| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | (R)-Verapamil (hydrochloride) perturbation in SW 1271 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the (R)-Verapamil (hydrochloride)_SW 1271 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| TXNRD1 | thioredoxin reductase 1 | 0.0758158 |
| ANKRD28 | ankyrin repeat domain 28 | 0.0648167 |
| BIRC3 | baculoviral IAP repeat containing 3 | 0.0645856 |
| CD44 | CD44 molecule (Indian blood group) | 0.053965 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.0464273 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | 0.0424926 |
| TAF1D | TATA box binding protein (TBP)-associated factor, RNA polymerase I, D, 41kDa | 0.0414484 |
| CHD1 | chromodomain helicase DNA binding protein 1 | 0.0404216 |
| SMAD3 | SMAD family member 3 | 0.0397546 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | 0.0397466 |
| SMYD3 | SET and MYND domain containing 3 | 0.0390088 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.0371367 |
| PBX3 | pre-B-cell leukemia homeobox 3 | 0.0371238 |
| FMNL2 | formin-like 2 | 0.0365729 |
| YAP1 | Yes-associated protein 1 | 0.0359995 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | 0.0349431 |
| ELL2 | elongation factor, RNA polymerase II, 2 | 0.0333862 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.0330282 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | 0.0315683 |
| CEP295 | centrosomal protein 295kDa | 0.0315399 |
| ANLN | anillin, actin binding protein | 0.0305116 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0303222 |
| DYNC1H1 | dynein, cytoplasmic 1, heavy chain 1 | 0.0300672 |
| PRRC2C | proline-rich coiled-coil 2C | 0.0297703 |
| RPS12 | ribosomal protein S12 | 0.0292908 |
| YBX3 | Y box binding protein 3 | 0.0291931 |
| MATR3 | matrin 3 | 0.028671 |
| MRE11 | MRE11 homolog, double strand break repair nuclease | 0.0283698 |
| ARRDC3 | arrestin domain containing 3 | 0.0279366 |
| ETS1 | v-ets avian erythroblastosis virus E26 oncogene homolog 1 | 0.0272689 |
| DENND4A | DENN/MADD domain containing 4A | 0.0271621 |
| MARCHF4 | membrane associated ring-CH-type finger 4 | 0.0264204 |
| TM9SF2 | transmembrane 9 superfamily member 2 | 0.0258533 |
| MCL1 | myeloid cell leukemia 1 | 0.0255791 |
| PPIG | peptidylprolyl isomerase G (cyclophilin G) | 0.0255473 |
| NCEH1 | neutral cholesterol ester hydrolase 1 | 0.0252916 |
| RNF145 | ring finger protein 145 | 0.0252607 |
| ANKIB1 | ankyrin repeat and IBR domain containing 1 | 0.0251331 |
| ATAD2B | ATPase family, AAA domain containing 2B | 0.0250479 |
| YWHAG | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma | 0.0245238 |
| TSC22D2 | TSC22 domain family, member 2 | 0.0244556 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0241812 |
| ATP2B1 | ATPase, Ca++ transporting, plasma membrane 1 | 0.0240809 |
| ADAM17 | ADAM metallopeptidase domain 17 | 0.0238722 |
| ARL15 | ADP-ribosylation factor-like 15 | 0.0236624 |
| PRPF8 | pre-mRNA processing factor 8 | 0.023644 |
| FLNB | filamin B, beta | 0.0236166 |
| CSNK1A1 | casein kinase 1, alpha 1 | 0.0236105 |
| ANKRD36C | ankyrin repeat domain 36C | 0.0235905 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | 0.0235645 |
| ANO6 | anoctamin 6 | 0.023422 |
| PHC3 | polyhomeotic homolog 3 (Drosophila) | 0.0234141 |
| SCAF8 | SR-related CTD-associated factor 8 | 0.0232437 |
| HUWE1 | HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase | 0.0232297 |
| KTN1 | kinectin 1 (kinesin receptor) | 0.023141 |
| RAB10 | RAB10, member RAS oncogene family | 0.0225303 |
| WNK1 | WNK lysine deficient protein kinase 1 | 0.0224687 |
| ITPR2 | inositol 1,4,5-trisphosphate receptor, type 2 | 0.0223137 |
| TPX2 | TPX2, microtubule-associated | 0.0223135 |
| NCAPD2 | non-SMC condensin I complex, subunit D2 | 0.0221767 |
| IGFBP3 | insulin-like growth factor binding protein 3 | 0.0221551 |
| BAZ2B | bromodomain adjacent to zinc finger domain, 2B | 0.021903 |
| CORO1C | coronin, actin binding protein, 1C | 0.0218839 |
