| Dataset | DeepCoverMOA Drug Mechanisms of Action |
| Category | proteomics |
| Type | drug perturbation |
| External Link | https://pubchem.ncbi.nlm.nih.gov/compound/688095 |
| Similar Terms | |
| Downloads & Tools |
199 proteins with high or low expression in (S)-(-)-Pindolol relative to other proteins from the DeepCoverMOA Drug Mechanisms of Action dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| CUBN | cubilin (intrinsic factor-cobalamin receptor) | 1.38 |
| THAP9 | THAP domain containing 9 | 1.12 |
| SNED1 | sushi, nidogen and EGF-like domains 1 | 1.04 |
| ZNF169 | zinc finger protein 169 | 1.02 |
| SH3RF2 | SH3 domain containing ring finger 2 | 0.94 |
| NR1D2 | nuclear receptor subfamily 1, group D, member 2 | 0.86 |
| LYPD3 | LY6/PLAUR domain containing 3 | 0.86 |
| KMT2B | lysine (K)-specific methyltransferase 2B | 0.84 |
| ADGRV1 | adhesion G protein-coupled receptor V1 | 0.7 |
| SLC41A3 | solute carrier family 41, member 3 | 0.65 |
| FZD3 | frizzled class receptor 3 | 0.65 |
| TM7SF2 | transmembrane 7 superfamily member 2 | 0.61 |
| PTGS1 | prostaglandin-endoperoxide synthase 1 (prostaglandin G/H synthase and cyclooxygenase) | 0.61 |
| TTLL4 | tubulin tyrosine ligase-like family member 4 | 0.57 |
| PPP4R4 | protein phosphatase 4, regulatory subunit 4 | 0.54 |
| GALNT5 | polypeptide N-acetylgalactosaminyltransferase 5 | 0.53 |
| ZNF692 | zinc finger protein 692 | 0.52 |
| YPEL5 | yippee-like 5 (Drosophila) | 0.51 |
| HMCN1 | hemicentin 1 | 0.51 |
| REX1BD | required for excision 1-B domain containing | 0.49 |
| ADGRG6 | adhesion G protein-coupled receptor G6 | 0.48 |
| STON2 | stonin 2 | 0.45 |
| AASDH | aminoadipate-semialdehyde dehydrogenase | 0.44 |
| NOL3 | nucleolar protein 3 (apoptosis repressor with CARD domain) | 0.43 |
| SLC6A6 | solute carrier family 6 (neurotransmitter transporter), member 6 | 0.42 |
| DDIT4 | DNA-damage-inducible transcript 4 | 0.42 |
| TRPM7 | transient receptor potential cation channel, subfamily M, member 7 | 0.41 |
| ZNF2 | zinc finger protein 2 | 0.41 |
| ZDHHC3 | zinc finger, DHHC-type containing 3 | 0.39 |
| ALG12 | ALG12, alpha-1,6-mannosyltransferase | 0.39 |
| CA8 | carbonic anhydrase VIII | 0.39 |
| ABITRAM | actin binding transcription modulator | 0.38 |
| MCF2L | MCF.2 cell line derived transforming sequence-like | 0.38 |
| RAB36 | RAB36, member RAS oncogene family | 0.37 |
| BOD1 | biorientation of chromosomes in cell division 1 | 0.37 |
| TP73 | tumor protein p73 | 0.36 |
| ALOXE3 | arachidonate lipoxygenase 3 | 0.35 |
| SLC11A2 | solute carrier family 11 (proton-coupled divalent metal ion transporter), member 2 | 0.35 |
| ZNF263 | zinc finger protein 263 | 0.34 |
| XBP1 | X-box binding protein 1 | 0.34 |
| NAA38 | N(alpha)-acetyltransferase 38, NatC auxiliary subunit | 0.33 |
| TFAP2E | transcription factor AP-2 epsilon (activating enhancer binding protein 2 epsilon) | 0.33 |
| KCNN4 | potassium channel, calcium activated intermediate/small conductance subfamily N alpha, member 4 | 0.33 |
