| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | (S)-Crizotinib perturbation in SW 1271 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the (S)-Crizotinib_SW 1271 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| NAMPT | nicotinamide phosphoribosyltransferase | 0.101799 |
| PKM | pyruvate kinase, muscle | 0.0940304 |
| ZNF292 | zinc finger protein 292 | 0.0860813 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | 0.0790042 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | 0.0722598 |
| LDHA | lactate dehydrogenase A | 0.0695172 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | 0.0672136 |
| GOLGA4 | golgin A4 | 0.066582 |
| RBM25 | RNA binding motif protein 25 | 0.0642757 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.0641045 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0633155 |
| SLC2A3 | solute carrier family 2 (facilitated glucose transporter), member 3 | 0.0631794 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | 0.0622973 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0580112 |
| TBL1XR1 | transducin (beta)-like 1 X-linked receptor 1 | 0.0577804 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0567445 |
| WDR43 | WD repeat domain 43 | 0.0536015 |
| MSN | moesin | 0.0529179 |
| BIRC3 | baculoviral IAP repeat containing 3 | 0.0509061 |
| IGFBP3 | insulin-like growth factor binding protein 3 | 0.0501076 |
| ACSL3 | acyl-CoA synthetase long-chain family member 3 | 0.0494258 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.0490901 |
| PHF3 | PHD finger protein 3 | 0.0468865 |
| ELL2 | elongation factor, RNA polymerase II, 2 | 0.0463732 |
| ANKRD12 | ankyrin repeat domain 12 | 0.0462427 |
| SEPTIN2 | septin 2 | 0.0459054 |
| THSD4 | thrombospondin, type I, domain containing 4 | 0.0450539 |
| DST | dystonin | 0.0448075 |
| ATP13A3 | ATPase type 13A3 | 0.044258 |
| WAC | WW domain containing adaptor with coiled-coil | 0.0421826 |
| GAPVD1 | GTPase activating protein and VPS9 domains 1 | 0.0413523 |
| PUM2 | pumilio RNA-binding family member 2 | 0.0410503 |
| SOD2 | superoxide dismutase 2, mitochondrial | 0.0403759 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | 0.0396482 |
| MPP2 | membrane protein, palmitoylated 2 (MAGUK p55 subfamily member 2) | 0.0393001 |
| PDE8A | phosphodiesterase 8A | 0.0384197 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0372942 |
| RNF145 | ring finger protein 145 | 0.0371393 |
| LRBA | LPS-responsive vesicle trafficking, beach and anchor containing | 0.0368535 |
| MAP3K20 | mitogen-activated protein kinase kinase kinase 20 | 0.0368068 |
| SSRP1 | structure specific recognition protein 1 | 0.0359369 |
| TMEM39A | transmembrane protein 39A | 0.0356741 |
| ATP2B1 | ATPase, Ca++ transporting, plasma membrane 1 | 0.0355611 |
| PTK2 | protein tyrosine kinase 2 | 0.0354646 |
| CDCP1 | CUB domain containing protein 1 | 0.0353658 |
| INSIG1 | insulin induced gene 1 | 0.035359 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0351431 |
| ZNF148 | zinc finger protein 148 | 0.0350379 |
| UBE2D2 | ubiquitin-conjugating enzyme E2D 2 | 0.0348868 |
| NPTN | neuroplastin | 0.03477 |
| DHX9 | DEAH (Asp-Glu-Ala-His) box helicase 9 | 0.0346007 |
| PIK3C2A | phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 alpha | 0.0341317 |
| HSPH1 | heat shock 105kDa/110kDa protein 1 | 0.0341184 |
| TBC1D5 | TBC1 domain family, member 5 | 0.034075 |
| RBM27 | RNA binding motif protein 27 | 0.0340703 |
| CDC42BPB | CDC42 binding protein kinase beta (DMPK-like) | 0.0340187 |
| MORF4L1 | mortality factor 4 like 1 | 0.0337516 |
| IGF2BP3 | insulin-like growth factor 2 mRNA binding protein 3 | 0.0331466 |
| FLNB | filamin B, beta | 0.0326352 |
| ARHGEF28 | Rho guanine nucleotide exchange factor (GEF) 28 | 0.0325509 |
| RAD23B | RAD23 homolog B (S. cerevisiae) | 0.0325454 |
| SERINC1 | serine incorporator 1 | 0.0323461 |
| APBB2 | amyloid beta (A4) precursor protein-binding, family B, member 2 | 0.0322384 |
| ICAM1 | intercellular adhesion molecule 1 | 0.0320348 |
| ZNF644 | zinc finger protein 644 | 0.0316412 |
