| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | (S)-Crizotinib perturbation in SW 900 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the (S)-Crizotinib_SW 900 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.130271 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | 0.117706 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | 0.0882599 |
| VEGFA | vascular endothelial growth factor A | 0.0834389 |
| PLIN2 | perilipin 2 | 0.0829702 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0770096 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0704051 |
| CD109 | CD109 molecule | 0.0687881 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.0680664 |
| CENPF | centromere protein F, 350/400kDa | 0.0640865 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.0634582 |
| GOLGA4 | golgin A4 | 0.0622347 |
| SUCO | SUN domain containing ossification factor | 0.0609334 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | 0.0567232 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | 0.0536285 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.0531922 |
| SEC23A | Sec23 homolog A (S. cerevisiae) | 0.0512118 |
| TXNIP | thioredoxin interacting protein | 0.0512018 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | 0.050781 |
| ESYT2 | extended synaptotagmin-like protein 2 | 0.0505691 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.0502412 |
| ENO2 | enolase 2 (gamma, neuronal) | 0.0492469 |
| LOC102724023 | ES1 protein homolog, mitochondrial | 0.0475292 |
| HMGCS1 | 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble) | 0.0464582 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.0458223 |
| COPA | coatomer protein complex, subunit alpha | 0.044692 |
| STC2 | stanniocalcin 2 | 0.0438171 |
| NDRG1 | N-myc downstream regulated 1 | 0.0438142 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | 0.0435452 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0428525 |
| IBTK | inhibitor of Bruton agammaglobulinemia tyrosine kinase | 0.042687 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | 0.042184 |
| INSIG1 | insulin induced gene 1 | 0.0421543 |
| TTC3 | tetratricopeptide repeat domain 3 | 0.0417865 |
| SEC31A | SEC31 homolog A (S. cerevisiae) | 0.0417389 |
| BIRC6 | baculoviral IAP repeat containing 6 | 0.0413293 |
| PCBP2 | poly(rC) binding protein 2 | 0.0408789 |
| BLZF1 | basic leucine zipper nuclear factor 1 | 0.0408067 |
| ELL2 | elongation factor, RNA polymerase II, 2 | 0.0391773 |
| ACBD3 | acyl-CoA binding domain containing 3 | 0.0387701 |
| FDPS | farnesyl diphosphate synthase | 0.0386832 |
| SCFD2 | sec1 family domain containing 2 | 0.0385546 |
| FAM13A | family with sequence similarity 13, member A | 0.0375877 |
| POTEF | POTE ankyrin domain family, member F | 0.0370704 |
| PICALM | phosphatidylinositol binding clathrin assembly protein | 0.035979 |
| RPS6KC1 | ribosomal protein S6 kinase, 52kDa, polypeptide 1 | 0.0359611 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | 0.0348011 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | 0.0347423 |
| ATP2B1 | ATPase, Ca++ transporting, plasma membrane 1 | 0.0346812 |
| GPC6 | glypican 6 | 0.0346581 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | 0.0346013 |
| TMF1 | TATA element modulatory factor 1 | 0.0344445 |
| EZR | ezrin | 0.034365 |
| AFDN | afadin, adherens junction formation factor | 0.0337502 |
| ZCCHC7 | zinc finger, CCHC domain containing 7 | 0.033254 |
| LDHA | lactate dehydrogenase A | 0.0329826 |
| RTN4 | reticulon 4 | 0.032842 |
| ARF4 | ADP-ribosylation factor 4 | 0.0326652 |
| SLC2A3 | solute carrier family 2 (facilitated glucose transporter), member 3 | 0.0325745 |
| MBNL1 | muscleblind-like splicing regulator 1 | 0.0321209 |
| ZNF292 | zinc finger protein 292 | 0.0312778 |
| RAB6A | RAB6A, member RAS oncogene family | 0.0305896 |
| MRPS6 | mitochondrial ribosomal protein S6 | 0.0305189 |
