0179445-0000-3630 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

198 genes differentially expressed following the 0179445-0000-3630 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ABCF2 ATP-binding cassette, sub-family F (GCN20), member 2
ACACA acetyl-CoA carboxylase alpha
ADAMTS7 ADAM metallopeptidase with thrombospondin type 1 motif, 7
ARHGAP25 Rho GTPase activating protein 25
ASB7 ankyrin repeat and SOCS box containing 7
ATF3 activating transcription factor 3
ATP5C1 ATP synthase, H+ transporting, mitochondrial F1 complex, gamma polypeptide 1
ATXN2L ataxin 2-like
ATXN7L1 ataxin 7-like 1
BCL2L11 BCL2-like 11 (apoptosis facilitator)
BHLHE40 basic helix-loop-helix family, member e40
BRF1 BRF1, RNA polymerase III transcription initiation factor 90 kDa subunit
CACNA2D1 calcium channel, voltage-dependent, alpha 2/delta subunit 1
CALML3 calmodulin-like 3
CCDC88C coiled-coil domain containing 88C
CCL18 chemokine (C-C motif) ligand 18 (pulmonary and activation-regulated)
CD200 CD200 molecule
CLDN1 claudin 1
CNOT4 CCR4-NOT transcription complex, subunit 4
CSNK1G1 casein kinase 1, gamma 1
CYP1A1 cytochrome P450, family 1, subfamily A, polypeptide 1
CYP1B1 cytochrome P450, family 1, subfamily B, polypeptide 1
DDN dendrin
DICER1 dicer 1, ribonuclease type III
DLK2 delta-like 2 homolog (Drosophila)
EDRF1 erythroid differentiation regulatory factor 1
EGR1 early growth response 1
ERP44 endoplasmic reticulum protein 44
FAM120C family with sequence similarity 120C
FBXW4P1 F-box and WD repeat domain containing 4 pseudogene 1
FBXW7 F-box and WD repeat domain containing 7, E3 ubiquitin protein ligase
FEM1B fem-1 homolog b (C. elegans)
FOSL1 FOS-like antigen 1
FOSL2 FOS-like antigen 2
FUBP1 far upstream element (FUSE) binding protein 1
GADD45A growth arrest and DNA-damage-inducible, alpha
GOLGA4 golgin A4
GPR107 G protein-coupled receptor 107
GPR87 G protein-coupled receptor 87
HBS1L HBS1-like translational GTPase
HIST1H2BO histone cluster 1, H2bo
HR hair growth associated
IFI6 interferon, alpha-inducible protein 6
IP6K2 inositol hexakisphosphate kinase 2
ITGB1 integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12)
KLF6 Kruppel-like factor 6
KLHL20 kelch-like family member 20
KLHL28 kelch-like family member 28
KRT37 keratin 37, type I
LIF leukemia inhibitory factor
LINS lines homolog (Drosophila)
LMTK2 lemur tyrosine kinase 2
LOC157562 uncharacterized LOC157562
MAFF v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog F
MDM2 MDM2 proto-oncogene, E3 ubiquitin protein ligase
MIR22HG MIR22 host gene
MKL1 megakaryoblastic leukemia (translocation) 1
MKRN3 makorin ring finger protein 3
MYO1B myosin IB
NEDD9 neural precursor cell expressed, developmentally down-regulated 9
NELL2 NEL-like 2 (chicken)
NFIB nuclear factor I/B
NFYA nuclear transcription factor Y, alpha
NOX1 NADPH oxidase 1
NR4A1 nuclear receptor subfamily 4, group A, member 1
NUP160 nucleoporin 160kDa
PARD6B par-6 family cell polarity regulator beta
PGAP1 post-GPI attachment to proteins 1
PIGR polymeric immunoglobulin receptor
PMAIP1 phorbol-12-myristate-13-acetate-induced protein 1
PPP2R5C protein phosphatase 2, regulatory subunit B', gamma
PRKCQ protein kinase C, theta
PSMD11 proteasome (prosome, macropain) 26S subunit, non-ATPase, 11
REEP2 receptor accessory protein 2
RERE arginine-glutamic acid dipeptide (RE) repeats
SENP6 SUMO1/sentrin specific peptidase 6
SERPINB5 serpin peptidase inhibitor, clade B (ovalbumin), member 5
SESN1 sestrin 1
SFPQ splicing factor proline/glutamine-rich
SLC39A9 solute carrier family 39, member 9
SMEK1 SMEK homolog 1, suppressor of mek1 (Dictyostelium)
SMYD2 SET and MYND domain containing 2
SRCAP Snf2-related CREBBP activator protein
SUSD6 sushi domain containing 6
TICAM1 toll-like receptor adaptor molecule 1
TMEM183A transmembrane protein 183A
TNXB tenascin XB
TRIM29 tripartite motif containing 29
TSC22D2 TSC22 domain family, member 2
TXNIP thioredoxin interacting protein
URB1 URB1 ribosome biogenesis 1 homolog (S. cerevisiae)
VCAN versican
VEGFA vascular endothelial growth factor A
ZBTB17 zinc finger and BTB domain containing 17
ZFX zinc finger protein, X-linked
ZMAT3 zinc finger, matrin-type 3
ZMYM5 zinc finger, MYM-type 5
ZNF750 zinc finger protein 750
ZXDB zinc finger, X-linked, duplicated B

