| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | (R)-Verapamil (hydrochloride) perturbation in SNU-423 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the (R)-Verapamil (hydrochloride)_SNU-423 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| IGFBP3 | insulin-like growth factor binding protein 3 | 0.127536 |
| GLIS3 | GLIS family zinc finger 3 | 0.117667 |
| IQCJ-SCHIP1 | IQCJ-SCHIP1 readthrough | 0.115138 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.108329 |
| HDAC9 | histone deacetylase 9 | 0.107334 |
| NDRG1 | N-myc downstream regulated 1 | 0.0974921 |
| HMGA2 | high mobility group AT-hook 2 | 0.0902533 |
| COL6A3 | collagen, type VI, alpha 3 | 0.0818717 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | 0.0781907 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | 0.0647457 |
| MT2A | metallothionein 2A | 0.0639208 |
| SEPTIN9 | septin 9 | 0.0636838 |
| VCAN | versican | 0.0633982 |
| LDHA | lactate dehydrogenase A | 0.0611996 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | 0.0598716 |
| ABCA1 | ATP-binding cassette, sub-family A (ABC1), member 1 | 0.0597885 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0597849 |
| MAGI2 | membrane associated guanylate kinase, WW and PDZ domain containing 2 | 0.0595302 |
| ZBTB38 | zinc finger and BTB domain containing 38 | 0.0587106 |
| HLA-B | major histocompatibility complex, class I, B | 0.0565944 |
| RPS4X | ribosomal protein S4, X-linked | 0.0557357 |
| GPC6 | glypican 6 | 0.0547344 |
| INTS6 | integrator complex subunit 6 | 0.0546414 |
| RPS12 | ribosomal protein S12 | 0.0539652 |
| FRMD4A | FERM domain containing 4A | 0.0507307 |
| TPT1 | tumor protein, translationally-controlled 1 | 0.0476923 |
| ASPH | aspartate beta-hydroxylase | 0.0475052 |
| STC1 | stanniocalcin 1 | 0.0459897 |
| SQSTM1 | sequestosome 1 | 0.045835 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0451827 |
| CDH13 | cadherin 13 | 0.0443348 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.0431217 |
| TMEM132D | transmembrane protein 132D | 0.0427329 |
| SFTPA2 | surfactant protein A2 | 0.0426211 |
| NAV1 | neuron navigator 1 | 0.0420934 |
| ZMIZ1 | zinc finger, MIZ-type containing 1 | 0.0406276 |
| ITGA3 | integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor) | 0.0405993 |
| COL5A1 | collagen, type V, alpha 1 | 0.0400387 |
| EGFR | epidermal growth factor receptor | 0.0400386 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | 0.0399764 |
| NHS | Nance-Horan syndrome (congenital cataracts and dental anomalies) | 0.0389832 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | 0.0387819 |
| RPL37A | ribosomal protein L37a | 0.0384083 |
| EFNA5 | ephrin-A5 | 0.0371218 |
| IER3 | immediate early response 3 | 0.0368865 |
| LAMC1 | laminin, gamma 1 (formerly LAMB2) | 0.0352714 |
| GRIN2A | glutamate receptor, ionotropic, N-methyl D-aspartate 2A | 0.0346786 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.0331754 |
| INHBA | inhibin, beta A | 0.0328626 |
| BICC1 | BicC family RNA binding protein 1 | 0.0326195 |
| SIPA1L1 | signal-induced proliferation-associated 1 like 1 | 0.0325186 |
| FBXL7 | F-box and leucine-rich repeat protein 7 | 0.0319859 |
| BPTF | bromodomain PHD finger transcription factor | 0.0317656 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0306936 |
| MORF4L2 | mortality factor 4 like 2 | 0.030693 |
| RAD51B | RAD51 paralog B | 0.0303045 |
| TGFBI | transforming growth factor, beta-induced, 68kDa | 0.0289407 |
| ARHGAP22 | Rho GTPase activating protein 22 | 0.0286974 |
| DUSP10 | dual specificity phosphatase 10 | 0.0284791 |
| EPAS1 | endothelial PAS domain protein 1 | 0.0283635 |
| HLA-A | major histocompatibility complex, class I, A | 0.0282165 |
| SOX9 | SRY (sex determining region Y)-box 9 | 0.0282028 |
| TBC1D8 | TBC1 domain family, member 8 (with GRAM domain) | 0.0276455 |
