γ-Oryzanol_Hs 766T Gene Set

Dataset Tahoe Therapeutics Tahoe 100M Perturbation Atlas
Category transcriptomics
Type cell type
Description γ-Oryzanol perturbation in Hs 766T cell line (Tahoe Therapeutics)
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Genes

200 genes differentially expressed following the γ-Oryzanol_Hs 766T drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.

increased expression

Symbol Name Standardized Value
ANXA1 annexin A1 0.150032
LMO7 LIM domain 7 0.104027
FLNB filamin B, beta 0.095675
KRT6A keratin 6A, type II 0.0945645
TRIO trio Rho guanine nucleotide exchange factor 0.0944991
MYOF myoferlin 0.0848995
HSP90B1 heat shock protein 90kDa beta (Grp94), member 1 0.0824712
EMP1 epithelial membrane protein 1 0.0741904
MTSS1 metastasis suppressor 1 0.0717386
EZR ezrin 0.0715361
NFATC2 nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 2 0.0640237
INTS6 integrator complex subunit 6 0.0615496
RAI14 retinoic acid induced 14 0.0613809
MBNL2 muscleblind-like splicing regulator 2 0.0602276
IL1RAPL1 interleukin 1 receptor accessory protein-like 1 0.0585801
MEF2A myocyte enhancer factor 2A 0.0582068
HSPA5 heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) 0.0570966
SLC35F3 solute carrier family 35, member F3 0.0539082
ASPH aspartate beta-hydroxylase 0.0538087
SEC31A SEC31 homolog A (S. cerevisiae) 0.0489575
EEF2 eukaryotic translation elongation factor 2 0.048924
KCNMA1 potassium channel, calcium activated large conductance subfamily M alpha, member 1 0.0488706
PSD3 pleckstrin and Sec7 domain containing 3 0.048433
ENO1 enolase 1, (alpha) 0.0468141
PRELID2 PRELI domain containing 2 0.0462142
COPA coatomer protein complex, subunit alpha 0.045881
DSPP dentin sialophosphoprotein 0.0455095
TPM3 tropomyosin 3 0.0454134
GPRC5A G protein-coupled receptor, class C, group 5, member A 0.0450177
ADAMTS16 ADAM metallopeptidase with thrombospondin type 1 motif, 16 0.0449612
FNIP1 folliculin interacting protein 1 0.0449323
MACF1 microtubule-actin crosslinking factor 1 0.0448604
PDLIM5 PDZ and LIM domain 5 0.0448176
ESYT2 extended synaptotagmin-like protein 2 0.0431365
SLC5A3 solute carrier family 5 (sodium/myo-inositol cotransporter), member 3 0.0430387
ABL2 ABL proto-oncogene 2, non-receptor tyrosine kinase 0.0424266
SUCO SUN domain containing ossification factor 0.0414801
CTNNA1 catenin (cadherin-associated protein), alpha 1, 102kDa 0.0399235
GRB10 growth factor receptor-bound protein 10 0.0395484
MBNL1 muscleblind-like splicing regulator 1 0.0394397
HSP90AB1 heat shock protein 90kDa alpha (cytosolic), class B member 1 0.0393122
CANX calnexin 0.038739
DST dystonin 0.038637
DPYD dihydropyrimidine dehydrogenase 0.0385458
COPB1 coatomer protein complex, subunit beta 1 0.0382252
CALR calreticulin 0.0372337
KLF5 Kruppel-like factor 5 (intestinal) 0.0362924
