0173570-0000-7389 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

200 genes differentially expressed following the 0173570-0000-7389 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ABCB6 ATP-binding cassette, sub-family B (MDR/TAP), member 6 (Langereis blood group)
ABHD6 abhydrolase domain containing 6
AP1S1 adaptor-related protein complex 1, sigma 1 subunit
APBB2 amyloid beta (A4) precursor protein-binding, family B, member 2
ARL15 ADP-ribosylation factor-like 15
AVPI1 arginine vasopressin-induced 1
BCL2A1 BCL2-related protein A1
C1R complement component 1, r subcomponent
CACNB3 calcium channel, voltage-dependent, beta 3 subunit
CADM3 cell adhesion molecule 3
CD55 CD55 molecule, decay accelerating factor for complement (Cromer blood group)
CDH15 cadherin 15, type 1, M-cadherin (myotubule)
CDK5R1 cyclin-dependent kinase 5, regulatory subunit 1 (p35)
CDKL3 cyclin-dependent kinase-like 3
CDKN1C cyclin-dependent kinase inhibitor 1C (p57, Kip2)
CRELD1 cysteine-rich with EGF-like domains 1
CREM cAMP responsive element modulator
CSGALNACT1 chondroitin sulfate N-acetylgalactosaminyltransferase 1
CST4 cystatin S
CTH cystathionine gamma-lyase
CUL7 cullin 7
CXCL2 chemokine (C-X-C motif) ligand 2
CXCL3 chemokine (C-X-C motif) ligand 3
CYP27A1 cytochrome P450, family 27, subfamily A, polypeptide 1
DDIT3 DNA-damage-inducible transcript 3
DDIT4 DNA-damage-inducible transcript 4
DFNB31 deafness, autosomal recessive 31
DHODH dihydroorotate dehydrogenase (quinone)
DIS3 DIS3 exosome endoribonuclease and 3'-5' exoribonuclease
DLC1 DLC1 Rho GTPase activating protein
DMBT1 deleted in malignant brain tumors 1
DOHH deoxyhypusine hydroxylase/monooxygenase
DUSP1 dual specificity phosphatase 1
EFNA3 ephrin-A3
FA2H fatty acid 2-hydroxylase
FKBP8 FK506 binding protein 8, 38kDa
FOXN3 forkhead box N3
FURIN furin (paired basic amino acid cleaving enzyme)
GALNT12 polypeptide N-acetylgalactosaminyltransferase 12
GLRX3 glutaredoxin 3
GMEB1 glucocorticoid modulatory element binding protein 1
GRAMD1B GRAM domain containing 1B
HERPUD1 homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1
HNRNPD heterogeneous nuclear ribonucleoprotein D (AU-rich element RNA binding protein 1, 37kDa)
HOXA4 homeobox A4
HS1BP3 HCLS1 binding protein 3
HTR7 5-hydroxytryptamine (serotonin) receptor 7, adenylate cyclase-coupled
IGFLR1 IGF-like family receptor 1
IL11 interleukin 11
IL15 interleukin 15
IL6 interleukin 6
ISG20 interferon stimulated exonuclease gene 20kDa
ITPR1 inositol 1,4,5-trisphosphate receptor, type 1
KCNMA1 potassium channel, calcium activated large conductance subfamily M alpha, member 1
KRT6B keratin 6B, type II
MAP2K6 mitogen-activated protein kinase kinase 6
MAP7 microtubule-associated protein 7
MPPE1 metallophosphoesterase 1
MR1 major histocompatibility complex, class I-related
NR4A2 nuclear receptor subfamily 4, group A, member 2
NRTN neurturin
OASL 2'-5'-oligoadenylate synthetase-like
PBXIP1 pre-B-cell leukemia homeobox interacting protein 1
PDLIM4 PDZ and LIM domain 4
PDZK1 PDZ domain containing 1
PGLYRP4 peptidoglycan recognition protein 4
PHLDB1 pleckstrin homology-like domain, family B, member 1
PKP3 plakophilin 3
PLEKHM1 pleckstrin homology domain containing, family M (with RUN domain) member 1
PLSCR4 phospholipid scramblase 4
PPP4R4 protein phosphatase 4, regulatory subunit 4
PPP5C protein phosphatase 5, catalytic subunit
PTGES prostaglandin E synthase
PTP4A1 protein tyrosine phosphatase type IVA, member 1
R3HCC1L R3H domain and coiled-coil containing 1-like
RABGAP1 RAB GTPase activating protein 1
RECK reversion-inducing-cysteine-rich protein with kazal motifs
SARS2 seryl-tRNA synthetase 2, mitochondrial
SC5D sterol-C5-desaturase
SEMA3F sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3F
SGSM3 small G protein signaling modulator 3
SLC8A1 solute carrier family 8 (sodium/calcium exchanger), member 1
SLMO1 slowmo homolog 1 (Drosophila)
SMIM7 small integral membrane protein 7
SMOX spermine oxidase
SPATA2L spermatogenesis associated 2-like
STC1 stanniocalcin 1
SUGP1 SURP and G patch domain containing 1
TANC2 tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2
TAOK2 TAO kinase 2
TNFAIP3 tumor necrosis factor, alpha-induced protein 3
TNIK TRAF2 and NCK interacting kinase
TNK1 tyrosine kinase, non-receptor, 1
TRIB3 tribbles pseudokinase 3
VAPB VAMP (vesicle-associated membrane protein)-associated protein B and C
YTHDC1 YTH domain containing 1
ZBTB20 zinc finger and BTB domain containing 20
ZNF276 zinc finger protein 276
ZNF358 zinc finger protein 358
ZNF606 zinc finger protein 606

