| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | γ-Oryzanol perturbation in HepG2/C3A cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the γ-Oryzanol_HepG2/C3A drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| IGF2 | insulin-like growth factor 2 | 0.256807 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | 0.197611 |
| SERPINA3 | serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 3 | 0.17466 |
| SERPINA1 | serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1 | 0.168197 |
| C3 | complement component 3 | 0.13274 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0810052 |
| DSPP | dentin sialophosphoprotein | 0.066295 |
| TF | transferrin | 0.0645185 |
| VEGFA | vascular endothelial growth factor A | 0.0616623 |
| FBF1 | Fas (TNFRSF6) binding factor 1 | 0.0561512 |
| CCL20 | chemokine (C-C motif) ligand 20 | 0.0551381 |
| LYZ | lysozyme | 0.0467537 |
| EIF3A | eukaryotic translation initiation factor 3, subunit A | 0.0464741 |
| PTTG1IP | pituitary tumor-transforming 1 interacting protein | 0.0427787 |
| VPS54 | vacuolar protein sorting 54 homolog (S. cerevisiae) | 0.0400136 |
| SRRM1 | serine/arginine repetitive matrix 1 | 0.0392516 |
| JMJD1C | jumonji domain containing 1C | 0.0390709 |
| KTN1 | kinectin 1 (kinesin receptor) | 0.0367217 |
| CPE | carboxypeptidase E | 0.0366992 |
| KIF5B | kinesin family member 5B | 0.0356317 |
| RBM25 | RNA binding motif protein 25 | 0.0333731 |
| ITPR2 | inositol 1,4,5-trisphosphate receptor, type 2 | 0.0322891 |
| EML4 | echinoderm microtubule associated protein like 4 | 0.031901 |
| CCNL1 | cyclin L1 | 0.0314334 |
| DDIT4 | DNA-damage-inducible transcript 4 | 0.0288669 |
| GPAM | glycerol-3-phosphate acyltransferase, mitochondrial | 0.0271556 |
| PSME4 | proteasome (prosome, macropain) activator subunit 4 | 0.0267858 |
| PTBP3 | polypyrimidine tract binding protein 3 | 0.0263399 |
| PRRC2C | proline-rich coiled-coil 2C | 0.0263219 |
| BHLHE40 | basic helix-loop-helix family, member e40 | 0.0262296 |
| ANXA5 | annexin A5 | 0.0259316 |
| RPS12 | ribosomal protein S12 | 0.0258874 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.024941 |
| TNFAIP3 | tumor necrosis factor, alpha-induced protein 3 | 0.0245003 |
| APOA2 | apolipoprotein A-II | 0.0244322 |
| PEG3 | paternally expressed 3 | 0.0243478 |
| RPS3 | ribosomal protein S3 | 0.0243433 |
| PTPRM | protein tyrosine phosphatase, receptor type, M | 0.0241991 |
| APOA1 | apolipoprotein A-I | 0.0241879 |
| SETD5 | SET domain containing 5 | 0.0234558 |
| MDM2 | MDM2 proto-oncogene, E3 ubiquitin protein ligase | 0.0230051 |
| ID2 | inhibitor of DNA binding 2, dominant negative helix-loop-helix protein | 0.0228673 |
| ATP1A4 | ATPase, Na+/K+ transporting, alpha 4 polypeptide | 0.0224794 |
| RPS6 | ribosomal protein S6 | 0.0223671 |
| TAX1BP1 | Tax1 (human T-cell leukemia virus type I) binding protein 1 | 0.0223331 |
| MAN1A1 | mannosidase, alpha, class 1A, member 1 | 0.0222463 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | 0.0221966 |
| NFKBIA | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha | 0.0220936 |
| FTL | ferritin, light polypeptide | 0.0215507 |
| PCM1 | pericentriolar material 1 | 0.0215212 |
| GOLGA4 | golgin A4 | 0.0211119 |
| EPB41L2 | erythrocyte membrane protein band 4.1-like 2 | 0.0208097 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.0201991 |
| MT2A | metallothionein 2A | 0.020044 |
| DSTN | destrin (actin depolymerizing factor) | 0.0194395 |
| APOB | apolipoprotein B | 0.01937 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | 0.0193313 |
| B2M | beta-2-microglobulin | 0.0190742 |
| NEDD9 | neural precursor cell expressed, developmentally down-regulated 9 | 0.0189639 |
| NACA | nascent polypeptide-associated complex alpha subunit | 0.0189376 |
| PPIG | peptidylprolyl isomerase G (cyclophilin G) | 0.0184859 |
| CAMK2N1 | calcium/calmodulin-dependent protein kinase II inhibitor 1 | 0.0184083 |
| BCLAF1 | BCL2-associated transcription factor 1 | 0.0181038 |
