| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | (S)-Crizotinib perturbation in CHP-212 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the (S)-Crizotinib_CHP-212 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.14367 |
| MEF2A | myocyte enhancer factor 2A | 0.125652 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.124561 |
| FAM13A | family with sequence similarity 13, member A | 0.0885558 |
| PTPRD | protein tyrosine phosphatase, receptor type, D | 0.0846758 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0808933 |
| LIMCH1 | LIM and calponin homology domains 1 | 0.0633676 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | 0.0605122 |
| DTNA | dystrobrevin, alpha | 0.0525516 |
| GULP1 | GULP, engulfment adaptor PTB domain containing 1 | 0.0508465 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0506801 |
| PCBP2 | poly(rC) binding protein 2 | 0.0495761 |
| REV3L | REV3-like, polymerase (DNA directed), zeta, catalytic subunit | 0.0492225 |
| ZNF292 | zinc finger protein 292 | 0.0488724 |
| SLITRK6 | SLIT and NTRK-like family, member 6 | 0.0486099 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0465345 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | 0.0462069 |
| VEGFA | vascular endothelial growth factor A | 0.0457943 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | 0.0457873 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0453606 |
| ACSL3 | acyl-CoA synthetase long-chain family member 3 | 0.0451811 |
| PTPRM | protein tyrosine phosphatase, receptor type, M | 0.0439186 |
| ASCC3 | activating signal cointegrator 1 complex subunit 3 | 0.0436421 |
| SCN9A | sodium channel, voltage gated, type IX alpha subunit | 0.0435489 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | 0.0414595 |
| ITPRID2 | ITPR interacting domain containing 2 | 0.0406778 |
| ZNF148 | zinc finger protein 148 | 0.0405865 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0402563 |
| ASPH | aspartate beta-hydroxylase | 0.039923 |
| PCDH9 | protocadherin 9 | 0.0396759 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0382666 |
| BCAT1 | branched chain amino-acid transaminase 1, cytosolic | 0.038229 |
| MSI2 | musashi RNA-binding protein 2 | 0.0378676 |
| PGK1 | phosphoglycerate kinase 1 | 0.0369005 |
| THSD4 | thrombospondin, type I, domain containing 4 | 0.0345285 |
| AHR | aryl hydrocarbon receptor | 0.033706 |
| SOS1 | son of sevenless homolog 1 (Drosophila) | 0.0330916 |
| XRN1 | 5'-3' exoribonuclease 1 | 0.032904 |
| ATXN1 | ataxin 1 | 0.0325728 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.0323786 |
| RNF145 | ring finger protein 145 | 0.0322365 |
| CENPF | centromere protein F, 350/400kDa | 0.0313063 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | 0.0310783 |
| NBEA | neurobeachin | 0.0308058 |
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa | 0.0307868 |
| NRG1 | neuregulin 1 | 0.0301225 |
| NDRG1 | N-myc downstream regulated 1 | 0.0300236 |
| DPH6 | diphthamine biosynthesis 6 | 0.029962 |
| SLC2A3 | solute carrier family 2 (facilitated glucose transporter), member 3 | 0.0296064 |
| CDH13 | cadherin 13 | 0.0293554 |
| FLNB | filamin B, beta | 0.0291419 |
| PKM | pyruvate kinase, muscle | 0.0290779 |
| ADGRB3 | adhesion G protein-coupled receptor B3 | 0.0289358 |
| ZNF638 | zinc finger protein 638 | 0.0286408 |
| PAPOLA | poly(A) polymerase alpha | 0.0284949 |
| HELZ | helicase with zinc finger | 0.028376 |
| RAD51B | RAD51 paralog B | 0.0283442 |
| TOP1 | topoisomerase (DNA) I | 0.0280174 |
| VCAN | versican | 0.0279942 |
| DIAPH2 | diaphanous-related formin 2 | 0.0276076 |
| LSAMP | limbic system-associated membrane protein | 0.0275705 |
| SFTPA2 | surfactant protein A2 | 0.0273742 |
| LDHA | lactate dehydrogenase A | 0.0272924 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0271992 |
| CAMK1D | calcium/calmodulin-dependent protein kinase ID | 0.0270468 |
| TTC3 | tetratricopeptide repeat domain 3 | 0.0267906 |
