0175029-0000-4713 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

199 genes differentially expressed following the 0175029-0000-4713 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
A2M alpha-2-macroglobulin
ACAA2 acetyl-CoA acyltransferase 2
ACTG2 actin, gamma 2, smooth muscle, enteric
ACTL8 actin-like 8
ADAM15 ADAM metallopeptidase domain 15
AKR1C1 aldo-keto reductase family 1, member C1
ALOX15 arachidonate 15-lipoxygenase
AQP3 aquaporin 3 (Gill blood group)
ASPH aspartate beta-hydroxylase
CD24 CD24 molecule
CDH11 cadherin 11, type 2, OB-cadherin (osteoblast)
CDK18 cyclin-dependent kinase 18
CHRNA3 cholinergic receptor, nicotinic, alpha 3 (neuronal)
CHST8 carbohydrate (N-acetylgalactosamine 4-0) sulfotransferase 8
CLSTN2 calsyntenin 2
CNN2 calponin 2
CRABP1 cellular retinoic acid binding protein 1
CTSF cathepsin F
DBT dihydrolipoamide branched chain transacylase E2
DCBLD2 discoidin, CUB and LCCL domain containing 2
DGAT1 diacylglycerol O-acyltransferase 1
DIRAS3 DIRAS family, GTP-binding RAS-like 3
DNASE2 deoxyribonuclease II, lysosomal
DRD2 dopamine receptor D2
EGR1 early growth response 1
EIF2S3 eukaryotic translation initiation factor 2, subunit 3 gamma, 52kDa
EMC1 ER membrane protein complex subunit 1
FOXN3 forkhead box N3
G6PC3 glucose 6 phosphatase, catalytic, 3
GALC galactosylceramidase
GAST gastrin
GID4 GID complex subunit 4
GINS4 GINS complex subunit 4 (Sld5 homolog)
GLRX3 glutaredoxin 3
GM2A GM2 ganglioside activator
GNAQ guanine nucleotide binding protein (G protein), q polypeptide
GNL3L guanine nucleotide binding protein-like 3 (nucleolar)-like
GRIP2 glutamate receptor interacting protein 2
GSPT1 G1 to S phase transition 1
GULP1 GULP, engulfment adaptor PTB domain containing 1
HFE hemochromatosis
HIST1H2AE histone cluster 1, H2ae
HIST1H2AI histone cluster 1, H2ai
HIST1H2BG histone cluster 1, H2bg
HIST1H3J histone cluster 1, H3j
HOXB2 homeobox B2
HUWE1 HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase
IDS iduronate 2-sulfatase
IDUA iduronidase, alpha-L-
IFI6 interferon, alpha-inducible protein 6
IL11 interleukin 11
IL6ST interleukin 6 signal transducer
KIAA1549L KIAA1549-like
KMO kynurenine 3-monooxygenase (kynurenine 3-hydroxylase)
KRT17 keratin 17, type I
KRT7 keratin 7, type II
LAMP1 lysosomal-associated membrane protein 1
LGALS9 lectin, galactoside-binding, soluble, 9
LOC100286895 cell division cycle 27 homolog pseudogene
LTBP4 latent transforming growth factor beta binding protein 4
MADCAM1 mucosal vascular addressin cell adhesion molecule 1
MALL mal, T-cell differentiation protein-like
MAP1B microtubule-associated protein 1B
MAPK11 mitogen-activated protein kinase 11
MDM2 MDM2 proto-oncogene, E3 ubiquitin protein ligase
MLLT4 myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 4
MMP16 matrix metallopeptidase 16 (membrane-inserted)
MSMB microseminoprotein, beta-
ONECUT2 one cut homeobox 2
PAX5 paired box 5
PICK1 protein interacting with PRKCA 1
PLAC1 placenta-specific 1
PRDX2 peroxiredoxin 2
PROZ protein Z, vitamin K-dependent plasma glycoprotein
QKI QKI, KH domain containing, RNA binding
RAB6A RAB6A, member RAS oncogene family
RBBP9 retinoblastoma binding protein 9
RPL23 ribosomal protein L23
RPS2 ribosomal protein S2
S100A11 S100 calcium binding protein A11
SAPCD1 suppressor APC domain containing 1
SCRN3 secernin 3
SH3BGRL SH3 domain binding glutamate-rich protein like
SH3GL3 SH3-domain GRB2-like 3
SLC17A2 solute carrier family 17, member 2
SLC25A23 solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 23
SMARCD3 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 3
SNAP23 synaptosomal-associated protein, 23kDa
SSX1 synovial sarcoma, X breakpoint 1
STX10 syntaxin 10
SYNJ2 synaptojanin 2
TAF9B TAF9B RNA polymerase II, TATA box binding protein (TBP)-associated factor, 31kDa
TCF3 transcription factor 3
TFPI2 tissue factor pathway inhibitor 2
TGOLN2 trans-golgi network protein 2
TMPRSS4 transmembrane protease, serine 4
TNFRSF25 tumor necrosis factor receptor superfamily, member 25
VWA5A von Willebrand factor A domain containing 5A
WIPF1 WAS/WASL interacting protein family, member 1

