| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | (S)-Crizotinib perturbation in SNU-1 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the (S)-Crizotinib_SNU-1 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | 0.222591 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | 0.208901 |
| SSBP2 | single-stranded DNA binding protein 2 | 0.101024 |
| ZNF292 | zinc finger protein 292 | 0.0712266 |
| ELOVL5 | ELOVL fatty acid elongase 5 | 0.0691031 |
| PDE4B | phosphodiesterase 4B, cAMP-specific | 0.0683169 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0636994 |
| GOLGA4 | golgin A4 | 0.059862 |
| CDC73 | cell division cycle 73 | 0.055235 |
| QKI | QKI, KH domain containing, RNA binding | 0.0541375 |
| WDR43 | WD repeat domain 43 | 0.0536902 |
| PDGFC | platelet derived growth factor C | 0.0536546 |
| GARS1 | glycyl-tRNA synthetase 1 | 0.0508066 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | 0.0481693 |
| COG6 | component of oligomeric golgi complex 6 | 0.0441577 |
| TFG | TRK-fused gene | 0.0431064 |
| INPP4B | inositol polyphosphate-4-phosphatase, type II, 105kDa | 0.0428224 |
| COPA | coatomer protein complex, subunit alpha | 0.042313 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | 0.0404 |
| CYP51A1 | cytochrome P450, family 51, subfamily A, polypeptide 1 | 0.0400542 |
| PRRC1 | proline-rich coiled-coil 1 | 0.0399953 |
| NUP58 | nucleoporin 58 | 0.0399356 |
| CNOT6L | CCR4-NOT transcription complex, subunit 6-like | 0.0398362 |
| SEC31A | SEC31 homolog A (S. cerevisiae) | 0.0377508 |
| TJP1 | tight junction protein 1 | 0.037371 |
| HELZ | helicase with zinc finger | 0.0366357 |
| SOX6 | SRY (sex determining region Y)-box 6 | 0.036505 |
| SYNCRIP | synaptotagmin binding, cytoplasmic RNA interacting protein | 0.0361418 |
| ZEB1 | zinc finger E-box binding homeobox 1 | 0.0359048 |
| ANKRD11 | ankyrin repeat domain 11 | 0.0355916 |
| ANK2 | ankyrin 2, neuronal | 0.0344626 |
| MSMO1 | methylsterol monooxygenase 1 | 0.0336808 |
| KDM6A | lysine (K)-specific demethylase 6A | 0.033361 |
| MATR3 | matrin 3 | 0.0330805 |
| PCBP2 | poly(rC) binding protein 2 | 0.0329155 |
| CRY1 | cryptochrome circadian clock 1 | 0.0321769 |
| LDHA | lactate dehydrogenase A | 0.0319622 |
| MLLT10 | myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 10 | 0.0318605 |
| TMEM41B | transmembrane protein 41B | 0.0315452 |
| TMEM39A | transmembrane protein 39A | 0.0311147 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0309471 |
| NFIA | nuclear factor I/A | 0.0309017 |
| BCLAF1 | BCL2-associated transcription factor 1 | 0.030824 |
| NEBL | nebulette | 0.0307771 |
| RPLP0 | ribosomal protein, large, P0 | 0.0304305 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | 0.0298956 |
| RHBDD1 | rhomboid domain containing 1 | 0.029675 |
| PUM2 | pumilio RNA-binding family member 2 | 0.0288627 |
| COG5 | component of oligomeric golgi complex 5 | 0.0287515 |
| SCFD2 | sec1 family domain containing 2 | 0.0286715 |
| BRWD1 | bromodomain and WD repeat domain containing 1 | 0.0283724 |
| ZFAND3 | zinc finger, AN1-type domain 3 | 0.0283293 |
| DHX15 | DEAH (Asp-Glu-Ala-His) box helicase 15 | 0.0282317 |
| MON2 | MON2 homolog (S. cerevisiae) | 0.0281958 |
| UBE2D3 | ubiquitin-conjugating enzyme E2D 3 | 0.0279791 |
| B3GALT1 | UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 1 | 0.0279577 |
| EIF2AK3 | eukaryotic translation initiation factor 2-alpha kinase 3 | 0.0277531 |
| PDE10A | phosphodiesterase 10A | 0.0275237 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | 0.0273822 |
| GOLGA2 | golgin A2 | 0.0272624 |
| RPL23 | ribosomal protein L23 | 0.0272339 |
| KDM3A | lysine (K)-specific demethylase 3A | 0.0269186 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0267047 |
| MORF4L1 | mortality factor 4 like 1 | 0.0265435 |
| HNRNPR | heterogeneous nuclear ribonucleoprotein R | 0.026123 |
| EPS8 | epidermal growth factor receptor pathway substrate 8 | 0.0259297 |
| SREK1 | splicing regulatory glutamine/lysine-rich protein 1 | 0.0256821 |