| LINGO2 | leucine rich repeat and Ig domain containing 2 | 0.0267875 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | 0.0265703 |
| PIAS2 | protein inhibitor of activated STAT, 2 | 0.0261885 |
| ATM | ATM serine/threonine kinase | 0.0260907 |
| COPA | coatomer protein complex, subunit alpha | 0.0259956 |
| INSIG2 | insulin induced gene 2 | 0.0258743 |
| CADM1 | cell adhesion molecule 1 | 0.0258458 |
| SMYD3 | SET and MYND domain containing 3 | 0.0258141 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | 0.0257898 |
| PEAK1 | pseudopodium-enriched atypical kinase 1 | 0.0257545 |
| DST | dystonin | 0.0256314 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | 0.0255552 |
| PICALM | phosphatidylinositol binding clathrin assembly protein | 0.0255327 |
| ST6GALNAC3 | ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 3 | 0.0255046 |
| ESYT2 | extended synaptotagmin-like protein 2 | 0.0254101 |
| IGFBP3 | insulin-like growth factor binding protein 3 | 0.0253759 |
| FXR1 | fragile X mental retardation, autosomal homolog 1 | 0.0252527 |
| MYCBP2 | MYC binding protein 2, E3 ubiquitin protein ligase | 0.0251977 |
| ENO1 | enolase 1, (alpha) | 0.0249193 |
| PLAT | plasminogen activator, tissue | 0.0246429 |
| TANC2 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 | 0.024547 |
| B2M | beta-2-microglobulin | 0.0243978 |
| PLEKHA2 | pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 2 | 0.0243812 |
| EZR | ezrin | 0.0243588 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | 0.0243569 |
| H1-3 | H1.3 linker histone, cluster member | 0.024195 |
| KDM6A | lysine (K)-specific demethylase 6A | 0.0241768 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | 0.0241477 |
| ZBTB20 | zinc finger and BTB domain containing 20 | 0.0239985 |
| SMAD3 | SMAD family member 3 | 0.0239131 |
| EXOC4 | exocyst complex component 4 | 0.0238729 |
| EGLN1 | egl-9 family hypoxia-inducible factor 1 | 0.0237652 |
| MAML2 | mastermind-like 2 (Drosophila) | 0.0236909 |
| TBL1XR1 | transducin (beta)-like 1 X-linked receptor 1 | 0.0236833 |
| Symbol | Name | Standardized Value |
|---|---|---|
| IGF2 | insulin-like growth factor 2 | -0.17235 |
| COL1A1 | collagen, type I, alpha 1 | -0.10805 |
| PTMA | prothymosin, alpha | -0.105619 |
| DDX1 | DEAD (Asp-Glu-Ala-Asp) box helicase 1 | -0.101216 |
| FMN1 | formin 1 | -0.0886332 |
| ACTG1 | actin gamma 1 | -0.0874383 |
| TPST1 | tyrosylprotein sulfotransferase 1 | -0.0862182 |
| LGR5 | leucine-rich repeat containing G protein-coupled receptor 5 | -0.0767089 |
| COL3A1 | collagen, type III, alpha 1 | -0.0571355 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0542443 |
| RPL38 | ribosomal protein L38 | -0.0539729 |
| DDX5 | DEAD (Asp-Glu-Ala-Asp) box helicase 5 | -0.0484676 |
| EXT1 | exostosin glycosyltransferase 1 | -0.0476709 |
| RIGI | RNA sensor RIG-I | -0.0456841 |
| RPLP1 | ribosomal protein, large, P1 | -0.041809 |
| VCL | vinculin | -0.0416243 |
| RPL19 | ribosomal protein L19 | -0.041346 |
| CANX | calnexin | -0.039133 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | -0.0385912 |
| GLCCI1 | glucocorticoid induced 1 | -0.0384514 |
| ARID5B | AT rich interactive domain 5B (MRF1-like) | -0.0384375 |
| LPIN1 | lipin 1 | -0.0380422 |
| RPS6 | ribosomal protein S6 | -0.0372181 |
| FRMD4A | FERM domain containing 4A | -0.0370663 |
| SIK2 | salt-inducible kinase 2 | -0.03687 |
| HAND2 | heart and neural crest derivatives expressed 2 | -0.0356464 |
| RPS24 | ribosomal protein S24 | -0.0351085 |
| HMGB2 | high mobility group box 2 | -0.0333025 |
| UNC5C | unc-5 homolog C (C. elegans) | -0.0323499 |
| AOPEP | aminopeptidase O (putative) | -0.0319297 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0318146 |
| RPL34 | ribosomal protein L34 | -0.0309815 |
| TANC1 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 1 | -0.0305514 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.0304973 |