decreased expression

Symbol Name
ADGRF1 adhesion G protein-coupled receptor F1
ADORA2B adenosine A2b receptor
ADRB2 adrenoceptor beta 2, surface
ALPK1 alpha-kinase 1
AMIGO2 adhesion molecule with Ig-like domain 2
APOL6 apolipoprotein L, 6
ASPM asp (abnormal spindle) homolog, microcephaly associated (Drosophila)
C11ORF68 chromosome 11 open reading frame 68
C16ORF62 chromosome 16 open reading frame 62
CABYR calcium binding tyrosine-(Y)-phosphorylation regulated
CCNA2 cyclin A2
CCNB1 cyclin B1
CCNB2 cyclin B2
CDC20 cell division cycle 20
CDC25B cell division cycle 25B
CDC42EP1 CDC42 effector protein (Rho GTPase binding) 1
CDCA3 cell division cycle associated 3
CDCA8 cell division cycle associated 8
CDH7 cadherin 7, type 2
CDK3 cyclin-dependent kinase 3
CDK6 cyclin-dependent kinase 6
CDK9 cyclin-dependent kinase 9
CENPE centromere protein E, 312kDa
CENPF centromere protein F, 350/400kDa
CENPO centromere protein O
CEP85 centrosomal protein 85kDa
CHEK2 checkpoint kinase 2
CHML choroideremia-like (Rab escort protein 2)
CKS2 CDC28 protein kinase regulatory subunit 2
CLDN14 claudin 14
CLDN4 claudin 4
CLEC10A C-type lectin domain family 10, member A
CTGF connective tissue growth factor
DBF4 DBF4 zinc finger
DEPDC1 DEP domain containing 1
DLEU2 deleted in lymphocytic leukemia 2 (non-protein coding)
DLGAP5 discs, large (Drosophila) homolog-associated protein 5
DNMT3B DNA (cytosine-5-)-methyltransferase 3 beta
ELSPBP1 epididymal sperm binding protein 1
EN2 engrailed homeobox 2
EPHA4 EPH receptor A4
FAM64A family with sequence similarity 64, member A
FBXL2 F-box and leucine-rich repeat protein 2
GABPA GA binding protein transcription factor, alpha subunit 60kDa
GBX2 gastrulation brain homeobox 2
GPSM2 G-protein signaling modulator 2
GRPR gastrin-releasing peptide receptor
GRWD1 glutamate-rich WD repeat containing 1
HIST1H2AG histone cluster 1, H2ag
HJURP Holliday junction recognition protein
HMGB3 high mobility group box 3
HMMR hyaluronan-mediated motility receptor (RHAMM)
IL24 interleukin 24
IPPK inositol 1,3,4,5,6-pentakisphosphate 2-kinase
KIF11 kinesin family member 11
KIF14 kinesin family member 14
KIF20A kinesin family member 20A
KIF20B kinesin family member 20B
KIF23 kinesin family member 23
KIF2C kinesin family member 2C
KIF4A kinesin family member 4A
LOC202181 SUMO-interacting motifs containing 1 pseudogene
MFSD12 major facilitator superfamily domain containing 12
MOCS3 molybdenum cofactor synthesis 3
MPP3 membrane protein, palmitoylated 3 (MAGUK p55 subfamily member 3)
NCF2 neutrophil cytosolic factor 2
NDC80 NDC80 kinetochore complex component
NOTCH1 notch 1
OTUB2 OTU deubiquitinase, ubiquitin aldehyde binding 2
PAGR1 PAXIP1 associated glutamate-rich protein 1
PAK3 p21 protein (Cdc42/Rac)-activated kinase 3
PBLD phenazine biosynthesis-like protein domain containing
PLK1 polo-like kinase 1
POLDIP2 polymerase (DNA-directed), delta interacting protein 2
PRC1 protein regulator of cytokinesis 1
PRR3 proline rich 3
PSRC1 proline/serine-rich coiled-coil 1
RAB11FIP3 RAB11 family interacting protein 3 (class II)
RHOB ras homolog family member B
SCARA3 scavenger receptor class A, member 3
SCML2 sex comb on midleg-like 2 (Drosophila)
SETBP1 SET binding protein 1
SLC29A2 solute carrier family 29 (equilibrative nucleoside transporter), member 2
SLC29A3 solute carrier family 29 (equilibrative nucleoside transporter), member 3
SLITRK5 SLIT and NTRK-like family, member 5
SPC25 SPC25, NDC80 kinetochore complex component
SRSF3 serine/arginine-rich splicing factor 3
ST6GALNAC5 ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 5
TAGLN transgelin
TBC1D31 TBC1 domain family, member 31
TGFBI transforming growth factor, beta-induced, 68kDa
TINF2 TERF1 (TRF1)-interacting nuclear factor 2
TPX2 TPX2, microtubule-associated
TUBA3C tubulin, alpha 3c
USP27X ubiquitin specific peptidase 27, X-linked
WDR4 WD repeat domain 4
ZBTB44 zinc finger and BTB domain containing 44
ZNF165 zinc finger protein 165
ZNF180 zinc finger protein 180
ZXDC ZXD family zinc finger C