| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | (S)-Crizotinib perturbation in A-172 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the (S)-Crizotinib_A-172 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| SPARC | secreted protein, acidic, cysteine-rich (osteonectin) | 0.326353 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.137548 |
| ABCA1 | ATP-binding cassette, sub-family A (ABC1), member 1 | 0.124945 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0836267 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | 0.0780101 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0779861 |
| IGFBP3 | insulin-like growth factor binding protein 3 | 0.0771104 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.0699759 |
| MYOF | myoferlin | 0.0692438 |
| SLC39A11 | solute carrier family 39, member 11 | 0.056817 |
| DLG1 | discs, large homolog 1 (Drosophila) | 0.0532955 |
| LDHA | lactate dehydrogenase A | 0.0480326 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0479627 |
| PODXL | podocalyxin-like | 0.0478005 |
| DST | dystonin | 0.0467014 |
| ASPH | aspartate beta-hydroxylase | 0.0448547 |
| CACNA2D3 | calcium channel, voltage-dependent, alpha 2/delta subunit 3 | 0.0408127 |
| POTEF | POTE ankyrin domain family, member F | 0.0402035 |
| IFIT2 | interferon-induced protein with tetratricopeptide repeats 2 | 0.0400334 |
| CDH13 | cadherin 13 | 0.0394777 |
| HDAC9 | histone deacetylase 9 | 0.0382294 |
| DCLK2 | doublecortin-like kinase 2 | 0.0378211 |
| UAP1 | UDP-N-acetylglucosamine pyrophosphorylase 1 | 0.0373679 |
| FBN1 | fibrillin 1 | 0.0354718 |
| NFE2L1 | nuclear factor, erythroid 2-like 1 | 0.035219 |
| COL4A1 | collagen, type IV, alpha 1 | 0.035085 |
| COPA | coatomer protein complex, subunit alpha | 0.03498 |
| KLF7 | Kruppel-like factor 7 (ubiquitous) | 0.0349522 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | 0.0342844 |
| PRELID2 | PRELI domain containing 2 | 0.033775 |
| MSN | moesin | 0.0334954 |
| ANKRD11 | ankyrin repeat domain 11 | 0.0329167 |
| MBNL1 | muscleblind-like splicing regulator 1 | 0.0329152 |
| ADAM9 | ADAM metallopeptidase domain 9 | 0.0321514 |
| RTN4 | reticulon 4 | 0.031982 |
| LCOR | ligand dependent nuclear receptor corepressor | 0.0311811 |
| ITPRID2 | ITPR interacting domain containing 2 | 0.0286418 |
| C1D | C1D nuclear receptor corepressor | 0.0283207 |
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa | 0.0277832 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0273508 |
| VCL | vinculin | 0.0272391 |
| GPC6 | glypican 6 | 0.0266586 |
| FNIP1 | folliculin interacting protein 1 | 0.0259972 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0255954 |
| HUWE1 | HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase | 0.0251598 |
| TENM3 | teneurin transmembrane protein 3 | 0.0250497 |
| MBNL2 | muscleblind-like splicing regulator 2 | 0.024754 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0246157 |
| ADAM17 | ADAM metallopeptidase domain 17 | 0.02454 |
| NHS | Nance-Horan syndrome (congenital cataracts and dental anomalies) | 0.0244668 |
| ZNF148 | zinc finger protein 148 | 0.0243785 |
| B2M | beta-2-microglobulin | 0.0243372 |
| ZNF292 | zinc finger protein 292 | 0.0242605 |
| NOTCH2 | notch 2 | 0.0241223 |
| NBAS | neuroblastoma amplified sequence | 0.0241092 |
| VEGFA | vascular endothelial growth factor A | 0.0240247 |
| NEK7 | NIMA-related kinase 7 | 0.0240188 |
| IFIT3 | interferon-induced protein with tetratricopeptide repeats 3 | 0.023797 |
| PICALM | phosphatidylinositol binding clathrin assembly protein | 0.0234541 |
| FLNA | filamin A, alpha | 0.0231026 |
| XPO1 | exportin 1 | 0.0230734 |
| RSAD2 | radical S-adenosyl methionine domain containing 2 | 0.0228695 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0226538 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | 0.0222758 |
| SLC22A23 | solute carrier family 22, member 23 | 0.0221812 |
