| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | (R)-Verapamil (hydrochloride) perturbation in SK-MEL-2 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the (R)-Verapamil (hydrochloride)_SK-MEL-2 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| SERPINA3 | serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 3 | 0.0729127 |
| IGFBP3 | insulin-like growth factor binding protein 3 | 0.0704371 |
| ANGPTL4 | angiopoietin-like 4 | 0.0606182 |
| FLNB | filamin B, beta | 0.0538234 |
| PFKFB4 | 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 4 | 0.0532528 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | 0.0495094 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0490056 |
| DST | dystonin | 0.0474901 |
| CFAP20DC | CFAP20 domain containing | 0.0439411 |
| CENPF | centromere protein F, 350/400kDa | 0.0423359 |
| NAV2 | neuron navigator 2 | 0.0410675 |
| RPS4X | ribosomal protein S4, X-linked | 0.0405497 |
| YWHAG | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma | 0.0399813 |
| NDRG1 | N-myc downstream regulated 1 | 0.0399793 |
| KMT2E | lysine (K)-specific methyltransferase 2E | 0.0390769 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0381942 |
| SIPA1L1 | signal-induced proliferation-associated 1 like 1 | 0.0369298 |
| NOTCH2 | notch 2 | 0.0363627 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0352209 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | 0.0345001 |
| MSN | moesin | 0.0328335 |
| GALNT2 | polypeptide N-acetylgalactosaminyltransferase 2 | 0.0326251 |
| ATXN1 | ataxin 1 | 0.0321924 |
| NRG3 | neuregulin 3 | 0.0321736 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0320799 |
| KTN1 | kinectin 1 (kinesin receptor) | 0.0311202 |
| ASPH | aspartate beta-hydroxylase | 0.0304146 |
| AMOTL1 | angiomotin like 1 | 0.0303151 |
| MKI67 | marker of proliferation Ki-67 | 0.0302149 |
| MORF4L2 | mortality factor 4 like 2 | 0.0297805 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0288167 |
| STAT3 | signal transducer and activator of transcription 3 (acute-phase response factor) | 0.0285815 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | 0.0274594 |
| PRRC2C | proline-rich coiled-coil 2C | 0.0268314 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | 0.0261184 |
| PHF21A | PHD finger protein 21A | 0.0259876 |
| FUS | FUS RNA binding protein | 0.0258909 |
| DIP2C | DIP2 disco-interacting protein 2 homolog C (Drosophila) | 0.0256132 |
| PPFIBP1 | PTPRF interacting protein, binding protein 1 (liprin beta 1) | 0.0255585 |
| NFE2L1 | nuclear factor, erythroid 2-like 1 | 0.0255365 |
| LAMB1 | laminin, beta 1 | 0.0249414 |
| SEPTIN9 | septin 9 | 0.0248701 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | 0.0239525 |
| VEGFA | vascular endothelial growth factor A | 0.0233809 |
| PTK2 | protein tyrosine kinase 2 | 0.0231757 |
| NLGN1 | neuroligin 1 | 0.0228407 |
| CTNNB1 | catenin (cadherin-associated protein), beta 1, 88kDa | 0.0227761 |
| SHC4 | SHC (Src homology 2 domain containing) family, member 4 | 0.0224136 |
| PKM | pyruvate kinase, muscle | 0.0223766 |
| B2M | beta-2-microglobulin | 0.0223372 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0222989 |
| SPAG9 | sperm associated antigen 9 | 0.0222526 |
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa | 0.0219508 |
| ACTN1 | actinin, alpha 1 | 0.0219327 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | 0.021798 |
| TNS1 | tensin 1 | 0.0215549 |
| IGF2BP3 | insulin-like growth factor 2 mRNA binding protein 3 | 0.0212025 |
| RPL23 | ribosomal protein L23 | 0.0210274 |
| ABTB2 | ankyrin repeat and BTB (POZ) domain containing 2 | 0.0210044 |
| SOX10 | SRY (sex determining region Y)-box 10 | 0.0209898 |
| EIF2AK2 | eukaryotic translation initiation factor 2-alpha kinase 2 | 0.0209047 |
| LEF1 | lymphoid enhancer-binding factor 1 | 0.0207007 |
| RPS12 | ribosomal protein S12 | 0.0205942 |
| ARID1B | AT rich interactive domain 1B (SWI1-like) | 0.0203106 |
