| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | (S)-Crizotinib perturbation in Hs 766T cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the (S)-Crizotinib_Hs 766T drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| MSN | moesin | 0.0608051 |
| SQLE | squalene epoxidase | 0.0423104 |
| KDM6A | lysine (K)-specific demethylase 6A | 0.0402369 |
| PALM2AKAP2 | PALM2 and AKAP2 fusion | 0.0387756 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | 0.0382662 |
| SMAD3 | SMAD family member 3 | 0.0362645 |
| CDKN2A | cyclin-dependent kinase inhibitor 2A | 0.0361403 |
| POTEF | POTE ankyrin domain family, member F | 0.0302593 |
| HMGCS1 | 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble) | 0.0298181 |
| ACSS2 | acyl-CoA synthetase short-chain family member 2 | 0.0290016 |
| NAV2 | neuron navigator 2 | 0.0270181 |
| PICALM | phosphatidylinositol binding clathrin assembly protein | 0.0261716 |
| ACSL3 | acyl-CoA synthetase long-chain family member 3 | 0.025893 |
| LAMA5 | laminin, alpha 5 | 0.0240975 |
| PCDH1 | protocadherin 1 | 0.0237382 |
| EPHA2 | EPH receptor A2 | 0.0229506 |
| LAMC1 | laminin, gamma 1 (formerly LAMB2) | 0.0217919 |
| GRB10 | growth factor receptor-bound protein 10 | 0.0217429 |
| CYP51A1 | cytochrome P450, family 51, subfamily A, polypeptide 1 | 0.0209321 |
| MTSS1 | metastasis suppressor 1 | 0.0204081 |
| LDLR | low density lipoprotein receptor | 0.0201648 |
| PLS3 | plastin 3 | 0.0196959 |
| FAR1 | fatty acyl CoA reductase 1 | 0.0194624 |
| SLCO4A1 | solute carrier organic anion transporter family, member 4A1 | 0.0193797 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.0184745 |
| SREBF2 | sterol regulatory element binding transcription factor 2 | 0.0175788 |
| MSMO1 | methylsterol monooxygenase 1 | 0.017503 |
| PCBP2 | poly(rC) binding protein 2 | 0.0175009 |
| ABTB2 | ankyrin repeat and BTB (POZ) domain containing 2 | 0.0174161 |
| SOX13 | SRY (sex determining region Y)-box 13 | 0.0167038 |
| PDLIM5 | PDZ and LIM domain 5 | 0.0166691 |
| RNF145 | ring finger protein 145 | 0.0165701 |
| PODXL | podocalyxin-like | 0.0161667 |
| MCL1 | myeloid cell leukemia 1 | 0.0158801 |
| HDGF | hepatoma-derived growth factor | 0.0157716 |
| DNAJB6 | DnaJ (Hsp40) homolog, subfamily B, member 6 | 0.0156715 |
| FOXO1 | forkhead box O1 | 0.0155528 |
| MUC5AC | mucin 5AC, oligomeric mucus/gel-forming | 0.0154137 |
| CDH11 | cadherin 11, type 2, OB-cadherin (osteoblast) | 0.0152422 |
| SLK | STE20-like kinase | 0.015213 |
| LUC7L3 | LUC7-like 3 (S. cerevisiae) | 0.0149587 |
| EMD | emerin | 0.0149157 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | 0.0148204 |
| FOSL1 | FOS-like antigen 1 | 0.0147606 |
| GIGYF2 | GRB10 interacting GYF protein 2 | 0.0146017 |
| SPIRE1 | spire-type actin nucleation factor 1 | 0.0140103 |
| HSD17B12 | hydroxysteroid (17-beta) dehydrogenase 12 | 0.0139296 |
| TINAGL1 | tubulointerstitial nephritis antigen-like 1 | 0.0137367 |
| ARHGEF28 | Rho guanine nucleotide exchange factor (GEF) 28 | 0.0136606 |
| ARHGAP21 | Rho GTPase activating protein 21 | 0.0134288 |
| GPRC5B | G protein-coupled receptor, class C, group 5, member B | 0.0133204 |
| PFKFB2 | 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 2 | 0.0132945 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0131856 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0131372 |
| HIVEP1 | human immunodeficiency virus type I enhancer binding protein 1 | 0.0129288 |
| VEGFA | vascular endothelial growth factor A | 0.0128866 |
| FLNA | filamin A, alpha | 0.0128589 |
| ANKH | ANKH inorganic pyrophosphate transport regulator | 0.0127491 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0127263 |
| HNRNPR | heterogeneous nuclear ribonucleoprotein R | 0.0127063 |
| SQSTM1 | sequestosome 1 | 0.012607 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0125966 |
| OGT | O-linked N-acetylglucosamine (GlcNAc) transferase | 0.0125782 |
