0173570-0000-3693 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

197 genes differentially expressed following the 0173570-0000-3693 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ACO2 aconitase 2, mitochondrial
AMN amnion associated transmembrane protein
ANGPTL4 angiopoietin-like 4
ARVCF armadillo repeat gene deleted in velocardiofacial syndrome
B9D1 B9 protein domain 1
BATF basic leucine zipper transcription factor, ATF-like
BCL2A1 BCL2-related protein A1
BMP2 bone morphogenetic protein 2
C18ORF25 chromosome 18 open reading frame 25
CALCR calcitonin receptor
CD79A CD79a molecule, immunoglobulin-associated alpha
CDH15 cadherin 15, type 1, M-cadherin (myotubule)
CHRNA1 cholinergic receptor, nicotinic, alpha 1 (muscle)
CHRNA2 cholinergic receptor, nicotinic, alpha 2 (neuronal)
CHRNA3 cholinergic receptor, nicotinic, alpha 3 (neuronal)
COL1A2 collagen, type I, alpha 2
COPZ2 coatomer protein complex, subunit zeta 2
CWH43 cell wall biogenesis 43 C-terminal homolog (S. cerevisiae)
DDIT4 DNA-damage-inducible transcript 4
DDX11 DEAD/H (Asp-Glu-Ala-Asp/His) box helicase 11
DMBT1 deleted in malignant brain tumors 1
EML2 echinoderm microtubule associated protein like 2
ENG endoglin
EPX eosinophil peroxidase
EXOG endo/exonuclease (5'-3'), endonuclease G-like
FASLG Fas ligand (TNF superfamily, member 6)
FOXO4 forkhead box O4
GFI1 growth factor independent 1 transcription repressor
GJA4 gap junction protein, alpha 4, 37kDa
GPLD1 glycosylphosphatidylinositol specific phospholipase D1
GPR137 G protein-coupled receptor 137
GPR161 G protein-coupled receptor 161
GRAMD1B GRAM domain containing 1B
GRK4 G protein-coupled receptor kinase 4
HERPUD1 homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1
HOMER3 homer scaffolding protein 3
IDH2 isocitrate dehydrogenase 2 (NADP+), mitochondrial
IDS iduronate 2-sulfatase
IFNA14 interferon, alpha 14
IGF1 insulin-like growth factor 1 (somatomedin C)
IL17RC interleukin 17 receptor C
IL32 interleukin 32
IL36G interleukin 36, gamma
ING1 inhibitor of growth family, member 1
IRF4 interferon regulatory factor 4
ITGA7 integrin, alpha 7
KDM4B lysine (K)-specific demethylase 4B
KLF1 Kruppel-like factor 1 (erythroid)
KLF13 Kruppel-like factor 13
KREMEN2 kringle containing transmembrane protein 2
LGALS9 lectin, galactoside-binding, soluble, 9
LSS lanosterol synthase (2,3-oxidosqualene-lanosterol cyclase)
MAP2K5 mitogen-activated protein kinase kinase 5
MBD2 methyl-CpG binding domain protein 2
MEF2D myocyte enhancer factor 2D
MFAP2 microfibrillar-associated protein 2
MFSD7 major facilitator superfamily domain containing 7
MOG myelin oligodendrocyte glycoprotein
MRC2 mannose receptor, C type 2
N4BP1 NEDD4 binding protein 1
NDUFAF5 NADH dehydrogenase (ubiquinone) complex I, assembly factor 5
NF1 neurofibromin 1
NUDT7 nudix (nucleoside diphosphate linked moiety X)-type motif 7
OSMR oncostatin M receptor
PBX2 pre-B-cell leukemia homeobox 2
PCBP3 poly(rC) binding protein 3
PDE12 phosphodiesterase 12
PDE4B phosphodiesterase 4B, cAMP-specific
PDK4 pyruvate dehydrogenase kinase, isozyme 4
PDPN podoplanin
PIK3IP1 phosphoinositide-3-kinase interacting protein 1
PRKCI protein kinase C, iota
PYY peptide YY
RAB26 RAB26, member RAS oncogene family
RELB v-rel avian reticuloendotheliosis viral oncogene homolog B
RGS5 regulator of G-protein signaling 5
RHAG Rh-associated glycoprotein
SAYSD1 SAYSVFN motif domain containing 1
SDHB succinate dehydrogenase complex, subunit B, iron sulfur (Ip)
SELL selectin L
SEMA4D sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4D
SEMA4F sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4F
SEMA5A sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5A
SEMA7A semaphorin 7A, GPI membrane anchor (John Milton Hagen blood group)
SFI1 Sfi1 homolog, spindle assembly associated (yeast)
SH2D3A SH2 domain containing 3A
SLC45A2 solute carrier family 45, member 2
SRPK3 SRSF protein kinase 3
SRSF7 serine/arginine-rich splicing factor 7
STC1 stanniocalcin 1
TAT tyrosine aminotransferase
TBC1D30 TBC1 domain family, member 30
TCP10 t-complex 10
TFEB transcription factor EB
TNFSF4 tumor necrosis factor (ligand) superfamily, member 4
TRIM29 tripartite motif containing 29
UCHL1 ubiquitin carboxyl-terminal esterase L1 (ubiquitin thiolesterase)
WT1 Wilms tumor 1
ZNF362 zinc finger protein 362