| STK35 | serine/threonine kinase 35 | 0.32 |
| CBLL1 | Cbl proto-oncogene-like 1, E3 ubiquitin protein ligase | 0.32 |
| CYBA | cytochrome b-245, alpha polypeptide | 0.32 |
| TRAF3 | TNF receptor-associated factor 3 | 0.32 |
| PLEKHA7 | pleckstrin homology domain containing, family A member 7 | 0.31 |
| PCNX1 | pecanex 1 | 0.3 |
| MCOLN2 | mucolipin 2 | 0.3 |
| ANKS6 | ankyrin repeat and sterile alpha motif domain containing 6 | 0.3 |
| RND3 | Rho family GTPase 3 | 0.3 |
| SELENOK | selenoprotein K | 0.3 |
| CPLANE1 | ciliogenesis and planar polarity effector complex subunit 1 | 0.3 |
| WDR89 | WD repeat domain 89 | 0.3 |
| PCTP | phosphatidylcholine transfer protein | 0.29 |
| AP5B1 | adaptor-related protein complex 5, beta 1 subunit | 0.29 |
| ZNF430 | zinc finger protein 430 | 0.28 |
| TIMM8B | translocase of inner mitochondrial membrane 8 homolog B (yeast) | 0.28 |
| ONECUT3 | one cut homeobox 3 | 0.28 |
| ABHD4 | abhydrolase domain containing 4 | 0.28 |
| SGSM1 | small G protein signaling modulator 1 | 0.27 |
| ENTPD4 | ectonucleoside triphosphate diphosphohydrolase 4 | 0.27 |
| ATF7 | activating transcription factor 7 | 0.27 |
| LRRC7 | leucine rich repeat containing 7 | 0.27 |
| NPNT | nephronectin | 0.26 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | 0.26 |
| MZT2B | mitotic spindle organizing protein 2B | 0.26 |
| TBC1D13 | TBC1 domain family, member 13 | 0.26 |
| RTN4RL2 | reticulon 4 receptor-like 2 | 0.26 |
| PARPBP | PARP1 binding protein | 0.26 |
| IDUA | iduronidase, alpha-L- | 0.26 |
| MON1B | MON1 secretory trafficking family member B | 0.26 |
| OSMR | oncostatin M receptor | 0.26 |
| SPICE1 | spindle and centriole associated protein 1 | 0.26 |
| TNNC2 | troponin C type 2 (fast) | 0.25 |
| RCE1 | Ras converting CAAX endopeptidase 1 | 0.25 |
| H4C1 | H4 clustered histone 1 | 0.25 |
| AGAP2 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 2 | 0.25 |
| SOCS2 | suppressor of cytokine signaling 2 | 0.25 |
| HEXD | hexosaminidase D | 0.25 |
| PXMP2 | peroxisomal membrane protein 2, 22kDa | 0.25 |
| CREBZF | CREB/ATF bZIP transcription factor | 0.25 |
| ZNF566 | zinc finger protein 566 | 0.25 |
| POTEE | POTE ankyrin domain family, member E | 0.25 |
| NR2C1 | nuclear receptor subfamily 2, group C, member 1 | 0.25 |
| PMF1 | polyamine-modulated factor 1 | 0.25 |
| VMA21 | VMA21 vacuolar H+-ATPase homolog (S. cerevisiae) | 0.25 |
| BLOC1S4 | biogenesis of lysosomal organelles complex-1, subunit 4, cappuccino | 0.25 |
| MTHFR | methylenetetrahydrofolate reductase (NAD(P)H) | 0.24 |
| PGGT1B | protein geranylgeranyltransferase type I, beta subunit | 0.24 |
| SLC25A33 | solute carrier family 25 (pyrimidine nucleotide carrier), member 33 | 0.24 |
| EPHA5 | EPH receptor A5 | 0.24 |
| PHF13 | PHD finger protein 13 | 0.24 |
| MRPS18C | mitochondrial ribosomal protein S18C | 0.24 |
| AP1S2 | adaptor-related protein complex 1, sigma 2 subunit | 0.24 |
