| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | (R)-Verapamil (hydrochloride) perturbation in SW1417 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the (R)-Verapamil (hydrochloride)_SW1417 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| BCL2L1 | BCL2-like 1 | 0.133887 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | 0.112891 |
| RPS12 | ribosomal protein S12 | 0.0935981 |
| FTL | ferritin, light polypeptide | 0.0783759 |
| RPS3 | ribosomal protein S3 | 0.07721 |
| NEBL | nebulette | 0.0726189 |
| MYO1E | myosin IE | 0.0639523 |
| RPS4X | ribosomal protein S4, X-linked | 0.0593466 |
| RPL18 | ribosomal protein L18 | 0.0591312 |
| ABTB2 | ankyrin repeat and BTB (POZ) domain containing 2 | 0.0573006 |
| LOC102724023 | ES1 protein homolog, mitochondrial | 0.0492796 |
| CEMIP | cell migration inducing protein, hyaluronan binding | 0.0488423 |
| RPL23 | ribosomal protein L23 | 0.0484781 |
| RPL37A | ribosomal protein L37a | 0.0482951 |
| CTNNB1 | catenin (cadherin-associated protein), beta 1, 88kDa | 0.0466561 |
| NCEH1 | neutral cholesterol ester hydrolase 1 | 0.0455771 |
| RPL36 | ribosomal protein L36 | 0.0452865 |
| PMEPA1 | prostate transmembrane protein, androgen induced 1 | 0.0450461 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0444052 |
| EZR | ezrin | 0.0427567 |
| RPS19 | ribosomal protein S19 | 0.0412011 |
| PRRC2C | proline-rich coiled-coil 2C | 0.0395396 |
| RPS2 | ribosomal protein S2 | 0.0393035 |
| TOB1 | transducer of ERBB2, 1 | 0.0380104 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | 0.0378603 |
| ROCK2 | Rho-associated, coiled-coil containing protein kinase 2 | 0.0377409 |
| RPS17 | ribosomal protein S17 | 0.0376307 |
| ACTN1 | actinin, alpha 1 | 0.0369575 |
| SAMD4A | sterile alpha motif domain containing 4A | 0.0362094 |
| ZFP36L2 | ZFP36 ring finger protein-like 2 | 0.0348035 |
| RPL12 | ribosomal protein L12 | 0.0346791 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0338807 |
| HUWE1 | HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase | 0.0333203 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.0330861 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | 0.0327115 |
| NACA | nascent polypeptide-associated complex alpha subunit | 0.0321043 |
| MAN1A1 | mannosidase, alpha, class 1A, member 1 | 0.0317864 |
| YWHAG | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma | 0.0315713 |
| WWC1 | WW and C2 domain containing 1 | 0.0315509 |
| RPS8 | ribosomal protein S8 | 0.0311036 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0310922 |
| SFTPA2 | surfactant protein A2 | 0.0302521 |
| SVIL | supervillin | 0.0299268 |
| DNAJB1 | DnaJ (Hsp40) homolog, subfamily B, member 1 | 0.0294411 |
| ANKRD12 | ankyrin repeat domain 12 | 0.029143 |
| EIF3A | eukaryotic translation initiation factor 3, subunit A | 0.0289926 |
| MORF4L2 | mortality factor 4 like 2 | 0.0288289 |
| NEDD4L | neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase | 0.0287704 |
| SEPTIN9 | septin 9 | 0.0286912 |
| KRT18 | keratin 18, type I | 0.0285868 |
| PCSK5 | proprotein convertase subtilisin/kexin type 5 | 0.0283387 |
| TXNIP | thioredoxin interacting protein | 0.0283331 |
| PCLO | piccolo presynaptic cytomatrix protein | 0.0281018 |
| ARHGAP42 | Rho GTPase activating protein 42 | 0.0279113 |
| CTBP2 | C-terminal binding protein 2 | 0.0278874 |
| SET | SET nuclear proto-oncogene | 0.0278602 |
| IGF2BP3 | insulin-like growth factor 2 mRNA binding protein 3 | 0.0278144 |
| SMYD3 | SET and MYND domain containing 3 | 0.027679 |
| NDRG1 | N-myc downstream regulated 1 | 0.0275749 |
| DLGAP4 | discs, large (Drosophila) homolog-associated protein 4 | 0.0273997 |
| CREBBP | CREB binding protein | 0.0273058 |
| B2M | beta-2-microglobulin | 0.0272524 |
| STT3B | STT3B, subunit of the oligosaccharyltransferase complex (catalytic) | 0.0272395 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.0271553 |