| HNRNPM | heterogeneous nuclear ribonucleoprotein M | 0.0125388 |
| NPC1 | Niemann-Pick disease, type C1 | 0.0125324 |
| INSIG1 | insulin induced gene 1 | 0.0125101 |
| USP12 | ubiquitin specific peptidase 12 | 0.012455 |
| LUZP1 | leucine zipper protein 1 | 0.0124273 |
| ATP13A3 | ATPase type 13A3 | 0.0124176 |
| NRIP1 | nuclear receptor interacting protein 1 | 0.012284 |
| BCL9L | B-cell CLL/lymphoma 9-like | 0.0122499 |
| ITCH | itchy E3 ubiquitin protein ligase | 0.0120396 |
| ITPR3 | inositol 1,4,5-trisphosphate receptor, type 3 | 0.0119807 |
| CPEB2 | cytoplasmic polyadenylation element binding protein 2 | 0.0119487 |
| USP9X | ubiquitin specific peptidase 9, X-linked | 0.0118731 |
| ZMIZ2 | zinc finger, MIZ-type containing 2 | 0.0118399 |
| CCNT2 | cyclin T2 | 0.011721 |
| FDPS | farnesyl diphosphate synthase | 0.0116633 |
| VEGFC | vascular endothelial growth factor C | 0.0115107 |
| SND1 | staphylococcal nuclease and tudor domain containing 1 | 0.0114504 |
| RCOR1 | REST corepressor 1 | 0.011424 |
| EGR1 | early growth response 1 | 0.0113583 |
| CAPRIN2 | caprin family member 2 | 0.0112839 |
| LRRFIP2 | leucine rich repeat (in FLII) interacting protein 2 | 0.011234 |
| RBM26 | RNA binding motif protein 26 | 0.0111352 |
| BPNT2 | 3'(2'), 5'-bisphosphate nucleotidase 2 | 0.0110999 |
| SFPQ | splicing factor proline/glutamine-rich | 0.0110807 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0110368 |
| MNT | MAX network transcriptional repressor | 0.0110079 |
| RAB8B | RAB8B, member RAS oncogene family | 0.010951 |
| ACACA | acetyl-CoA carboxylase alpha | 0.0108624 |
| YAP1 | Yes-associated protein 1 | 0.0108457 |
| IWS1 | IWS1 homolog (S. cerevisiae) | 0.0107945 |
| RNASE1 | ribonuclease, RNase A family, 1 (pancreatic) | 0.0107683 |
| DHRS3 | dehydrogenase/reductase (SDR family) member 3 | 0.0107425 |
| TMC7 | transmembrane channel-like 7 | 0.0106914 |
| C1D | C1D nuclear receptor corepressor | 0.0106818 |
| BCAR3 | breast cancer anti-estrogen resistance 3 | 0.0106706 |
| AMBRA1 | autophagy/beclin-1 regulator 1 | 0.0106452 |
| SRSF3 | serine/arginine-rich splicing factor 3 | 0.0106116 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.206344 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.126852 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.125101 |
| NDRG1 | N-myc downstream regulated 1 | -0.122033 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.121436 |
| TIMP3 | TIMP metallopeptidase inhibitor 3 | -0.121061 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.116379 |
| PTMA | prothymosin, alpha | -0.109197 |
| EMP1 | epithelial membrane protein 1 | -0.107486 |
| S100A10 | S100 calcium binding protein A10 | -0.101629 |
| H1-0 | H1.0 linker histone | -0.0987985 |
| AHNAK | AHNAK nucleoprotein | -0.0977402 |
| TMSB4X | thymosin beta 4, X-linked | -0.0958152 |
| STC1 | stanniocalcin 1 | -0.0926591 |
| ERC2 | ELKS/RAB6-interacting/CAST family member 2 | -0.0892173 |
| CANX | calnexin | -0.0852713 |
| ANXA1 | annexin A1 | -0.0814921 |
| RPS21 | ribosomal protein S21 | -0.0734572 |
| CD44 | CD44 molecule (Indian blood group) | -0.0685275 |
| TMSB10 | thymosin beta 10 | -0.0677641 |
| DPYD | dihydropyrimidine dehydrogenase | -0.0654448 |
| ATP1B1 | ATPase, Na+/K+ transporting, beta 1 polypeptide | -0.0645285 |
| YWHAB | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta | -0.0624059 |
| CAV1 | caveolin 1, caveolae protein, 22kDa | -0.0610712 |
| MT2A | metallothionein 2A | -0.0602398 |
| CLU | clusterin | -0.0597061 |
| PGK1 | phosphoglycerate kinase 1 | -0.0594668 |
| HLA-B | major histocompatibility complex, class I, B | -0.0583855 |
| RPS8 | ribosomal protein S8 | -0.0561684 |
| LDHA | lactate dehydrogenase A | -0.0543487 |
| KRT17 | keratin 17, type I | -0.0541457 |
| IRF2BP2 | interferon regulatory factor 2 binding protein 2 | -0.053723 |