| GOLPH3 | golgi phosphoprotein 3 (coat-protein) | 0.0304716 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0299527 |
| TBC1D8 | TBC1 domain family, member 8 (with GRAM domain) | 0.0297213 |
| CCNL1 | cyclin L1 | 0.0289907 |
| RSF1 | remodeling and spacing factor 1 | 0.0287937 |
| NUP58 | nucleoporin 58 | 0.0287078 |
| MAPKAPK2 | mitogen-activated protein kinase-activated protein kinase 2 | 0.0284828 |
| INSIG2 | insulin induced gene 2 | 0.02834 |
| ADIPOR2 | adiponectin receptor 2 | 0.0283386 |
| RNMT | RNA (guanine-7-) methyltransferase | 0.0281844 |
| CALU | calumenin | 0.028099 |
| MORF4L2 | mortality factor 4 like 2 | 0.0280127 |
| COG5 | component of oligomeric golgi complex 5 | 0.0277666 |
| ADAM17 | ADAM metallopeptidase domain 17 | 0.0275158 |
| SEC24A | SEC24 family member A | 0.0275097 |
| EPRS1 | glutamyl-prolyl-tRNA synthetase 1 | 0.0274862 |
| TM9SF3 | transmembrane 9 superfamily member 3 | 0.0270879 |
| SRP54 | signal recognition particle 54kDa | 0.026999 |
| HDGF | hepatoma-derived growth factor | 0.0269573 |
| TES | testin LIM domain protein | 0.0268947 |
| TPM3 | tropomyosin 3 | 0.0267495 |
| WDFY2 | WD repeat and FYVE domain containing 2 | 0.026687 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | 0.0266529 |
| CARD16 | caspase recruitment domain family, member 16 | 0.0264047 |
| PTPN14 | protein tyrosine phosphatase, non-receptor type 14 | 0.0263513 |
| RAB18 | RAB18, member RAS oncogene family | 0.0260862 |
| BCLAF1 | BCL2-associated transcription factor 1 | 0.0258211 |
| LCOR | ligand dependent nuclear receptor corepressor | 0.0255981 |
| PDXDC1 | pyridoxal-dependent decarboxylase domain containing 1 | 0.0253588 |
| KDM6A | lysine (K)-specific demethylase 6A | 0.025294 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0251763 |
| FOSB | FBJ murine osteosarcoma viral oncogene homolog B | 0.0251299 |
| MSN | moesin | 0.0251051 |
| HSPA9 | heat shock 70kDa protein 9 (mortalin) | 0.0248979 |
| PAPOLA | poly(A) polymerase alpha | 0.0248728 |
| COG6 | component of oligomeric golgi complex 6 | 0.0248054 |
| FOSL1 | FOS-like antigen 1 | 0.0246973 |
| Symbol | Name | Standardized Value |
|---|---|---|
| PTGS2 | prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) | -0.297853 |
| FN1 | fibronectin 1 | -0.266709 |
| NRG1 | neuregulin 1 | -0.188295 |
| CYP1B1 | cytochrome P450, family 1, subfamily B, polypeptide 1 | -0.159392 |
| HMGA2 | high mobility group AT-hook 2 | -0.144871 |
| GLIS3 | GLIS family zinc finger 3 | -0.126533 |
| HLA-B | major histocompatibility complex, class I, B | -0.0874079 |
| CANX | calnexin | -0.0713704 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | -0.0661322 |
| SQSTM1 | sequestosome 1 | -0.0643856 |
| TMSB10 | thymosin beta 10 | -0.0536918 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0525253 |
| VCL | vinculin | -0.0518028 |
| ASPH | aspartate beta-hydroxylase | -0.0498452 |
| INTS6 | integrator complex subunit 6 | -0.0486861 |
| FNBP1 | formin binding protein 1 | -0.0458694 |
| PTMA | prothymosin, alpha | -0.0446476 |
| EXT1 | exostosin glycosyltransferase 1 | -0.0428734 |
| RPL26 | ribosomal protein L26 | -0.0389255 |
| RPS21 | ribosomal protein S21 | -0.0385141 |
| AEBP2 | AE binding protein 2 | -0.0375741 |
| RPS24 | ribosomal protein S24 | -0.0364309 |
| RPS19 | ribosomal protein S19 | -0.0359531 |
| IER3 | immediate early response 3 | -0.0350821 |
| FAM20C | family with sequence similarity 20, member C | -0.0349793 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | -0.0348561 |
| TMSB4X | thymosin beta 4, X-linked | -0.0344473 |
| ARF1 | ADP-ribosylation factor 1 | -0.0344183 |
| NCOA7 | nuclear receptor coactivator 7 | -0.033299 |
| RPL35A | ribosomal protein L35a | -0.0326992 |
| DNAH5 | dynein, axonemal, heavy chain 5 | -0.0311842 |
| RPL34 | ribosomal protein L34 | -0.0308996 |
| DDX5 | DEAD (Asp-Glu-Ala-Asp) box helicase 5 | -0.030876 |