| ICAM1 | intercellular adhesion molecule 1 | 0.0180973 |
| ELL2 | elongation factor, RNA polymerase II, 2 | 0.0180835 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | 0.0180804 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | 0.0179394 |
| MATR3 | matrin 3 | 0.0177795 |
| RB1CC1 | RB1-inducible coiled-coil 1 | 0.0175849 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0175007 |
| SCAF11 | SR-related CTD-associated factor 11 | 0.0173006 |
| TMED2 | transmembrane emp24 domain trafficking protein 2 | 0.0169384 |
| WDR45B | WD repeat domain 45B | 0.016879 |
| PRAG1 | PEAK1 related, kinase-activating pseudokinase 1 | 0.0167967 |
| RPS2 | ribosomal protein S2 | 0.0167778 |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) | 0.0167599 |
| MKI67 | marker of proliferation Ki-67 | 0.0167022 |
| SF3B1 | splicing factor 3b, subunit 1, 155kDa | 0.016562 |
| SFTPA2 | surfactant protein A2 | 0.01656 |
| LSM14A | LSM14A, SCD6 homolog A (S. cerevisiae) | 0.0162416 |
| BTAF1 | BTAF1 RNA polymerase II, B-TFIID transcription factor-associated, 170kDa | 0.0158828 |
| OPTN | optineurin | 0.0157237 |
| MALT1 | MALT1 paracaspase | 0.0156808 |
| SLC23A1 | solute carrier family 23 (ascorbic acid transporter), member 1 | 0.0155888 |
| RPLP0 | ribosomal protein, large, P0 | 0.0155639 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0155066 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0154151 |
| DLC1 | DLC1 Rho GTPase activating protein | 0.0153314 |
| TLK1 | tousled-like kinase 1 | 0.0153215 |
| AMBRA1 | autophagy/beclin-1 regulator 1 | 0.0151386 |
| DENND4A | DENN/MADD domain containing 4A | 0.0151266 |
| LCOR | ligand dependent nuclear receptor corepressor | 0.0148521 |
| NCOR1 | nuclear receptor corepressor 1 | 0.0148416 |
| DNAJA2 | DnaJ (Hsp40) homolog, subfamily A, member 2 | 0.0147818 |
| RSRC2 | arginine/serine-rich coiled-coil 2 | 0.0145376 |
| KLF6 | Kruppel-like factor 6 | 0.0144684 |
| RICTOR | RPTOR independent companion of MTOR, complex 2 | 0.0144225 |
| A2M | alpha-2-macroglobulin | 0.014392 |
| PDS5A | PDS5 cohesin associated factor A | 0.0143412 |
| GSPT1 | G1 to S phase transition 1 | 0.0142995 |
| Symbol | Name | Standardized Value |
|---|---|---|
| AKAP12 | A kinase (PRKA) anchor protein 12 | -0.175576 |
| SAMD4A | sterile alpha motif domain containing 4A | -0.0957855 |
| ASPH | aspartate beta-hydroxylase | -0.0882641 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | -0.0838122 |
| ATXN1 | ataxin 1 | -0.0835062 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | -0.072561 |
| PLCB1 | phospholipase C, beta 1 (phosphoinositide-specific) | -0.0710633 |
| RPS27A | ribosomal protein S27a | -0.0703942 |
| GPC6 | glypican 6 | -0.0690604 |
| UBC | ubiquitin C | -0.0675305 |
| ENO1 | enolase 1, (alpha) | -0.066898 |
| FRMD5 | FERM domain containing 5 | -0.0667446 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.066334 |
| MAML2 | mastermind-like 2 (Drosophila) | -0.0654948 |
| GMDS | GDP-mannose 4,6-dehydratase | -0.0621715 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.0608541 |
| TMSB10 | thymosin beta 10 | -0.0592921 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0577913 |
| RERE | arginine-glutamic acid dipeptide (RE) repeats | -0.0575206 |
| PDLIM5 | PDZ and LIM domain 5 | -0.0559394 |
| MAGI2 | membrane associated guanylate kinase, WW and PDZ domain containing 2 | -0.0549688 |
| EHBP1 | EH domain binding protein 1 | -0.0491364 |
| SLC38A2 | solute carrier family 38, member 2 | -0.0480941 |
| NPAS2 | neuronal PAS domain protein 2 | -0.0478945 |
| LRMDA | leucine rich melanocyte differentiation associated | -0.04736 |
| AHNAK | AHNAK nucleoprotein | -0.0460042 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0394616 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | -0.0393215 |
| RPL23 | ribosomal protein L23 | -0.0388632 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0387485 |
| SVIL | supervillin | -0.0381027 |
