0173570-0000-7391 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

199 genes differentially expressed following the 0173570-0000-7391 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
AAK1 AP2 associated kinase 1
ACADSB acyl-CoA dehydrogenase, short/branched chain
ARHGEF9 Cdc42 guanine nucleotide exchange factor (GEF) 9
ASIC1 acid sensing (proton gated) ion channel 1
ATP2C2 ATPase, Ca++ transporting, type 2C, member 2
C14ORF105 chromosome 14 open reading frame 105
CACYBP calcyclin binding protein
CCNT2 cyclin T2
CDC14B cell division cycle 14B
CDKN1C cyclin-dependent kinase inhibitor 1C (p57, Kip2)
CEP131 centrosomal protein 131kDa
CHAC1 ChaC glutathione-specific gamma-glutamylcyclotransferase 1
CNNM2 cyclin and CBS domain divalent metal cation transport mediator 2
CSF1R colony stimulating factor 1 receptor
CTNND2 catenin (cadherin-associated protein), delta 2
CXCL5 chemokine (C-X-C motif) ligand 5
CYLC1 cylicin, basic protein of sperm head cytoskeleton 1
CYP2D6 cytochrome P450, family 2, subfamily D, polypeptide 6
DDIT3 DNA-damage-inducible transcript 3
DENND4A DENN/MADD domain containing 4A
DIMT1 DIM1 dimethyladenosine transferase 1 homolog (S. cerevisiae)
DLGAP4 discs, large (Drosophila) homolog-associated protein 4
DMBT1 deleted in malignant brain tumors 1
DNAJB9 DnaJ (Hsp40) homolog, subfamily B, member 9
DOCK5 dedicator of cytokinesis 5
DUSP1 dual specificity phosphatase 1
EGLN3 egl-9 family hypoxia-inducible factor 3
ERAP2 endoplasmic reticulum aminopeptidase 2
ETV1 ets variant 1
ETV5 ets variant 5
EVI5 ecotropic viral integration site 5
FAM134B family with sequence similarity 134, member B
FASTKD2 FAST kinase domains 2
FBXW7 F-box and WD repeat domain containing 7, E3 ubiquitin protein ligase
FCGR2B Fc fragment of IgG, low affinity IIb, receptor (CD32)
FEZ2 fasciculation and elongation protein zeta 2 (zygin II)
FLJ11292
GAS7 growth arrest-specific 7
GATA3 GATA binding protein 3
GFER growth factor, augmenter of liver regeneration
GPR137 G protein-coupled receptor 137
GPR161 G protein-coupled receptor 161
GRM1 glutamate receptor, metabotropic 1
GSK3A glycogen synthase kinase 3 alpha
GSTA1 glutathione S-transferase alpha 1
GUK1 guanylate kinase 1
HERPUD1 homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1
HIST1H4A histone cluster 1, H4a
HSP90B1 heat shock protein 90kDa beta (Grp94), member 1
IGFALS insulin-like growth factor binding protein, acid labile subunit
ITPKA inositol-trisphosphate 3-kinase A
KDM6A lysine (K)-specific demethylase 6A
KLF6 Kruppel-like factor 6
LMF2 lipase maturation factor 2
LRRK1 leucine-rich repeat kinase 1
MARK4 MAP/microtubule affinity-regulating kinase 4
MCM3AP minichromosome maintenance complex component 3 associated protein
MED16 mediator complex subunit 16
MVP major vault protein
MYLK myosin light chain kinase
NAIP NLR family, apoptosis inhibitory protein
NCOR2 nuclear receptor corepressor 2
NF2 neurofibromin 2 (merlin)
OAS2 2'-5'-oligoadenylate synthetase 2, 69/71kDa
PASK PAS domain containing serine/threonine kinase
PER1 period circadian clock 1
PIAS4 protein inhibitor of activated STAT, 4
PTGIR prostaglandin I2 (prostacyclin) receptor (IP)
RERE arginine-glutamic acid dipeptide (RE) repeats
SAPCD1 suppressor APC domain containing 1
SC5D sterol-C5-desaturase
SCD stearoyl-CoA desaturase (delta-9-desaturase)
SEL1L sel-1 suppressor of lin-12-like (C. elegans)
SENP5 SUMO1/sentrin specific peptidase 5
SLC16A10 solute carrier family 16 (aromatic amino acid transporter), member 10
SLC1A7 solute carrier family 1 (glutamate transporter), member 7
SLC7A8 solute carrier family 7 (amino acid transporter light chain, L system), member 8
SMC1A structural maintenance of chromosomes 1A
SMEK1 SMEK homolog 1, suppressor of mek1 (Dictyostelium)
SNCA synuclein, alpha (non A4 component of amyloid precursor)
SPTAN1 spectrin, alpha, non-erythrocytic 1
SRC SRC proto-oncogene, non-receptor tyrosine kinase
SSBP3 single stranded DNA binding protein 3
STC1 stanniocalcin 1
TAOK1 TAO kinase 1
TEX40 testis expressed 40
TIMM8A translocase of inner mitochondrial membrane 8 homolog A (yeast)
TJAP1 tight junction associated protein 1 (peripheral)
TMEM104 transmembrane protein 104
TMPRSS4 transmembrane protease, serine 4
TNFRSF25 tumor necrosis factor receptor superfamily, member 25
UAP1L1 UDP-N-acetylglucosamine pyrophosphorylase 1 like 1
UGT2B15 UDP glucuronosyltransferase 2 family, polypeptide B15
VCX2 variable charge, X-linked 2
VIPR2 vasoactive intestinal peptide receptor 2
WDR25 WD repeat domain 25
ZBTB20 zinc finger and BTB domain containing 20
ZER1 zyg-11 related, cell cycle regulator
ZMIZ2 zinc finger, MIZ-type containing 2
ZNF276 zinc finger protein 276

