 |
| ASIC2 | acid sensing (proton gated) ion channel 2 | -0.0250031 |
| KCNMB3 | potassium channel subfamily M regulatory beta subunit 3 | -0.0249966 |
