| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | γ-Oryzanol perturbation in MIA PaCa-2 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the γ-Oryzanol_MIA PaCa-2 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.149249 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | 0.120877 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | 0.101533 |
| POTEF | POTE ankyrin domain family, member F | 0.0998853 |
| DST | dystonin | 0.0935902 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0895805 |
| KTN1 | kinectin 1 (kinesin receptor) | 0.0860431 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.08336 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | 0.0700373 |
| ZDHHC14 | zinc finger, DHHC-type containing 14 | 0.0687787 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | 0.0679114 |
| TP63 | tumor protein p63 | 0.0655824 |
| PLK2 | polo-like kinase 2 | 0.0628247 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | 0.0616721 |
| FMNL2 | formin-like 2 | 0.0613896 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | 0.0610574 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | 0.0590786 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0582721 |
| SERPINA3 | serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 3 | 0.0569915 |
| ENO1 | enolase 1, (alpha) | 0.0563609 |
| EIF2AK2 | eukaryotic translation initiation factor 2-alpha kinase 2 | 0.053651 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0514979 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | 0.0511409 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.0488965 |
| EHBP1 | EH domain binding protein 1 | 0.0485689 |
| PLEKHA4 | pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 4 | 0.0478099 |
| CAPRIN2 | caprin family member 2 | 0.0477541 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | 0.0465688 |
| RUNX1 | runt-related transcription factor 1 | 0.0464785 |
| SET | SET nuclear proto-oncogene | 0.0452477 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | 0.0435809 |
| VMP1 | vacuole membrane protein 1 | 0.0432271 |
| ANGPTL4 | angiopoietin-like 4 | 0.0431625 |
| DPYD | dihydropyrimidine dehydrogenase | 0.042132 |
| CCNL1 | cyclin L1 | 0.0414376 |
| ENO2 | enolase 2 (gamma, neuronal) | 0.0412378 |
| USP34 | ubiquitin specific peptidase 34 | 0.0410421 |
| B2M | beta-2-microglobulin | 0.0408899 |
| MKI67 | marker of proliferation Ki-67 | 0.0407691 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0404247 |
| RAD51B | RAD51 paralog B | 0.0399394 |
| EIF4G1 | eukaryotic translation initiation factor 4 gamma, 1 | 0.0398402 |
| TXNIP | thioredoxin interacting protein | 0.038286 |
| LDHA | lactate dehydrogenase A | 0.0377421 |
| BPTF | bromodomain PHD finger transcription factor | 0.0375994 |
| CENPF | centromere protein F, 350/400kDa | 0.0373276 |
| HDAC9 | histone deacetylase 9 | 0.0371517 |
| TSC22D1 | TSC22 domain family, member 1 | 0.0363457 |
| TANC2 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 | 0.0362482 |
| EPHA4 | EPH receptor A4 | 0.0359553 |
| TPM3 | tropomyosin 3 | 0.0343343 |
| ZNF638 | zinc finger protein 638 | 0.0340842 |
| MBNL2 | muscleblind-like splicing regulator 2 | 0.034031 |
| HSPA9 | heat shock 70kDa protein 9 (mortalin) | 0.0339865 |
| TPR | translocated promoter region, nuclear basket protein | 0.0335783 |
| CADM2 | cell adhesion molecule 2 | 0.033577 |
| PRRC2C | proline-rich coiled-coil 2C | 0.0331885 |
| APP | amyloid beta (A4) precursor protein | 0.0327486 |
| PCBP2 | poly(rC) binding protein 2 | 0.032254 |
| SRGAP1 | SLIT-ROBO Rho GTPase activating protein 1 | 0.0321034 |
| RNF213 | ring finger protein 213 | 0.0319981 |
| CDK19 | cyclin-dependent kinase 19 | 0.0318625 |
| MYADM | myeloid-associated differentiation marker | 0.0318143 |
| JMJD1C | jumonji domain containing 1C | 0.0308295 |
| EREG | epiregulin | 0.0308207 |