| RNF213 | ring finger protein 213 | -0.0371884 |
| EXT1 | exostosin glycosyltransferase 1 | -0.0371816 |
| INTS6 | integrator complex subunit 6 | -0.0355657 |
| ATP10A | ATPase, class V, type 10A | -0.0355113 |
| DST | dystonin | -0.0354982 |
| IGFBP1 | insulin-like growth factor binding protein 1 | -0.0353623 |
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa | -0.0350492 |
| FAM107B | family with sequence similarity 107, member B | -0.0343718 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | -0.0339713 |
| GPC3 | glypican 3 | -0.0333443 |
| FLNB | filamin B, beta | -0.0332428 |
| CHST15 | carbohydrate (N-acetylgalactosamine 4-sulfate 6-O) sulfotransferase 15 | -0.0331053 |
| RIGI | RNA sensor RIG-I | -0.0327119 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.0325401 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | -0.0323601 |
| TRIO | trio Rho guanine nucleotide exchange factor | -0.0323586 |
| FMNL2 | formin-like 2 | -0.0323582 |
| JUN | jun proto-oncogene | -0.0322724 |
| SMAD3 | SMAD family member 3 | -0.0313727 |
| VCL | vinculin | -0.0294622 |
| MCL1 | myeloid cell leukemia 1 | -0.0294465 |
| MYH9 | myosin, heavy chain 9, non-muscle | -0.0293545 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | -0.0292841 |
| RAD51B | RAD51 paralog B | -0.0292537 |
| PRKCA | protein kinase C, alpha | -0.0290601 |
| DOCK4 | dedicator of cytokinesis 4 | -0.0290244 |
| HDAC4 | histone deacetylase 4 | -0.02862 |
| RPS24 | ribosomal protein S24 | -0.0285798 |
| FN1 | fibronectin 1 | -0.0275477 |
| LPP | LIM domain containing preferred translocation partner in lipoma | -0.0261997 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | -0.0258074 |
| KDM4C | lysine (K)-specific demethylase 4C | -0.0257433 |
| SUPT3H | suppressor of Ty 3 homolog (S. cerevisiae) | -0.0257194 |
| AGO2 | argonaute RISC catalytic component 2 | -0.0254418 |
| CANX | calnexin | -0.0253223 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.0252115 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | -0.02501 |
| EIF4G3 | eukaryotic translation initiation factor 4 gamma, 3 | -0.0248854 |
| DTNA | dystrobrevin, alpha | -0.0247846 |
| IGF1R | insulin-like growth factor 1 receptor | -0.0246297 |
| KDM3A | lysine (K)-specific demethylase 3A | -0.0245252 |
| FOXP1 | forkhead box P1 | -0.0244507 |
| SP100 | SP100 nuclear antigen | -0.0242166 |
| PLXDC2 | plexin domain containing 2 | -0.0241699 |
| EPAS1 | endothelial PAS domain protein 1 | -0.0233334 |
| TBC1D22A | TBC1 domain family, member 22A | -0.0231973 |
| ERN1 | endoplasmic reticulum to nucleus signaling 1 | -0.0231211 |
| ATP1B1 | ATPase, Na+/K+ transporting, beta 1 polypeptide | -0.023049 |
| SNTB1 | syntrophin, beta 1 (dystrophin-associated protein A1, 59kDa, basic component 1) | -0.0229166 |
| MX2 | MX dynamin-like GTPase 2 | -0.0226688 |
| DNAH17 | dynein, axonemal, heavy chain 17 | -0.0222821 |
| PARD3 | par-3 family cell polarity regulator | -0.0222713 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | -0.0221211 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | -0.0219076 |
| HMGA1 | high mobility group AT-hook 1 | -0.0215308 |
| MARCKS | myristoylated alanine-rich protein kinase C substrate | -0.0212588 |
| KIAA1217 | KIAA1217 | -0.0208462 |
| RPLP1 | ribosomal protein, large, P1 | -0.0205707 |
| EIF4A1 | eukaryotic translation initiation factor 4A1 | -0.0205247 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0202677 |
| ADARB1 | adenosine deaminase, RNA-specific, B1 | -0.0201529 |
| LRRTM4 | leucine rich repeat transmembrane neuronal 4 | -0.0200751 |
| GRB10 | growth factor receptor-bound protein 10 | -0.0198163 |
| PLIN2 | perilipin 2 | -0.0197032 |
| EIF2AK2 | eukaryotic translation initiation factor 2-alpha kinase 2 | -0.019589 |
| KYNU | kynureninase | -0.0195506 |
| KDM4B | lysine (K)-specific demethylase 4B | -0.019494 |
| FAT1 | FAT atypical cadherin 1 | -0.0194603 |
| NABP1 | nucleic acid binding protein 1 | -0.0192873 |