decreased expression

Symbol Name
ACTG2 actin, gamma 2, smooth muscle, enteric
ACVR2B activin A receptor, type IIB
ADORA2B adenosine A2b receptor
ADRB2 adrenoceptor beta 2, surface
AHDC1 AT hook, DNA binding motif, containing 1
ARHGEF1 Rho guanine nucleotide exchange factor (GEF) 1
ARMC6 armadillo repeat containing 6
ASPSCR1 alveolar soft part sarcoma chromosome region, candidate 1
BCAS3 breast carcinoma amplified sequence 3
C16ORF59 chromosome 16 open reading frame 59
C1ORF159 chromosome 1 open reading frame 159
C9ORF3 chromosome 9 open reading frame 3
CAPN15 calpain 15
CCBL1 cysteine conjugate-beta lyase, cytoplasmic
CCRL2 chemokine (C-C motif) receptor-like 2
CDC37L1 cell division cycle 37-like 1
CDH3 cadherin 3, type 1, P-cadherin (placental)
CDH7 cadherin 7, type 2
CDK6 cyclin-dependent kinase 6
CDON cell adhesion associated, oncogene regulated
CHRNB1 cholinergic receptor, nicotinic, beta 1 (muscle)
CLEC10A C-type lectin domain family 10, member A
CLIP4 CAP-GLY domain containing linker protein family, member 4
CRYBB2P1 crystallin, beta B2 pseudogene 1
CTSD cathepsin D
CWF19L1 CWF19-like 1, cell cycle control (S. pombe)
CYP26B1 cytochrome P450, family 26, subfamily B, polypeptide 1
DDX31 DEAD (Asp-Glu-Ala-Asp) box polypeptide 31
DHRS11 dehydrogenase/reductase (SDR family) member 11
DNMBP dynamin binding protein
DPY19L2P2 DPY19L2 pseudogene 2
ECM1 extracellular matrix protein 1
EN2 engrailed homeobox 2
EVPL envoplakin
EYA4 EYA transcriptional coactivator and phosphatase 4
FAIM Fas apoptotic inhibitory molecule
FGD1 FYVE, RhoGEF and PH domain containing 1
FGD6 FYVE, RhoGEF and PH domain containing 6
FSD1 fibronectin type III and SPRY domain containing 1
GABPA GA binding protein transcription factor, alpha subunit 60kDa
GNAZ guanine nucleotide binding protein (G protein), alpha z polypeptide
GTF2I general transcription factor IIi
HIST1H2BJ histone cluster 1, H2bj
IGSF3 immunoglobulin superfamily, member 3
INF2 inverted formin, FH2 and WH2 domain containing
INPPL1 inositol polyphosphate phosphatase-like 1
KDM4D lysine (K)-specific demethylase 4D
KIAA0556 KIAA0556
KLF2 Kruppel-like factor 2
LMBR1L limb development membrane protein 1-like
LPAR6 lysophosphatidic acid receptor 6
LRRC61 leucine rich repeat containing 61
MAN2C1 mannosidase, alpha, class 2C, member 1
MANBA mannosidase, beta A, lysosomal
MICAL3 microtubule associated monooxygenase, calponin and LIM domain containing 3
MLYCD malonyl-CoA decarboxylase
MPP3 membrane protein, palmitoylated 3 (MAGUK p55 subfamily member 3)
MTMR11 myotubularin related protein 11
MUM1 melanoma associated antigen (mutated) 1
MYO1E myosin IE
NECAB3 N-terminal EF-hand calcium binding protein 3
NT5DC3 5'-nucleotidase domain containing 3
NT5M 5',3'-nucleotidase, mitochondrial
OPA3 optic atrophy 3 (autosomal recessive, with chorea and spastic paraplegia)
OPLAH 5-oxoprolinase (ATP-hydrolysing)
PGGT1B protein geranylgeranyltransferase type I, beta subunit
PIP5K1C phosphatidylinositol-4-phosphate 5-kinase, type I, gamma
PLCD1 phospholipase C, delta 1
PLEKHM2 pleckstrin homology domain containing, family M (with RUN domain) member 2
PRKCD protein kinase C, delta
PRKX protein kinase, X-linked
PRMT7 protein arginine methyltransferase 7
RPL23AP32 ribosomal protein L23a pseudogene 32
RPUSD2 RNA pseudouridylate synthase domain containing 2
SAMD9 sterile alpha motif domain containing 9
SELENBP1 selenium binding protein 1
SETBP1 SET binding protein 1
SETD6 SET domain containing 6
SIGLEC15 sialic acid binding Ig-like lectin 15
SIPA1 signal-induced proliferation-associated 1
SLITRK5 SLIT and NTRK-like family, member 5
SPATA2L spermatogenesis associated 2-like
SPEG SPEG complex locus
STAG3 stromal antigen 3
TBL1XR1 transducin (beta)-like 1 X-linked receptor 1
TEP1 telomerase-associated protein 1
TLR2 toll-like receptor 2
TMEM186 transmembrane protein 186
TMEM8B transmembrane protein 8B
TMOD3 tropomodulin 3 (ubiquitous)
TRAPPC2 trafficking protein particle complex 2
TSC22D4 TSC22 domain family, member 4
USP18 ubiquitin specific peptidase 18
USP27X ubiquitin specific peptidase 27, X-linked
WDR19 WD repeat domain 19
WDR4 WD repeat domain 4
ZNF552 zinc finger protein 552
ZNF675 zinc finger protein 675
ZNHIT2 zinc finger, HIT-type containing 2