0175029-0000-3691 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

199 genes differentially expressed following the 0175029-0000-3691 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ACO2 aconitase 2, mitochondrial
ACPP acid phosphatase, prostate
ADAM5 ADAM metallopeptidase domain 5 (pseudogene)
ADAMTS5 ADAM metallopeptidase with thrombospondin type 1 motif, 5
ADGRV1 adhesion G protein-coupled receptor V1
ADRBK2 adrenergic, beta, receptor kinase 2
ALDOB aldolase B, fructose-bisphosphate
APOL2 apolipoprotein L, 2
ARG1 arginase 1
ARMC4 armadillo repeat containing 4
ARSA arylsulfatase A
ATN1 atrophin 1
ATP10B ATPase, class V, type 10B
BMP7 bone morphogenetic protein 7
CCKAR cholecystokinin A receptor
CD1A CD1a molecule
CD200 CD200 molecule
CD86 CD86 molecule
CHI3L2 chitinase 3-like 2
CHN2 chimerin 2
CHRM4 cholinergic receptor, muscarinic 4
CHRNA2 cholinergic receptor, nicotinic, alpha 2 (neuronal)
CIDEB cell death-inducing DFFA-like effector b
CIITA class II, major histocompatibility complex, transactivator
CLDN18 claudin 18
CNGB3 cyclic nucleotide gated channel beta 3
CNTD2 cyclin N-terminal domain containing 2
COL1A1 collagen, type I, alpha 1
CRTC1 CREB regulated transcription coactivator 1
DRD2 dopamine receptor D2
FCGR2C Fc fragment of IgG, low affinity IIc, receptor for (CD32) (gene/pseudogene)
FGFR3 fibroblast growth factor receptor 3
FSCN3 fascin actin-bundling protein 3, testicular
FXYD7 FXYD domain containing ion transport regulator 7
GAB1 GRB2-associated binding protein 1
GGT1 gamma-glutamyltransferase 1
GRIA4 glutamate receptor, ionotropic, AMPA 4
HPS1 Hermansky-Pudlak syndrome 1
IGLL1 immunoglobulin lambda-like polypeptide 1
ITGA7 integrin, alpha 7
JRK Jrk homolog (mouse)
KCNJ15 potassium channel, inwardly rectifying subfamily J, member 15
KEL Kell blood group, metallo-endopeptidase
KIAA0368 KIAA0368
KIR2DL5A killer cell immunoglobulin-like receptor, two domains, long cytoplasmic tail, 5A
KRT33A keratin 33A, type I
LECT1 leukocyte cell derived chemotaxin 1
LEPR leptin receptor
LOC100131510 uncharacterized LOC100131510
LRRN3 leucine rich repeat neuronal 3
LYRM9 LYR motif containing 9
MAP7D3 MAP7 domain containing 3
MFSD7 major facilitator superfamily domain containing 7
MUC3B mucin 3B, cell surface associated
NECAB2 N-terminal EF-hand calcium binding protein 2
NFKB2 nuclear factor of kappa light polypeptide gene enhancer in B-cells 2 (p49/p100)
NR4A1 nuclear receptor subfamily 4, group A, member 1
NRIP3 nuclear receptor interacting protein 3
PART1 prostate androgen-regulated transcript 1 (non-protein coding)
PCDHGA10 protocadherin gamma subfamily A, 10
PDE2A phosphodiesterase 2A, cGMP-stimulated
PHOX2B paired-like homeobox 2b
PLA2G1B phospholipase A2, group IB (pancreas)
PPBP pro-platelet basic protein (chemokine (C-X-C motif) ligand 7)
PPIL2 peptidylprolyl isomerase (cyclophilin)-like 2
PTGDS prostaglandin D2 synthase 21kDa (brain)
RDH8 retinol dehydrogenase 8 (all-trans)
RERE arginine-glutamic acid dipeptide (RE) repeats
RIMS3 regulating synaptic membrane exocytosis 3
RNASE1 ribonuclease, RNase A family, 1 (pancreatic)
RPL10L ribosomal protein L10-like
RRP12 ribosomal RNA processing 12 homolog (S. cerevisiae)
RYR1 ryanodine receptor 1 (skeletal)
SC5D sterol-C5-desaturase
SCN10A sodium channel, voltage gated, type X alpha subunit
SDHD succinate dehydrogenase complex, subunit D, integral membrane protein
SH3BP1 SH3-domain binding protein 1
SIGLEC7 sialic acid binding Ig-like lectin 7
SLC16A5 solute carrier family 16 (monocarboxylate transporter), member 5
SLC25A30 solute carrier family 25, member 30
SMG7-AS1 SMG7 antisense RNA 1
SNAI1 snail family zinc finger 1
SNTB1 syntrophin, beta 1 (dystrophin-associated protein A1, 59kDa, basic component 1)
SPO11 SPO11 meiotic protein covalently bound to DSB
SSX1 synovial sarcoma, X breakpoint 1
STAT2 signal transducer and activator of transcription 2, 113kDa
SYT5 synaptotagmin V
TBCD tubulin folding cofactor D
TBX5 T-box 5
TESC tescalcin
THRB thyroid hormone receptor, beta
TM6SF2 transmembrane 6 superfamily member 2
TNFRSF4 tumor necrosis factor receptor superfamily, member 4
TNFRSF9 tumor necrosis factor receptor superfamily, member 9
TNS1 tensin 1
TPSAB1 tryptase alpha/beta 1
TRD T cell receptor delta locus
VCL vinculin
WDR59 WD repeat domain 59