| INSIG2 | insulin induced gene 2 | 0.0218986 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0217896 |
| PHC3 | polyhomeotic homolog 3 (Drosophila) | 0.0217854 |
| SLC8A1 | solute carrier family 8 (sodium/calcium exchanger), member 1 | 0.0216385 |
| TOX | thymocyte selection-associated high mobility group box | 0.021501 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | 0.0214126 |
| EFNA5 | ephrin-A5 | 0.0213886 |
| MLLT10 | myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 10 | 0.0213585 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | 0.0211558 |
| CENPF | centromere protein F, 350/400kDa | 0.0211467 |
| CD109 | CD109 molecule | 0.0211321 |
| RHOBTB3 | Rho-related BTB domain containing 3 | 0.0210477 |
| SPDL1 | spindle apparatus coiled-coil protein 1 | 0.020815 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0207912 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | 0.0207067 |
| TFG | TRK-fused gene | 0.0206529 |
| CD44 | CD44 molecule (Indian blood group) | 0.0205921 |
| FADS2 | fatty acid desaturase 2 | 0.0205675 |
| LRRTM4 | leucine rich repeat transmembrane neuronal 4 | 0.0203249 |
| PPFIBP1 | PTPRF interacting protein, binding protein 1 (liprin beta 1) | 0.0202457 |
| GARS1 | glycyl-tRNA synthetase 1 | 0.0201885 |
| ARRDC3 | arrestin domain containing 3 | 0.0197597 |
| LRRC17 | leucine rich repeat containing 17 | 0.0196966 |
| MEF2A | myocyte enhancer factor 2A | 0.0196382 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | 0.0195483 |
| LHFPL6 | LHFPL tetraspan subfamily member 6 | 0.0186396 |
| DDX60 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 60 | 0.0185057 |
| ATP2C1 | ATPase, Ca++ transporting, type 2C, member 1 | 0.018482 |
| PDIA3 | protein disulfide isomerase family A, member 3 | 0.0178132 |
| DYRK1A | dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A | 0.0177944 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0177504 |
| ACSL3 | acyl-CoA synthetase long-chain family member 3 | 0.017588 |
| LHFPL2 | lipoma HMGIC fusion partner-like 2 | 0.0175867 |
| PKM | pyruvate kinase, muscle | 0.0175816 |
| NPC1 | Niemann-Pick disease, type C1 | 0.0175115 |
| Symbol | Name | Standardized Value |
|---|---|---|
| TMSB10 | thymosin beta 10 | -0.167328 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.120894 |
| VIM | vimentin | -0.103929 |
| MT2A | metallothionein 2A | -0.0791766 |
| LMNA | lamin A/C | -0.0789962 |
| PTMA | prothymosin, alpha | -0.0651338 |
| HLA-B | major histocompatibility complex, class I, B | -0.0566504 |
| ADAMTS6 | ADAM metallopeptidase with thrombospondin type 1 motif, 6 | -0.0489941 |
| TMSB4X | thymosin beta 4, X-linked | -0.0423092 |
| SLC25A37 | solute carrier family 25 (mitochondrial iron transporter), member 37 | -0.042256 |
| S100A6 | S100 calcium binding protein A6 | -0.0416036 |
| CAVIN1 | caveolae associated protein 1 | -0.0412434 |
| P4HA2 | prolyl 4-hydroxylase, alpha polypeptide II | -0.0393121 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.039282 |
| CALM1 | calmodulin 1 (phosphorylase kinase, delta) | -0.0375866 |
| COL3A1 | collagen, type III, alpha 1 | -0.0352176 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0342747 |
| ACTG1 | actin gamma 1 | -0.0340357 |
| MAP4 | microtubule-associated protein 4 | -0.0337911 |
| MDM2 | MDM2 proto-oncogene, E3 ubiquitin protein ligase | -0.0337433 |
| CCND1 | cyclin D1 | -0.0333985 |
| HLA-E | major histocompatibility complex, class I, E | -0.0329385 |
| LOXL2 | lysyl oxidase-like 2 | -0.0328332 |
| MARCKS | myristoylated alanine-rich protein kinase C substrate | -0.0327651 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.0316322 |
| DKK3 | dickkopf WNT signaling pathway inhibitor 3 | -0.0303924 |
| RPS8 | ribosomal protein S8 | -0.0290969 |
| COL1A2 | collagen, type I, alpha 2 | -0.0286085 |
| MX2 | MX dynamin-like GTPase 2 | -0.0280043 |
| HLA-C | major histocompatibility complex, class I, C | -0.0272946 |
