| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | γ-Oryzanol perturbation in A-172 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the γ-Oryzanol_A-172 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.182156 |
| ABCA1 | ATP-binding cassette, sub-family A (ABC1), member 1 | 0.121629 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | 0.115743 |
| SPARC | secreted protein, acidic, cysteine-rich (osteonectin) | 0.0891797 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | 0.0837761 |
| DLG1 | discs, large homolog 1 (Drosophila) | 0.0787833 |
| LOXL2 | lysyl oxidase-like 2 | 0.0602402 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.0574299 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0547954 |
| ELL2 | elongation factor, RNA polymerase II, 2 | 0.0514691 |
| NDRG1 | N-myc downstream regulated 1 | 0.0514306 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0508604 |
| UBC | ubiquitin C | 0.0497229 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | 0.0489005 |
| MYADM | myeloid-associated differentiation marker | 0.0480591 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.0479007 |
| IGFBP3 | insulin-like growth factor binding protein 3 | 0.0465348 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0435468 |
| FLNB | filamin B, beta | 0.0427176 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.04217 |
| PLAT | plasminogen activator, tissue | 0.0421176 |
| B2M | beta-2-microglobulin | 0.0413764 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0374354 |
| VEGFA | vascular endothelial growth factor A | 0.0360967 |
| OGA | O-GlcNAcase | 0.0347449 |
| CALR | calreticulin | 0.0344709 |
| OPTN | optineurin | 0.0324264 |
| ANKIB1 | ankyrin repeat and IBR domain containing 1 | 0.0323056 |
| FBN1 | fibrillin 1 | 0.0320461 |
| STC1 | stanniocalcin 1 | 0.0297963 |
| NAV2 | neuron navigator 2 | 0.0295601 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.029508 |
| FNIP1 | folliculin interacting protein 1 | 0.0295015 |
| UAP1 | UDP-N-acetylglucosamine pyrophosphorylase 1 | 0.0292614 |
| DSCAM | Down syndrome cell adhesion molecule | 0.028879 |
| SERPINE2 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 | 0.028861 |
| RTN4 | reticulon 4 | 0.0285351 |
| SBF2 | SET binding factor 2 | 0.0278594 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0276313 |
| IQGAP1 | IQ motif containing GTPase activating protein 1 | 0.0275787 |
| USP34 | ubiquitin specific peptidase 34 | 0.0275507 |
| DPYSL2 | dihydropyrimidinase-like 2 | 0.0273636 |
| SUCO | SUN domain containing ossification factor | 0.0268838 |
| MMP12 | matrix metallopeptidase 12 | 0.0265088 |
| SEPTIN9 | septin 9 | 0.0258934 |
| ARFGEF3 | ARFGEF family member 3 | 0.0256109 |
| FAM107B | family with sequence similarity 107, member B | 0.0251766 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0245357 |
| HSPA9 | heat shock 70kDa protein 9 (mortalin) | 0.024521 |
| COL8A1 | collagen, type VIII, alpha 1 | 0.0244755 |
| BACE2 | beta-site APP-cleaving enzyme 2 | 0.0243639 |
| APP | amyloid beta (A4) precursor protein | 0.0240969 |
| PRELID2 | PRELI domain containing 2 | 0.0240855 |
| MDM2 | MDM2 proto-oncogene, E3 ubiquitin protein ligase | 0.0240641 |
| EIF1 | eukaryotic translation initiation factor 1 | 0.023772 |
| GARS1 | glycyl-tRNA synthetase 1 | 0.0236627 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | 0.0233483 |
| MXI1 | MAX interactor 1, dimerization protein | 0.0231918 |
| SETD5 | SET domain containing 5 | 0.0230184 |
| ADM | adrenomedullin | 0.0230031 |
| NR3C1 | nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) | 0.0229422 |
| THBS2 | thrombospondin 2 | 0.0227444 |
| ARRDC3 | arrestin domain containing 3 | 0.0227364 |
| SOD2 | superoxide dismutase 2, mitochondrial | 0.0225806 |
| TNFRSF10B | tumor necrosis factor receptor superfamily, member 10b | 0.0225132 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | 0.0224963 |
