γ-Oryzanol_SW 900 Gene Set

Dataset Tahoe Therapeutics Tahoe 100M Perturbation Atlas
Category transcriptomics
Type cell type
Description γ-Oryzanol perturbation in SW 900 cell line (Tahoe Therapeutics)
Similar Terms
Downloads & Tools

Genes

200 genes differentially expressed following the γ-Oryzanol_SW 900 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.

increased expression

Symbol Name Standardized Value
NAMPT nicotinamide phosphoribosyltransferase 0.247722
PLOD2 procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 0.103343
P4HA1 prolyl 4-hydroxylase, alpha polypeptide I 0.097165
ITGA2 integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) 0.0842438
TXNIP thioredoxin interacting protein 0.0813306
CYP1B1 cytochrome P450, family 1, subfamily B, polypeptide 1 0.0712957
TPR translocated promoter region, nuclear basket protein 0.0702402
CANX calnexin 0.0681321
PRRC2C proline-rich coiled-coil 2C 0.0646097
TMEM156 transmembrane protein 156 0.0633108
RBPJ recombination signal binding protein for immunoglobulin kappa J region 0.0624376
GBE1 glucan (1,4-alpha-), branching enzyme 1 0.0582432
PABPC1 poly(A) binding protein, cytoplasmic 1 0.0562256
SMYD3 SET and MYND domain containing 3 0.0493509
FAM13A family with sequence similarity 13, member A 0.0486928
TXNRD1 thioredoxin reductase 1 0.043987
ACBD3 acyl-CoA binding domain containing 3 0.0439333
VEGFA vascular endothelial growth factor A 0.043086
CLTC clathrin, heavy chain (Hc) 0.0422577
CD109 CD109 molecule 0.0417591
BASP1 brain abundant, membrane attached signal protein 1 0.0389981
MBD5 methyl-CpG binding domain protein 5 0.0376499
B2M beta-2-microglobulin 0.0376211
TRIO trio Rho guanine nucleotide exchange factor 0.0361081
FNDC3B fibronectin type III domain containing 3B 0.0354488
XPO1 exportin 1 0.0344339
ARRDC3 arrestin domain containing 3 0.0340457
LIFR leukemia inhibitory factor receptor alpha 0.0339852
YME1L1 YME1-like 1 ATPase 0.0332228
AP3B1 adaptor-related protein complex 3, beta 1 subunit 0.0327961
OGA O-GlcNAcase 0.0326206
CDCP1 CUB domain containing protein 1 0.0321594
FNBP1 formin binding protein 1 0.0314922
ITPR2 inositol 1,4,5-trisphosphate receptor, type 2 0.0313888
PGK1 phosphoglycerate kinase 1 0.0313456
TOR1AIP2 torsin A interacting protein 2 0.031052
SQSTM1 sequestosome 1 0.0306546
KDM3A lysine (K)-specific demethylase 3A 0.0306251
TM9SF3 transmembrane 9 superfamily member 3 0.0300773
DSG2 desmoglein 2 0.0300715
TMSB4X thymosin beta 4, X-linked 0.0296858
UGCG UDP-glucose ceramide glucosyltransferase 0.0295872
PJA2 praja ring finger 2, E3 ubiquitin protein ligase 0.0286809
CEP350 centrosomal protein 350kDa 0.0285874
IBTK inhibitor of Bruton agammaglobulinemia tyrosine kinase 0.0282639
