0173570-0000-3690 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

198 genes differentially expressed following the 0173570-0000-3690 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
A4GALT alpha 1,4-galactosyltransferase
ACE angiotensin I converting enzyme
AGPAT4 1-acylglycerol-3-phosphate O-acyltransferase 4
ANXA10 annexin A10
ARID4B AT rich interactive domain 4B (RBP1-like)
ARNT2 aryl-hydrocarbon receptor nuclear translocator 2
BCL2A1 BCL2-related protein A1
BET1L Bet1 golgi vesicular membrane trafficking protein-like
BMP7 bone morphogenetic protein 7
C10ORF10 chromosome 10 open reading frame 10
C19ORF57 chromosome 19 open reading frame 57
CA7 carbonic anhydrase VII
CALML3 calmodulin-like 3
CCL11 chemokine (C-C motif) ligand 11
CD4 CD4 molecule
CDH8 cadherin 8, type 2
CDK18 cyclin-dependent kinase 18
CEACAM4 carcinoembryonic antigen-related cell adhesion molecule 4
CHRNA2 cholinergic receptor, nicotinic, alpha 2 (neuronal)
CLCA1 chloride channel accessory 1
CLDN8 claudin 8
CLPS colipase, pancreatic
CNN1 calponin 1, basic, smooth muscle
CTSG cathepsin G
CYP2C9 cytochrome P450, family 2, subfamily C, polypeptide 9
CYP3A5 cytochrome P450, family 3, subfamily A, polypeptide 5
CYP3A7 cytochrome P450, family 3, subfamily A, polypeptide 7
DDIT4 DNA-damage-inducible transcript 4
DDX3Y DEAD (Asp-Glu-Ala-Asp) box helicase 3, Y-linked
DHX34 DEAH (Asp-Glu-Ala-His) box polypeptide 34
DMBT1 deleted in malignant brain tumors 1
DMXL2 Dmx-like 2
FCN1 ficolin (collagen/fibrinogen domain containing) 1
FMO6P flavin containing monooxygenase 6 pseudogene
FNDC4 fibronectin type III domain containing 4
GAB1 GRB2-associated binding protein 1
GAS2 growth arrest-specific 2
GJB5 gap junction protein, beta 5, 31.1kDa
GRAMD1B GRAM domain containing 1B
HR hair growth associated
HRASLS2 HRAS-like suppressor 2
HRG histidine-rich glycoprotein
IL11 interleukin 11
INA internexin neuronal intermediate filament protein, alpha
ISG20 interferon stimulated exonuclease gene 20kDa
ITGAM integrin, alpha M (complement component 3 receptor 3 subunit)
KCNMA1 potassium channel, calcium activated large conductance subfamily M alpha, member 1
KIAA0040 KIAA0040
KIF26B kinesin family member 26B
LILRA4 leukocyte immunoglobulin-like receptor, subfamily A (with TM domain), member 4
LRIG1 leucine-rich repeats and immunoglobulin-like domains 1
LRP1 low density lipoprotein receptor-related protein 1
LRRN3 leucine rich repeat neuronal 3
LSS lanosterol synthase (2,3-oxidosqualene-lanosterol cyclase)
MAP2K6 mitogen-activated protein kinase kinase 6
MAP3K13 mitogen-activated protein kinase kinase kinase 13
MMP25 matrix metallopeptidase 25
MPPE1 metallophosphoesterase 1
MRC2 mannose receptor, C type 2
MUC5B mucin 5B, oligomeric mucus/gel-forming
MYO15A myosin XVA
NPIPB15 nuclear pore complex interacting protein family, member B15
NR4A2 nuclear receptor subfamily 4, group A, member 2
OASL 2'-5'-oligoadenylate synthetase-like
PALM paralemmin
PART1 prostate androgen-regulated transcript 1 (non-protein coding)
PCSK6 proprotein convertase subtilisin/kexin type 6
PDE3B phosphodiesterase 3B, cGMP-inhibited
PDE4B phosphodiesterase 4B, cAMP-specific
PDE6B phosphodiesterase 6B, cGMP-specific, rod, beta
PHC3 polyhomeotic homolog 3 (Drosophila)
PIK3R5 phosphoinositide-3-kinase, regulatory subunit 5
PLA2G3 phospholipase A2, group III
PLEKHG3 pleckstrin homology domain containing, family G (with RhoGef domain) member 3
POU2F2 POU class 2 homeobox 2
PRB1 proline-rich protein BstNI subfamily 1
PTCH1 patched 1
PTGDS prostaglandin D2 synthase 21kDa (brain)
PTGES prostaglandin E synthase
PTGIS prostaglandin I2 (prostacyclin) synthase
QPCTL glutaminyl-peptide cyclotransferase-like
RGS5 regulator of G-protein signaling 5
RND1 Rho family GTPase 1
SERPINB3 serpin peptidase inhibitor, clade B (ovalbumin), member 3
SH3BP1 SH3-domain binding protein 1
SIRT4 sirtuin 4
SLC15A2 solute carrier family 15 (oligopeptide transporter), member 2
SLC2A11 solute carrier family 2 (facilitated glucose transporter), member 11
SMOX spermine oxidase
SNCG synuclein, gamma (breast cancer-specific protein 1)
SOX15 SRY (sex determining region Y)-box 15
SPAG8 sperm associated antigen 8
STAT2 signal transducer and activator of transcription 2, 113kDa
STC1 stanniocalcin 1
TFEB transcription factor EB
THY1 Thy-1 cell surface antigen
TJP3 tight junction protein 3
TNFSF15 tumor necrosis factor (ligand) superfamily, member 15
TTLL4 tubulin tyrosine ligase-like family member 4
VIPR2 vasoactive intestinal peptide receptor 2