| MARCKS | myristoylated alanine-rich protein kinase C substrate | -0.0536489 |
| ENO1 | enolase 1, (alpha) | -0.053373 |
| YBX3 | Y box binding protein 3 | -0.0524548 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.0510778 |
| RPS24 | ribosomal protein S24 | -0.0510622 |
| VDAC1 | voltage-dependent anion channel 1 | -0.0504929 |
| RPLP1 | ribosomal protein, large, P1 | -0.0493902 |
| ANLN | anillin, actin binding protein | -0.0485888 |
| FOXP1 | forkhead box P1 | -0.0480272 |
| ITGA6 | integrin, alpha 6 | -0.0475144 |
| IFITM3 | interferon induced transmembrane protein 3 | -0.0473129 |
| STAU1 | staufen double-stranded RNA binding protein 1 | -0.0468338 |
| ANXA2 | annexin A2 | -0.0462016 |
| LMNA | lamin A/C | -0.0456826 |
| EZR | ezrin | -0.0455509 |
| RBM39 | RNA binding motif protein 39 | -0.0453164 |
| GNAS | GNAS complex locus | -0.0440453 |
| MT1X | metallothionein 1X | -0.0440354 |
| MORF4L2 | mortality factor 4 like 2 | -0.0426359 |
| SAMD9 | sterile alpha motif domain containing 9 | -0.0425119 |
| DUSP6 | dual specificity phosphatase 6 | -0.0420264 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0416548 |
| MYOF | myoferlin | -0.0414384 |
| KDM3A | lysine (K)-specific demethylase 3A | -0.0410339 |
| PHLDB2 | pleckstrin homology-like domain, family B, member 2 | -0.0410064 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.0402601 |
| RPLP0 | ribosomal protein, large, P0 | -0.0397567 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | -0.0395155 |
| JMJD1C | jumonji domain containing 1C | -0.0387691 |
| RPL8 | ribosomal protein L8 | -0.0385939 |
| IFI16 | interferon, gamma-inducible protein 16 | -0.0378298 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | -0.0377516 |
| ARF1 | ADP-ribosylation factor 1 | -0.0374408 |
| HIVEP3 | human immunodeficiency virus type I enhancer binding protein 3 | -0.0371569 |
| RPS25 | ribosomal protein S25 | -0.0369616 |
| GOLGB1 | golgin B1 | -0.0369548 |
| NPEPPS | aminopeptidase puromycin sensitive | -0.0368709 |
| CEMIP | cell migration inducing protein, hyaluronan binding | -0.0367081 |
| RPL11 | ribosomal protein L11 | -0.0365278 |
| S100A6 | S100 calcium binding protein A6 | -0.0364428 |
| UBC | ubiquitin C | -0.0364095 |
| SEC31A | SEC31 homolog A (S. cerevisiae) | -0.0358655 |
| CUL4B | cullin 4B | -0.0356205 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | -0.0355607 |
| MBNL2 | muscleblind-like splicing regulator 2 | -0.0354624 |
| FTL | ferritin, light polypeptide | -0.0348568 |
| TXNIP | thioredoxin interacting protein | -0.0347703 |
| RRBP1 | ribosome binding protein 1 | -0.034556 |
| PTPN13 | protein tyrosine phosphatase, non-receptor type 13 (APO-1/CD95 (Fas)-associated phosphatase) | -0.034389 |
| CAVIN1 | caveolae associated protein 1 | -0.0342074 |
| CD99 | CD99 molecule | -0.0341576 |
| RPS6 | ribosomal protein S6 | -0.0340713 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0331085 |
| HDLBP | high density lipoprotein binding protein | -0.0329289 |
| RPLP2 | ribosomal protein, large, P2 | -0.0328685 |
| CALR | calreticulin | -0.0328034 |
| FNDC3A | fibronectin type III domain containing 3A | -0.032529 |
| ARFGEF2 | ADP-ribosylation factor guanine nucleotide-exchange factor 2 (brefeldin A-inhibited) | -0.0323604 |
| IER3 | immediate early response 3 | -0.0320365 |
| UBE2V1 | ubiquitin-conjugating enzyme E2 variant 1 | -0.0319686 |
| ARPC2 | actin related protein 2/3 complex, subunit 2, 34kDa | -0.0318248 |
| RPS13 | ribosomal protein S13 | -0.0313747 |
| NF1 | neurofibromin 1 | -0.0312289 |
| SH3BGRL3 | SH3 domain binding glutamate-rich protein like 3 | -0.0308821 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | -0.0307306 |
| EIF4G3 | eukaryotic translation initiation factor 4 gamma, 3 | -0.0307174 |
| YBX1 | Y box binding protein 1 | -0.0305791 |
| AP3B1 | adaptor-related protein complex 3, beta 1 subunit | -0.0304422 |