| DYNC1H1 | dynein, cytoplasmic 1, heavy chain 1 | 0.0315372 |
| NCKAP1 | NCK-associated protein 1 | 0.031343 |
| DGKD | diacylglycerol kinase, delta 130kDa | 0.0312896 |
| SREK1 | splicing regulatory glutamine/lysine-rich protein 1 | 0.0311433 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | 0.0311384 |
| UGCG | UDP-glucose ceramide glucosyltransferase | 0.0309583 |
| GTDC1 | glycosyltransferase-like domain containing 1 | 0.0309071 |
| TPM4 | tropomyosin 4 | 0.0308433 |
| AASDHPPT | aminoadipate-semialdehyde dehydrogenase-phosphopantetheinyl transferase | 0.0308067 |
| ARPP19 | cAMP-regulated phosphoprotein, 19kDa | 0.0306773 |
| PGK1 | phosphoglycerate kinase 1 | 0.0306642 |
| UACA | uveal autoantigen with coiled-coil domains and ankyrin repeats | 0.0305263 |
| TFG | TRK-fused gene | 0.0303093 |
| TPD52 | tumor protein D52 | 0.0302359 |
| DENND4A | DENN/MADD domain containing 4A | 0.0300232 |
| TXNRD1 | thioredoxin reductase 1 | 0.0299336 |
| RCOR1 | REST corepressor 1 | 0.0291288 |
| OSMR | oncostatin M receptor | 0.0291062 |
| MTMR2 | myotubularin related protein 2 | 0.0290395 |
| BIRC2 | baculoviral IAP repeat containing 2 | 0.0289979 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0289472 |
| ICE1 | interactor of little elongation complex ELL subunit 1 | 0.0288245 |
| RAB1A | RAB1A, member RAS oncogene family | 0.0288101 |
| MYBL1 | v-myb avian myeloblastosis viral oncogene homolog-like 1 | 0.0287914 |
| SYNCRIP | synaptotagmin binding, cytoplasmic RNA interacting protein | 0.0286394 |
| ABI2 | abl-interactor 2 | 0.028523 |
| TOP1 | topoisomerase (DNA) I | 0.0284631 |
| SLC35E3 | solute carrier family 35, member E3 | 0.0284054 |
| DNER | delta/notch-like EGF repeat containing | 0.0283897 |
| EP400 | E1A binding protein p400 | 0.0280752 |
| SETD5 | SET domain containing 5 | 0.027327 |
| PARD3 | par-3 family cell polarity regulator | 0.0272657 |
| ARCN1 | archain 1 | 0.0268412 |
| RALGAPB | Ral GTPase activating protein, beta subunit (non-catalytic) | 0.0266839 |
| SPRED1 | sprouty-related, EVH1 domain containing 1 | 0.0266591 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.122541 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | -0.112924 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0598888 |
| SMC4 | structural maintenance of chromosomes 4 | -0.0581349 |
| CANX | calnexin | -0.0535544 |
| FUS | FUS RNA binding protein | -0.0533302 |
| HDLBP | high density lipoprotein binding protein | -0.0488743 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | -0.0476699 |
| SMYD3 | SET and MYND domain containing 3 | -0.0474848 |
| SLC4A7 | solute carrier family 4, sodium bicarbonate cotransporter, member 7 | -0.0472467 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | -0.0458466 |
| TMSB10 | thymosin beta 10 | -0.0454187 |
| NF1 | neurofibromin 1 | -0.0448766 |
| EGR1 | early growth response 1 | -0.0440463 |
| N4BP2L2 | NEDD4 binding protein 2-like 2 | -0.0421644 |
| HMGA2 | high mobility group AT-hook 2 | -0.0407236 |
| ATXN1 | ataxin 1 | -0.0402968 |
| IFIT2 | interferon-induced protein with tetratricopeptide repeats 2 | -0.0402009 |
| MKI67 | marker of proliferation Ki-67 | -0.0399189 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.0397982 |
| ILF3 | interleukin enhancer binding factor 3, 90kDa | -0.0388833 |
| MARCKS | myristoylated alanine-rich protein kinase C substrate | -0.0379234 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0371096 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | -0.036327 |
| ARHGAP26 | Rho GTPase activating protein 26 | -0.0359477 |
| INTS6 | integrator complex subunit 6 | -0.0357523 |
| RDX | radixin | -0.0350607 |
| OASL | 2'-5'-oligoadenylate synthetase-like | -0.0349819 |
| EPC2 | enhancer of polycomb homolog 2 (Drosophila) | -0.0345825 |
| CBFA2T2 | core-binding factor, runt domain, alpha subunit 2; translocated to, 2 | -0.0340818 |
| KPNA4 | karyopherin alpha 4 (importin alpha 3) | -0.0340306 |
| ANLN | anillin, actin binding protein | -0.0339626 |
| NIPBL | Nipped-B homolog (Drosophila) | -0.0339015 |
| DTNA | dystrobrevin, alpha | -0.0334287 |
