| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | (R)-Verapamil (hydrochloride) perturbation in hTERT-HPNE cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the (R)-Verapamil (hydrochloride)_hTERT-HPNE drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| INHBA | inhibin, beta A | 0.142741 |
| EXT1 | exostosin glycosyltransferase 1 | 0.111782 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.0932614 |
| HMGA2 | high mobility group AT-hook 2 | 0.0925336 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | 0.085556 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | 0.0812051 |
| NALF1 | NALCN channel auxiliary factor 1 | 0.0753988 |
| PALM2AKAP2 | PALM2 and AKAP2 fusion | 0.0657563 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.0651132 |
| PDE3A | phosphodiesterase 3A, cGMP-inhibited | 0.0645913 |
| CD44 | CD44 molecule (Indian blood group) | 0.0622245 |
| FN1 | fibronectin 1 | 0.0600825 |
| LAMC1 | laminin, gamma 1 (formerly LAMB2) | 0.0596729 |
| ASPH | aspartate beta-hydroxylase | 0.0578471 |
| EGFR | epidermal growth factor receptor | 0.0575934 |
| MYO10 | myosin X | 0.0540412 |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) | 0.0518047 |
| GLIS3 | GLIS family zinc finger 3 | 0.0492579 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.0458317 |
| TIMP1 | TIMP metallopeptidase inhibitor 1 | 0.0445265 |
| FRMD4A | FERM domain containing 4A | 0.0427407 |
| PDLIM5 | PDZ and LIM domain 5 | 0.0426206 |
| SMAD3 | SMAD family member 3 | 0.0420661 |
| WNT5A | wingless-type MMTV integration site family, member 5A | 0.0418949 |
| NAV1 | neuron navigator 1 | 0.0415064 |
| NOTCH2 | notch 2 | 0.0400007 |
| SPRED2 | sprouty-related, EVH1 domain containing 2 | 0.038343 |
| ANKRD28 | ankyrin repeat domain 28 | 0.0381556 |
| SIPA1L1 | signal-induced proliferation-associated 1 like 1 | 0.0371174 |
| RFX8 | RFX family member 8, lacking RFX DNA binding domain | 0.0347485 |
| BPTF | bromodomain PHD finger transcription factor | 0.0343659 |
| TSC22D1 | TSC22 domain family, member 1 | 0.0343316 |
| LDHA | lactate dehydrogenase A | 0.0341463 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.0338988 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0338104 |
| ARHGAP24 | Rho GTPase activating protein 24 | 0.0332698 |
| STC1 | stanniocalcin 1 | 0.0328219 |
| HIPK2 | homeodomain interacting protein kinase 2 | 0.0319843 |
| VCL | vinculin | 0.0318842 |
| PRRC2C | proline-rich coiled-coil 2C | 0.0312643 |
| APP | amyloid beta (A4) precursor protein | 0.0312569 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | 0.0312485 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0310576 |
| PPFIBP1 | PTPRF interacting protein, binding protein 1 (liprin beta 1) | 0.0310163 |
| ACTN1 | actinin, alpha 1 | 0.0306768 |
| FNDC3A | fibronectin type III domain containing 3A | 0.0305467 |
| PHC2 | polyhomeotic homolog 2 (Drosophila) | 0.0304619 |
| USP34 | ubiquitin specific peptidase 34 | 0.0294994 |
| EGR1 | early growth response 1 | 0.0290093 |
| ARHGAP31 | Rho GTPase activating protein 31 | 0.0289963 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0286536 |
| ZBTB38 | zinc finger and BTB domain containing 38 | 0.0278165 |
| IGFBP7 | insulin-like growth factor binding protein 7 | 0.0277869 |
| SLC38A2 | solute carrier family 38, member 2 | 0.0274945 |
| WWTR1 | WW domain containing transcription regulator 1 | 0.0273899 |
| RUNX1 | runt-related transcription factor 1 | 0.0272792 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | 0.0270392 |
| TGFBI | transforming growth factor, beta-induced, 68kDa | 0.026853 |
| MAML2 | mastermind-like 2 (Drosophila) | 0.0265697 |
| RAB31 | RAB31, member RAS oncogene family | 0.0262586 |
| KPNA4 | karyopherin alpha 4 (importin alpha 3) | 0.0262577 |
| SPRED1 | sprouty-related, EVH1 domain containing 1 | 0.0253111 |
| RPS4X | ribosomal protein S4, X-linked | 0.0250718 |
| JARID2 | jumonji, AT rich interactive domain 2 | 0.0245142 |