| NCOA7 | nuclear receptor coactivator 7 | -0.0296845 |
| RNF213 | ring finger protein 213 | -0.0291159 |
| TRIB2 | tribbles pseudokinase 2 | -0.0290365 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0278966 |
| RPL32 | ribosomal protein L32 | -0.0278847 |
| NME2 | NME/NM23 nucleoside diphosphate kinase 2 | -0.0278547 |
| NT5C2 | 5'-nucleotidase, cytosolic II | -0.0271218 |
| RPL35A | ribosomal protein L35a | -0.0258952 |
| IGFBP4 | insulin-like growth factor binding protein 4 | -0.0254712 |
| FBXO34 | F-box protein 34 | -0.0253042 |
| PPM1D | protein phosphatase, Mg2+/Mn2+ dependent, 1D | -0.0248537 |
| CDC27 | cell division cycle 27 | -0.0243101 |
| RPL26 | ribosomal protein L26 | -0.0240824 |
| RBM39 | RNA binding motif protein 39 | -0.023956 |
| RPL28 | ribosomal protein L28 | -0.0236835 |
| NFE2L2 | nuclear factor, erythroid 2-like 2 | -0.0235014 |
| APPBP2 | amyloid beta precursor protein (cytoplasmic tail) binding protein 2 | -0.0234898 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | -0.023312 |
| IER3 | immediate early response 3 | -0.0233112 |
| ZNF804A | zinc finger protein 804A | -0.0230207 |
| TTC17 | tetratricopeptide repeat domain 17 | -0.0230092 |
| KIF21A | kinesin family member 21A | -0.0227353 |
| PDZRN3 | PDZ domain containing ring finger 3 | -0.022706 |
| ADARB1 | adenosine deaminase, RNA-specific, B1 | -0.0224724 |
| DDX17 | DEAD (Asp-Glu-Ala-Asp) box helicase 17 | -0.0224511 |
| CFDP1 | craniofacial development protein 1 | -0.0222967 |
| NPLOC4 | nuclear protein localization 4 homolog (S. cerevisiae) | -0.0221995 |
| SCLT1 | sodium channel and clathrin linker 1 | -0.0216939 |
| PDE10A | phosphodiesterase 10A | -0.0216805 |
| GRK5 | G protein-coupled receptor kinase 5 | -0.0214573 |
| PLPP1 | phospholipid phosphatase 1 | -0.0213757 |
| BMERB1 | bMERB domain containing 1 | -0.0211387 |
| CCND1 | cyclin D1 | -0.0211254 |
| SOD2 | superoxide dismutase 2, mitochondrial | -0.0210123 |
| GNAS | GNAS complex locus | -0.0208766 |
| FBXL20 | F-box and leucine-rich repeat protein 20 | -0.0206638 |
| EIF3A | eukaryotic translation initiation factor 3, subunit A | -0.0206261 |
| TBX2 | T-box 2 | -0.0204758 |
| PRKAR1A | protein kinase, cAMP-dependent, regulatory, type I, alpha | -0.0203354 |
| PNRC1 | proline-rich nuclear receptor coactivator 1 | -0.0202612 |
| FNDC3A | fibronectin type III domain containing 3A | -0.0202365 |
| THBS1 | thrombospondin 1 | -0.0201939 |
| AKT3 | v-akt murine thymoma viral oncogene homolog 3 | -0.0200076 |
| LMNA | lamin A/C | -0.0200048 |
| GPATCH8 | G patch domain containing 8 | -0.0199135 |
| ADAMTS9 | ADAM metallopeptidase with thrombospondin type 1 motif, 9 | -0.0197808 |
| RAB21 | RAB21, member RAS oncogene family | -0.0196574 |
| SMCHD1 | structural maintenance of chromosomes flexible hinge domain containing 1 | -0.0196189 |
| RPS27 | ribosomal protein S27 | -0.0195629 |
| PRRC2C | proline-rich coiled-coil 2C | -0.0195353 |
| EDEM3 | ER degradation enhancer, mannosidase alpha-like 3 | -0.0195057 |
| CLTC | clathrin, heavy chain (Hc) | -0.0194803 |
| PRSS12 | protease, serine, 12 (neurotrypsin, motopsin) | -0.0194281 |
| SYNPO2 | synaptopodin 2 | -0.0194187 |
| UBE2O | ubiquitin-conjugating enzyme E2O | -0.0192914 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | -0.0191185 |
| ZNF609 | zinc finger protein 609 | -0.0190948 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | -0.0189329 |
| PMP22 | peripheral myelin protein 22 | -0.0189126 |
| NUFIP2 | nuclear fragile X mental retardation protein interacting protein 2 | -0.018894 |
| PELO | pelota homolog (Drosophila) | -0.0188392 |
| ARF1 | ADP-ribosylation factor 1 | -0.0187795 |
| PLCB1 | phospholipase C, beta 1 (phosphoinositide-specific) | -0.0186964 |
| SMARCE1 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily e, member 1 | -0.0183926 |
| MDM2 | MDM2 proto-oncogene, E3 ubiquitin protein ligase | -0.0181321 |
| RPL6 | ribosomal protein L6 | -0.018093 |