| ZMIZ1 | zinc finger, MIZ-type containing 1 | 0.0202523 |
| MBNL1 | muscleblind-like splicing regulator 1 | 0.0197588 |
| CTBP2 | C-terminal binding protein 2 | 0.0197032 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | 0.0196071 |
| ZMIZ2 | zinc finger, MIZ-type containing 2 | 0.0193543 |
| DPY19L1 | dpy-19-like 1 (C. elegans) | 0.0192124 |
| FMNL2 | formin-like 2 | 0.0191957 |
| HDAC4 | histone deacetylase 4 | 0.0190391 |
| CYB5R3 | cytochrome b5 reductase 3 | 0.0189253 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | 0.0183826 |
| SMAD3 | SMAD family member 3 | 0.0183567 |
| CABIN1 | calcineurin binding protein 1 | 0.0182441 |
| NAV1 | neuron navigator 1 | 0.0180625 |
| SPATS2L | spermatogenesis associated, serine-rich 2-like | 0.0179717 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.0179665 |
| APOLD1 | apolipoprotein L domain containing 1 | 0.0179422 |
| BHLHE40 | basic helix-loop-helix family, member e40 | 0.0177656 |
| PRELID2 | PRELI domain containing 2 | 0.0177121 |
| SLC2A3 | solute carrier family 2 (facilitated glucose transporter), member 3 | 0.017577 |
| ZNRF1 | zinc and ring finger 1, E3 ubiquitin protein ligase | 0.0173659 |
| MARCKS | myristoylated alanine-rich protein kinase C substrate | 0.0172688 |
| RANGAP1 | Ran GTPase activating protein 1 | 0.0172629 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0169401 |
| TENM1 | teneurin transmembrane protein 1 | 0.0166955 |
| RCOR1 | REST corepressor 1 | 0.0164964 |
| CRYBG3 | beta-gamma crystallin domain containing 3 | 0.016244 |
| CTSL | cathepsin L | 0.016172 |
| MLPH | melanophilin | 0.0160912 |
| SYNE2 | spectrin repeat containing, nuclear envelope 2 | 0.0159545 |
| TAC4 | tachykinin 4 (hemokinin) | 0.01593 |
| AFDN | afadin, adherens junction formation factor | 0.0158574 |
| ARRDC3 | arrestin domain containing 3 | 0.0158476 |
| GRID2 | glutamate receptor, ionotropic, delta 2 | 0.0157697 |
| HNRNPA3 | heterogeneous nuclear ribonucleoprotein A3 | 0.0156773 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.0156118 |
| EZR | ezrin | 0.0156088 |
| Symbol | Name | Standardized Value |
|---|---|---|
| FMN1 | formin 1 | -0.281347 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.243989 |
| FN1 | fibronectin 1 | -0.221712 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.144682 |
| FRMD4A | FERM domain containing 4A | -0.133472 |
| VIM | vimentin | -0.12316 |
| LSAMP | limbic system-associated membrane protein | -0.110405 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.106156 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0771731 |
| GOLGA4 | golgin A4 | -0.0713015 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0679028 |
| SQSTM1 | sequestosome 1 | -0.0650042 |
| PGK1 | phosphoglycerate kinase 1 | -0.0649949 |
| PMEL | premelanosome protein | -0.0641788 |
| SERPINE2 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 | -0.0625347 |
| VDAC1 | voltage-dependent anion channel 1 | -0.0549598 |
| FHIT | fragile histidine triad | -0.0534225 |
| RAB7A | RAB7A, member RAS oncogene family | -0.0503027 |
| IL1RAPL1 | interleukin 1 receptor accessory protein-like 1 | -0.0495976 |
| ACTG1 | actin gamma 1 | -0.0494251 |
| KAZN | kazrin, periplakin interacting protein | -0.0455981 |
| CCND1 | cyclin D1 | -0.0436178 |
| FRMD5 | FERM domain containing 5 | -0.0405683 |
| CANX | calnexin | -0.0378018 |
| ANKRD1 | ankyrin repeat domain 1 (cardiac muscle) | -0.0373401 |
| BCAS3 | breast carcinoma amplified sequence 3 | -0.0367605 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0367591 |
| SREBF2 | sterol regulatory element binding transcription factor 2 | -0.0367573 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0337465 |
| TXNRD1 | thioredoxin reductase 1 | -0.0324471 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | -0.0320336 |
| RHOBTB3 | Rho-related BTB domain containing 3 | -0.0312541 |
| ERBIN | erbb2 interacting protein | -0.0310111 |
