γ-Oryzanol_LS 180 Gene Set

Dataset Tahoe Therapeutics Tahoe 100M Perturbation Atlas
Category transcriptomics
Type cell type
Description γ-Oryzanol perturbation in LS 180 cell line (Tahoe Therapeutics)
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Genes

200 genes differentially expressed following the γ-Oryzanol_LS 180 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.

increased expression

Symbol Name Standardized Value
PABPC1 poly(A) binding protein, cytoplasmic 1 0.0895531
LMO7 LIM domain 7 0.0891498
DSPP dentin sialophosphoprotein 0.0883011
ITGA6 integrin, alpha 6 0.0848327
EZR ezrin 0.0819464
FAT1 FAT atypical cadherin 1 0.0809556
SLC12A2 solute carrier family 12 (sodium/potassium/chloride transporter), member 2 0.0807221
SPTBN1 spectrin, beta, non-erythrocytic 1 0.0795843
HSP90AB1 heat shock protein 90kDa alpha (cytosolic), class B member 1 0.0737323
KRT8 keratin 8, type II 0.0696327
P4HA1 prolyl 4-hydroxylase, alpha polypeptide I 0.0638268
TXNIP thioredoxin interacting protein 0.0617881
HSP90B1 heat shock protein 90kDa beta (Grp94), member 1 0.0598611
EEF2 eukaryotic translation elongation factor 2 0.0567332
LDHA lactate dehydrogenase A 0.0558395
ANXA1 annexin A1 0.053322
KRT18 keratin 18, type I 0.0507588
MUC6 mucin 6, oligomeric mucus/gel-forming 0.0507154
FAM13A family with sequence similarity 13, member A 0.0461548
FOS FBJ murine osteosarcoma viral oncogene homolog 0.0460362
VEGFA vascular endothelial growth factor A 0.0389268
EMP1 epithelial membrane protein 1 0.038762
TNFRSF21 tumor necrosis factor receptor superfamily, member 21 0.0381922
AFF1 AF4/FMR2 family, member 1 0.0344593
ZNF292 zinc finger protein 292 0.0332698
EPS8 epidermal growth factor receptor pathway substrate 8 0.0328459
ERRFI1 ERBB receptor feedback inhibitor 1 0.0326387
ENO1 enolase 1, (alpha) 0.031943
TTC3 tetratricopeptide repeat domain 3 0.031689
CEMIP cell migration inducing protein, hyaluronan binding 0.0310435
MBNL2 muscleblind-like splicing regulator 2 0.0300697
ASPH aspartate beta-hydroxylase 0.0298701
MBNL1 muscleblind-like splicing regulator 1 0.0292005
ARHGAP12 Rho GTPase activating protein 12 0.0286697
CLCN3 chloride channel, voltage-sensitive 3 0.028113
NFAT5 nuclear factor of activated T-cells 5, tonicity-responsive 0.0277667
PPP2R2A protein phosphatase 2, regulatory subunit B, alpha 0.0277094
GAREM1 GRB2 associated regulator of MAPK1 subtype 1 0.0276528
MED13 mediator complex subunit 13 0.0275911
NCOR1 nuclear receptor corepressor 1 0.0270482
ITPRID2 ITPR interacting domain containing 2 0.0268538
EREG epiregulin 0.026773
MXI1 MAX interactor 1, dimerization protein 0.0266002
TPM3 tropomyosin 3 0.0262989
ARIH1 ariadne RBR E3 ubiquitin protein ligase 1 0.0262347
PIGR polymeric immunoglobulin receptor 0.0261519
