0173570-0000-4715 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

194 genes differentially expressed following the 0173570-0000-4715 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ACRV1 acrosomal vesicle protein 1
ADCK4 aarF domain containing kinase 4
ANP32A-IT1 ANP32A intronic transcript 1
AQP3 aquaporin 3 (Gill blood group)
ARHGEF1 Rho guanine nucleotide exchange factor (GEF) 1
CA4 carbonic anhydrase IV
CD58 CD58 molecule
CLEC4A C-type lectin domain family 4, member A
CSPP1 centrosome and spindle pole associated protein 1
CTBP2 C-terminal binding protein 2
CYLD cylindromatosis (turban tumor syndrome)
DGKE diacylglycerol kinase, epsilon 64kDa
DMXL2 Dmx-like 2
DOCK3 dedicator of cytokinesis 3
EFS embryonal Fyn-associated substrate
EHD2 EH-domain containing 2
ERO1LB ERO1-like beta (S. cerevisiae)
F2R coagulation factor II (thrombin) receptor
F2RL2 coagulation factor II (thrombin) receptor-like 2
FGFR3 fibroblast growth factor receptor 3
FLCN folliculin
GATM glycine amidinotransferase (L-arginine:glycine amidinotransferase)
GBP2 guanylate binding protein 2, interferon-inducible
GFI1 growth factor independent 1 transcription repressor
GLYR1 glyoxylate reductase 1 homolog (Arabidopsis)
GPRC5D G protein-coupled receptor, class C, group 5, member D
HERC2P3 hect domain and RLD 2 pseudogene 3
HPSE2 heparanase 2 (inactive)
HSD3B2 hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 2
ICAM1 intercellular adhesion molecule 1
IL11 interleukin 11
INO80D INO80 complex subunit D
IPW imprinted in Prader-Willi syndrome (non-protein coding)
LAMA4 laminin, alpha 4
LINC00341 long intergenic non-protein coding RNA 341
LRRC37A3 leucine rich repeat containing 37, member A3
LZTS3 leucine zipper, putative tumor suppressor family member 3
MAP2K5 mitogen-activated protein kinase kinase 5
MAPK10 mitogen-activated protein kinase 10
MAU2 MAU2 sister chromatid cohesion factor
MTMR8 myotubularin related protein 8
NBL1 neuroblastoma 1, DAN family BMP antagonist
NCKIPSD NCK interacting protein with SH3 domain
NME5 NME/NM23 family member 5
NOX3 NADPH oxidase 3
NUP54 nucleoporin 54kDa
ONECUT2 one cut homeobox 2
PAFAH2 platelet-activating factor acetylhydrolase 2, 40kDa
PARP8 poly (ADP-ribose) polymerase family, member 8
PDE8B phosphodiesterase 8B
PHYHIP phytanoyl-CoA 2-hydroxylase interacting protein
PIP prolactin-induced protein
PLEKHS1 pleckstrin homology domain containing, family S member 1
PLK4 polo-like kinase 4
PMP2 peripheral myelin protein 2
PPARG peroxisome proliferator-activated receptor gamma
PPIL2 peptidylprolyl isomerase (cyclophilin)-like 2
PRB1 proline-rich protein BstNI subfamily 1
PRKCA protein kinase C, alpha
PRKCE protein kinase C, epsilon
QSER1 glutamine and serine rich 1
RAB11B RAB11B, member RAS oncogene family
RAB36 RAB36, member RAS oncogene family
RAB6B RAB6B, member RAS oncogene family
RAG2 recombination activating gene 2
RALGPS2 Ral GEF with PH domain and SH3 binding motif 2
RFPL3 ret finger protein-like 3
RHBG Rh family, B glycoprotein (gene/pseudogene)
RMND5A required for meiotic nuclear division 5 homolog A (S. cerevisiae)
RPL10L ribosomal protein L10-like
RPL35A ribosomal protein L35a
RPS28 ribosomal protein S28
RPS3A ribosomal protein S3A
SAP30 Sin3A-associated protein, 30kDa
SCAND2P SCAN domain containing 2 pseudogene
SEMA3B sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3B
SEMA3F sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3F
SENP5 SUMO1/sentrin specific peptidase 5
SLC4A4 solute carrier family 4 (sodium bicarbonate cotransporter), member 4
SLC9A3 solute carrier family 9, subfamily A (NHE3, cation proton antiporter 3), member 3
SLCO2A1 solute carrier organic anion transporter family, member 2A1
SMARCD3 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 3
SP100 SP100 nuclear antigen
SPTLC2 serine palmitoyltransferase, long chain base subunit 2
STAG3L4 stromal antigen 3-like 4 (pseudogene)
SUZ12P1 suppressor of zeste 12 homolog pseudogene 1
TCF4 transcription factor 4
TCP10 t-complex 10
TGFB1 transforming growth factor, beta 1
THOC5 THO complex 5
TRIM31 tripartite motif containing 31
TTC38 tetratricopeptide repeat domain 38
UHRF1BP1L UHRF1 binding protein 1-like
VEZT vezatin, adherens junctions transmembrane protein
VPS45 vacuolar protein sorting 45 homolog (S. cerevisiae)
ZMYND8 zinc finger, MYND-type containing 8
ZNF112 zinc finger protein 112
ZNF304 zinc finger protein 304