| PMEPA1 | prostate transmembrane protein, androgen induced 1 | 0.027591 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0273346 |
| RPS3 | ribosomal protein S3 | 0.027008 |
| RNF213 | ring finger protein 213 | 0.0268067 |
| EXT1 | exostosin glycosyltransferase 1 | 0.0266487 |
| WWOX | WW domain containing oxidoreductase | 0.0264428 |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) | 0.0263656 |
| TBC1D22A | TBC1 domain family, member 22A | 0.0260067 |
| AFF3 | AF4/FMR2 family, member 3 | 0.0259914 |
| FLNB | filamin B, beta | 0.025629 |
| NEDD4L | neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase | 0.0254112 |
| PPFIBP1 | PTPRF interacting protein, binding protein 1 (liprin beta 1) | 0.0253334 |
| SVIL | supervillin | 0.0251055 |
| CPEB4 | cytoplasmic polyadenylation element binding protein 4 | 0.0247998 |
| EGR1 | early growth response 1 | 0.0247682 |
| FMNL2 | formin-like 2 | 0.0243736 |
| FTL | ferritin, light polypeptide | 0.0243215 |
| CD44 | CD44 molecule (Indian blood group) | 0.0242701 |
| ATXN1 | ataxin 1 | 0.0241879 |
| TNS3 | tensin 3 | 0.0239215 |
| RBMS3 | RNA binding motif, single stranded interacting protein 3 | 0.0236133 |
| TGM2 | transglutaminase 2 | 0.0234832 |
| PRELID2 | PRELI domain containing 2 | 0.0231646 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | 0.0228609 |
| UBASH3B | ubiquitin associated and SH3 domain containing B | 0.0227343 |
| MLPH | melanophilin | 0.0220021 |
| PALM2AKAP2 | PALM2 and AKAP2 fusion | 0.0219335 |
| IFITM3 | interferon induced transmembrane protein 3 | 0.0216829 |
| GFPT2 | glutamine-fructose-6-phosphate transaminase 2 | 0.021615 |
| DOCK5 | dedicator of cytokinesis 5 | 0.0215392 |
| ENO2 | enolase 2 (gamma, neuronal) | 0.0214396 |
| ZHX2 | zinc fingers and homeoboxes 2 | 0.0213816 |
| ANGPTL4 | angiopoietin-like 4 | 0.0212839 |
| PTPN14 | protein tyrosine phosphatase, non-receptor type 14 | 0.0212262 |
| ARID1B | AT rich interactive domain 1B (SWI1-like) | 0.0209268 |
| RUNX1 | runt-related transcription factor 1 | 0.0208527 |
| PTH2R | parathyroid hormone 2 receptor | 0.0208437 |
| Symbol | Name | Standardized Value |
|---|---|---|
| SOD2 | superoxide dismutase 2, mitochondrial | -0.253643 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.178971 |
| FN1 | fibronectin 1 | -0.156129 |
| UGCG | UDP-glucose ceramide glucosyltransferase | -0.095 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.0934477 |
| MYH9 | myosin, heavy chain 9, non-muscle | -0.0689596 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0678914 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | -0.0658157 |
| PGK1 | phosphoglycerate kinase 1 | -0.0595687 |
| RTN4 | reticulon 4 | -0.059383 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0547057 |
| OGA | O-GlcNAcase | -0.054142 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | -0.0534025 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | -0.0530863 |
| ANXA2 | annexin A2 | -0.0516363 |
| CADM1 | cell adhesion molecule 1 | -0.0477073 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0474815 |
| ELL2 | elongation factor, RNA polymerase II, 2 | -0.0470876 |
| FNDC3B | fibronectin type III domain containing 3B | -0.0447825 |
| UBC | ubiquitin C | -0.0445519 |
| VIM | vimentin | -0.0443288 |
| PHLDB2 | pleckstrin homology-like domain, family B, member 2 | -0.044047 |
| ZNF292 | zinc finger protein 292 | -0.0436781 |
| GOLGA4 | golgin A4 | -0.0433285 |
| TPM4 | tropomyosin 4 | -0.0432233 |
| ANLN | anillin, actin binding protein | -0.0421261 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | -0.0416984 |
| RBM39 | RNA binding motif protein 39 | -0.0413229 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | -0.0411426 |
| CENPF | centromere protein F, 350/400kDa | -0.0409442 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0406653 |
| WTAP | Wilms tumor 1 associated protein | -0.04026 |
| SBF2 | SET binding factor 2 | -0.0386416 |