CCNY cyclin Y 0.0260819
MLEC malectin 0.0260394
LGR4 leucine-rich repeat containing G protein-coupled receptor 4 0.0258058
AKAP13 A kinase (PRKA) anchor protein 13 0.0253293
GFPT1 glutamine--fructose-6-phosphate transaminase 1 0.0250672
LOC102724023 ES1 protein homolog, mitochondrial 0.0249198
PCBP2 poly(rC) binding protein 2 0.0248912
FHIP1A FHF complex subunit HOOK interacting protein 1A 0.0248376
SHROOM3 shroom family member 3 0.0247682
PDIA3 protein disulfide isomerase family A, member 3 0.0244336
UBA6 ubiquitin-like modifier activating enzyme 6 0.024267
KMT2E lysine (K)-specific methyltransferase 2E 0.0241383
BIRC6 baculoviral IAP repeat containing 6 0.0240327
TPD52 tumor protein D52 0.0238273
NEDD9 neural precursor cell expressed, developmentally down-regulated 9 0.0235762
DDIT4 DNA-damage-inducible transcript 4 0.023442
MED13L mediator complex subunit 13-like 0.0233678
CALR calreticulin 0.0232647
NDRG1 N-myc downstream regulated 1 0.0232375
SRRM1 serine/arginine repetitive matrix 1 0.0231804
PGK1 phosphoglycerate kinase 1 0.0229846
HSPD1 heat shock 60kDa protein 1 (chaperonin) 0.0225375
FNDC3B fibronectin type III domain containing 3B 0.022518
RBPJ recombination signal binding protein for immunoglobulin kappa J region 0.0223771
SPAG9 sperm associated antigen 9 0.0223689
EHF ets homologous factor 0.0223608
COPA coatomer protein complex, subunit alpha 0.0222911
CNOT1 CCR4-NOT transcription complex, subunit 1 0.0222523
SBF2 SET binding factor 2 0.0218595
PCM1 pericentriolar material 1 0.0218509
PPARG peroxisome proliferator-activated receptor gamma 0.0217328
SERINC5 serine incorporator 5 0.0216974
GREB1L growth regulation by estrogen in breast cancer-like 0.0215683
ARHGAP5 Rho GTPase activating protein 5 0.0214742
ERBIN erbb2 interacting protein 0.0213729
ESYT2 extended synaptotagmin-like protein 2 0.0212336
RHPN2 rhophilin, Rho GTPase binding protein 2 0.0211661
SCARB2 scavenger receptor class B, member 2 0.0210839
EIF3A eukaryotic translation initiation factor 3, subunit A 0.0209191
FLNB filamin B, beta 0.0208937
BNIP3L BCL2/adenovirus E1B 19kDa interacting protein 3-like 0.0208032
NPM1 nucleophosmin (nucleolar phosphoprotein B23, numatrin) 0.020747
ANKRD17 ankyrin repeat domain 17 0.0204284
KIF5B kinesin family member 5B 0.0203577
SEC31A SEC31 homolog A (S. cerevisiae) 0.0203221
DSCAM Down syndrome cell adhesion molecule 0.020206
DSG2 desmoglein 2 0.0197037
ANXA2 annexin A2 0.0193581
PELI1 pellino E3 ubiquitin protein ligase 1 0.0192242
GLS2 glutaminase 2 (liver, mitochondrial) 0.0191715
USP6NL USP6 N-terminal like 0.0191532
PTPRR protein tyrosine phosphatase, receptor type, R 0.01912
PATJ PATJ crumbs cell polarity complex component 0.0190063
AFDN afadin, adherens junction formation factor 0.0189365