decreased expression

Symbol Name
AGO2 argonaute RISC catalytic component 2
ARID5B AT rich interactive domain 5B (MRF1-like)
ARMC7 armadillo repeat containing 7
ARMCX5 armadillo repeat containing, X-linked 5
ASPM asp (abnormal spindle) homolog, microcephaly associated (Drosophila)
ASXL2 additional sex combs like transcriptional regulator 2
AXIN1 axin 1
BANP BTG3 associated nuclear protein
BRIP1 BRCA1 interacting protein C-terminal helicase 1
C14ORF169 chromosome 14 open reading frame 169
C7ORF49 chromosome 7 open reading frame 49
CASP8AP2 caspase 8 associated protein 2
CBFA2T3 core-binding factor, runt domain, alpha subunit 2; translocated to, 3
CCNE2 cyclin E2
CEBPA CCAAT/enhancer binding protein (C/EBP), alpha
CHMP6 charged multivesicular body protein 6
CHST12 carbohydrate (chondroitin 4) sulfotransferase 12
CHST15 carbohydrate (N-acetylgalactosamine 4-sulfate 6-O) sulfotransferase 15
CSRNP2 cysteine-serine-rich nuclear protein 2
CSTF3 cleavage stimulation factor, 3' pre-RNA, subunit 3, 77kDa
DDX31 DEAD (Asp-Glu-Ala-Asp) box polypeptide 31
DIP2C DIP2 disco-interacting protein 2 homolog C (Drosophila)
DNA2 DNA replication helicase/nuclease 2
DNAAF2 dynein, axonemal, assembly factor 2
DOLK dolichol kinase
DSE dermatan sulfate epimerase
E2F8 E2F transcription factor 8
EFNA4 ephrin-A4
ELOVL4 ELOVL fatty acid elongase 4
FADD Fas (TNFRSF6)-associated via death domain
FANCF Fanconi anemia, complementation group F
FOXK2 forkhead box K2
FRAT2 frequently rearranged in advanced T-cell lymphomas 2
GLCE glucuronic acid epimerase
GOLPH3 golgi phosphoprotein 3 (coat-protein)
GPR19 G protein-coupled receptor 19
GRHL2 grainyhead-like 2 (Drosophila)
HSPA2 heat shock 70kDa protein 2
HSPBAP1 HSPB (heat shock 27kDa) associated protein 1
KIAA0513 KIAA0513
KIF11 kinesin family member 11
KIF14 kinesin family member 14
KIF16B kinesin family member 16B
KLHL26 kelch-like family member 26
KRCC1 lysine-rich coiled-coil 1
MAMLD1 mastermind-like domain containing 1
MAVS mitochondrial antiviral signaling protein
MCM9 minichromosome maintenance complex component 9
MEPCE methylphosphate capping enzyme
METTL1 methyltransferase like 1
METTL18 methyltransferase like 18
METTL4 methyltransferase like 4
MTCL1 microtubule crosslinking factor 1
MTRF1 mitochondrial translational release factor 1
NACC2 NACC family member 2, BEN and BTB (POZ) domain containing
NDC80 NDC80 kinetochore complex component
NDST2 N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 2
PLEKHA5 pleckstrin homology domain containing, family A member 5
PPAN peter pan homolog (Drosophila)
PPP1R10 protein phosphatase 1, regulatory subunit 10
PRR15L proline rich 15-like
PRR3 proline rich 3
PUS7L pseudouridylate synthase 7 homolog (S. cerevisiae)-like
RAB20 RAB20, member RAS oncogene family
RBL1 retinoblastoma-like 1
RBM15B RNA binding motif protein 15B
RFWD3 ring finger and WD repeat domain 3
RPP38 ribonuclease P/MRP 38kDa subunit
RWDD2A RWD domain containing 2A
S100PBP S100P binding protein
SETD1B SET domain containing 1B
SETX senataxin
STARD13 StAR-related lipid transfer (START) domain containing 13
SUOX sulfite oxidase
SUV420H1 suppressor of variegation 4-20 homolog 1 (Drosophila)
SYNRG synergin, gamma
TACC2 transforming, acidic coiled-coil containing protein 2
TAF1B TATA box binding protein (TBP)-associated factor, RNA polymerase I, B, 63kDa
TAF5 TAF5 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 100kDa
TBC1D31 TBC1 domain family, member 31
TMEM185B transmembrane protein 185B
TMEM186 transmembrane protein 186
TRMT12 tRNA methyltransferase 12 homolog (S. cerevisiae)
TULP4 tubby like protein 4
UTP14C UTP14, U3 small nucleolar ribonucleoprotein, homolog C (yeast)
VANGL1 VANGL planar cell polarity protein 1
WBP1L WW domain binding protein 1-like
WDR5B WD repeat domain 5B
ZBED5 zinc finger, BED-type containing 5
ZBED8 zinc finger, BED-type containing 8
ZBTB3 zinc finger and BTB domain containing 3
ZC3H4 zinc finger CCCH-type containing 4
ZCCHC2 zinc finger, CCHC domain containing 2
ZCCHC6 zinc finger, CCHC domain containing 6
ZIC1 Zic family member 1
ZMYM1 zinc finger, MYM-type 1
ZNF165 zinc finger protein 165
ZNF232 zinc finger protein 232
ZSCAN5A zinc finger and SCAN domain containing 5A