decreased expression

Symbol Name
ACSL4 acyl-CoA synthetase long-chain family member 4
ACTL8 actin-like 8
ALDH1A3 aldehyde dehydrogenase 1 family, member A3
APBB3 amyloid beta (A4) precursor protein-binding, family B, member 3
ARC activity-regulated cytoskeleton-associated protein
ARHGAP4 Rho GTPase activating protein 4
ARHGEF17 Rho guanine nucleotide exchange factor (GEF) 17
BBC3 BCL2 binding component 3
BCOR BCL6 corepressor
C11ORF63 chromosome 11 open reading frame 63
C12ORF4 chromosome 12 open reading frame 4
C21ORF91 chromosome 21 open reading frame 91
C22ORF46 chromosome 22 open reading frame 46
C2ORF27A chromosome 2 open reading frame 27A
CAPN5 calpain 5
CBX7 chromobox homolog 7
CCNO cyclin O
CDHR2 cadherin-related family member 2
CENPO centromere protein O
CHMP6 charged multivesicular body protein 6
CNKSR1 connector enhancer of kinase suppressor of Ras 1
CSF1R colony stimulating factor 1 receptor
CST6 cystatin E/M
CSTA cystatin A (stefin A)
CTC1 CTS telomere maintenance complex component 1
CTIF CBP80/20-dependent translation initiation factor
CUEDC1 CUE domain containing 1
CYP1A1 cytochrome P450, family 1, subfamily A, polypeptide 1
DDX54 DEAD (Asp-Glu-Ala-Asp) box polypeptide 54
EAF2 ELL associated factor 2
EFNA3 ephrin-A3
EGLN3 egl-9 family hypoxia-inducible factor 3
FAM188A family with sequence similarity 188, member A
FBXW4P1 F-box and WD repeat domain containing 4 pseudogene 1
FGD6 FYVE, RhoGEF and PH domain containing 6
FILIP1L filamin A interacting protein 1-like
GATA4 GATA binding protein 4
GEMIN8 gem (nuclear organelle) associated protein 8
GNG4 guanine nucleotide binding protein (G protein), gamma 4
HIST2H2AA3 histone cluster 2, H2aa3
HIVEP3 human immunodeficiency virus type I enhancer binding protein 3
HSD17B14 hydroxysteroid (17-beta) dehydrogenase 14
JMJD4 jumonji domain containing 4
KLHL25 kelch-like family member 25
MAP3K8 mitogen-activated protein kinase kinase kinase 8
MBTPS2 membrane-bound transcription factor peptidase, site 2
MEIS1 Meis homeobox 1
METTL16 methyltransferase like 16
MRPL52 mitochondrial ribosomal protein L52
MUC3A mucin 3A, cell surface associated
NEUROD1 neuronal differentiation 1
NEUROD4 neuronal differentiation 4
NFE2L3 nuclear factor, erythroid 2-like 3
NFKBIB nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, beta
NPIPB15 nuclear pore complex interacting protein family, member B15
NUS1P3 nuclear undecaprenyl pyrophosphate synthase 1 homolog (S. cerevisiae) pseudogene 3
OGFRL1 opioid growth factor receptor-like 1
PDE6C phosphodiesterase 6C, cGMP-specific, cone, alpha prime
PIGN phosphatidylinositol glycan anchor biosynthesis, class N
PLCB3 phospholipase C, beta 3 (phosphatidylinositol-specific)
PMEL premelanosome protein
PRPH peripherin
PVRL3 poliovirus receptor-related 3
RBL1 retinoblastoma-like 1
RGS17 regulator of G-protein signaling 17
RIN1 Ras and Rab interactor 1
RUSC2 RUN and SH3 domain containing 2
SAA3P serum amyloid A3 pseudogene
SKI SKI proto-oncogene
SLC12A8 solute carrier family 12, member 8
SLC8B1 solute carrier family 8 (sodium/lithium/calcium exchanger), member B1
SPAG4 sperm associated antigen 4
SPINK4 serine peptidase inhibitor, Kazal type 4
TEAD3 TEA domain family member 3
THNSL2 threonine synthase-like 2 (S. cerevisiae)
THOP1 thimet oligopeptidase 1
TMEM53 transmembrane protein 53
TNFSF9 tumor necrosis factor (ligand) superfamily, member 9
TRIM5 tripartite motif containing 5
TTC23 tetratricopeptide repeat domain 23
TUBB2B tubulin, beta 2B class IIb
UPK2 uroplakin 2
UPP1 uridine phosphorylase 1
USB1 U6 snRNA biogenesis 1
VEGFB vascular endothelial growth factor B
VGF VGF nerve growth factor inducible
VIPR1 vasoactive intestinal peptide receptor 1
VPS33A vacuolar protein sorting 33 homolog A (S. cerevisiae)
WDR25 WD repeat domain 25
ZDHHC14 zinc finger, DHHC-type containing 14
ZNF134 zinc finger protein 134
ZNF141 zinc finger protein 141
ZNF276 zinc finger protein 276
ZNF446 zinc finger protein 446
ZNF510 zinc finger protein 510
ZNF816 zinc finger protein 816