| PRSS12 | protease, serine, 12 (neurotrypsin, motopsin) | 0.24 |
| SHC4 | SHC (Src homology 2 domain containing) family, member 4 | 0.24 |
| ERCC6L2 | excision repair cross-complementation group 6-like 2 | 0.24 |
| SLC41A2 | solute carrier family 41 (magnesium transporter), member 2 | 0.24 |
| Symbol | Name | Standardized Value |
|---|---|---|
| TRIM35 | tripartite motif containing 35 | -0.93 |
| NCKAP5L | NCK-associated protein 5-like | -0.75 |
| ABHD2 | abhydrolase domain containing 2 | -0.74 |
| ADCK5 | aarF domain containing kinase 5 | -0.69 |
| SIGIRR | single immunoglobulin and toll-interleukin 1 receptor (TIR) domain | -0.67 |
| ICOSLG | inducible T-cell co-stimulator ligand | -0.67 |
| FAM185A | family with sequence similarity 185, member A | -0.67 |
| HSP90AB4P | heat shock protein 90kDa alpha (cytosolic), class B member 4, pseudogene | -0.55 |
| AKNA | AT-hook transcription factor | -0.51 |
| FN1 | fibronectin 1 | -0.48 |
| ZFPM1 | zinc finger protein, FOG family member 1 | -0.48 |
| ZC3H6 | zinc finger CCCH-type containing 6 | -0.45 |
| ZNF200 | zinc finger protein 200 | -0.44 |
| MYL3 | myosin, light chain 3, alkali; ventricular, skeletal, slow | -0.41 |
| B3GNTL1 | UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase-like 1 | -0.4 |
| PPARD | peroxisome proliferator-activated receptor delta | -0.39 |
| B9D1 | B9 protein domain 1 | -0.39 |
| MYPOP | Myb-related transcription factor, partner of profilin | -0.38 |
| HEMK1 | HemK methyltransferase family member 1 | -0.37 |
| SBNO2 | strawberry notch homolog 2 (Drosophila) | -0.37 |
| CORO2B | coronin, actin binding protein, 2B | -0.36 |
| HIST2H2AA3 | histone cluster 2, H2aa3 | -0.36 |
| ZMAT5 | zinc finger, matrin-type 5 | -0.35 |
| CNTRL | centriolin | -0.34 |
| KANK3 | KN motif and ankyrin repeat domains 3 | -0.34 |
| ADAMTS7 | ADAM metallopeptidase with thrombospondin type 1 motif, 7 | -0.34 |
| CMTM4 | CKLF-like MARVEL transmembrane domain containing 4 | -0.34 |
| SELENOM | selenoprotein M | -0.34 |
| FABP6 | fatty acid binding protein 6, ileal | -0.34 |
| LYSMD1 | LysM, putative peptidoglycan-binding, domain containing 1 | -0.33 |
| EPHB3 | EPH receptor B3 | -0.33 |
| ZCCHC24 | zinc finger, CCHC domain containing 24 | -0.33 |
| CYTH3 | cytohesin 3 | -0.32 |
| MCTS2P | malignant T cell amplified sequence 2, pseudogene | -0.32 |
| ATP8B2 | ATPase, aminophospholipid transporter, class I, type 8B, member 2 | -0.31 |
| LSM5 | LSM5 homolog, U6 small nuclear RNA associated (S. cerevisiae) | -0.31 |
| MYO9A | myosin IXA | -0.3 |
| TESC | tescalcin | -0.3 |
| MARK4 | MAP/microtubule affinity-regulating kinase 4 | -0.3 |
| ABCB4 | ATP-binding cassette, sub-family B (MDR/TAP), member 4 | -0.3 |
| ISL2 | ISL LIM homeobox 2 | -0.3 |
| SLC4A11 | solute carrier family 4, sodium borate transporter, member 11 | -0.3 |
| SGMS2 | sphingomyelin synthase 2 | -0.3 |
| GNAZ | guanine nucleotide binding protein (G protein), alpha z polypeptide | -0.3 |