| KLF6 | Kruppel-like factor 6 | 0.0221992 |
| KLF7 | Kruppel-like factor 7 (ubiquitous) | 0.0217608 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | 0.0217602 |
| KLHL24 | kelch-like family member 24 | 0.0214594 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | 0.0210661 |
| ZNF292 | zinc finger protein 292 | 0.0210497 |
| SH3BP5 | SH3-domain binding protein 5 (BTK-associated) | 0.0210275 |
| MAP4 | microtubule-associated protein 4 | 0.0208111 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | 0.0207149 |
| DSPP | dentin sialophosphoprotein | 0.0203647 |
| ZBTB20 | zinc finger and BTB domain containing 20 | 0.0202798 |
| HELZ | helicase with zinc finger | 0.0201656 |
| HUWE1 | HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase | 0.0201214 |
| ARHGEF10 | Rho guanine nucleotide exchange factor (GEF) 10 | 0.0199139 |
| UGCG | UDP-glucose ceramide glucosyltransferase | 0.0198071 |
| DST | dystonin | 0.019516 |
| GOLGA4 | golgin A4 | 0.0193688 |
| EGFR | epidermal growth factor receptor | 0.0192883 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.0192793 |
| ANXA2 | annexin A2 | 0.0192244 |
| PTK2 | protein tyrosine kinase 2 | 0.0191673 |
| SQSTM1 | sequestosome 1 | 0.0191328 |
| LOX | lysyl oxidase | 0.0189422 |
| VPS13C | vacuolar protein sorting 13 homolog C (S. cerevisiae) | 0.0189314 |
| PDIA6 | protein disulfide isomerase family A, member 6 | 0.0187995 |
| RNF24 | ring finger protein 24 | 0.018784 |
| PCBP2 | poly(rC) binding protein 2 | 0.0187018 |
| LIMCH1 | LIM and calponin homology domains 1 | 0.0184123 |
| DDIT4 | DNA-damage-inducible transcript 4 | 0.0183528 |
| YEATS2 | YEATS domain containing 2 | 0.0183216 |
| RUNX1 | runt-related transcription factor 1 | 0.0182747 |
| KMT2E | lysine (K)-specific methyltransferase 2E | 0.0182372 |
| MYOF | myoferlin | 0.0181918 |
| CYLD | cylindromatosis (turban tumor syndrome) | 0.0181468 |
| Symbol | Name | Standardized Value |
|---|---|---|
| TMSB10 | thymosin beta 10 | -0.107455 |
| PODXL | podocalyxin-like | -0.0583024 |
| KCNQ5 | potassium channel, voltage gated KQT-like subfamily Q, member 5 | -0.0461677 |
| S100A10 | S100 calcium binding protein A10 | -0.0427849 |
| COL5A1 | collagen, type V, alpha 1 | -0.0415503 |
| FN1 | fibronectin 1 | -0.0377431 |
| DIRAS3 | DIRAS family, GTP-binding RAS-like 3 | -0.03312 |
| RIGI | RNA sensor RIG-I | -0.0325979 |
| PRSS23 | protease, serine, 23 | -0.0316835 |
| MX2 | MX dynamin-like GTPase 2 | -0.030575 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | -0.0297713 |
| LMNA | lamin A/C | -0.0289712 |
| POTEF | POTE ankyrin domain family, member F | -0.0287622 |
| SAMD9 | sterile alpha motif domain containing 9 | -0.0279807 |
| CDH13 | cadherin 13 | -0.0269402 |
| ABI3BP | ABI family, member 3 (NESH) binding protein | -0.0264423 |
| RSAD2 | radical S-adenosyl methionine domain containing 2 | -0.0259849 |
| CACNA2D3 | calcium channel, voltage-dependent, alpha 2/delta subunit 3 | -0.0246415 |
| AHNAK | AHNAK nucleoprotein | -0.0242066 |
| ADAMTS6 | ADAM metallopeptidase with thrombospondin type 1 motif, 6 | -0.0241252 |
| PLXNA2 | plexin A2 | -0.0240836 |
| SUCNR1 | succinate receptor 1 | -0.0236943 |
| ISG15 | ISG15 ubiquitin-like modifier | -0.0232749 |
| S100A4 | S100 calcium binding protein A4 | -0.0230653 |
| MEIS2 | Meis homeobox 2 | -0.0229179 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0225662 |
| IFITM3 | interferon induced transmembrane protein 3 | -0.0221195 |
| HLA-B | major histocompatibility complex, class I, B | -0.0217709 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0215416 |
| MAP1B | microtubule-associated protein 1B | -0.0208137 |
| SORBS2 | sorbin and SH3 domain containing 2 | -0.0204819 |
| LHFPL2 | lipoma HMGIC fusion partner-like 2 | -0.0203153 |
| HLA-C | major histocompatibility complex, class I, C | -0.0197014 |