| TJP1 | tight junction protein 1 | 0.0271018 |
| LIMA1 | LIM domain and actin binding 1 | 0.0269444 |
| EXT1 | exostosin glycosyltransferase 1 | 0.0269168 |
| RALGAPA2 | Ral GTPase activating protein, alpha subunit 2 (catalytic) | 0.0268783 |
| RPL5 | ribosomal protein L5 | 0.0267079 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0266949 |
| RACK1 | receptor for activated C kinase 1 | 0.0265875 |
| ETV6 | ets variant 6 | 0.0265214 |
| SLC12A2 | solute carrier family 12 (sodium/potassium/chloride transporter), member 2 | 0.0264858 |
| ATXN1 | ataxin 1 | 0.0263958 |
| RPS27 | ribosomal protein S27 | 0.0259779 |
| CDC42BPA | CDC42 binding protein kinase alpha (DMPK-like) | 0.025885 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0258131 |
| LIMS1 | LIM and senescent cell antigen-like domains 1 | 0.0257576 |
| ARID1B | AT rich interactive domain 1B (SWI1-like) | 0.0257421 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | 0.025739 |
| OSBPL10 | oxysterol binding protein-like 10 | 0.0256951 |
| CMIP | c-Maf inducing protein | 0.0255582 |
| GPHN | gephyrin | 0.0255176 |
| TRIM2 | tripartite motif containing 2 | 0.0253509 |
| ADAM19 | ADAM metallopeptidase domain 19 | 0.0253288 |
| EGFR | epidermal growth factor receptor | 0.0252243 |
| LRCH1 | leucine-rich repeats and calponin homology (CH) domain containing 1 | 0.0252 |
| VPS13B | vacuolar protein sorting 13 homolog B (yeast) | 0.0250483 |
| DOCK5 | dedicator of cytokinesis 5 | 0.0249257 |
| TBC1D5 | TBC1 domain family, member 5 | 0.0245535 |
| NRP1 | neuropilin 1 | 0.0244058 |
| SMAD3 | SMAD family member 3 | 0.0243749 |
| VMP1 | vacuole membrane protein 1 | 0.0243698 |
| SON | SON DNA binding protein | 0.0242932 |
| ASAP1 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 | 0.0240524 |
| NHSL1 | NHS-like 1 | 0.0237952 |
| SPTAN1 | spectrin, alpha, non-erythrocytic 1 | 0.0235477 |
| TGFA | transforming growth factor, alpha | 0.0232363 |
| SOX9 | SRY (sex determining region Y)-box 9 | 0.0231881 |
| SKAP2 | src kinase associated phosphoprotein 2 | 0.0231091 |
| Symbol | Name | Standardized Value |
|---|---|---|
| PTMA | prothymosin, alpha | -0.299527 |
| KRT8 | keratin 8, type II | -0.103121 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.0918853 |
| CCND1 | cyclin D1 | -0.0681266 |
| H1-0 | H1.0 linker histone | -0.0661635 |
| RPL35A | ribosomal protein L35a | -0.0640697 |
| PERP | PERP, TP53 apoptosis effector | -0.0608926 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0561967 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0561834 |
| TMEM123 | transmembrane protein 123 | -0.0540216 |
| S100A6 | S100 calcium binding protein A6 | -0.0493094 |
| USP3 | ubiquitin specific peptidase 3 | -0.0489455 |
| IER3 | immediate early response 3 | -0.0481842 |
| MAML2 | mastermind-like 2 (Drosophila) | -0.046793 |
| GNAS | GNAS complex locus | -0.0467231 |
| RAD21 | RAD21 homolog (S. pombe) | -0.0461974 |
| TPM4 | tropomyosin 4 | -0.0432046 |
| KDM3A | lysine (K)-specific demethylase 3A | -0.0407056 |
| AHNAK | AHNAK nucleoprotein | -0.0405306 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.0394702 |
| CTSD | cathepsin D | -0.0392898 |
| ANXA2 | annexin A2 | -0.0389349 |
| EPCAM | epithelial cell adhesion molecule | -0.0380594 |
| RHEB | Ras homolog enriched in brain | -0.0374939 |
| POTEF | POTE ankyrin domain family, member F | -0.0362259 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | -0.0345687 |
| GARS1 | glycyl-tRNA synthetase 1 | -0.0341952 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.033465 |
| TMSB4X | thymosin beta 4, X-linked | -0.0333083 |
| IRF2BP2 | interferon regulatory factor 2 binding protein 2 | -0.0332679 |
| RBM39 | RNA binding motif protein 39 | -0.0330404 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | -0.0327512 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0326776 |
| FAM3C | family with sequence similarity 3, member C | -0.03192 |
| XPO1 | exportin 1 | -0.031064 |