decreased expression

Symbol Name Standardized Value
TMSB10 thymosin beta 10 -0.123135
TPT1 tumor protein, translationally-controlled 1 -0.121054
PTMA prothymosin, alpha -0.113494
RPS6 ribosomal protein S6 -0.0941278
RPL35A ribosomal protein L35a -0.0860271
RPLP1 ribosomal protein, large, P1 -0.0777957
RPL34 ribosomal protein L34 -0.0584513
RPLP2 ribosomal protein, large, P2 -0.0541001
RPL9 ribosomal protein L9 -0.0521681
RPS8 ribosomal protein S8 -0.0519482
RPL23 ribosomal protein L23 -0.0477307
RPS19 ribosomal protein S19 -0.0450634
RPS24 ribosomal protein S24 -0.0444051
ONECUT3 one cut homeobox 3 -0.0435054
RPL36 ribosomal protein L36 -0.0416807
RPL31 ribosomal protein L31 -0.040626
RPS29 ribosomal protein S29 -0.0398213
RPL37A ribosomal protein L37a -0.039135
RPS27A ribosomal protein S27a -0.0378454
RPL26 ribosomal protein L26 -0.0377431
RPS21 ribosomal protein S21 -0.0363388
IER3 immediate early response 3 -0.0342068
RPS23 ribosomal protein S23 -0.0338112
RPL12 ribosomal protein L12 -0.0337813
ACTG1 actin gamma 1 -0.0323482
RPS13 ribosomal protein S13 -0.0315176
GAPDH glyceraldehyde-3-phosphate dehydrogenase -0.0315159
UQCRB ubiquinol-cytochrome c reductase binding protein -0.0314943
HSP90AA1 heat shock protein 90kDa alpha (cytosolic), class A member 1 -0.0299939
MT2A metallothionein 2A -0.0297545
FTL ferritin, light polypeptide -0.0294604
RPL37 ribosomal protein L37 -0.0293612
RPS25 ribosomal protein S25 -0.0288235
RPL19 ribosomal protein L19 -0.0273174
RPL38 ribosomal protein L38 -0.0268449
RPS14 ribosomal protein S14 -0.0267926
RPL11 ribosomal protein L11 -0.0266582
RPS27 ribosomal protein S27 -0.0266233
RPL17-C18ORF32 RPL17-C18orf32 readthrough -0.0266144
RPS12 ribosomal protein S12 -0.0264225
S100P S100 calcium binding protein P -0.0248369
RPL27 ribosomal protein L27 -0.0245405
RPL36A ribosomal protein L36a -0.0238207
CD55 CD55 molecule, decay accelerating factor for complement (Cromer blood group) -0.0234757
RPL27A ribosomal protein L27a -0.0226409
S100A6 S100 calcium binding protein A6 -0.0225804
RPL30 ribosomal protein L30 -0.0224326
RPL28 ribosomal protein L28 -0.0219296
RPL7A ribosomal protein L7a -0.0215275
TNS4 tensin 4 -0.0214085
RPS11 ribosomal protein S11 -0.0212857
VCL vinculin -0.0199452
RPS20 ribosomal protein S20 -0.0197702
RPS17 ribosomal protein S17 -0.0196049
RPL36AL ribosomal protein L36a-like -0.0193396
RPS16 ribosomal protein S16 -0.0184291
RPL13A ribosomal protein L13a -0.0184196
HNRNPH1 heterogeneous nuclear ribonucleoprotein H1 (H) -0.0182428
RPL5 ribosomal protein L5 -0.0181014
VDR vitamin D (1,25- dihydroxyvitamin D3) receptor -0.0175974
TUBB4B tubulin, beta 4B class IVb -0.0174416
RPS10 ribosomal protein S10 -0.017152
RPL35 ribosomal protein L35 -0.0170684
HMGB1 high mobility group box 1 -0.016549
UQCRQ ubiquinol-cytochrome c reductase, complex III subunit VII, 9.5kDa -0.0159882
RPL32 ribosomal protein L32 -0.015875
YWHAB tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta -0.0157665
RPS15 ribosomal protein S15 -0.0149967
COX5A cytochrome c oxidase subunit Va -0.014995
ATP5F1B ATP synthase F1 subunit beta -0.0149357
CALM1 calmodulin 1 (phosphorylase kinase, delta) -0.0146942
PRSS3 protease, serine, 3 -0.0146536
RPL8 ribosomal protein L8 -0.0145411
COX4I1 cytochrome c oxidase subunit IV isoform 1 -0.0141856
NDUFA4 NDUFA4, mitochondrial complex associated -0.0141817
IMMP2L IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) -0.0140861
EIF5B eukaryotic translation initiation factor 5B -0.0140729
NT5C2 5'-nucleotidase, cytosolic II -0.0137498
RRBP1 ribosome binding protein 1 -0.0136474
COX6C cytochrome c oxidase subunit VIc -0.0135321
PNISR PNN-interacting serine/arginine-rich protein -0.0133498
TFF1 trefoil factor 1 -0.0133327
IRF2BP2 interferon regulatory factor 2 binding protein 2 -0.0132232
EEF1D eukaryotic translation elongation factor 1 delta (guanine nucleotide exchange protein) -0.0132158
EEF1B2 eukaryotic translation elongation factor 1 beta 2 -0.0130587
HNRNPK heterogeneous nuclear ribonucleoprotein K -0.01296
FDPS farnesyl diphosphate synthase -0.0126604
S100A9 S100 calcium binding protein A9 -0.0126232
SELENOK selenoprotein K -0.0124717
RPLP0 ribosomal protein, large, P0 -0.012417
RPS5 ribosomal protein S5 -0.0123808
SLC25A3 solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 3 -0.0120404
PSMA7 proteasome (prosome, macropain) subunit, alpha type, 7 -0.0119383
UBA52 ubiquitin A-52 residue ribosomal protein fusion product 1 -0.0118324
RNF43 ring finger protein 43 -0.0117719
RPL15 ribosomal protein L15 -0.0117093
ISG15 ISG15 ubiquitin-like modifier -0.0114634
RPS4X ribosomal protein S4, X-linked -0.0114264
MYL12B myosin, light chain 12B, regulatory -0.011354
ANKRD10 ankyrin repeat domain 10 -0.0112401