decreased expression

Symbol Name
ACTR8 ARP8 actin-related protein 8 homolog (yeast)
ADRB2 adrenoceptor beta 2, surface
AMIGO2 adhesion molecule with Ig-like domain 2
ASAP1 ArfGAP with SH3 domain, ankyrin repeat and PH domain 1
ASAP1-IT1 ASAP1 intronic transcript 1
ATAD5 ATPase family, AAA domain containing 5
ATG16L1 autophagy related 16-like 1 (S. cerevisiae)
BBS7 Bardet-Biedl syndrome 7
BRIP1 BRCA1 interacting protein C-terminal helicase 1
C17ORF53 chromosome 17 open reading frame 53
CABYR calcium binding tyrosine-(Y)-phosphorylation regulated
CCDC6 coiled-coil domain containing 6
CCNB2 cyclin B2
CENPE centromere protein E, 312kDa
CENPJ centromere protein J
CEP295 centrosomal protein 295kDa
CHRM3 cholinergic receptor, muscarinic 3
CHRNA5 cholinergic receptor, nicotinic, alpha 5 (neuronal)
CTGF connective tissue growth factor
CYP27A1 cytochrome P450, family 27, subfamily A, polypeptide 1
DCBLD2 discoidin, CUB and LCCL domain containing 2
DEPDC1 DEP domain containing 1
DLGAP5 discs, large (Drosophila) homolog-associated protein 5
DNAJA4 DnaJ (Hsp40) homolog, subfamily A, member 4
EGR2 early growth response 2
EML4 echinoderm microtubule associated protein like 4
EXOC6B exocyst complex component 6B
FAM64A family with sequence similarity 64, member A
FGD6 FYVE, RhoGEF and PH domain containing 6
GALK1 galactokinase 1
GBX2 gastrulation brain homeobox 2
GLS2 glutaminase 2 (liver, mitochondrial)
GPR176 G protein-coupled receptor 176
GTF2A1 general transcription factor IIA, 1, 19/37kDa
HIST1H1D histone cluster 1, H1d
HIST1H2AM histone cluster 1, H2am
HIST1H3C histone cluster 1, H3c
HIST1H4C histone cluster 1, H4c
HMMR hyaluronan-mediated motility receptor (RHAMM)
HSPA14 heat shock 70kDa protein 14
IFNAR1 interferon (alpha, beta and omega) receptor 1
IGFLR1 IGF-like family receptor 1
KCNS1 potassium voltage-gated channel, modifier subfamily S, member 1
KIAA1549L KIAA1549-like
KIF20A kinesin family member 20A
LIFR leukemia inhibitory factor receptor alpha
LINS lines homolog (Drosophila)
LIPG lipase, endothelial
MBNL3 muscleblind-like splicing regulator 3
MCC mutated in colorectal cancers
MEFV Mediterranean fever
MFHAS1 malignant fibrous histiocytoma amplified sequence 1
MFSD6 major facilitator superfamily domain containing 6
MMP3 matrix metallopeptidase 3
MN1 meningioma (disrupted in balanced translocation) 1
MOXD1 monooxygenase, DBH-like 1
MXRA8 matrix-remodelling associated 8
NDC80 NDC80 kinetochore complex component
NEK2 NIMA-related kinase 2
NR1D2 nuclear receptor subfamily 1, group D, member 2
NUP62CL nucleoporin 62kDa C-terminal like
P2RX4 purinergic receptor P2X, ligand gated ion channel, 4
PADI1 peptidyl arginine deiminase, type I
PAQR3 progestin and adipoQ receptor family member III
PIGQ phosphatidylinositol glycan anchor biosynthesis, class Q
PLEKHA2 pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 2
PLEKHO1 pleckstrin homology domain containing, family O member 1
PLK1 polo-like kinase 1
POLR3D polymerase (RNA) III (DNA directed) polypeptide D, 44kDa
PSRC1 proline/serine-rich coiled-coil 1
PWAR5 Prader Willi/Angelman region RNA 5
QSER1 glutamine and serine rich 1
RASL11B RAS-like, family 11, member B
RASSF1 Ras association (RalGDS/AF-6) domain family member 1
RRAGB Ras-related GTP binding B
SAYSD1 SAYSVFN motif domain containing 1
SERPINE1 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1
SIRAL2 SIR2 antiphage like 2
SKI SKI proto-oncogene
SLC22A14 solute carrier family 22, member 14
SLC46A3 solute carrier family 46, member 3
SLC9A8 solute carrier family 9, subfamily A (NHE8, cation proton antiporter 8), member 8
SMPD2 sphingomyelin phosphodiesterase 2, neutral membrane (neutral sphingomyelinase)
SPC25 SPC25, NDC80 kinetochore complex component
SUZ12P1 suppressor of zeste 12 homolog pseudogene 1
TANC2 tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2
TIMP4 TIMP metallopeptidase inhibitor 4
TIPARP TCDD-inducible poly(ADP-ribose) polymerase
TMEM156 transmembrane protein 156
TOMM22 translocase of outer mitochondrial membrane 22 homolog (yeast)
TRDMT1 tRNA aspartic acid methyltransferase 1
TRPV6 transient receptor potential cation channel, subfamily V, member 6
TTPAL tocopherol (alpha) transfer protein-like
TUBA3C tubulin, alpha 3c
UBE2S ubiquitin-conjugating enzyme E2S
UNC93B1 unc-93 homolog B1 (C. elegans)
WFDC2 WAP four-disulfide core domain 2
ZW10 zw10 kinetochore protein