| NDFIP1 | Nedd4 family interacting protein 1 | -0.0309819 |
| MATR3 | matrin 3 | -0.0303648 |
| GOLGA4 | golgin A4 | -0.0294135 |
| TMSB10 | thymosin beta 10 | -0.0294104 |
| SLC25A36 | solute carrier family 25 (pyrimidine nucleotide carrier), member 36 | -0.0292937 |
| SF3B2 | splicing factor 3b, subunit 2, 145kDa | -0.028942 |
| HMGB1 | high mobility group box 1 | -0.0285407 |
| KPNB1 | karyopherin (importin) beta 1 | -0.0281455 |
| SLC38A1 | solute carrier family 38, member 1 | -0.0277816 |
| OGA | O-GlcNAcase | -0.027593 |
| EIF4A2 | eukaryotic translation initiation factor 4A2 | -0.0275272 |
| CNOT2 | CCR4-NOT transcription complex, subunit 2 | -0.0273314 |
| CCNL1 | cyclin L1 | -0.0272091 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | -0.0268981 |
| TRA2A | transformer 2 alpha homolog (Drosophila) | -0.0264426 |
| BAZ2A | bromodomain adjacent to zinc finger domain, 2A | -0.0257786 |
| RPS13 | ribosomal protein S13 | -0.0257049 |
| SETD5 | SET domain containing 5 | -0.0256753 |
| SLC20A2 | solute carrier family 20 (phosphate transporter), member 2 | -0.0255243 |
| OLA1 | Obg-like ATPase 1 | -0.0254638 |
| TCERG1 | transcription elongation regulator 1 | -0.0251046 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | -0.0249534 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0249101 |
| RSL1D1 | ribosomal L1 domain containing 1 | -0.0248641 |
| ARFGEF2 | ADP-ribosylation factor guanine nucleotide-exchange factor 2 (brefeldin A-inhibited) | -0.0247879 |
| SLC20A1 | solute carrier family 20 (phosphate transporter), member 1 | -0.0247469 |
| JUP | junction plakoglobin | -0.0246908 |
| RPS25 | ribosomal protein S25 | -0.024461 |
| CPLX2 | complexin 2 | -0.0244135 |
| PGK1 | phosphoglycerate kinase 1 | -0.0240699 |
| ATP1A4 | ATPase, Na+/K+ transporting, alpha 4 polypeptide | -0.0238462 |
| NUFIP2 | nuclear fragile X mental retardation protein interacting protein 2 | -0.0238373 |
| ZNF207 | zinc finger protein 207 | -0.0237198 |
| RPL27A | ribosomal protein L27a | -0.0235579 |
| LARS1 | leucyl-tRNA synthetase 1 | -0.022711 |
| PPP1CB | protein phosphatase 1, catalytic subunit, beta isozyme | -0.0225517 |
| PPDPF | pancreatic progenitor cell differentiation and proliferation factor | -0.022473 |
| ACTN4 | actinin, alpha 4 | -0.0224262 |
| FXR1 | fragile X mental retardation, autosomal homolog 1 | -0.0223821 |
| MARCHF6 | membrane associated ring-CH-type finger 6 | -0.0223048 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0221563 |
| RPLP0 | ribosomal protein, large, P0 | -0.0221228 |
| UGCG | UDP-glucose ceramide glucosyltransferase | -0.0219113 |
| S100A2 | S100 calcium binding protein A2 | -0.0218972 |
| VDAC1 | voltage-dependent anion channel 1 | -0.0218597 |
| HLA-A | major histocompatibility complex, class I, A | -0.0217372 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0216488 |
| CST3 | cystatin C | -0.0215784 |
| RPS21 | ribosomal protein S21 | -0.021248 |
| DEK | DEK proto-oncogene | -0.021229 |
| ADAM17 | ADAM metallopeptidase domain 17 | -0.021154 |
| ARPC2 | actin related protein 2/3 complex, subunit 2, 34kDa | -0.0210812 |
| TAF1D | TATA box binding protein (TBP)-associated factor, RNA polymerase I, D, 41kDa | -0.0210159 |
| RPS24 | ribosomal protein S24 | -0.0209709 |
| PRPF38B | pre-mRNA processing factor 38B | -0.0209487 |
| DLG1 | discs, large homolog 1 (Drosophila) | -0.020845 |
| ANKRD28 | ankyrin repeat domain 28 | -0.0207833 |
| RAB1A | RAB1A, member RAS oncogene family | -0.0205308 |
| HMGA1 | high mobility group AT-hook 1 | -0.0204769 |
| RPL34 | ribosomal protein L34 | -0.0194881 |
| COPB1 | coatomer protein complex, subunit beta 1 | -0.0194693 |
| DDX17 | DEAD (Asp-Glu-Ala-Asp) box helicase 17 | -0.0194463 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0194339 |
| ARHGAP12 | Rho GTPase activating protein 12 | -0.0192432 |
| TBL1XR1 | transducin (beta)-like 1 X-linked receptor 1 | -0.0190669 |