| MED13L | mediator complex subunit 13-like | 0.0243191 |
| SLC4A7 | solute carrier family 4, sodium bicarbonate cotransporter, member 7 | 0.0242486 |
| NRP1 | neuropilin 1 | 0.0239706 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0235379 |
| LTBP1 | latent transforming growth factor beta binding protein 1 | 0.023418 |
| EPAS1 | endothelial PAS domain protein 1 | 0.0232686 |
| LOXL2 | lysyl oxidase-like 2 | 0.0229609 |
| NAA16 | N(alpha)-acetyltransferase 16, NatA auxiliary subunit | 0.0229027 |
| NUMB | numb homolog (Drosophila) | 0.0228729 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0227311 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | 0.0227229 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0226377 |
| JAG1 | jagged 1 | 0.0226042 |
| KLF12 | Kruppel-like factor 12 | 0.0224358 |
| FOXP1 | forkhead box P1 | 0.0224163 |
| MT2A | metallothionein 2A | 0.0223701 |
| TBC1D5 | TBC1 domain family, member 5 | 0.0221879 |
| NABP1 | nucleic acid binding protein 1 | 0.0220095 |
| AMOTL1 | angiomotin like 1 | 0.022001 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | 0.0218501 |
| FLNA | filamin A, alpha | 0.0215662 |
| EIF4G2 | eukaryotic translation initiation factor 4 gamma, 2 | 0.02124 |
| FLNB | filamin B, beta | 0.0211181 |
| FERMT2 | fermitin family member 2 | 0.0209978 |
| RPS12 | ribosomal protein S12 | 0.0209883 |
| RPS3 | ribosomal protein S3 | 0.0206474 |
| ANTXR2 | anthrax toxin receptor 2 | 0.0205015 |
| ATP2B4 | ATPase, Ca++ transporting, plasma membrane 4 | 0.0204456 |
| JMJD1C | jumonji domain containing 1C | 0.0203771 |
| RERE | arginine-glutamic acid dipeptide (RE) repeats | 0.0203394 |
| FBXL7 | F-box and leucine-rich repeat protein 7 | 0.0200642 |
| CD59 | CD59 molecule, complement regulatory protein | 0.020037 |
| WLS | wntless Wnt ligand secretion mediator | 0.0200123 |
| LHFPL2 | lipoma HMGIC fusion partner-like 2 | 0.019984 |
| ID3 | inhibitor of DNA binding 3, dominant negative helix-loop-helix protein | 0.0196325 |
| SEPTIN11 | septin 11 | 0.0195103 |
| Symbol | Name | Standardized Value |
|---|---|---|
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.2419 |
| VIM | vimentin | -0.202885 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.143441 |
| COL6A2 | collagen, type VI, alpha 2 | -0.135168 |
| PRKG1 | protein kinase, cGMP-dependent, type I | -0.115508 |
| MMP1 | matrix metallopeptidase 1 | -0.107089 |
| ADAMTS6 | ADAM metallopeptidase with thrombospondin type 1 motif, 6 | -0.095741 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0922526 |
| COL6A3 | collagen, type VI, alpha 3 | -0.0919619 |
| MMP12 | matrix metallopeptidase 12 | -0.0871125 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0852307 |
| OXR1 | oxidation resistance 1 | -0.0816709 |
| GOLGA4 | golgin A4 | -0.0807167 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0766792 |
| COL6A1 | collagen, type VI, alpha 1 | -0.0683879 |
| FAM13A | family with sequence similarity 13, member A | -0.0659215 |
| ROBO2 | roundabout, axon guidance receptor, homolog 2 (Drosophila) | -0.0655247 |
| ADM | adrenomedullin | -0.0650401 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | -0.0639061 |
| FRMPD4 | FERM and PDZ domain containing 4 | -0.0622764 |
| TMSB10 | thymosin beta 10 | -0.0601172 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | -0.0592089 |
| ADAMTS12 | ADAM metallopeptidase with thrombospondin type 1 motif, 12 | -0.0555353 |
| MMAB | methylmalonic aciduria (cobalamin deficiency) cblB type | -0.0542537 |
| CAVIN1 | caveolae associated protein 1 | -0.054022 |
| COL1A1 | collagen, type I, alpha 1 | -0.0492655 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.0491148 |
| REV3L | REV3-like, polymerase (DNA directed), zeta, catalytic subunit | -0.0481093 |
| CDH13 | cadherin 13 | -0.0479544 |
| PAPPA | pregnancy-associated plasma protein A, pappalysin 1 | -0.0478616 |
| CANX | calnexin | -0.044282 |
