| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | (R)-Verapamil (hydrochloride) perturbation in SW480 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the (R)-Verapamil (hydrochloride)_SW480 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | 0.151692 |
| NKD1 | naked cuticle homolog 1 (Drosophila) | 0.13652 |
| ITPR2 | inositol 1,4,5-trisphosphate receptor, type 2 | 0.105526 |
| RPS4X | ribosomal protein S4, X-linked | 0.0824817 |
| PTPN14 | protein tyrosine phosphatase, non-receptor type 14 | 0.0788875 |
| SYT1 | synaptotagmin I | 0.0742441 |
| BCL2L1 | BCL2-like 1 | 0.0671562 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.0662831 |
| LDHA | lactate dehydrogenase A | 0.0595345 |
| TNS3 | tensin 3 | 0.0579205 |
| LOC102724023 | ES1 protein homolog, mitochondrial | 0.0550296 |
| MAN1A1 | mannosidase, alpha, class 1A, member 1 | 0.0545808 |
| DSPP | dentin sialophosphoprotein | 0.0519295 |
| ACTN1 | actinin, alpha 1 | 0.049397 |
| CTNNB1 | catenin (cadherin-associated protein), beta 1, 88kDa | 0.0491825 |
| EZR | ezrin | 0.049151 |
| KRT18 | keratin 18, type I | 0.0488815 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | 0.0477621 |
| BMP5 | bone morphogenetic protein 5 | 0.0469906 |
| LMO7 | LIM domain 7 | 0.0465874 |
| WWOX | WW domain containing oxidoreductase | 0.0456085 |
| YAP1 | Yes-associated protein 1 | 0.0452039 |
| SMURF2 | SMAD specific E3 ubiquitin protein ligase 2 | 0.0424856 |
| ROCK2 | Rho-associated, coiled-coil containing protein kinase 2 | 0.0416925 |
| AOPEP | aminopeptidase O (putative) | 0.041192 |
| PCLO | piccolo presynaptic cytomatrix protein | 0.0403635 |
| SEPTIN9 | septin 9 | 0.0397778 |
| ZBTB38 | zinc finger and BTB domain containing 38 | 0.0394346 |
| PRRC2C | proline-rich coiled-coil 2C | 0.036196 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.0360343 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0360202 |
| FOXP1 | forkhead box P1 | 0.0353663 |
| SLC12A2 | solute carrier family 12 (sodium/potassium/chloride transporter), member 2 | 0.0351055 |
| RPS12 | ribosomal protein S12 | 0.0350046 |
| GLI3 | GLI family zinc finger 3 | 0.0347231 |
| B4GALT5 | UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 5 | 0.0346877 |
| EFNB2 | ephrin-B2 | 0.0339465 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0330689 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | 0.0327508 |
| SPATA13 | spermatogenesis associated 13 | 0.0321312 |
| TJP1 | tight junction protein 1 | 0.0318036 |
| EGR1 | early growth response 1 | 0.031444 |
| PUM1 | pumilio RNA-binding family member 1 | 0.0310152 |
| ITPRID2 | ITPR interacting domain containing 2 | 0.0309802 |
| SVIL | supervillin | 0.0304879 |
| ACTR3 | ARP3 actin-related protein 3 homolog (yeast) | 0.0304021 |
| FUS | FUS RNA binding protein | 0.0299983 |
| MT2A | metallothionein 2A | 0.0299263 |
| TGFBR2 | transforming growth factor, beta receptor II (70/80kDa) | 0.0295879 |
| DOCK5 | dedicator of cytokinesis 5 | 0.0292955 |
| SPIDR | scaffolding protein involved in DNA repair | 0.0291765 |
| NONO | non-POU domain containing, octamer-binding | 0.0288298 |
| MKI67 | marker of proliferation Ki-67 | 0.02854 |
| SNTB1 | syntrophin, beta 1 (dystrophin-associated protein A1, 59kDa, basic component 1) | 0.0285365 |
| RACK1 | receptor for activated C kinase 1 | 0.0284699 |
| CENPF | centromere protein F, 350/400kDa | 0.0279533 |
| RNF43 | ring finger protein 43 | 0.0279484 |
| MBNL1 | muscleblind-like splicing regulator 1 | 0.0279305 |
| RPS3 | ribosomal protein S3 | 0.0274414 |
| ARHGAP42 | Rho GTPase activating protein 42 | 0.0271377 |
| PCM1 | pericentriolar material 1 | 0.0266458 |
| CTDSPL | CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase-like | 0.0264571 |
| CDC42BPA | CDC42 binding protein kinase alpha (DMPK-like) | 0.0261233 |
| TIAM1 | T-cell lymphoma invasion and metastasis 1 | 0.0260896 |
| WNK1 | WNK lysine deficient protein kinase 1 | 0.026063 |
| EHBP1 | EH domain binding protein 1 | 0.0255191 |