| ST13 | suppression of tumorigenicity 13 (colon carcinoma) (Hsp70 interacting protein) | -0.0309021 |
| RASAL2 | RAS protein activator like 2 | -0.0298898 |
| CALU | calumenin | -0.0292037 |
| SMYD3 | SET and MYND domain containing 3 | -0.0287713 |
| FILIP1 | filamin A interacting protein 1 | -0.0281409 |
| MARCHF1 | membrane associated ring-CH-type finger 1 | -0.0280863 |
| KPNB1 | karyopherin (importin) beta 1 | -0.0278868 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | -0.0277371 |
| FNIP1 | folliculin interacting protein 1 | -0.0274731 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | -0.0271384 |
| ICAM1 | intercellular adhesion molecule 1 | -0.0269152 |
| CA8 | carbonic anhydrase VIII | -0.0267485 |
| TPTEP2-CSNK1E | TPTEP2-CSNK1E readthrough | -0.0267246 |
| SLC25A36 | solute carrier family 25 (pyrimidine nucleotide carrier), member 36 | -0.0267043 |
| RALY | RALY heterogeneous nuclear ribonucleoprotein | -0.0258276 |
| TAS2R14 | taste receptor, type 2, member 14 | -0.0256614 |
| CADM1 | cell adhesion molecule 1 | -0.0256331 |
| TP63 | tumor protein p63 | -0.0255932 |
| COA1 | cytochrome c oxidase assembly factor 1 homolog (S. cerevisiae) | -0.0251793 |
| FSTL5 | follistatin-like 5 | -0.0249197 |
| COMMD10 | COMM domain containing 10 | -0.024887 |
| TNNC1 | troponin C type 1 (slow) | -0.0248296 |
| TASOR2 | transcription activation suppressor family member 2 | -0.0247295 |
| DNAH14 | dynein, axonemal, heavy chain 14 | -0.0246468 |
| EEF2 | eukaryotic translation elongation factor 2 | -0.0239281 |
| PPFIA1 | protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 1 | -0.0238651 |
| NRXN3 | neurexin 3 | -0.0236483 |
| MON2 | MON2 homolog (S. cerevisiae) | -0.0234454 |
| FBXW11 | F-box and WD repeat domain containing 11 | -0.0233443 |
| TFRC | transferrin receptor | -0.0233425 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | -0.0232909 |
| HDAC8 | histone deacetylase 8 | -0.0232389 |
| NKTR | natural killer cell triggering receptor | -0.0230706 |
| FBXL2 | F-box and leucine-rich repeat protein 2 | -0.0230656 |
| RHOA | ras homolog family member A | -0.0228342 |
| PCNX4 | pecanex 4 | -0.0228282 |
| HDLBP | high density lipoprotein binding protein | -0.0227369 |
| SENP5 | SUMO1/sentrin specific peptidase 5 | -0.0226783 |
| RTN4 | reticulon 4 | -0.0224851 |
| NF1 | neurofibromin 1 | -0.022427 |
| ZCCHC7 | zinc finger, CCHC domain containing 7 | -0.0222651 |
| GLS2 | glutaminase 2 (liver, mitochondrial) | -0.0220283 |
| RPLP0 | ribosomal protein, large, P0 | -0.0216081 |
| CSDE1 | cold shock domain containing E1, RNA-binding | -0.0213275 |
| GPATCH8 | G patch domain containing 8 | -0.0212488 |
| RBM25 | RNA binding motif protein 25 | -0.0212291 |
| TMEM263 | transmembrane protein 263 | -0.0211888 |
| PLSCR1 | phospholipid scramblase 1 | -0.0211784 |
| YWHAB | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta | -0.0208546 |
| PRRC2B | proline-rich coiled-coil 2B | -0.0207984 |
| CLINT1 | clathrin interactor 1 | -0.0204901 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.0204819 |
| RPL4 | ribosomal protein L4 | -0.0203083 |
| ULK4 | unc-51 like kinase 4 | -0.0202946 |
| ZNF644 | zinc finger protein 644 | -0.0199822 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0198827 |
| FTL | ferritin, light polypeptide | -0.019867 |
| RBMS3 | RNA binding motif, single stranded interacting protein 3 | -0.0196434 |
| ST3GAL6 | ST3 beta-galactoside alpha-2,3-sialyltransferase 6 | -0.0195861 |
| SOD2 | superoxide dismutase 2, mitochondrial | -0.0194619 |
| RBM39 | RNA binding motif protein 39 | -0.0192516 |
| DDX17 | DEAD (Asp-Glu-Ala-Asp) box helicase 17 | -0.0189326 |
| DDX5 | DEAD (Asp-Glu-Ala-Asp) box helicase 5 | -0.0188988 |
| RERG | RAS-like, estrogen-regulated, growth inhibitor | -0.0187665 |
| NEDD4L | neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase | -0.0186884 |
| TBCA | tubulin folding cofactor A | -0.0185113 |
| SOX6 | SRY (sex determining region Y)-box 6 | -0.0184437 |