| ZCCHC7 | zinc finger, CCHC domain containing 7 | -0.0438922 |
| TTC3 | tetratricopeptide repeat domain 3 | -0.0410104 |
| AHNAK | AHNAK nucleoprotein | -0.0404733 |
| SLC8A1 | solute carrier family 8 (sodium/calcium exchanger), member 1 | -0.040462 |
| LMAN1 | lectin, mannose-binding, 1 | -0.038895 |
| ADAM9 | ADAM metallopeptidase domain 9 | -0.0382463 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | -0.0379903 |
| ADGRB3 | adhesion G protein-coupled receptor B3 | -0.0378875 |
| ATP13A3 | ATPase type 13A3 | -0.0378179 |
| HELZ | helicase with zinc finger | -0.0372964 |
| TMEM165 | transmembrane protein 165 | -0.0365306 |
| GREM1 | gremlin 1, DAN family BMP antagonist | -0.0364402 |
| PGK1 | phosphoglycerate kinase 1 | -0.0349997 |
| PRRX1 | paired related homeobox 1 | -0.0348958 |
| IARS1 | isoleucyl-tRNA synthetase 1 | -0.0348397 |
| SEC24D | SEC24 family member D | -0.0346987 |
| TIMP2 | TIMP metallopeptidase inhibitor 2 | -0.0343929 |
| HILPDA | hypoxia inducible lipid droplet-associated | -0.0341246 |
| USP3 | ubiquitin specific peptidase 3 | -0.0331036 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | -0.0329668 |
| FTL | ferritin, light polypeptide | -0.0328671 |
| SRP54 | signal recognition particle 54kDa | -0.0327902 |
| HDLBP | high density lipoprotein binding protein | -0.0327587 |
| ZNF292 | zinc finger protein 292 | -0.032244 |
| FGFR1 | fibroblast growth factor receptor 1 | -0.032187 |
| AFF3 | AF4/FMR2 family, member 3 | -0.0317827 |
| TPM4 | tropomyosin 4 | -0.0309863 |
| WSB1 | WD repeat and SOCS box containing 1 | -0.0308281 |
| CALR | calreticulin | -0.0296323 |
| SEL1L | sel-1 suppressor of lin-12-like (C. elegans) | -0.0295757 |
| OGA | O-GlcNAcase | -0.0295385 |
| ITGA1 | integrin, alpha 1 | -0.0290852 |
| DDR2 | discoidin domain receptor tyrosine kinase 2 | -0.0287775 |
| SEC61A1 | Sec61 alpha 1 subunit (S. cerevisiae) | -0.0286085 |
| NGLY1 | N-glycanase 1 | -0.0285535 |
| DST | dystonin | -0.0278849 |
| RAB1A | RAB1A, member RAS oncogene family | -0.0277074 |
| TMEM263 | transmembrane protein 263 | -0.0270656 |
| INSIG1 | insulin induced gene 1 | -0.0267861 |
| ASAP1 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 | -0.0265739 |
| GARS1 | glycyl-tRNA synthetase 1 | -0.0264633 |
| ESYT2 | extended synaptotagmin-like protein 2 | -0.0263242 |
| AP3B1 | adaptor-related protein complex 3, beta 1 subunit | -0.0259398 |
| MYH9 | myosin, heavy chain 9, non-muscle | -0.025918 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0258132 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.0254834 |
| LCORL | ligand dependent nuclear receptor corepressor-like | -0.0254109 |
| NBAS | neuroblastoma amplified sequence | -0.0252641 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.0250245 |
| UGCG | UDP-glucose ceramide glucosyltransferase | -0.0247514 |
| P4HA2 | prolyl 4-hydroxylase, alpha polypeptide II | -0.0245745 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | -0.0243816 |
| ENO2 | enolase 2 (gamma, neuronal) | -0.0241991 |
| FBN1 | fibrillin 1 | -0.024052 |
| PDIA6 | protein disulfide isomerase family A, member 6 | -0.0240355 |
| NCKAP5 | NCK-associated protein 5 | -0.0238384 |
| TBC1D23 | TBC1 domain family, member 23 | -0.0237597 |
| VCAN | versican | -0.0235866 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | -0.0235267 |
| DNAJC3 | DnaJ (Hsp40) homolog, subfamily C, member 3 | -0.0234568 |
| NBEAL1 | neurobeachin-like 1 | -0.023434 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | -0.0231378 |
| SETD5 | SET domain containing 5 | -0.0230959 |
| S100A6 | S100 calcium binding protein A6 | -0.0228605 |
| HM13 | histocompatibility (minor) 13 | -0.022492 |
| RPS6 | ribosomal protein S6 | -0.0223723 |
| SLC2A1 | solute carrier family 2 (facilitated glucose transporter), member 1 | -0.02225 |
| LGALS1 | lectin, galactoside-binding, soluble, 1 | -0.0218564 |
| SOD2 | superoxide dismutase 2, mitochondrial | -0.0217206 |
