| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | (R)-Verapamil (hydrochloride) perturbation in SNU-1 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the (R)-Verapamil (hydrochloride)_SNU-1 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | 0.0991927 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0921845 |
| ADAM10 | ADAM metallopeptidase domain 10 | 0.0745657 |
| TXNRD1 | thioredoxin reductase 1 | 0.065935 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | 0.062482 |
| GOLGA4 | golgin A4 | 0.0548734 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | 0.0518522 |
| NQO1 | NAD(P)H dehydrogenase, quinone 1 | 0.045979 |
| SMC3 | structural maintenance of chromosomes 3 | 0.0455809 |
| TMF1 | TATA element modulatory factor 1 | 0.0444533 |
| SHC1 | SHC (Src homology 2 domain containing) transforming protein 1 | 0.0426108 |
| CENPF | centromere protein F, 350/400kDa | 0.0414545 |
| LUC7L3 | LUC7-like 3 (S. cerevisiae) | 0.0413872 |
| PHIP | pleckstrin homology domain interacting protein | 0.0389188 |
| FLNB | filamin B, beta | 0.0382959 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | 0.0372974 |
| SET | SET nuclear proto-oncogene | 0.036658 |
| WSB1 | WD repeat and SOCS box containing 1 | 0.0357908 |
| PRRC2C | proline-rich coiled-coil 2C | 0.0357592 |
| ZBTB20 | zinc finger and BTB domain containing 20 | 0.0349649 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.0341227 |
| BRWD1 | bromodomain and WD repeat domain containing 1 | 0.0338766 |
| KHDRBS1 | KH domain containing, RNA binding, signal transduction associated 1 | 0.0338665 |
| NAV2 | neuron navigator 2 | 0.0324115 |
| CCDC88A | coiled-coil domain containing 88A | 0.0323688 |
| RAB6A | RAB6A, member RAS oncogene family | 0.0317205 |
| TRERF1 | transcriptional regulating factor 1 | 0.0314638 |
| DOCK3 | dedicator of cytokinesis 3 | 0.0313801 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | 0.030599 |
| TXNIP | thioredoxin interacting protein | 0.0302169 |
| MXI1 | MAX interactor 1, dimerization protein | 0.0298812 |
| PHF21A | PHD finger protein 21A | 0.0297198 |
| RNF145 | ring finger protein 145 | 0.0296637 |
| ZMYM2 | zinc finger, MYM-type 2 | 0.0293822 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.0292591 |
| KIF5B | kinesin family member 5B | 0.0291618 |
| HELZ | helicase with zinc finger | 0.0282985 |
| ARID2 | AT rich interactive domain 2 (ARID, RFX-like) | 0.0281302 |
| NOP58 | NOP58 ribonucleoprotein | 0.0276673 |
| CCNL1 | cyclin L1 | 0.0273434 |
| SPAG9 | sperm associated antigen 9 | 0.0265625 |
| IBTK | inhibitor of Bruton agammaglobulinemia tyrosine kinase | 0.0263206 |
| THOC2 | THO complex 2 | 0.0256941 |
| KDM3A | lysine (K)-specific demethylase 3A | 0.0254479 |
| MORF4L2 | mortality factor 4 like 2 | 0.0253836 |
| RBM25 | RNA binding motif protein 25 | 0.0253253 |
| MT2A | metallothionein 2A | 0.0250402 |
| GCLM | glutamate-cysteine ligase, modifier subunit | 0.0250086 |
| HDAC9 | histone deacetylase 9 | 0.0249678 |
| SETD5 | SET domain containing 5 | 0.0247497 |
| PJA2 | praja ring finger 2, E3 ubiquitin protein ligase | 0.0246952 |
| SBF2 | SET binding factor 2 | 0.0245977 |
| ZNF292 | zinc finger protein 292 | 0.0242272 |
| TPR | translocated promoter region, nuclear basket protein | 0.0239333 |
| DDX3Y | DEAD (Asp-Glu-Ala-Asp) box helicase 3, Y-linked | 0.023578 |
| SEPTIN7 | septin 7 | 0.0234338 |
| FAM13A | family with sequence similarity 13, member A | 0.0232276 |
| CITED2 | Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2 | 0.023169 |
| TOB1 | transducer of ERBB2, 1 | 0.0230662 |
| SMC4 | structural maintenance of chromosomes 4 | 0.0229918 |
| LDHA | lactate dehydrogenase A | 0.0229723 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | 0.0228573 |
| ZRANB2 | zinc finger, RAN-binding domain containing 2 | 0.0226997 |
| DSTN | destrin (actin depolymerizing factor) | 0.0225193 |
| MKI67 | marker of proliferation Ki-67 | 0.0225021 |