| THBS1 | thrombospondin 1 | -0.0386318 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | -0.0365772 |
| NT5C2 | 5'-nucleotidase, cytosolic II | -0.0362015 |
| LCORL | ligand dependent nuclear receptor corepressor-like | -0.035669 |
| CANX | calnexin | -0.0354867 |
| MKI67 | marker of proliferation Ki-67 | -0.0353993 |
| POLR2A | polymerase (RNA) II (DNA directed) polypeptide A, 220kDa | -0.034839 |
| AHNAK | AHNAK nucleoprotein | -0.0338556 |
| NFKBIZ | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, zeta | -0.0338497 |
| EEF1G | eukaryotic translation elongation factor 1 gamma | -0.0337016 |
| TMSB4X | thymosin beta 4, X-linked | -0.0335204 |
| PTMA | prothymosin, alpha | -0.0335046 |
| TAPBP | TAP binding protein (tapasin) | -0.0330036 |
| TXNRD1 | thioredoxin reductase 1 | -0.0323004 |
| PJA2 | praja ring finger 2, E3 ubiquitin protein ligase | -0.0320721 |
| GNAS | GNAS complex locus | -0.0319822 |
| RB1CC1 | RB1-inducible coiled-coil 1 | -0.0316057 |
| KDM3A | lysine (K)-specific demethylase 3A | -0.0312807 |
| ACSL4 | acyl-CoA synthetase long-chain family member 4 | -0.0311278 |
| MATR3 | matrin 3 | -0.0310783 |
| TNIP1 | TNFAIP3 interacting protein 1 | -0.0310681 |
| CKAP5 | cytoskeleton associated protein 5 | -0.03103 |
| POTEF | POTE ankyrin domain family, member F | -0.0309342 |
| DEK | DEK proto-oncogene | -0.0308278 |
| P4HA2 | prolyl 4-hydroxylase, alpha polypeptide II | -0.0306699 |
| KIF4A | kinesin family member 4A | -0.0303444 |
| TMEM123 | transmembrane protein 123 | -0.0303444 |
| ZFAND3 | zinc finger, AN1-type domain 3 | -0.0302246 |
| DIAPH3 | diaphanous-related formin 3 | -0.0296247 |
| PIK3C2A | phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 alpha | -0.0296223 |
| ACTG1 | actin gamma 1 | -0.0295275 |
| CDCP1 | CUB domain containing protein 1 | -0.0291934 |
| SPAG9 | sperm associated antigen 9 | -0.0289851 |
| DENND5A | DENN/MADD domain containing 5A | -0.0289178 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | -0.0289102 |
| EEF2 | eukaryotic translation elongation factor 2 | -0.0284015 |
| MARCHF6 | membrane associated ring-CH-type finger 6 | -0.0283984 |
| TSC22D2 | TSC22 domain family, member 2 | -0.0282312 |
| SNX9 | sorting nexin 9 | -0.0277904 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | -0.027705 |
| SF3B2 | splicing factor 3b, subunit 2, 145kDa | -0.0270352 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.026927 |
| ATP13A3 | ATPase type 13A3 | -0.0268165 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0266177 |
| ARFGEF2 | ADP-ribosylation factor guanine nucleotide-exchange factor 2 (brefeldin A-inhibited) | -0.0264667 |
| KPNB1 | karyopherin (importin) beta 1 | -0.0264365 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0263991 |
| RHOA | ras homolog family member A | -0.0263332 |
| TMEM41B | transmembrane protein 41B | -0.0263225 |
| SMC4 | structural maintenance of chromosomes 4 | -0.0260041 |
| TPX2 | TPX2, microtubule-associated | -0.0258399 |
| VCL | vinculin | -0.025041 |
| RAD21 | RAD21 homolog (S. pombe) | -0.0247407 |
| ARF4 | ADP-ribosylation factor 4 | -0.0246446 |
| USP9X | ubiquitin specific peptidase 9, X-linked | -0.0245774 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | -0.0244105 |
| PTBP3 | polypyrimidine tract binding protein 3 | -0.0242188 |
| IFIT3 | interferon-induced protein with tetratricopeptide repeats 3 | -0.0241984 |
| NPEPPS | aminopeptidase puromycin sensitive | -0.02401 |
| YBX1 | Y box binding protein 1 | -0.0236801 |
| ICAM1 | intercellular adhesion molecule 1 | -0.023607 |
| MSN | moesin | -0.0235491 |
| BRWD3 | bromodomain and WD repeat domain containing 3 | -0.0235466 |
| TM9SF3 | transmembrane 9 superfamily member 3 | -0.0234727 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | -0.0232041 |
| OPTN | optineurin | -0.0231359 |
| HDLBP | high density lipoprotein binding protein | -0.0226927 |