NPM1 nucleophosmin (nucleolar phosphoprotein B23, numatrin) 0.0360641
ITGA2 integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) 0.0357125
MXI1 MAX interactor 1, dimerization protein 0.0351381
GOLGB1 golgin B1 0.0351266
ARRDC3 arrestin domain containing 3 0.0351222
SQSTM1 sequestosome 1 0.0350279
DIS3 DIS3 exosome endoribonuclease and 3'-5' exoribonuclease 0.0350151
OGA O-GlcNAcase 0.0342819
APP amyloid beta (A4) precursor protein 0.0342054
AKAP13 A kinase (PRKA) anchor protein 13 0.0336842
RBM39 RNA binding motif protein 39 0.0330286
RND3 Rho family GTPase 3 0.0330186
HIVEP3 human immunodeficiency virus type I enhancer binding protein 3 0.0328226
PABPC1 poly(A) binding protein, cytoplasmic 1 0.0327702
ERRFI1 ERBB receptor feedback inhibitor 1 0.0327193
NRIP1 nuclear receptor interacting protein 1 0.0326297
SRRM1 serine/arginine repetitive matrix 1 0.0321884
CLU clusterin 0.0321696
IFIT2 interferon-induced protein with tetratricopeptide repeats 2 0.0321505
PTK2 protein tyrosine kinase 2 0.0316247
TSC22D1 TSC22 domain family, member 1 0.0315836
GFPT1 glutamine--fructose-6-phosphate transaminase 1 0.0315385
HERC4 HECT and RLD domain containing E3 ubiquitin protein ligase 4 0.0313174
HNRNPU heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) 0.0311138
AKAP9 A kinase (PRKA) anchor protein 9 0.0308068
ATP1B1 ATPase, Na+/K+ transporting, beta 1 polypeptide 0.0308028
PPFIBP1 PTPRF interacting protein, binding protein 1 (liprin beta 1) 0.0307688
MYH9 myosin, heavy chain 9, non-muscle 0.0301444
YWHAZ tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta 0.0299703
DOK5 docking protein 5 0.0298946
TTC3 tetratricopeptide repeat domain 3 0.0298814
ALCAM activated leukocyte cell adhesion molecule 0.029687
HMGA2 high mobility group AT-hook 2 0.0295499
ASAP2 ArfGAP with SH3 domain, ankyrin repeat and PH domain 2 0.0293942
ANO6 anoctamin 6 0.0293642
PPP1R15A protein phosphatase 1, regulatory subunit 15A 0.0292532
PJA2 praja ring finger 2, E3 ubiquitin protein ligase 0.0292424
KMT2C lysine (K)-specific methyltransferase 2C 0.0288689
ITCH itchy E3 ubiquitin protein ligase 0.0288225
PODXL podocalyxin-like 0.0287973
NAB1 NGFI-A binding protein 1 (EGR1 binding protein 1) 0.028484
COG5 component of oligomeric golgi complex 5 0.02835
LNPEP leucyl/cystinyl aminopeptidase 0.0283204
PTTG1IP pituitary tumor-transforming 1 interacting protein 0.0281677
STAU1 staufen double-stranded RNA binding protein 1 0.0281338
BZW1 basic leucine zipper and W2 domains 1 0.028064
RICTOR RPTOR independent companion of MTOR, complex 2 0.0280349
ASAP1 ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 0.028015
HUWE1 HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase 0.0279465
QKI QKI, KH domain containing, RNA binding 0.0278893
CLIC4 chloride intracellular channel 4 0.027677
SERINC3 serine incorporator 3 0.0271334
CALU calumenin 0.0271242