| TEAD1 | TEA domain family member 1 (SV40 transcriptional enhancer factor) | 0.0254512 |
| YWHAG | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma | 0.0253508 |
| PDLIM5 | PDZ and LIM domain 5 | 0.0250132 |
| MCC | mutated in colorectal cancers | 0.024828 |
| KLF12 | Kruppel-like factor 12 | 0.0247969 |
| SYK | spleen tyrosine kinase | 0.0247142 |
| HUWE1 | HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase | 0.024431 |
| NCEH1 | neutral cholesterol ester hydrolase 1 | 0.024366 |
| BCAS3 | breast carcinoma amplified sequence 3 | 0.0242369 |
| EGFR | epidermal growth factor receptor | 0.0241862 |
| AGPAT5 | 1-acylglycerol-3-phosphate O-acyltransferase 5 | 0.0240363 |
| TSC22D1 | TSC22 domain family, member 1 | 0.0237889 |
| VMP1 | vacuole membrane protein 1 | 0.0230357 |
| ARGLU1 | arginine and glutamate rich 1 | 0.0229856 |
| SMAD3 | SMAD family member 3 | 0.0229785 |
| PRELID2 | PRELI domain containing 2 | 0.0227325 |
| CTNND1 | catenin (cadherin-associated protein), delta 1 | 0.0226381 |
| ENO1 | enolase 1, (alpha) | 0.0224787 |
| CSNK1A1 | casein kinase 1, alpha 1 | 0.0222545 |
| MAGI3 | membrane associated guanylate kinase, WW and PDZ domain containing 3 | 0.022241 |
| LRP6 | low density lipoprotein receptor-related protein 6 | 0.0221322 |
| NEBL | nebulette | 0.0220908 |
| CALM1 | calmodulin 1 (phosphorylase kinase, delta) | 0.0218073 |
| UCHL3 | ubiquitin carboxyl-terminal esterase L3 (ubiquitin thiolesterase) | 0.0214672 |
| ASAP1 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 | 0.0212873 |
| OXR1 | oxidation resistance 1 | 0.0212521 |
| CREBBP | CREB binding protein | 0.0210694 |
| PRKDC | protein kinase, DNA-activated, catalytic polypeptide | 0.0210335 |
| ANKRD1 | ankyrin repeat domain 1 (cardiac muscle) | 0.0209286 |
| STAT3 | signal transducer and activator of transcription 3 (acute-phase response factor) | 0.0208752 |
| SMYD3 | SET and MYND domain containing 3 | 0.0208646 |
| DST | dystonin | 0.0208115 |
| EXOC6B | exocyst complex component 6B | 0.0206154 |
| CUL3 | cullin 3 | 0.0204671 |
| Symbol | Name | Standardized Value |
|---|---|---|
| ROBO2 | roundabout, axon guidance receptor, homolog 2 (Drosophila) | -0.201567 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | -0.146134 |
| CDH13 | cadherin 13 | -0.129556 |
| ANO1 | anoctamin 1, calcium activated chloride channel | -0.118542 |
| SLC5A3 | solute carrier family 5 (sodium/myo-inositol cotransporter), member 3 | -0.102983 |
| SDK1 | sidekick cell adhesion molecule 1 | -0.089154 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | -0.0805507 |
| PTMA | prothymosin, alpha | -0.0793045 |
| RPS6 | ribosomal protein S6 | -0.077155 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0755196 |
| NAV2 | neuron navigator 2 | -0.0738425 |
| ESYT2 | extended synaptotagmin-like protein 2 | -0.0692134 |
| KRT8 | keratin 8, type II | -0.0676847 |
| SKAP1 | src kinase associated phosphoprotein 1 | -0.0659472 |
| RPL35A | ribosomal protein L35a | -0.0652137 |
| MRPS6 | mitochondrial ribosomal protein S6 | -0.0651349 |
| SLC2A3 | solute carrier family 2 (facilitated glucose transporter), member 3 | -0.0648449 |
| SLC2A1 | solute carrier family 2 (facilitated glucose transporter), member 1 | -0.0640859 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0626285 |
| DDX17 | DEAD (Asp-Glu-Ala-Asp) box helicase 17 | -0.0582621 |
| PPFIBP1 | PTPRF interacting protein, binding protein 1 (liprin beta 1) | -0.0576921 |
| GOLGA4 | golgin A4 | -0.0562325 |
| CCND1 | cyclin D1 | -0.0544749 |
| ANXA2 | annexin A2 | -0.0541869 |
| HMGA1 | high mobility group AT-hook 1 | -0.0519641 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | -0.051886 |
| PTPRN2 | protein tyrosine phosphatase, receptor type, N polypeptide 2 | -0.051181 |
| VOPP1 | vesicular, overexpressed in cancer, prosurvival protein 1 | -0.0507989 |
| ACTG1 | actin gamma 1 | -0.0499463 |
| CANX | calnexin | -0.0498853 |
| GLG1 | golgi glycoprotein 1 | -0.0491638 |
| AHNAK | AHNAK nucleoprotein | -0.0485821 |
| NUFIP2 | nuclear fragile X mental retardation protein interacting protein 2 | -0.0484658 |