| VGLL4 | vestigial-like family member 4 | 0.0254406 |
| CLINT1 | clathrin interactor 1 | 0.0252957 |
| RBM25 | RNA binding motif protein 25 | 0.0252677 |
| TNPO1 | transportin 1 | 0.0252633 |
| RAB6A | RAB6A, member RAS oncogene family | 0.0251673 |
| CACNB4 | calcium channel, voltage-dependent, beta 4 subunit | 0.0251095 |
| DHX9 | DEAH (Asp-Glu-Ala-His) box helicase 9 | 0.025049 |
| ECT2 | epithelial cell transforming 2 | 0.024881 |
| ACACA | acetyl-CoA carboxylase alpha | 0.0247397 |
| SEC23A | Sec23 homolog A (S. cerevisiae) | 0.0246368 |
| PPP2R2A | protein phosphatase 2, regulatory subunit B, alpha | 0.0246042 |
| SREBF2 | sterol regulatory element binding transcription factor 2 | 0.0243035 |
| SUCO | SUN domain containing ossification factor | 0.024258 |
| MARCHF6 | membrane associated ring-CH-type finger 6 | 0.0242293 |
| DPM1 | dolichyl-phosphate mannosyltransferase polypeptide 1, catalytic subunit | 0.0242006 |
| EVI5 | ecotropic viral integration site 5 | 0.023864 |
| PAICS | phosphoribosylaminoimidazole carboxylase, phosphoribosylaminoimidazole succinocarboxamide synthetase | 0.0235227 |
| RBMS3 | RNA binding motif, single stranded interacting protein 3 | 0.0234311 |
| DLG1 | discs, large homolog 1 (Drosophila) | 0.0234308 |
| GNL3 | guanine nucleotide binding protein-like 3 (nucleolar) | 0.0233095 |
| HMGCS1 | 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble) | 0.0233004 |
| ZRANB2 | zinc finger, RAN-binding domain containing 2 | 0.0232948 |
| RPS6KC1 | ribosomal protein S6 kinase, 52kDa, polypeptide 1 | 0.0232098 |
| TCEA1 | transcription elongation factor A (SII), 1 | 0.0229242 |
| ELP2 | elongator acetyltransferase complex subunit 2 | 0.0228144 |
| FAR1 | fatty acyl CoA reductase 1 | 0.0228019 |
| ATP5F1A | ATP synthase F1 subunit alpha | 0.0227762 |
| ENOX1 | ecto-NOX disulfide-thiol exchanger 1 | 0.0225532 |
| WSB1 | WD repeat and SOCS box containing 1 | 0.022195 |
| HSD17B12 | hydroxysteroid (17-beta) dehydrogenase 12 | 0.0220637 |
| DDIT4 | DNA-damage-inducible transcript 4 | 0.0220324 |
| SESN2 | sestrin 2 | 0.0217009 |
| CCNT2 | cyclin T2 | 0.021625 |
| Symbol | Name | Standardized Value |
|---|---|---|
| PTMA | prothymosin, alpha | -0.29643 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.231545 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.169147 |
| ADAM10 | ADAM metallopeptidase domain 10 | -0.11327 |
| PKM | pyruvate kinase, muscle | -0.112557 |
| MINDY2 | MINDY lysine 48 deubiquitinase 2 | -0.100183 |
| AHNAK | AHNAK nucleoprotein | -0.090569 |
| ACTG1 | actin gamma 1 | -0.0842923 |
| RPS2 | ribosomal protein S2 | -0.081579 |
| CCND1 | cyclin D1 | -0.0720847 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0687029 |
| EIF4A2 | eukaryotic translation initiation factor 4A2 | -0.0646361 |
| BMP10 | bone morphogenetic protein 10 | -0.0635893 |
| MKI67 | marker of proliferation Ki-67 | -0.0603825 |
| EGFR | epidermal growth factor receptor | -0.0557097 |
| TEAD1 | TEA domain family member 1 (SV40 transcriptional enhancer factor) | -0.0552375 |
| MYO5C | myosin VC | -0.0544943 |
| IFI16 | interferon, gamma-inducible protein 16 | -0.0503918 |
| RPS8 | ribosomal protein S8 | -0.0466285 |
| SLC38A2 | solute carrier family 38, member 2 | -0.0463345 |
| ANXA1 | annexin A1 | -0.0444695 |
| RPS6 | ribosomal protein S6 | -0.042642 |
| ERC2 | ELKS/RAB6-interacting/CAST family member 2 | -0.0422045 |
| SPTAN1 | spectrin, alpha, non-erythrocytic 1 | -0.0421743 |
| SPATS2L | spermatogenesis associated, serine-rich 2-like | -0.0401723 |
| GLI3 | GLI family zinc finger 3 | -0.0399399 |
| BRD2 | bromodomain containing 2 | -0.039225 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | -0.038803 |
| FLNB | filamin B, beta | -0.0376791 |
| S100A10 | S100 calcium binding protein A10 | -0.037367 |
| SERPINB1 | serpin peptidase inhibitor, clade B (ovalbumin), member 1 | -0.0373095 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | -0.0368415 |
| GLI2 | GLI family zinc finger 2 | -0.0363837 |