| TIMP2 | TIMP metallopeptidase inhibitor 2 | 0.0306598 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0306017 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | 0.030336 |
| RERE | arginine-glutamic acid dipeptide (RE) repeats | 0.0301902 |
| KMT2E | lysine (K)-specific methyltransferase 2E | 0.0300595 |
| OSBPL8 | oxysterol binding protein-like 8 | 0.0297116 |
| VEGFA | vascular endothelial growth factor A | 0.0296811 |
| PKM | pyruvate kinase, muscle | 0.0294864 |
| MBD5 | methyl-CpG binding domain protein 5 | 0.0291903 |
| ANKIB1 | ankyrin repeat and IBR domain containing 1 | 0.0291637 |
| SRSF11 | serine/arginine-rich splicing factor 11 | 0.0291623 |
| ATP2B4 | ATPase, Ca++ transporting, plasma membrane 4 | 0.0290443 |
| SYNE2 | spectrin repeat containing, nuclear envelope 2 | 0.0290295 |
| PTPRF | protein tyrosine phosphatase, receptor type, F | 0.0290097 |
| SEMA3C | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C | 0.0288817 |
| BRD2 | bromodomain containing 2 | 0.0288515 |
| SLK | STE20-like kinase | 0.028814 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | 0.0286268 |
| GCLM | glutamate-cysteine ligase, modifier subunit | 0.0286236 |
| PRKRIP1 | PRKR interacting protein 1 (IL11 inducible) | 0.0286118 |
| XPO1 | exportin 1 | 0.0285904 |
| SLC38A2 | solute carrier family 38, member 2 | 0.0284332 |
| TBC1D5 | TBC1 domain family, member 5 | 0.0281841 |
| IL1RAPL1 | interleukin 1 receptor accessory protein-like 1 | 0.0280706 |
| PCM1 | pericentriolar material 1 | 0.0277835 |
| MBNL1 | muscleblind-like splicing regulator 1 | 0.027696 |
| ERC1 | ELKS/RAB6-interacting/CAST family member 1 | 0.027677 |
| MINDY2 | MINDY lysine 48 deubiquitinase 2 | 0.0276619 |
| IGF2BP3 | insulin-like growth factor 2 mRNA binding protein 3 | 0.0274435 |
| TNS3 | tensin 3 | 0.0273024 |
| BRD4 | bromodomain containing 4 | 0.0269754 |
| LPP | LIM domain containing preferred translocation partner in lipoma | 0.0267529 |
| EGR1 | early growth response 1 | 0.0265953 |
| DNER | delta/notch-like EGF repeat containing | 0.0263852 |
| CSNK1A1 | casein kinase 1, alpha 1 | 0.0263767 |
| Symbol | Name | Standardized Value |
|---|---|---|
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.284277 |
| TMSB10 | thymosin beta 10 | -0.135333 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0825112 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0771613 |
| AHNAK | AHNAK nucleoprotein | -0.0719296 |
| RPL35A | ribosomal protein L35a | -0.0703077 |
| RPL12 | ribosomal protein L12 | -0.0446212 |
| RPLP1 | ribosomal protein, large, P1 | -0.0428566 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0423301 |
| KDM3A | lysine (K)-specific demethylase 3A | -0.041571 |
| RPS8 | ribosomal protein S8 | -0.0400401 |
| RPL26 | ribosomal protein L26 | -0.0382013 |
| RPS24 | ribosomal protein S24 | -0.0380929 |
| RTN4 | reticulon 4 | -0.0371486 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0371363 |
| PYGB | phosphorylase, glycogen; brain | -0.0354418 |
| GPAT3 | glycerol-3-phosphate acyltransferase 3 | -0.0347372 |
| HDLBP | high density lipoprotein binding protein | -0.03329 |
| RPL23 | ribosomal protein L23 | -0.0328907 |
| RPL34 | ribosomal protein L34 | -0.0328717 |
| GNB1 | guanine nucleotide binding protein (G protein), beta polypeptide 1 | -0.0327478 |
| WARS1 | tryptophanyl-tRNA synthetase 1 | -0.0324909 |
| SLC4A7 | solute carrier family 4, sodium bicarbonate cotransporter, member 7 | -0.0311529 |
| GNAS | GNAS complex locus | -0.0307942 |
| TMEM41B | transmembrane protein 41B | -0.0295537 |
| RPS27A | ribosomal protein S27a | -0.0294495 |
| GCNT2 | glucosaminyl (N-acetyl) transferase 2, I-branching enzyme (I blood group) | -0.0277852 |
| MARCHF6 | membrane associated ring-CH-type finger 6 | -0.0270694 |
| RPL6 | ribosomal protein L6 | -0.0270601 |
| ARF1 | ADP-ribosylation factor 1 | -0.0269421 |
| RPLP0 | ribosomal protein, large, P0 | -0.0268813 |
| BZW1 | basic leucine zipper and W2 domains 1 | -0.0266205 |