| ELOVL5 | ELOVL fatty acid elongase 5 | 0.0222065 |
| PTCH1 | patched 1 | 0.0221733 |
| LPCAT1 | lysophosphatidylcholine acyltransferase 1 | 0.0221191 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | 0.0220297 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0219584 |
| CALU | calumenin | 0.0219431 |
| PHC3 | polyhomeotic homolog 3 (Drosophila) | 0.021705 |
| RBBP6 | retinoblastoma binding protein 6 | 0.021649 |
| LRBA | LPS-responsive vesicle trafficking, beach and anchor containing | 0.02162 |
| WDR45B | WD repeat domain 45B | 0.0215676 |
| UPF2 | UPF2 regulator of nonsense transcripts homolog (yeast) | 0.0214749 |
| KTN1 | kinectin 1 (kinesin receptor) | 0.0214212 |
| CHD1 | chromodomain helicase DNA binding protein 1 | 0.02135 |
| SEC23A | Sec23 homolog A (S. cerevisiae) | 0.0210585 |
| CHD7 | chromodomain helicase DNA binding protein 7 | 0.021058 |
| TPX2 | TPX2, microtubule-associated | 0.0210473 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | 0.0207997 |
| ZNF148 | zinc finger protein 148 | 0.0206623 |
| RB1CC1 | RB1-inducible coiled-coil 1 | 0.0206339 |
| COPA | coatomer protein complex, subunit alpha | 0.0206112 |
| AGPAT5 | 1-acylglycerol-3-phosphate O-acyltransferase 5 | 0.0205024 |
| SF3B1 | splicing factor 3b, subunit 1, 155kDa | 0.0204568 |
| CSNK1A1 | casein kinase 1, alpha 1 | 0.0202232 |
| ANP32B | acidic (leucine-rich) nuclear phosphoprotein 32 family, member B | 0.0199555 |
| EXOC6B | exocyst complex component 6B | 0.0199423 |
| B2M | beta-2-microglobulin | 0.0199157 |
| SNAPC3 | small nuclear RNA activating complex, polypeptide 3, 50kDa | 0.0199149 |
| TPM4 | tropomyosin 4 | 0.019842 |
| PCM1 | pericentriolar material 1 | 0.0196759 |
| PDS5A | PDS5 cohesin associated factor A | 0.0196664 |
| PRKRIP1 | PRKR interacting protein 1 (IL11 inducible) | 0.0196631 |
| DARS1 | aspartyl-tRNA synthetase 1 | 0.0195941 |
| CUL5 | cullin 5 | 0.0195822 |
| ENO1 | enolase 1, (alpha) | 0.0193172 |
| CKAP2 | cytoskeleton associated protein 2 | 0.0193086 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.252718 |
| B3GALT1 | UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 1 | -0.211282 |
| CPED1 | cadherin-like and PC-esterase domain containing 1 | -0.185834 |
| PDE4B | phosphodiesterase 4B, cAMP-specific | -0.176005 |
| AHNAK | AHNAK nucleoprotein | -0.164663 |
| VCL | vinculin | -0.144362 |
| BMP10 | bone morphogenetic protein 10 | -0.121971 |
| RBMS3 | RNA binding motif, single stranded interacting protein 3 | -0.113865 |
| INPP4B | inositol polyphosphate-4-phosphatase, type II, 105kDa | -0.106176 |
| PTMA | prothymosin, alpha | -0.10551 |
| DLG1 | discs, large homolog 1 (Drosophila) | -0.102481 |
| RPL35A | ribosomal protein L35a | -0.0863075 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.08619 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0780775 |
| RPS6 | ribosomal protein S6 | -0.0752448 |
| ACTG1 | actin gamma 1 | -0.0722759 |
| RPLP1 | ribosomal protein, large, P1 | -0.0720599 |
| RPL34 | ribosomal protein L34 | -0.0707097 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.0678185 |
| PDGFC | platelet derived growth factor C | -0.0659622 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0645885 |
| SSBP2 | single-stranded DNA binding protein 2 | -0.0612809 |
| CACNB4 | calcium channel, voltage-dependent, beta 4 subunit | -0.058794 |
| ALDH1A2 | aldehyde dehydrogenase 1 family, member A2 | -0.0580988 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0572492 |
| INTS6 | integrator complex subunit 6 | -0.0570145 |
| RPS19 | ribosomal protein S19 | -0.0565013 |
| TNFRSF11B | tumor necrosis factor receptor superfamily, member 11b | -0.0555438 |
| GLI3 | GLI family zinc finger 3 | -0.0548166 |
| RPS8 | ribosomal protein S8 | -0.0501754 |
| GLI2 | GLI family zinc finger 2 | -0.050166 |
| CCND1 | cyclin D1 | -0.049948 |
| DIAPH3 | diaphanous-related formin 3 | -0.048358 |