| SVIL | supervillin | 0.0217753 |
| STK24 | serine/threonine kinase 24 | 0.021683 |
| NONO | non-POU domain containing, octamer-binding | 0.0214981 |
| DNAJC5 | DnaJ (Hsp40) homolog, subfamily C, member 5 | 0.0214692 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | 0.0213852 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | 0.0213814 |
| ANKS1A | ankyrin repeat and sterile alpha motif domain containing 1A | 0.021181 |
| ESYT2 | extended synaptotagmin-like protein 2 | 0.0211672 |
| CENPE | centromere protein E, 312kDa | 0.0211368 |
| KIF5B | kinesin family member 5B | 0.0210974 |
| ACTN1 | actinin, alpha 1 | 0.0208571 |
| BCLAF1 | BCL2-associated transcription factor 1 | 0.0208464 |
| PCCA | propionyl CoA carboxylase, alpha polypeptide | 0.0207164 |
| MED13 | mediator complex subunit 13 | 0.0206609 |
| TMF1 | TATA element modulatory factor 1 | 0.0205139 |
| IGF1R | insulin-like growth factor 1 receptor | 0.020331 |
| RPS4X | ribosomal protein S4, X-linked | 0.0202621 |
| CNKSR3 | CNKSR family member 3 | 0.0201007 |
| IL6ST | interleukin 6 signal transducer | 0.0199379 |
| MKI67 | marker of proliferation Ki-67 | 0.0198373 |
| BCL2L1 | BCL2-like 1 | 0.0197837 |
| GIGYF2 | GRB10 interacting GYF protein 2 | 0.0197352 |
| TXNIP | thioredoxin interacting protein | 0.0197281 |
| LRPPRC | leucine-rich pentatricopeptide repeat containing | 0.0197103 |
| RB1CC1 | RB1-inducible coiled-coil 1 | 0.0196134 |
| CENPF | centromere protein F, 350/400kDa | 0.0194967 |
| PTK2 | protein tyrosine kinase 2 | 0.0194858 |
| PANX1 | pannexin 1 | 0.019478 |
| EFNA5 | ephrin-A5 | 0.019364 |
| CAPRIN1 | cell cycle associated protein 1 | 0.0191109 |
| MTREX | Mtr4 exosome RNA helicase | 0.0191007 |
| PHIP | pleckstrin homology domain interacting protein | 0.0189931 |
| PRKN | parkin RBR E3 ubiquitin protein ligase | 0.0189927 |
| KMT2D | lysine (K)-specific methyltransferase 2D | 0.0187725 |
| KIF4A | kinesin family member 4A | 0.0186955 |
| TMX4 | thioredoxin-related transmembrane protein 4 | 0.0186125 |
| IGF2BP3 | insulin-like growth factor 2 mRNA binding protein 3 | 0.0186099 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.385188 |
| TMSB10 | thymosin beta 10 | -0.132875 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.120044 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.106019 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.092632 |
| VIM | vimentin | -0.0913654 |
| INTS6 | integrator complex subunit 6 | -0.0878092 |
| PTMA | prothymosin, alpha | -0.0862956 |
| HMGA2 | high mobility group AT-hook 2 | -0.079484 |
| AHNAK | AHNAK nucleoprotein | -0.0725643 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0722604 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | -0.0704883 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0699663 |
| FNDC3B | fibronectin type III domain containing 3B | -0.0650857 |
| ANXA2 | annexin A2 | -0.0620284 |
| LDHA | lactate dehydrogenase A | -0.0602923 |
| ATG7 | autophagy related 7 | -0.0575498 |
| PCNX4 | pecanex 4 | -0.0515377 |
| FMN1 | formin 1 | -0.0498297 |
| DENND1A | DENN/MADD domain containing 1A | -0.0471945 |
| CANX | calnexin | -0.0465702 |
| RAI14 | retinoic acid induced 14 | -0.0458484 |
| MTHFD1L | methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1-like | -0.0454491 |
| DDX17 | DEAD (Asp-Glu-Ala-Asp) box helicase 17 | -0.0450252 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | -0.0444631 |
| MAP1B | microtubule-associated protein 1B | -0.0424524 |
| RPLP1 | ribosomal protein, large, P1 | -0.0411979 |
| UBE2E2 | ubiquitin-conjugating enzyme E2E 2 | -0.0403347 |
| NUFIP2 | nuclear fragile X mental retardation protein interacting protein 2 | -0.0397211 |
| LPP | LIM domain containing preferred translocation partner in lipoma | -0.0397174 |
| N4BP2L2 | NEDD4 binding protein 2-like 2 | -0.0374787 |
| RPL35A | ribosomal protein L35a | -0.0369357 |
| IARS1 | isoleucyl-tRNA synthetase 1 | -0.0369235 |