| DDX5 | DEAD (Asp-Glu-Ala-Asp) box helicase 5 | -0.0257291 |
| RPL4 | ribosomal protein L4 | -0.0253633 |
| RPS4X | ribosomal protein S4, X-linked | -0.0253517 |
| YBX1 | Y box binding protein 1 | -0.0251557 |
| RPL11 | ribosomal protein L11 | -0.0237125 |
| B4GALT5 | UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 5 | -0.0235435 |
| SMURF1 | SMAD specific E3 ubiquitin protein ligase 1 | -0.023367 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.0231646 |
| TMSB4X | thymosin beta 4, X-linked | -0.0231594 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | -0.02308 |
| SRGN | serglycin | -0.0228657 |
| OLA1 | Obg-like ATPase 1 | -0.022853 |
| RPL9 | ribosomal protein L9 | -0.0227828 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0225651 |
| IFNGR2 | interferon gamma receptor 2 (interferon gamma transducer 1) | -0.0218182 |
| RAB1A | RAB1A, member RAS oncogene family | -0.021748 |
| RPL38 | ribosomal protein L38 | -0.0217466 |
| CFDP1 | craniofacial development protein 1 | -0.0215878 |
| GOLT1B | golgi transport 1B | -0.0214864 |
| PDIA5 | protein disulfide isomerase family A, member 5 | -0.0213459 |
| EMP1 | epithelial membrane protein 1 | -0.0211329 |
| TMEM263 | transmembrane protein 263 | -0.0210813 |
| CANX | calnexin | -0.0210747 |
| RPS6 | ribosomal protein S6 | -0.0207098 |
| RHEB | Ras homolog enriched in brain | -0.0205291 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | -0.0203682 |
| ARPC2 | actin related protein 2/3 complex, subunit 2, 34kDa | -0.0203333 |
| PPP2CA | protein phosphatase 2, catalytic subunit, alpha isozyme | -0.0202014 |
| HNRNPK | heterogeneous nuclear ribonucleoprotein K | -0.0201015 |
| TNFRSF10B | tumor necrosis factor receptor superfamily, member 10b | -0.0199927 |
| RPS23 | ribosomal protein S23 | -0.019898 |
| PTMA | prothymosin, alpha | -0.0195798 |
| ZNF267 | zinc finger protein 267 | -0.0195721 |
| SEPTIN2 | septin 2 | -0.0193303 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | -0.0192745 |
| RRBP1 | ribosome binding protein 1 | -0.0191358 |
| POLR2A | polymerase (RNA) II (DNA directed) polypeptide A, 220kDa | -0.0190943 |
| AGO2 | argonaute RISC catalytic component 2 | -0.0190496 |
| RPS20 | ribosomal protein S20 | -0.0189218 |
| HMGB2 | high mobility group box 2 | -0.0187514 |
| SLC38A1 | solute carrier family 38, member 1 | -0.0186641 |
| MAPK8 | mitogen-activated protein kinase 8 | -0.0184726 |
| RPL19 | ribosomal protein L19 | -0.0184386 |
| RPL30 | ribosomal protein L30 | -0.0184313 |
| NFE2L2 | nuclear factor, erythroid 2-like 2 | -0.0184274 |
| KPNA4 | karyopherin alpha 4 (importin alpha 3) | -0.0184204 |
| MECP2 | methyl CpG binding protein 2 | -0.0182888 |
| OGA | O-GlcNAcase | -0.0182127 |
| RPL17-C18ORF32 | RPL17-C18orf32 readthrough | -0.0182022 |
| SPRY4 | sprouty homolog 4 (Drosophila) | -0.0179578 |
| SENP5 | SUMO1/sentrin specific peptidase 5 | -0.0179144 |
| ETNK1 | ethanolamine kinase 1 | -0.0176988 |
| ZNF644 | zinc finger protein 644 | -0.0176263 |
| AP3B1 | adaptor-related protein complex 3, beta 1 subunit | -0.0176164 |
| RPS28 | ribosomal protein S28 | -0.0175886 |
| RPL37 | ribosomal protein L37 | -0.0175489 |
| CALU | calumenin | -0.0174736 |
| UBE2E3 | ubiquitin-conjugating enzyme E2E 3 | -0.0174734 |
| ELOVL5 | ELOVL fatty acid elongase 5 | -0.0174637 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0174529 |
| FBXO34 | F-box protein 34 | -0.0173177 |
| RPS6KA3 | ribosomal protein S6 kinase, 90kDa, polypeptide 3 | -0.017202 |
| ARFGEF2 | ADP-ribosylation factor guanine nucleotide-exchange factor 2 (brefeldin A-inhibited) | -0.017146 |
| NPR2 | natriuretic peptide receptor 2 | -0.017122 |
| EEF1B2 | eukaryotic translation elongation factor 1 beta 2 | -0.0169604 |
| ZFAND3 | zinc finger, AN1-type domain 3 | -0.0167512 |
| SEC61A1 | Sec61 alpha 1 subunit (S. cerevisiae) | -0.0166522 |
| RRAS2 | related RAS viral (r-ras) oncogene homolog 2 | -0.0165943 |