decreased expression

Symbol Name
AAR2 AAR2 splicing factor homolog (S. cerevisiae)
ADM adrenomedullin
ADRB2 adrenoceptor beta 2, surface
ARF6 ADP-ribosylation factor 6
ASAP1-IT1 ASAP1 intronic transcript 1
BCAR3 breast cancer anti-estrogen resistance 3
BRIX1 BRX1, biogenesis of ribosomes
BYSL bystin-like
C14ORF169 chromosome 14 open reading frame 169
CDCA4 cell division cycle associated 4
CDR2 cerebellar degeneration-related protein 2, 62kDa
CENPC centromere protein C
CHD1 chromodomain helicase DNA binding protein 1
CLP1 cleavage and polyadenylation factor I subunit 1
COA7 cytochrome c oxidase assembly factor 7 (putative)
CYR61 cysteine-rich, angiogenic inducer, 61
DKK1 dickkopf WNT signaling pathway inhibitor 1
DNAAF2 dynein, axonemal, assembly factor 2
DNAJB1 DnaJ (Hsp40) homolog, subfamily B, member 1
DUSP11 dual specificity phosphatase 11 (RNA/RNP complex 1-interacting)
DUSP6 dual specificity phosphatase 6
E2F6 E2F transcription factor 6
EIF2AK3 eukaryotic translation initiation factor 2-alpha kinase 3
ERCC6L excision repair cross-complementation group 6-like
FADD Fas (TNFRSF6)-associated via death domain
FAM53C family with sequence similarity 53, member C
FASTKD5 FAST kinase domains 5
FBXO5 F-box protein 5
FOSL1 FOS-like antigen 1
GEMIN4 gem (nuclear organelle) associated protein 4
GPR87 G protein-coupled receptor 87
GTF2B general transcription factor IIB
HAS2 hyaluronan synthase 2
HAUS3 HAUS augmin-like complex, subunit 3
HJURP Holliday junction recognition protein
HSPA1A heat shock 70kDa protein 1A
IER5 immediate early response 5
IP6K2 inositol hexakisphosphate kinase 2
JMJD1C jumonji domain containing 1C
KIAA0232 KIAA0232
KLHL21 kelch-like family member 21
LEMD3 LEM domain containing 3
MAD2L1BP MAD2L1 binding protein
MED17 mediator complex subunit 17
MGA MGA, MAX dimerization protein
MORC3 MORC family CW-type zinc finger 3
MPHOSPH10 M-phase phosphoprotein 10 (U3 small nucleolar ribonucleoprotein)
NDC80 NDC80 kinetochore complex component
NDST2 N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 2
NFE2L2 nuclear factor, erythroid 2-like 2
NKRF NFKB repressing factor
NRBF2 nuclear receptor binding factor 2
NXT1 nuclear transport factor 2-like export factor 1
PCF11 PCF11 cleavage and polyadenylation factor subunit
PLEKHF2 pleckstrin homology domain containing, family F (with FYVE domain) member 2
PNRC2 proline-rich nuclear receptor coactivator 2
PPP1R10 protein phosphatase 1, regulatory subunit 10
PTRH2 peptidyl-tRNA hydrolase 2
RANBP6 RAN binding protein 6
RBM7 RNA binding motif protein 7
RDH14 retinol dehydrogenase 14 (all-trans/9-cis/11-cis)
RGS2 regulator of G-protein signaling 2
RIOK2 RIO kinase 2
RNF113A ring finger protein 113A
RNF139 ring finger protein 139
RNF219 ring finger protein 219
RNMTL1 RNA methyltransferase like 1
RPP38 ribonuclease P/MRP 38kDa subunit
RSBN1 round spermatid basic protein 1
SCO2 SCO2 cytochrome c oxidase assembly protein
SLC38A2 solute carrier family 38, member 2
SMG8 SMG8 nonsense mediated mRNA decay factor
SOX9 SRY (sex determining region Y)-box 9
SUV420H1 suppressor of variegation 4-20 homolog 1 (Drosophila)
TAF5 TAF5 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 100kDa
TBCC tubulin folding cofactor C
TBX3 T-box 3
TEFM transcription elongation factor, mitochondrial
TOB1 transducer of ERBB2, 1
TRIB1 tribbles pseudokinase 1
TRIM32 tripartite motif containing 32
TRMT12 tRNA methyltransferase 12 homolog (S. cerevisiae)
URB2 URB2 ribosome biogenesis 2 homolog (S. cerevisiae)
UTP3 UTP3, small subunit (SSU) processome component, homolog (S. cerevisiae)
VANGL1 VANGL planar cell polarity protein 1
VCPKMT valosin containing protein lysine (K) methyltransferase
YRDC yrdC N(6)-threonylcarbamoyltransferase domain containing
ZBED5 zinc finger, BED-type containing 5
ZBTB24 zinc finger and BTB domain containing 24
ZC3H4 zinc finger CCCH-type containing 4
ZCCHC10 zinc finger, CCHC domain containing 10
ZCCHC8 zinc finger, CCHC domain containing 8
ZNF165 zinc finger protein 165
ZNF175 zinc finger protein 175
ZNF184 zinc finger protein 184
ZNF217 zinc finger protein 217
ZNF329 zinc finger protein 329
ZNF443 zinc finger protein 443
ZNF586 zinc finger protein 586
ZNF7 zinc finger protein 7