| FNBP1 | formin binding protein 1 | -0.0333886 |
| RPS19 | ribosomal protein S19 | -0.0333436 |
| OGA | O-GlcNAcase | -0.0329253 |
| CUL3 | cullin 3 | -0.0328785 |
| IFIH1 | interferon induced with helicase C domain 1 | -0.0326719 |
| IGF2BP2 | insulin-like growth factor 2 mRNA binding protein 2 | -0.0326087 |
| NCAPD2 | non-SMC condensin I complex, subunit D2 | -0.0325663 |
| SMC5 | structural maintenance of chromosomes 5 | -0.0323332 |
| DPYD | dihydropyrimidine dehydrogenase | -0.032259 |
| AKAP10 | A kinase (PRKA) anchor protein 10 | -0.0322138 |
| RPS11 | ribosomal protein S11 | -0.031932 |
| WNK1 | WNK lysine deficient protein kinase 1 | -0.0318127 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | -0.0317779 |
| AFF4 | AF4/FMR2 family, member 4 | -0.0316465 |
| ZFAND3 | zinc finger, AN1-type domain 3 | -0.0316158 |
| SGO2 | shugoshin 2 | -0.0315358 |
| BUB1 | BUB1 mitotic checkpoint serine/threonine kinase | -0.0310599 |
| RPL27A | ribosomal protein L27a | -0.0309754 |
| ERC2 | ELKS/RAB6-interacting/CAST family member 2 | -0.030887 |
| MT2A | metallothionein 2A | -0.0308584 |
| CCDC91 | coiled-coil domain containing 91 | -0.0306868 |
| POLR2A | polymerase (RNA) II (DNA directed) polypeptide A, 220kDa | -0.0306452 |
| RPL19 | ribosomal protein L19 | -0.0304729 |
| GNAQ | guanine nucleotide binding protein (G protein), q polypeptide | -0.0303523 |
| FNDC3A | fibronectin type III domain containing 3A | -0.0302672 |
| HNRNPC | heterogeneous nuclear ribonucleoprotein C (C1/C2) | -0.0301592 |
| H3-3B | H3.3 histone B | -0.0300039 |
| C6ORF62 | chromosome 6 open reading frame 62 | -0.0298782 |
| BBX | bobby sox homolog (Drosophila) | -0.0298719 |
| DHX36 | DEAH (Asp-Glu-Ala-His) box polypeptide 36 | -0.0298489 |
| ACTN4 | actinin, alpha 4 | -0.0293117 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | -0.0292779 |
| MAP4K3 | mitogen-activated protein kinase kinase kinase kinase 3 | -0.0289453 |
| EMSY | EMSY transcriptional repressor, BRCA2 interacting | -0.0289252 |
| RPLP1 | ribosomal protein, large, P1 | -0.0285163 |
| NLK | nemo-like kinase | -0.0285084 |
| GPATCH2L | G patch domain containing 2-like | -0.0285051 |
| PLEKHA8 | pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 8 | -0.0282329 |
| RSRP1 | arginine/serine-rich protein 1 | -0.0281921 |
| PDIA4 | protein disulfide isomerase family A, member 4 | -0.0280208 |
| NR1D2 | nuclear receptor subfamily 1, group D, member 2 | -0.0280138 |
| RORA | RAR-related orphan receptor A | -0.0280102 |
| TAS2R14 | taste receptor, type 2, member 14 | -0.0279551 |
| TRPM7 | transient receptor potential cation channel, subfamily M, member 7 | -0.0279315 |
| RALGAPA1 | Ral GTPase activating protein, alpha subunit 1 (catalytic) | -0.0277669 |
| KCNN4 | potassium channel, calcium activated intermediate/small conductance subfamily N alpha, member 4 | -0.0277214 |
| PAN3 | PAN3 poly(A) specific ribonuclease subunit | -0.0276121 |
| ACTR2 | ARP2 actin-related protein 2 homolog (yeast) | -0.0274787 |
| MIS18BP1 | MIS18 binding protein 1 | -0.02728 |
| GLCCI1 | glucocorticoid induced 1 | -0.0271542 |
| NUP214 | nucleoporin 214kDa | -0.026784 |
| CDK19 | cyclin-dependent kinase 19 | -0.0264739 |
| IFIT3 | interferon-induced protein with tetratricopeptide repeats 3 | -0.0264336 |
| GNAS | GNAS complex locus | -0.0263669 |
| TRA2A | transformer 2 alpha homolog (Drosophila) | -0.02579 |
| FBXO11 | F-box protein 11 | -0.0256949 |
| PDCD10 | programmed cell death 10 | -0.0256094 |
| CDK13 | cyclin-dependent kinase 13 | -0.025608 |
| KIAA1328 | KIAA1328 | -0.0253902 |
| BMERB1 | bMERB domain containing 1 | -0.0253664 |
| HIPK2 | homeodomain interacting protein kinase 2 | -0.0251813 |
| PURA | purine-rich element binding protein A | -0.0251298 |
| PRG2 | proteoglycan 2, bone marrow (natural killer cell activator, eosinophil granule major basic protein) | -0.0251014 |
| RICTOR | RPTOR independent companion of MTOR, complex 2 | -0.0250185 |
| NUMA1 | nuclear mitotic apparatus protein 1 | -0.0249055 |
| CDH4 | cadherin 4, type 1, R-cadherin (retinal) | -0.024899 |