| ZNF431 | zinc finger protein 431 | -0.3 |
| WDR60 | WD repeat domain 60 | -0.29 |
| STK17B | serine/threonine kinase 17b | -0.29 |
| KCTD12 | potassium channel tetramerization domain containing 12 | -0.29 |
| PRMT2 | protein arginine methyltransferase 2 | -0.29 |
| LIN7A | lin-7 homolog A (C. elegans) | -0.28 |
| RNF13 | ring finger protein 13 | -0.28 |
| ZC3H14 | zinc finger CCCH-type containing 14 | -0.28 |
| HIST2H2AB | histone cluster 2, H2ab | -0.27 |
| TMEM39B | transmembrane protein 39B | -0.27 |
| DPYD | dihydropyrimidine dehydrogenase | -0.26 |
| MAD2L1BP | MAD2L1 binding protein | -0.26 |
| ETV5 | ets variant 5 | -0.26 |
| PABPN1 | poly(A) binding protein, nuclear 1 | -0.26 |
| CCSAP | centriole, cilia and spindle-associated protein | -0.26 |
| F13A1 | coagulation factor XIII, A1 polypeptide | -0.26 |
| CTSC | cathepsin C | -0.26 |
| ANKRD36 | ankyrin repeat domain 36 | -0.26 |
| RGS12 | regulator of G-protein signaling 12 | -0.26 |
| SKIL | SKI-like proto-oncogene | -0.26 |
| STK19 | serine/threonine kinase 19 | -0.26 |
| DNPH1 | 2'-deoxynucleoside 5'-phosphate N-hydrolase 1 | -0.26 |
| FOXO1 | forkhead box O1 | -0.25 |
| ANXA6 | annexin A6 | -0.25 |
| ALDH1A1 | aldehyde dehydrogenase 1 family, member A1 | -0.25 |
| TLE1 | transducin-like enhancer of split 1 (E(sp1) homolog, Drosophila) | -0.25 |
| ATP8B3 | ATPase, aminophospholipid transporter, class I, type 8B, member 3 | -0.25 |
| RWDD2A | RWD domain containing 2A | -0.25 |
| MAGEA2 | melanoma antigen family A2 | -0.24 |
| JPT1 | Jupiter microtubule associated homolog 1 | -0.24 |
| ASB13 | ankyrin repeat and SOCS box containing 13 | -0.24 |
| STC2 | stanniocalcin 2 | -0.24 |
| NUDT7 | nudix (nucleoside diphosphate linked moiety X)-type motif 7 | -0.24 |
| TTC17 | tetratricopeptide repeat domain 17 | -0.24 |
| ARHGAP31 | Rho GTPase activating protein 31 | -0.24 |
| CDKN1A | cyclin-dependent kinase inhibitor 1A (p21, Cip1) | -0.24 |
| CNTLN | centlein, centrosomal protein | -0.23 |
| INO80C | INO80 complex subunit C | -0.23 |
| ANAPC11 | anaphase promoting complex subunit 11 | -0.23 |
| TMEM161B | transmembrane protein 161B | -0.23 |
| ZNF711 | zinc finger protein 711 | -0.23 |
| FLNA | filamin A, alpha | -0.23 |
| CDA | cytidine deaminase | -0.23 |
| SULT1C2 | sulfotransferase family, cytosolic, 1C, member 2 | -0.22 |
| DENND5A | DENN/MADD domain containing 5A | -0.22 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | -0.22 |
| AGTPBP1 | ATP/GTP binding protein 1 | -0.22 |
| TPM1 | tropomyosin 1 (alpha) | -0.22 |
| EXT1 | exostosin glycosyltransferase 1 | -0.22 |
| PPHLN1 | periphilin 1 | -0.22 |
| METAP1D | methionyl aminopeptidase type 1D (mitochondrial) | -0.22 |
| ZNF639 | zinc finger protein 639 | -0.22 |
| PLAUR | plasminogen activator, urokinase receptor | -0.22 |
| GMEB2 | glucocorticoid modulatory element binding protein 2 | -0.22 |
| FAM210B | family with sequence similarity 210, member B | -0.22 |