HSP90AB1 heat shock protein 90kDa alpha (cytosolic), class B member 1 0.0276335
SKAP2 src kinase associated phosphoprotein 2 0.0272078
ODR4 odr-4 GPCR localization factor homolog 0.0271929
AFDN afadin, adherens junction formation factor 0.0271662
DHRS3 dehydrogenase/reductase (SDR family) member 3 0.027117
NUCKS1 nuclear casein kinase and cyclin-dependent kinase substrate 1 0.0271141
CALU calumenin 0.0269805
EREG epiregulin 0.0266264
ITGA1 integrin, alpha 1 0.026368
IGFBP3 insulin-like growth factor binding protein 3 0.0262711
STC2 stanniocalcin 2 0.0262291
SFTPA2 surfactant protein A2 0.0257704
DARS1 aspartyl-tRNA synthetase 1 0.025564
TMED2 transmembrane emp24 domain trafficking protein 2 0.025386
FBXO32 F-box protein 32 0.0253359
ACTR2 ARP2 actin-related protein 2 homolog (yeast) 0.0252751
TENT2 terminal nucleotidyltransferase 2 0.0250274
BCLAF1 BCL2-associated transcription factor 1 0.0248579
CEP95 centrosomal protein 95kDa 0.0244406
EGLN1 egl-9 family hypoxia-inducible factor 1 0.0243905
PTGS2 prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) 0.0243244
MNAT1 MNAT CDK-activating kinase assembly factor 1 0.0242672
SECISBP2L SECIS binding protein 2-like 0.0242473
SLC2A3 solute carrier family 2 (facilitated glucose transporter), member 3 0.0241629
APP amyloid beta (A4) precursor protein 0.0238556
DYNC1H1 dynein, cytoplasmic 1, heavy chain 1 0.0238208
PRELID2 PRELI domain containing 2 0.0238095
AKAP12 A kinase (PRKA) anchor protein 12 0.0237672
EYA1 EYA transcriptional coactivator and phosphatase 1 0.0236409
KMT2E lysine (K)-specific methyltransferase 2E 0.023572
BNIP3L BCL2/adenovirus E1B 19kDa interacting protein 3-like 0.0235369
DENND4C DENN/MADD domain containing 4C 0.0233329
TMF1 TATA element modulatory factor 1 0.0231111
RBM39 RNA binding motif protein 39 0.0230916
IPMK inositol polyphosphate multikinase 0.0230698
DOCK5 dedicator of cytokinesis 5 0.0230373
RBM25 RNA binding motif protein 25 0.022809
ATP1B1 ATPase, Na+/K+ transporting, beta 1 polypeptide 0.0228061
SNX13 sorting nexin 13 0.0226743
CCNG2 cyclin G2 0.0226531
ZMYND8 zinc finger, MYND-type containing 8 0.0226475
HIVEP3 human immunodeficiency virus type I enhancer binding protein 3 0.022566
SMOX spermine oxidase 0.0223215
KLHL5 kelch-like family member 5 0.022279
CCNL1 cyclin L1 0.0221299
SMC5 structural maintenance of chromosomes 5 0.0216736
DENND5B DENN/MADD domain containing 5B 0.0216699
NRIP1 nuclear receptor interacting protein 1 0.0216115
SLTM SAFB-like, transcription modulator 0.0213196
SERINC3 serine incorporator 3 0.0211516
MBNL2 muscleblind-like splicing regulator 2 0.0211071
PRKCSH protein kinase C substrate 80K-H 0.0210601
WDR45B WD repeat domain 45B 0.0210057
TENT5A terminal nucleotidyltransferase 5A 0.0209459
BBX bobby sox homolog (Drosophila) 0.0209384