| MAML2 | mastermind-like 2 (Drosophila) | -0.0467797 |
| BACE2 | beta-site APP-cleaving enzyme 2 | -0.0459565 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0458841 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | -0.0456833 |
| TMSB10 | thymosin beta 10 | -0.0436398 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0434881 |
| ITGB4 | integrin, beta 4 | -0.0431546 |
| CDKAL1 | CDK5 regulatory subunit associated protein 1-like 1 | -0.0418749 |
| POLR2A | polymerase (RNA) II (DNA directed) polypeptide A, 220kDa | -0.041458 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | -0.0411986 |
| TPM4 | tropomyosin 4 | -0.0399212 |
| PDGFA | platelet-derived growth factor alpha polypeptide | -0.0395154 |
| PERP | PERP, TP53 apoptosis effector | -0.0391721 |
| MYOF | myoferlin | -0.0389781 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.0384928 |
| TMSB4X | thymosin beta 4, X-linked | -0.0383489 |
| PFN1 | profilin 1 | -0.0380579 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.0377652 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.0366401 |
| ETNK1 | ethanolamine kinase 1 | -0.0355317 |
| GNPDA1 | glucosamine-6-phosphate deaminase 1 | -0.0354539 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.0352549 |
| CBX5 | chromobox homolog 5 | -0.0348843 |
| FLNB | filamin B, beta | -0.0348652 |
| ZCCHC7 | zinc finger, CCHC domain containing 7 | -0.0347701 |
| ASPH | aspartate beta-hydroxylase | -0.0345681 |
| ARF4 | ADP-ribosylation factor 4 | -0.0331951 |
| POTEF | POTE ankyrin domain family, member F | -0.0329419 |
| PGK1 | phosphoglycerate kinase 1 | -0.0328769 |
| PKM | pyruvate kinase, muscle | -0.0328647 |
| FRMD5 | FERM domain containing 5 | -0.0319746 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0317617 |
| EEF1G | eukaryotic translation elongation factor 1 gamma | -0.0297325 |
| BAZ2A | bromodomain adjacent to zinc finger domain, 2A | -0.0290237 |
| H1-0 | H1.0 linker histone | -0.0284785 |
| SEC31A | SEC31 homolog A (S. cerevisiae) | -0.0284041 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | -0.0280485 |
| KIZ | kizuna centrosomal protein | -0.0277612 |
| SETD5 | SET domain containing 5 | -0.0268924 |
| LRPPRC | leucine-rich pentatricopeptide repeat containing | -0.0267534 |
| SLC1A5 | solute carrier family 1 (neutral amino acid transporter), member 5 | -0.0266404 |
| KMT2C | lysine (K)-specific methyltransferase 2C | -0.0265333 |
| NKTR | natural killer cell triggering receptor | -0.0261293 |
| PIK3C2A | phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 alpha | -0.0257492 |
| ITGA6 | integrin, alpha 6 | -0.0256111 |
| SPDYA | speedy/RINGO cell cycle regulator family member A | -0.025479 |
| TIMP2 | TIMP metallopeptidase inhibitor 2 | -0.0254177 |
| TNIK | TRAF2 and NCK interacting kinase | -0.0253738 |
| SF3B2 | splicing factor 3b, subunit 2, 145kDa | -0.024734 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0245694 |
| GMDS | GDP-mannose 4,6-dehydratase | -0.0242979 |
| EEPD1 | endonuclease/exonuclease/phosphatase family domain containing 1 | -0.0242326 |
| GRIN2B | glutamate receptor, ionotropic, N-methyl D-aspartate 2B | -0.0241549 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.0241129 |
| RHOA | ras homolog family member A | -0.0238116 |
| HM13 | histocompatibility (minor) 13 | -0.0235732 |
| RBM39 | RNA binding motif protein 39 | -0.0235009 |
| EIF2S3 | eukaryotic translation initiation factor 2, subunit 3 gamma, 52kDa | -0.0234455 |
| COG5 | component of oligomeric golgi complex 5 | -0.023195 |
| KDM4C | lysine (K)-specific demethylase 4C | -0.0230036 |
| COPA | coatomer protein complex, subunit alpha | -0.0228735 |
| RPLP1 | ribosomal protein, large, P1 | -0.0228578 |
| VIM | vimentin | -0.0228554 |
| NCOR2 | nuclear receptor corepressor 2 | -0.0228187 |
| FNDC3B | fibronectin type III domain containing 3B | -0.0226858 |
| RBM25 | RNA binding motif protein 25 | -0.0225354 |
| COPB1 | coatomer protein complex, subunit beta 1 | -0.0223058 |