| TMSB4X | thymosin beta 4, X-linked | -0.0479192 |
| ENOX1 | ecto-NOX disulfide-thiol exchanger 1 | -0.0477261 |
| RHOA | ras homolog family member A | -0.0464806 |
| TTC28 | tetratricopeptide repeat domain 28 | -0.0464395 |
| NBEA | neurobeachin | -0.0463325 |
| RPS27A | ribosomal protein S27a | -0.0461637 |
| AEBP2 | AE binding protein 2 | -0.0459055 |
| EGFR | epidermal growth factor receptor | -0.0455167 |
| RPS25 | ribosomal protein S25 | -0.045266 |
| RPL31 | ribosomal protein L31 | -0.0446724 |
| RPL4 | ribosomal protein L4 | -0.0445448 |
| TAS2R14 | taste receptor, type 2, member 14 | -0.044116 |
| SLC38A2 | solute carrier family 38, member 2 | -0.0440711 |
| NCEH1 | neutral cholesterol ester hydrolase 1 | -0.0434716 |
| RPL19 | ribosomal protein L19 | -0.0433023 |
| EEF1G | eukaryotic translation elongation factor 1 gamma | -0.0426771 |
| SLC5A3 | solute carrier family 5 (sodium/myo-inositol cotransporter), member 3 | -0.0418883 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.0418571 |
| MYO5C | myosin VC | -0.0414887 |
| BMP2K | BMP2 inducible kinase | -0.0412587 |
| RPL12 | ribosomal protein L12 | -0.0407928 |
| CRPPA | CDP-L-ribitol pyrophosphorylase A | -0.0407236 |
| FOXP1 | forkhead box P1 | -0.0403372 |
| MTHFD1L | methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1-like | -0.0399831 |
| UNC13A | unc-13 homolog A (C. elegans) | -0.0395354 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | -0.0382962 |
| POTEF | POTE ankyrin domain family, member F | -0.037833 |
| RPS13 | ribosomal protein S13 | -0.036923 |
| FER1L6 | fer-1-like family member 6 | -0.0366494 |
| LRPPRC | leucine-rich pentatricopeptide repeat containing | -0.0363254 |
| PDE7B | phosphodiesterase 7B | -0.0363048 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.0361927 |
| SLC1A3 | solute carrier family 1 (glial high affinity glutamate transporter), member 3 | -0.036042 |
| RPL11 | ribosomal protein L11 | -0.0357317 |
| RPL23 | ribosomal protein L23 | -0.0357196 |
| EXT1 | exostosin glycosyltransferase 1 | -0.0356635 |
| RPL7A | ribosomal protein L7a | -0.0356238 |
| RPS21 | ribosomal protein S21 | -0.0355959 |
| RPS23 | ribosomal protein S23 | -0.0355797 |
| EEF2 | eukaryotic translation elongation factor 2 | -0.0355398 |
| ASCC3 | activating signal cointegrator 1 complex subunit 3 | -0.0355309 |
| EIF4G3 | eukaryotic translation initiation factor 4 gamma, 3 | -0.0354781 |
| GALNT5 | polypeptide N-acetylgalactosaminyltransferase 5 | -0.0354657 |
| RPLP2 | ribosomal protein, large, P2 | -0.0354135 |
| ASAP1 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 | -0.0348631 |
| EVI5 | ecotropic viral integration site 5 | -0.0346096 |
| RPL26 | ribosomal protein L26 | -0.0341276 |
| RPS24 | ribosomal protein S24 | -0.033454 |
| RPL9 | ribosomal protein L9 | -0.032714 |
| RPL28 | ribosomal protein L28 | -0.0323404 |
| RPL32 | ribosomal protein L32 | -0.0322778 |
| RPL37A | ribosomal protein L37a | -0.0321346 |
| S100A9 | S100 calcium binding protein A9 | -0.0320452 |
| DPYD | dihydropyrimidine dehydrogenase | -0.0318491 |
| NFE2L2 | nuclear factor, erythroid 2-like 2 | -0.0318212 |
| RPS16 | ribosomal protein S16 | -0.031651 |
| RPLP0 | ribosomal protein, large, P0 | -0.0316237 |
| ZEB1 | zinc finger E-box binding homeobox 1 | -0.0315739 |
| HSPH1 | heat shock 105kDa/110kDa protein 1 | -0.0313169 |
| PRG2 | proteoglycan 2, bone marrow (natural killer cell activator, eosinophil granule major basic protein) | -0.0308585 |
| EFNA5 | ephrin-A5 | -0.0308186 |
| TEAD1 | TEA domain family member 1 (SV40 transcriptional enhancer factor) | -0.0301986 |
| ZNF217 | zinc finger protein 217 | -0.0301651 |
| GNB1 | guanine nucleotide binding protein (G protein), beta polypeptide 1 | -0.0299425 |
| CAMKMT | calmodulin-lysine N-methyltransferase | -0.0296853 |
| HEG1 | heart development protein with EGF-like domains 1 | -0.0293212 |
| S100A6 | S100 calcium binding protein A6 | -0.0289234 |