| CD59 | CD59 molecule, complement regulatory protein | -0.0196058 |
| NAV1 | neuron navigator 1 | -0.0187575 |
| IL7R | interleukin 7 receptor | -0.0187263 |
| IFITM1 | interferon induced transmembrane protein 1 | -0.0185278 |
| SMC4 | structural maintenance of chromosomes 4 | -0.018446 |
| ITGA3 | integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor) | -0.0182849 |
| IFI6 | interferon, alpha-inducible protein 6 | -0.0180121 |
| LRRC17 | leucine rich repeat containing 17 | -0.0173294 |
| COL5A2 | collagen, type V, alpha 2 | -0.0172565 |
| FRMD4A | FERM domain containing 4A | -0.0170614 |
| TPM1 | tropomyosin 1 (alpha) | -0.0169914 |
| GLIS3 | GLIS family zinc finger 3 | -0.0169831 |
| SP100 | SP100 nuclear antigen | -0.016976 |
| MED13L | mediator complex subunit 13-like | -0.0166814 |
| FLNA | filamin A, alpha | -0.0163534 |
| OASL | 2'-5'-oligoadenylate synthetase-like | -0.0162503 |
| RPL35A | ribosomal protein L35a | -0.0160514 |
| SLC38A1 | solute carrier family 38, member 1 | -0.0159841 |
| LDLRAD4 | low density lipoprotein receptor class A domain containing 4 | -0.0158169 |
| ACTG1 | actin gamma 1 | -0.0156628 |
| SAMD9L | sterile alpha motif domain containing 9-like | -0.015507 |
| TNS3 | tensin 3 | -0.0150159 |
| FBXL7 | F-box and leucine-rich repeat protein 7 | -0.0145883 |
| TRABD2B | TraB domain containing 2B | -0.0144049 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | -0.0142932 |
| TUBB4B | tubulin, beta 4B class IVb | -0.0142497 |
| HSPB1 | heat shock 27kDa protein 1 | -0.014068 |
| VEGFC | vascular endothelial growth factor C | -0.0140561 |
| CCND1 | cyclin D1 | -0.0137182 |
| IFIT3 | interferon-induced protein with tetratricopeptide repeats 3 | -0.0136509 |
| CDK6 | cyclin-dependent kinase 6 | -0.013361 |
| MBNL1 | muscleblind-like splicing regulator 1 | -0.0133581 |
| KRT81 | keratin 81, type II | -0.0133263 |
| DDX5 | DEAD (Asp-Glu-Ala-Asp) box helicase 5 | -0.0132938 |
| HS3ST3A1 | heparan sulfate (glucosamine) 3-O-sulfotransferase 3A1 | -0.0131082 |
| TUBB | tubulin, beta class I | -0.0129772 |
| RPL28 | ribosomal protein L28 | -0.0129197 |
| PMP22 | peripheral myelin protein 22 | -0.0127986 |
| IPO9 | importin 9 | -0.0127977 |
| TAGLN2 | transgelin 2 | -0.0127865 |
| NPR2 | natriuretic peptide receptor 2 | -0.0126225 |
| RACK1 | receptor for activated C kinase 1 | -0.0125768 |
| RPLP1 | ribosomal protein, large, P1 | -0.0125703 |
| HNRNPD | heterogeneous nuclear ribonucleoprotein D (AU-rich element RNA binding protein 1, 37kDa) | -0.0124725 |
| EDF1 | endothelial differentiation-related factor 1 | -0.0123427 |
| PSMA7 | proteasome (prosome, macropain) subunit, alpha type, 7 | -0.0123173 |
| DGKG | diacylglycerol kinase, gamma 90kDa | -0.0122973 |
| HERC6 | HECT and RLD domain containing E3 ubiquitin protein ligase family member 6 | -0.0122673 |
| WWTR1 | WW domain containing transcription regulator 1 | -0.0122528 |
| ECM1 | extracellular matrix protein 1 | -0.0122352 |
| PCDH7 | protocadherin 7 | -0.0121677 |
| RPS24 | ribosomal protein S24 | -0.0120752 |
| RPL19 | ribosomal protein L19 | -0.011953 |
| VAV2 | vav 2 guanine nucleotide exchange factor | -0.0119029 |
| NALF1 | NALCN channel auxiliary factor 1 | -0.0118751 |
| GSE1 | Gse1 coiled-coil protein | -0.01179 |
| CDH2 | cadherin 2, type 1, N-cadherin (neuronal) | -0.0117684 |
| IGFBP6 | insulin-like growth factor binding protein 6 | -0.0117682 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | -0.0117489 |
| FMN2 | formin 2 | -0.0114302 |
| ITPRIPL2 | inositol 1,4,5-trisphosphate receptor interacting protein-like 2 | -0.0114125 |
| FLT1 | fms-related tyrosine kinase 1 | -0.011288 |
| IFI16 | interferon, gamma-inducible protein 16 | -0.0110933 |
| HMGB1 | high mobility group box 1 | -0.0110729 |
| EFNA5 | ephrin-A5 | -0.0110104 |
| ZNF217 | zinc finger protein 217 | -0.0109858 |
| SCLT1 | sodium channel and clathrin linker 1 | -0.0109077 |