| S100A10 | S100 calcium binding protein A10 | -0.0270337 |
| PLAT | plasminogen activator, tissue | -0.0270302 |
| S100A4 | S100 calcium binding protein A4 | -0.0268021 |
| UBC | ubiquitin C | -0.0267606 |
| FSTL1 | follistatin-like 1 | -0.0255232 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | -0.0250486 |
| RPS19 | ribosomal protein S19 | -0.0248809 |
| RPS24 | ribosomal protein S24 | -0.0244435 |
| CD99 | CD99 molecule | -0.0243964 |
| FBXL7 | F-box and leucine-rich repeat protein 7 | -0.024035 |
| RPS3 | ribosomal protein S3 | -0.0240022 |
| RPL35A | ribosomal protein L35a | -0.023886 |
| ARHGEF10 | Rho guanine nucleotide exchange factor (GEF) 10 | -0.0237714 |
| SERPINE2 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 | -0.023163 |
| RPL34 | ribosomal protein L34 | -0.0231556 |
| RPLP1 | ribosomal protein, large, P1 | -0.0229136 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | -0.0227676 |
| TBCA | tubulin folding cofactor A | -0.0227119 |
| GNAI2 | guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 2 | -0.0224591 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | -0.021086 |
| CANX | calnexin | -0.0207528 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | -0.0203726 |
| ALCAM | activated leukocyte cell adhesion molecule | -0.0202558 |
| STC1 | stanniocalcin 1 | -0.0200727 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | -0.0200721 |
| MT1X | metallothionein 1X | -0.0198623 |
| CDK13 | cyclin-dependent kinase 13 | -0.019724 |
| RPL37A | ribosomal protein L37a | -0.0196176 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | -0.0195842 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0195619 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | -0.0194869 |
| PLAUR | plasminogen activator, urokinase receptor | -0.0194159 |
| THBS2 | thrombospondin 2 | -0.0192579 |
| MYL12A | myosin, light chain 12A, regulatory, non-sarcomeric | -0.018754 |
| RIGI | RNA sensor RIG-I | -0.0187363 |
| ANKHD1 | ankyrin repeat and KH domain containing 1 | -0.0183904 |
| HSPB1 | heat shock 27kDa protein 1 | -0.0183202 |
| NUFIP2 | nuclear fragile X mental retardation protein interacting protein 2 | -0.0182194 |
| PPFIA1 | protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 1 | -0.0176225 |
| HDLBP | high density lipoprotein binding protein | -0.0174453 |
| KDM4B | lysine (K)-specific demethylase 4B | -0.0172888 |
| PCNP | PEST proteolytic signal containing nuclear protein | -0.0169345 |
| RPS6 | ribosomal protein S6 | -0.0168168 |
| GUK1 | guanylate kinase 1 | -0.0168055 |
| PARD3 | par-3 family cell polarity regulator | -0.0167921 |
| SLC38A1 | solute carrier family 38, member 1 | -0.0165831 |
| RBMS1 | RNA binding motif, single stranded interacting protein 1 | -0.0165633 |
| SRRM2 | serine/arginine repetitive matrix 2 | -0.0164465 |
| FSTL3 | follistatin-like 3 (secreted glycoprotein) | -0.0163714 |
| VDAC1 | voltage-dependent anion channel 1 | -0.0162007 |
| EHBP1 | EH domain binding protein 1 | -0.0161476 |
| TPM4 | tropomyosin 4 | -0.0159531 |
| LOX | lysyl oxidase | -0.0159246 |
| ANKRD10 | ankyrin repeat domain 10 | -0.0158655 |
| FTL | ferritin, light polypeptide | -0.015623 |
| RPL12 | ribosomal protein L12 | -0.0154638 |
| RAB1A | RAB1A, member RAS oncogene family | -0.0153934 |
| FAM114A1 | family with sequence similarity 114, member A1 | -0.0152728 |
| RPS13 | ribosomal protein S13 | -0.0152653 |
| PXDN | peroxidasin | -0.0150549 |
| RPL28 | ribosomal protein L28 | -0.0150296 |
| PRSS23 | protease, serine, 23 | -0.0149981 |
| GNAS | GNAS complex locus | -0.0148626 |
| BSG | basigin (Ok blood group) | -0.0148273 |
| SPAG9 | sperm associated antigen 9 | -0.014748 |
| CDPF1 | cysteine-rich, DPF motif domain containing 1 | -0.014644 |
| THY1 | Thy-1 cell surface antigen | -0.0146352 |
| RPS27A | ribosomal protein S27a | -0.0145383 |
| GDF15 | growth differentiation factor 15 | -0.0144065 |
| RPL31 | ribosomal protein L31 | -0.0143297 |