decreased expression

Symbol Name Standardized Value
GAPDH glyceraldehyde-3-phosphate dehydrogenase -0.171699
RPS21 ribosomal protein S21 -0.128041
MT2A metallothionein 2A -0.102169
TMSB10 thymosin beta 10 -0.100863
POTEF POTE ankyrin domain family, member F -0.0898721
TIMP3 TIMP metallopeptidase inhibitor 3 -0.0763954
PPDPF pancreatic progenitor cell differentiation and proliferation factor -0.0732989
RPLP1 ribosomal protein, large, P1 -0.0664289
RPS6 ribosomal protein S6 -0.0653465
RPLP2 ribosomal protein, large, P2 -0.062127
RPL11 ribosomal protein L11 -0.0594683
LOC112694756 uncharaterized LOC112694756 -0.0594353
S100A9 S100 calcium binding protein A9 -0.0585456
IFITM3 interferon induced transmembrane protein 3 -0.0568343
TPT1 tumor protein, translationally-controlled 1 -0.0542933
RPS13 ribosomal protein S13 -0.0542647
RPS8 ribosomal protein S8 -0.0528157
CYB5R3 cytochrome b5 reductase 3 -0.0516473
RPS14 ribosomal protein S14 -0.0509708
FOSL1 FOS-like antigen 1 -0.0501706
PTMA prothymosin, alpha -0.0494725
FOXO1 forkhead box O1 -0.0482118
RPS19 ribosomal protein S19 -0.0478551
KCNK1 potassium channel, two pore domain subfamily K, member 1 -0.0464207
PSMA7 proteasome (prosome, macropain) subunit, alpha type, 7 -0.0455778
S100A6 S100 calcium binding protein A6 -0.044319
SH3BGRL3 SH3 domain binding glutamate-rich protein like 3 -0.0438341
YWHAB tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta -0.0436741
IFITM1 interferon induced transmembrane protein 1 -0.0432828
IFI27 interferon, alpha-inducible protein 27 -0.0429694
RPL35A ribosomal protein L35a -0.0426263
HLA-B major histocompatibility complex, class I, B -0.0425202
FTL ferritin, light polypeptide -0.0422775
RPL31 ribosomal protein L31 -0.0421814
RPL9 ribosomal protein L9 -0.0400548
S100A2 S100 calcium binding protein A2 -0.0397153
RPL37 ribosomal protein L37 -0.0395357
BCL2L1 BCL2-like 1 -0.0381471
RPL34 ribosomal protein L34 -0.0380119
MT1X metallothionein 1X -0.0378895
RPLP0 ribosomal protein, large, P0 -0.0363051
RPL27A ribosomal protein L27a -0.0362319
HSP90AA1 heat shock protein 90kDa alpha (cytosolic), class A member 1 -0.0361065
RPS23 ribosomal protein S23 -0.0359271
CNRIP1 cannabinoid receptor interacting protein 1 -0.0358622
RPL36 ribosomal protein L36 -0.0343791
ATP5F1B ATP synthase F1 subunit beta -0.0343199
CDKN2A cyclin-dependent kinase inhibitor 2A -0.0333018
SULF1 sulfatase 1 -0.0332241
RPL19 ribosomal protein L19 -0.032413
MDK midkine (neurite growth-promoting factor 2) -0.031928
RPL35 ribosomal protein L35 -0.0315378
IFI6 interferon, alpha-inducible protein 6 -0.0300547
FTH1 ferritin, heavy polypeptide 1 -0.0298211
PFN1 profilin 1 -0.0298124
RPS5 ribosomal protein S5 -0.0296919
S100A11 S100 calcium binding protein A11 -0.0296059
RPL23 ribosomal protein L23 -0.0295869
ACTN4 actinin, alpha 4 -0.0295343
ITGA3 integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor) -0.0295304
RPL36A ribosomal protein L36a -0.0286902
RPL8 ribosomal protein L8 -0.0282517
RPS20 ribosomal protein S20 -0.0281802
RPS27 ribosomal protein S27 -0.0279875
COX4I1 cytochrome c oxidase subunit IV isoform 1 -0.0278605
EFHD2 EF-hand domain family, member D2 -0.0276677
GUK1 guanylate kinase 1 -0.0275881
RPS15 ribosomal protein S15 -0.0275636
KRT19 keratin 19, type I -0.0274882
TAGLN2 transgelin 2 -0.0273831
RPS4X ribosomal protein S4, X-linked -0.0272728
RPL39 ribosomal protein L39 -0.0268148
RPL12 ribosomal protein L12 -0.0267178
ZMYND8 zinc finger, MYND-type containing 8 -0.0261386
S100A10 S100 calcium binding protein A10 -0.025601
RPL32 ribosomal protein L32 -0.0255015
YBX1 Y box binding protein 1 -0.0253636
DDAH1 dimethylarginine dimethylaminohydrolase 1 -0.0252451
HSD17B2 hydroxysteroid (17-beta) dehydrogenase 2 -0.0250773
ASTN2 astrotactin 2 -0.0248639
RPL30 ribosomal protein L30 -0.0245759
WSB1 WD repeat and SOCS box containing 1 -0.0242706
RPS25 ribosomal protein S25 -0.0238958
ISG15 ISG15 ubiquitin-like modifier -0.0236862
LAMA5 laminin, alpha 5 -0.023661
UQCRB ubiquinol-cytochrome c reductase binding protein -0.0235329
RPL37A ribosomal protein L37a -0.0234854
LMNA lamin A/C -0.0232555
PKM pyruvate kinase, muscle -0.0230751
RPL28 ribosomal protein L28 -0.0228761
TINAGL1 tubulointerstitial nephritis antigen-like 1 -0.0228728
IGFBP4 insulin-like growth factor binding protein 4 -0.022797
ADRM1 adhesion regulating molecule 1 -0.0227128
HMGA1 high mobility group AT-hook 1 -0.0225782
RPS24 ribosomal protein S24 -0.0224631
ARHGAP29 Rho GTPase activating protein 29 -0.0222763
ARPC1B actin related protein 2/3 complex, subunit 1B, 41kDa -0.0220002
CD59 CD59 molecule, complement regulatory protein -0.0219909
OSMR oncostatin M receptor -0.0217152
LUZP1 leucine zipper protein 1 -0.0215526