| CRK | v-crk avian sarcoma virus CT10 oncogene homolog | -0.0306011 |
| SPIDR | scaffolding protein involved in DNA repair | -0.0305123 |
| POLR2A | polymerase (RNA) II (DNA directed) polypeptide A, 220kDa | -0.030435 |
| IFI16 | interferon, gamma-inducible protein 16 | -0.0299398 |
| MT2A | metallothionein 2A | -0.0299012 |
| UGDH | UDP-glucose 6-dehydrogenase | -0.0296659 |
| TAF1D | TATA box binding protein (TBP)-associated factor, RNA polymerase I, D, 41kDa | -0.0295659 |
| GNAS | GNAS complex locus | -0.0289908 |
| B4GALT5 | UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 5 | -0.0288871 |
| RPL37A | ribosomal protein L37a | -0.0286181 |
| PLCB1 | phospholipase C, beta 1 (phosphoinositide-specific) | -0.028568 |
| RAB31 | RAB31, member RAS oncogene family | -0.0285082 |
| RPH3AL | rabphilin 3A-like (without C2 domains) | -0.0282922 |
| BASP1 | brain abundant, membrane attached signal protein 1 | -0.0279545 |
| H1-0 | H1.0 linker histone | -0.0278999 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | -0.0278349 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | -0.0267002 |
| SDC4 | syndecan 4 | -0.0266801 |
| RIGI | RNA sensor RIG-I | -0.026529 |
| RPS29 | ribosomal protein S29 | -0.0263186 |
| MCTP2 | multiple C2 domains, transmembrane 2 | -0.0262934 |
| RPLP1 | ribosomal protein, large, P1 | -0.0261323 |
| NHS | Nance-Horan syndrome (congenital cataracts and dental anomalies) | -0.0259045 |
| LRRC23 | leucine rich repeat containing 23 | -0.0254225 |
| IFI6 | interferon, alpha-inducible protein 6 | -0.0252406 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | -0.0251292 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | -0.024955 |
| CAB39 | calcium binding protein 39 | -0.0246113 |
| NPR2 | natriuretic peptide receptor 2 | -0.0246054 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | -0.0245808 |
| RPS11 | ribosomal protein S11 | -0.0244602 |
| BICD1 | bicaudal D homolog 1 (Drosophila) | -0.0243789 |
| HDLBP | high density lipoprotein binding protein | -0.0240845 |
| ABCC3 | ATP-binding cassette, sub-family C (CFTR/MRP), member 3 | -0.0240738 |
| FHL2 | four and a half LIM domains 2 | -0.0239328 |
| PALLD | palladin, cytoskeletal associated protein | -0.0237253 |
| AHRR | aryl-hydrocarbon receptor repressor | -0.0236475 |
| FOXP1 | forkhead box P1 | -0.023412 |
| RAB1A | RAB1A, member RAS oncogene family | -0.0233489 |
| ZNF217 | zinc finger protein 217 | -0.0233046 |
| EFNA5 | ephrin-A5 | -0.0230471 |
| RPS8 | ribosomal protein S8 | -0.0230215 |
| ACTN4 | actinin, alpha 4 | -0.0228901 |
| RPS27A | ribosomal protein S27a | -0.0228594 |
| TGFA | transforming growth factor, alpha | -0.022856 |
| RPL31 | ribosomal protein L31 | -0.0226785 |
| HS2ST1 | heparan sulfate 2-O-sulfotransferase 1 | -0.0226558 |
| OGA | O-GlcNAcase | -0.0226406 |
| PELO | pelota homolog (Drosophila) | -0.0219269 |
| SMAD3 | SMAD family member 3 | -0.0215732 |
| IFI27 | interferon, alpha-inducible protein 27 | -0.0215371 |
| AHNAK | AHNAK nucleoprotein | -0.0214596 |
| DUSP16 | dual specificity phosphatase 16 | -0.0214522 |
| RPL37 | ribosomal protein L37 | -0.0214063 |
| SDCBP | syndecan binding protein (syntenin) | -0.0213036 |
| RAD21 | RAD21 homolog (S. pombe) | -0.0212574 |
| CUX1 | cut-like homeobox 1 | -0.0210943 |
| NABP1 | nucleic acid binding protein 1 | -0.0209451 |
| WTAP | Wilms tumor 1 associated protein | -0.020934 |
| WSB1 | WD repeat and SOCS box containing 1 | -0.0208993 |
| ACSL4 | acyl-CoA synthetase long-chain family member 4 | -0.0207262 |
| STAU1 | staufen double-stranded RNA binding protein 1 | -0.0207261 |
| VIM | vimentin | -0.020637 |
| CHST15 | carbohydrate (N-acetylgalactosamine 4-sulfate 6-O) sulfotransferase 15 | -0.0205671 |
| LY6E | lymphocyte antigen 6 complex, locus E | -0.0205282 |
| LRMDA | leucine rich melanocyte differentiation associated | -0.0204026 |
| TUFT1 | tuftelin 1 | -0.0202614 |