decreased expression

Symbol Name Standardized Value
NRG1 neuregulin 1 -0.185118
GAPDH glyceraldehyde-3-phosphate dehydrogenase -0.177983
EXT1 exostosin glycosyltransferase 1 -0.158662
PTMA prothymosin, alpha -0.120503
VCL vinculin -0.104698
NTN4 netrin 4 -0.0952536
FN1 fibronectin 1 -0.0847502
HMGA2 high mobility group AT-hook 2 -0.0833195
TMSB10 thymosin beta 10 -0.0819141
SYT1 synaptotagmin I -0.0764856
FTL ferritin, light polypeptide -0.0764242
FTH1 ferritin, heavy polypeptide 1 -0.0693756
ZSWIM6 zinc finger, SWIM-type containing 6 -0.064283
PALLD palladin, cytoskeletal associated protein -0.0558439
ARIH1 ariadne RBR E3 ubiquitin protein ligase 1 -0.0548373
PDLIM5 PDZ and LIM domain 5 -0.0543692
MT2A metallothionein 2A -0.0528907
ATP2B1 ATPase, Ca++ transporting, plasma membrane 1 -0.0515878
GLIS3 GLIS family zinc finger 3 -0.0514998
HSP90AA1 heat shock protein 90kDa alpha (cytosolic), class A member 1 -0.0513824
TBC1D8 TBC1 domain family, member 8 (with GRAM domain) -0.0506793
PHLDA1 pleckstrin homology-like domain, family A, member 1 -0.0487929
NRP1 neuropilin 1 -0.0480689
RACK1 receptor for activated C kinase 1 -0.0476322
KSR1 kinase suppressor of ras 1 -0.0474419
RPS12 ribosomal protein S12 -0.0470519
POTEF POTE ankyrin domain family, member F -0.046912
HSPA5 heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) -0.0459893
CDH11 cadherin 11, type 2, OB-cadherin (osteoblast) -0.0445332
ZNF644 zinc finger protein 644 -0.0441216
PITPNC1 phosphatidylinositol transfer protein, cytoplasmic 1 -0.0428942
RPL26 ribosomal protein L26 -0.0417989
GRB10 growth factor receptor-bound protein 10 -0.0417231
RPL12 ribosomal protein L12 -0.0413717
FHL2 four and a half LIM domains 2 -0.0398994
SHB Src homology 2 domain containing adaptor protein B -0.0394139
NXN nucleoredoxin -0.0391674
ACTG1 actin gamma 1 -0.0390941
TOP1 topoisomerase (DNA) I -0.0386468
RPL35A ribosomal protein L35a -0.03756
MAP4K4 mitogen-activated protein kinase kinase kinase kinase 4 -0.0370453
TFPI tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) -0.0368562
GNB1 guanine nucleotide binding protein (G protein), beta polypeptide 1 -0.0367972
RAB10 RAB10, member RAS oncogene family -0.0360833
RAB7A RAB7A, member RAS oncogene family -0.035486
MAP1B microtubule-associated protein 1B -0.0353613
DNAJC1 DnaJ (Hsp40) homolog, subfamily C, member 1 -0.0353336
DYRK1A dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A -0.0353064
TJP1 tight junction protein 1 -0.0351994
IFI27 interferon, alpha-inducible protein 27 -0.0351395
EGR1 early growth response 1 -0.0332732
INTS6 integrator complex subunit 6 -0.0332559
RPL9 ribosomal protein L9 -0.0331053
ASPH aspartate beta-hydroxylase -0.0322284
VIM vimentin -0.0315493
FBXW11 F-box and WD repeat domain containing 11 -0.0314915
HPCAL1 hippocalcin-like 1 -0.0311506
HIPK2 homeodomain interacting protein kinase 2 -0.0310668
FNDC3A fibronectin type III domain containing 3A -0.0309461
PLCB1 phospholipase C, beta 1 (phosphoinositide-specific) -0.0304331
EPS8 epidermal growth factor receptor pathway substrate 8 -0.0301594
SEPTIN9 septin 9 -0.0300305
UBAP1 ubiquitin associated protein 1 -0.0297305
ZC3HAV1 zinc finger CCCH-type, antiviral 1 -0.029235
ECE1 endothelin converting enzyme 1 -0.028673
SEMA3A sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A -0.0284981
GLCCI1 glucocorticoid induced 1 -0.0282666
RPL34 ribosomal protein L34 -0.0281513
DNAH5 dynein, axonemal, heavy chain 5 -0.028065
UBE2H ubiquitin-conjugating enzyme E2H -0.0279357
KCNMA1 potassium channel, calcium activated large conductance subfamily M alpha, member 1 -0.0279021
WDR1 WD repeat domain 1 -0.0278432
LGALS1 lectin, galactoside-binding, soluble, 1 -0.0273933
AEBP2 AE binding protein 2 -0.0273743
NHS Nance-Horan syndrome (congenital cataracts and dental anomalies) -0.0269742
ARHGAP35 Rho GTPase activating protein 35 -0.0267815
NFAT5 nuclear factor of activated T-cells 5, tonicity-responsive -0.0267461
ETNK1 ethanolamine kinase 1 -0.0267206
RPL23 ribosomal protein L23 -0.0266967
CLIP2 CAP-GLY domain containing linker protein 2 -0.0266336
RPS27 ribosomal protein S27 -0.0262885
HM13 histocompatibility (minor) 13 -0.026269
RCOR1 REST corepressor 1 -0.0261012
RPLP1 ribosomal protein, large, P1 -0.0258574
ZFAND3 zinc finger, AN1-type domain 3 -0.0258244
MYO1E myosin IE -0.0258021
KCNQ5 potassium channel, voltage gated KQT-like subfamily Q, member 5 -0.0257243
RPL37A ribosomal protein L37a -0.0257243
SIK3 SIK family kinase 3 -0.0252996
CTBP2 C-terminal binding protein 2 -0.0251319
EEF1G eukaryotic translation elongation factor 1 gamma -0.0250497
BHLHE40 basic helix-loop-helix family, member e40 -0.0250042
S100A10 S100 calcium binding protein A10 -0.0248715
ZMIZ1 zinc finger, MIZ-type containing 1 -0.0246434
RABGEF1 RAB guanine nucleotide exchange factor (GEF) 1 -0.0242812
RPL11 ribosomal protein L11 -0.0242617
RASAL2 RAS protein activator like 2 -0.0240281
PTPRK protein tyrosine phosphatase, receptor type, K -0.0239331
SLC4A7 solute carrier family 4, sodium bicarbonate cotransporter, member 7 -0.0238219
CCDC138 coiled-coil domain containing 138 -0.0235786