| TPM4 | tropomyosin 4 | -0.0359726 |
| ALDH3A2 | aldehyde dehydrogenase 3 family, member A2 | -0.0357863 |
| CITED2 | Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2 | -0.0349607 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.034822 |
| SOS1 | son of sevenless homolog 1 (Drosophila) | -0.0346432 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.0344776 |
| DIAPH3 | diaphanous-related formin 3 | -0.0332042 |
| UBC | ubiquitin C | -0.0328623 |
| TAOK1 | TAO kinase 1 | -0.0327624 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0326379 |
| BMP2K | BMP2 inducible kinase | -0.0323179 |
| HSPA8 | heat shock 70kDa protein 8 | -0.0322432 |
| USP34 | ubiquitin specific peptidase 34 | -0.0318838 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | -0.0317872 |
| ALDH1A2 | aldehyde dehydrogenase 1 family, member A2 | -0.0314297 |
| RPL19 | ribosomal protein L19 | -0.0314206 |
| FOXP1 | forkhead box P1 | -0.031407 |
| TXNRD1 | thioredoxin reductase 1 | -0.0301799 |
| SPRY4 | sprouty homolog 4 (Drosophila) | -0.0294883 |
| PARP4 | poly (ADP-ribose) polymerase family, member 4 | -0.0294841 |
| PFN1 | profilin 1 | -0.0293709 |
| BNIP3 | BCL2/adenovirus E1B 19kDa interacting protein 3 | -0.028723 |
| CENPF | centromere protein F, 350/400kDa | -0.0285599 |
| RPL3 | ribosomal protein L3 | -0.028471 |
| SPRY1 | sprouty homolog 1, antagonist of FGF signaling (Drosophila) | -0.0274725 |
| CYB5B | cytochrome b5 type B (outer mitochondrial membrane) | -0.0272319 |
| PRG2 | proteoglycan 2, bone marrow (natural killer cell activator, eosinophil granule major basic protein) | -0.0272155 |
| ASPM | asp (abnormal spindle) homolog, microcephaly associated (Drosophila) | -0.0271092 |
| RPL7 | ribosomal protein L7 | -0.0270506 |
| NCEH1 | neutral cholesterol ester hydrolase 1 | -0.0267947 |
| RPL26 | ribosomal protein L26 | -0.0258844 |
| DUSP4 | dual specificity phosphatase 4 | -0.0258131 |
| BPTF | bromodomain PHD finger transcription factor | -0.0257775 |
| TAS2R14 | taste receptor, type 2, member 14 | -0.0257069 |
| RPL7A | ribosomal protein L7a | -0.0256482 |
| FER | fer (fps/fes related) tyrosine kinase | -0.0252908 |
| ARHGEF10 | Rho guanine nucleotide exchange factor (GEF) 10 | -0.0250981 |
| SPIDR | scaffolding protein involved in DNA repair | -0.0249873 |
| CREB5 | cAMP responsive element binding protein 5 | -0.0248268 |
| CUX1 | cut-like homeobox 1 | -0.0248156 |
| MAP1LC3B | microtubule-associated protein 1 light chain 3 beta | -0.0245408 |
| ARL4C | ADP-ribosylation factor-like 4C | -0.0244586 |
| S100A11 | S100 calcium binding protein A11 | -0.0243715 |
| NIPBL | Nipped-B homolog (Drosophila) | -0.0243541 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | -0.0241895 |
| RAB10 | RAB10, member RAS oncogene family | -0.0241112 |
| TRPC4AP | transient receptor potential cation channel, subfamily C, member 4 associated protein | -0.0239514 |
| CREBBP | CREB binding protein | -0.0238941 |
| GCLM | glutamate-cysteine ligase, modifier subunit | -0.0235192 |
| TRIM24 | tripartite motif containing 24 | -0.0232553 |
| NIN | ninein (GSK3B interacting protein) | -0.0232271 |
| DGKH | diacylglycerol kinase, eta | -0.0231751 |
| POTEF | POTE ankyrin domain family, member F | -0.0231402 |
| LOC102724023 | ES1 protein homolog, mitochondrial | -0.0229526 |
| RPL34 | ribosomal protein L34 | -0.0229005 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.0228084 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.0227742 |
| NMD3 | NMD3 ribosome export adaptor | -0.022467 |
| MYO9A | myosin IXA | -0.0224094 |
| RPL8 | ribosomal protein L8 | -0.0223371 |
| TMCO3 | transmembrane and coiled-coil domains 3 | -0.0223306 |
| SP100 | SP100 nuclear antigen | -0.0222409 |
| WNK1 | WNK lysine deficient protein kinase 1 | -0.0221826 |
| SDK1 | sidekick cell adhesion molecule 1 | -0.0221584 |
| ANO6 | anoctamin 6 | -0.0221253 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | -0.0217962 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | -0.021791 |