| TANC2 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 | -0.0368402 |
| PKM | pyruvate kinase, muscle | -0.0363497 |
| RALY | RALY heterogeneous nuclear ribonucleoprotein | -0.0363379 |
| VCL | vinculin | -0.0362661 |
| HILPDA | hypoxia inducible lipid droplet-associated | -0.0362099 |
| GNAS | GNAS complex locus | -0.036043 |
| TPI1 | triosephosphate isomerase 1 | -0.0356423 |
| LRCH3 | leucine-rich repeats and calponin homology (CH) domain containing 3 | -0.0352722 |
| TMEM263 | transmembrane protein 263 | -0.0351891 |
| ERCC6L2 | excision repair cross-complementation group 6-like 2 | -0.0350935 |
| PGK1 | phosphoglycerate kinase 1 | -0.0348155 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.0347279 |
| PCED1B | PC-esterase domain containing 1B | -0.0345449 |
| MARCKS | myristoylated alanine-rich protein kinase C substrate | -0.0343121 |
| CAVIN1 | caveolae associated protein 1 | -0.0339012 |
| AEBP2 | AE binding protein 2 | -0.0336919 |
| ENO1 | enolase 1, (alpha) | -0.0336854 |
| BSG | basigin (Ok blood group) | -0.0333065 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.0328764 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | -0.0326017 |
| RNF213 | ring finger protein 213 | -0.0319537 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0318063 |
| UTRN | utrophin | -0.0317866 |
| DNER | delta/notch-like EGF repeat containing | -0.0307266 |
| EGR1 | early growth response 1 | -0.0306542 |
| SERPINE2 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 | -0.0303571 |
| APOLD1 | apolipoprotein L domain containing 1 | -0.0300017 |
| DPYD | dihydropyrimidine dehydrogenase | -0.0299745 |
| RPS6KA2 | ribosomal protein S6 kinase, 90kDa, polypeptide 2 | -0.0296107 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | -0.0291992 |
| SPDYA | speedy/RINGO cell cycle regulator family member A | -0.0288386 |
| TPM4 | tropomyosin 4 | -0.0286971 |
| CALM1 | calmodulin 1 (phosphorylase kinase, delta) | -0.0285694 |
| ATM | ATM serine/threonine kinase | -0.0282669 |
| RPS6 | ribosomal protein S6 | -0.0281213 |
| ATF7IP | activating transcription factor 7 interacting protein | -0.027793 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0274759 |
| IGF2 | insulin-like growth factor 2 | -0.0273312 |
| PRR16 | proline rich 16 | -0.0272719 |
| LCORL | ligand dependent nuclear receptor corepressor-like | -0.0271797 |
| SLC25A37 | solute carrier family 25 (mitochondrial iron transporter), member 37 | -0.0268174 |
| NALCN | sodium leak channel, non selective | -0.0268087 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.026723 |
| GPC6 | glypican 6 | -0.0266666 |
| CNOT2 | CCR4-NOT transcription complex, subunit 2 | -0.0264818 |
| BTG1 | B-cell translocation gene 1, anti-proliferative | -0.0263042 |
| PHF3 | PHD finger protein 3 | -0.0261124 |
| RPLP0 | ribosomal protein, large, P0 | -0.0260207 |
| RPL34 | ribosomal protein L34 | -0.0257601 |
| SRGAP1 | SLIT-ROBO Rho GTPase activating protein 1 | -0.025637 |
| ACTG1 | actin gamma 1 | -0.0253849 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.025104 |
| ANGPTL4 | angiopoietin-like 4 | -0.0250955 |
| TIAM2 | T-cell lymphoma invasion and metastasis 2 | -0.0247962 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.0245218 |
| RPS13 | ribosomal protein S13 | -0.0244957 |
| PYGL | phosphorylase, glycogen, liver | -0.0243091 |
| PRKCA | protein kinase C, alpha | -0.024214 |
| TRIM56 | tripartite motif containing 56 | -0.0237296 |
| THSD4 | thrombospondin, type I, domain containing 4 | -0.0236735 |
| WWOX | WW domain containing oxidoreductase | -0.0236706 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | -0.0236231 |
| DNAAF9 | dynein axonemal assembly factor 9 | -0.0234613 |
| ZNF638 | zinc finger protein 638 | -0.0234226 |
| CSDE1 | cold shock domain containing E1, RNA-binding | -0.0234025 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.0233626 |
| NEDD4 | neural precursor cell expressed, developmentally down-regulated 4, E3 ubiquitin protein ligase | -0.0232965 |