decreased expression

Symbol Name
ADNP activity-dependent neuroprotector homeobox
AMIGO2 adhesion molecule with Ig-like domain 2
AMOTL2 angiomotin like 2
ANKRD49 ankyrin repeat domain 49
BAMBI BMP and activin membrane-bound inhibitor
BYSL bystin-like
C14ORF169 chromosome 14 open reading frame 169
CCNL1 cyclin L1
CDCA4 cell division cycle associated 4
CDKN1B cyclin-dependent kinase inhibitor 1B (p27, Kip1)
CDR2 cerebellar degeneration-related protein 2, 62kDa
CEBPB CCAAT/enhancer binding protein (C/EBP), beta
CHD1 chromodomain helicase DNA binding protein 1
CLP1 cleavage and polyadenylation factor I subunit 1
CSRNP2 cysteine-serine-rich nuclear protein 2
CSTF1 cleavage stimulation factor, 3' pre-RNA, subunit 1, 50kDa
DCLRE1B DNA cross-link repair 1B
DKK1 dickkopf WNT signaling pathway inhibitor 1
DNAAF2 dynein, axonemal, assembly factor 2
DNAJB1 DnaJ (Hsp40) homolog, subfamily B, member 1
DOLK dolichol kinase
E2F6 E2F transcription factor 6
EFNA1 ephrin-A1
ERCC6L excision repair cross-complementation group 6-like
FADD Fas (TNFRSF6)-associated via death domain
FAM46A family with sequence similarity 46, member A
FBXL14 F-box and leucine-rich repeat protein 14
FBXO5 F-box protein 5
FOXA1 forkhead box A1
GCC1 GRIP and coiled-coil domain containing 1
GTF2B general transcription factor IIB
HILPDA hypoxia inducible lipid droplet-associated
HJURP Holliday junction recognition protein
ID1 inhibitor of DNA binding 1, dominant negative helix-loop-helix protein
ID3 inhibitor of DNA binding 3, dominant negative helix-loop-helix protein
IER5 immediate early response 5
ING3 inhibitor of growth family, member 3
IRS1 insulin receptor substrate 1
IRX5 iroquois homeobox 5
KBTBD2 kelch repeat and BTB (POZ) domain containing 2
KLF10 Kruppel-like factor 10
LEMD3 LEM domain containing 3
MAD2L1BP MAD2L1 binding protein
METTL18 methyltransferase like 18
MFSD5 major facilitator superfamily domain containing 5
MPHOSPH10 M-phase phosphoprotein 10 (U3 small nucleolar ribonucleoprotein)
NDC80 NDC80 kinetochore complex component
NFE2L2 nuclear factor, erythroid 2-like 2
NXT1 nuclear transport factor 2-like export factor 1
OSR2 odd-skipped related transciption factor 2
OXSM 3-oxoacyl-ACP synthase, mitochondrial
PLEKHF2 pleckstrin homology domain containing, family F (with FYVE domain) member 2
PLK2 polo-like kinase 2
PPM1D protein phosphatase, Mg2+/Mn2+ dependent, 1D
PPP1R10 protein phosphatase 1, regulatory subunit 10
PPRC1 peroxisome proliferator-activated receptor gamma, coactivator-related 1
PTCD1 pentatricopeptide repeat domain 1
PTRH2 peptidyl-tRNA hydrolase 2
RANBP6 RAN binding protein 6
RDH14 retinol dehydrogenase 14 (all-trans/9-cis/11-cis)
RHOB ras homolog family member B
RIOK2 RIO kinase 2
RND3 Rho family GTPase 3
RNF111 ring finger protein 111
RNF113A ring finger protein 113A
RNF139 ring finger protein 139
RNMTL1 RNA methyltransferase like 1
RPP38 ribonuclease P/MRP 38kDa subunit
RSBN1 round spermatid basic protein 1
SERTAD3 SERTA domain containing 3
SIRT1 sirtuin 1
SLC30A1 solute carrier family 30 (zinc transporter), member 1
SLC38A2 solute carrier family 38, member 2
SMG8 SMG8 nonsense mediated mRNA decay factor
SPATA2 spermatogenesis associated 2
SPATA2L spermatogenesis associated 2-like
SUV420H1 suppressor of variegation 4-20 homolog 1 (Drosophila)
TAF7 TAF7 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 55kDa
TBCC tubulin folding cofactor C
TBK1 TANK-binding kinase 1
TGIF1 TGFB-induced factor homeobox 1
TIPARP TCDD-inducible poly(ADP-ribose) polymerase
TNFRSF1A tumor necrosis factor receptor superfamily, member 1A
TOB1 transducer of ERBB2, 1
TOB2 transducer of ERBB2, 2
TRIB1 tribbles pseudokinase 1
TRIM32 tripartite motif containing 32
TRMT12 tRNA methyltransferase 12 homolog (S. cerevisiae)
TSC22D1 TSC22 domain family, member 1
TSKU tsukushi, small leucine rich proteoglycan
TTI2 TELO2 interacting protein 2
USPL1 ubiquitin specific peptidase like 1
UTP3 UTP3, small subunit (SSU) processome component, homolog (S. cerevisiae)
YRDC yrdC N(6)-threonylcarbamoyltransferase domain containing
ZBED5 zinc finger, BED-type containing 5
ZBTB24 zinc finger and BTB domain containing 24
ZNF217 zinc finger protein 217
ZNF263 zinc finger protein 263
ZNF274 zinc finger protein 274
ZNF443 zinc finger protein 443