decreased expression

Symbol Name
ADGRL2 adhesion G protein-coupled receptor L2
ADTRP androgen-dependent TFPI-regulating protein
AEN apoptosis enhancing nuclease
AGMAT agmatine ureohydrolase (agmatinase)
ALOX12P2 arachidonate 12-lipoxygenase pseudogene 2
ALPK1 alpha-kinase 1
APBB1 amyloid beta (A4) precursor protein-binding, family B, member 1 (Fe65)
ARC activity-regulated cytoskeleton-associated protein
C17ORF53 chromosome 17 open reading frame 53
C9ORF9 chromosome 9 open reading frame 9
CA9 carbonic anhydrase IX
CABYR calcium binding tyrosine-(Y)-phosphorylation regulated
CACNG4 calcium channel, voltage-dependent, gamma subunit 4
CBX8 chromobox homolog 8
CDON cell adhesion associated, oncogene regulated
CENPJ centromere protein J
CES3 carboxylesterase 3
CHRNA10 cholinergic receptor, nicotinic, alpha 10 (neuronal)
CNTNAP3B contactin associated protein-like 3B
COBL cordon-bleu WH2 repeat protein
CPA4 carboxypeptidase A4
CREB5 cAMP responsive element binding protein 5
DAGLA diacylglycerol lipase, alpha
DENND2D DENN/MADD domain containing 2D
DGKE diacylglycerol kinase, epsilon 64kDa
DNAJC28 DnaJ (Hsp40) homolog, subfamily C, member 28
DOK5 docking protein 5
EGFL7 EGF-like-domain, multiple 7
EHF ets homologous factor
EPHA4 EPH receptor A4
ERN2 endoplasmic reticulum to nucleus signaling 2
ETV6 ets variant 6
EYA4 EYA transcriptional coactivator and phosphatase 4
FAM105A family with sequence similarity 105, member A
FBXL7 F-box and leucine-rich repeat protein 7
FBXO46 F-box protein 46
FOXC1 forkhead box C1
GBP2 guanylate binding protein 2, interferon-inducible
GNAT2 guanine nucleotide binding protein (G protein), alpha transducing activity polypeptide 2
GNL3LP1 guanine nucleotide binding protein-like 3 (nucleolar)-like pseudogene 1
HIST1H1D histone cluster 1, H1d
HIST1H3C histone cluster 1, H3c
HIST1H4A histone cluster 1, H4a
HOXA2 homeobox A2
HOXC4 homeobox C4
HSD17B1 hydroxysteroid (17-beta) dehydrogenase 1
IFI6 interferon, alpha-inducible protein 6
INCENP inner centromere protein antigens 135/155kDa
ITIH2 inter-alpha-trypsin inhibitor heavy chain 2
KIFC3 kinesin family member C3
LHPP phospholysine phosphohistidine inorganic pyrophosphate phosphatase
LMO2 LIM domain only 2 (rhombotin-like 1)
LMTK2 lemur tyrosine kinase 2
LRRK1 leucine-rich repeat kinase 1
MAGEH1 melanoma antigen family H1
MAK male germ cell-associated kinase
MAP3K7CL MAP3K7 C-terminal like
MMP3 matrix metallopeptidase 3
MMP9 matrix metallopeptidase 9
MOXD1 monooxygenase, DBH-like 1
MRAS muscle RAS oncogene homolog
NEK11 NIMA-related kinase 11
NIPAL2 NIPA-like domain containing 2
NT5DC3 5'-nucleotidase domain containing 3
ODF2 outer dense fiber of sperm tails 2
OR1D2 olfactory receptor, family 1, subfamily D, member 2
PDE8B phosphodiesterase 8B
PLBD1 phospholipase B domain containing 1
PMCH pro-melanin-concentrating hormone
PQLC2 PQ loop repeat containing 2
PROL1 proline rich, lacrimal 1
PWAR5 Prader Willi/Angelman region RNA 5
RASL11B RAS-like, family 11, member B
RPGRIP1L RPGRIP1-like
RPRM reprimo, TP53 dependent G2 arrest mediator candidate
SERPINI1 serpin peptidase inhibitor, clade I (neuroserpin), member 1
SETD8 SET domain containing (lysine methyltransferase) 8
SLC2A9 solute carrier family 2 (facilitated glucose transporter), member 9
SLN sarcolipin
SMA4 glucuronidase, beta pseudogene
SPTLC3 serine palmitoyltransferase, long chain base subunit 3
SSTR5 somatostatin receptor 5
ST6GALNAC5 ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 5
SYCP2 synaptonemal complex protein 2
TAF15 TAF15 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 68kDa
TAOK1 TAO kinase 1
TBKBP1 TBK1 binding protein 1
TFCP2L1 transcription factor CP2-like 1
TIPARP TCDD-inducible poly(ADP-ribose) polymerase
TMEM180 transmembrane protein 180
TMEM212 transmembrane protein 212
TNFSF12 tumor necrosis factor (ligand) superfamily, member 12
TPCN1 two pore segment channel 1
YPEL1 yippee-like 1 (Drosophila)
ZBTB3 zinc finger and BTB domain containing 3
ZCWPW1 zinc finger, CW type with PWWP domain 1
ZMAT5 zinc finger, matrin-type 5
ZNF749 zinc finger protein 749