0179445-0000-3733 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

200 genes differentially expressed following the 0179445-0000-3733 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ABL2 ABL proto-oncogene 2, non-receptor tyrosine kinase
AMACR alpha-methylacyl-CoA racemase
ANKRD55 ankyrin repeat domain 55
ANTXR1 anthrax toxin receptor 1
ARC activity-regulated cytoskeleton-associated protein
ASPH aspartate beta-hydroxylase
ASPHD1 aspartate beta-hydroxylase domain containing 1
BMP4 bone morphogenetic protein 4
BMP7 bone morphogenetic protein 7
CCDC88C coiled-coil domain containing 88C
CD5 CD5 molecule
CD52 CD52 molecule
CD86 CD86 molecule
CHI3L2 chitinase 3-like 2
CNGB3 cyclic nucleotide gated channel beta 3
CNTD2 cyclin N-terminal domain containing 2
COBLL1 cordon-bleu WH2 repeat protein-like 1
CTSS cathepsin S
CYP1B1 cytochrome P450, family 1, subfamily B, polypeptide 1
DCLK2 doublecortin-like kinase 2
DDIT4 DNA-damage-inducible transcript 4
DHRS9 dehydrogenase/reductase (SDR family) member 9
DIDO1 death inducer-obliterator 1
DNAH17 dynein, axonemal, heavy chain 17
DTX3 deltex 3, E3 ubiquitin ligase
EDRF1 erythroid differentiation regulatory factor 1
EFNB3 ephrin-B3
EGR1 early growth response 1
ELK4 ELK4, ETS-domain protein (SRF accessory protein 1)
ESR1 estrogen receptor 1
EZR ezrin
FAM76A family with sequence similarity 76, member A
FBN2 fibrillin 2
FOXN3 forkhead box N3
FRY furry homolog (Drosophila)
GIT2 G protein-coupled receptor kinase interacting ArfGAP 2
GLP1R glucagon-like peptide 1 receptor
GPR107 G protein-coupled receptor 107
GPR15 G protein-coupled receptor 15
GTF3C2 general transcription factor IIIC, polypeptide 2, beta 110kDa
HNRNPD heterogeneous nuclear ribonucleoprotein D (AU-rich element RNA binding protein 1, 37kDa)
IGFBP7 insulin-like growth factor binding protein 7
ISG20L2 interferon stimulated exonuclease gene 20kDa-like 2
JADE2 jade family PHD finger 2
KAT6A K(lysine) acetyltransferase 6A
KCNAB1 potassium channel, voltage gated subfamily A regulatory beta subunit 1
KCNJ3 potassium channel, inwardly rectifying subfamily J, member 3
KLHL20 kelch-like family member 20
LDHC lactate dehydrogenase C
LRAT lecithin retinol acyltransferase (phosphatidylcholine--retinol O-acyltransferase)
LSS lanosterol synthase (2,3-oxidosqualene-lanosterol cyclase)
MAP2K7 mitogen-activated protein kinase kinase 7
MAP3K9 mitogen-activated protein kinase kinase kinase 9
MEF2D myocyte enhancer factor 2D
MMRN2 multimerin 2
MVD mevalonate (diphospho) decarboxylase
N4BP2L2-IT2 N4BPL2 intronic transcript 2
ONECUT2 one cut homeobox 2
PDGFA platelet-derived growth factor alpha polypeptide
PHTF2 putative homeodomain transcription factor 2
PLEKHM1 pleckstrin homology domain containing, family M (with RUN domain) member 1
PRDM2 PR domain containing 2, with ZNF domain
PRKCE protein kinase C, epsilon
PTGS2 prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)
PVRL1 poliovirus receptor-related 1 (herpesvirus entry mediator C)
RAB6B RAB6B, member RAS oncogene family
RBM14 RNA binding motif protein 14
RBM34 RNA binding motif protein 34
RGS12 regulator of G-protein signaling 12
RHOBTB3 Rho-related BTB domain containing 3
ROR1 receptor tyrosine kinase-like orphan receptor 1
RPH3A rabphilin 3A
RPS4Y1 ribosomal protein S4, Y-linked 1
RUNX1 runt-related transcription factor 1
S100A5 S100 calcium binding protein A5
SCD stearoyl-CoA desaturase (delta-9-desaturase)
SEMA6D sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6D
SENP6 SUMO1/sentrin specific peptidase 6
SETDB1 SET domain, bifurcated 1
SIGLEC8 sialic acid binding Ig-like lectin 8
SIRPA signal-regulatory protein alpha
SLC11A1 solute carrier family 11 (proton-coupled divalent metal ion transporter), member 1
SLC2A1 solute carrier family 2 (facilitated glucose transporter), member 1
SLC35F5 solute carrier family 35, member F5
SLC6A13 solute carrier family 6 (neurotransmitter transporter), member 13
SLC6A6 solute carrier family 6 (neurotransmitter transporter), member 6
SNTB1 syntrophin, beta 1 (dystrophin-associated protein A1, 59kDa, basic component 1)
SPRR1A small proline-rich protein 1A
SRCAP Snf2-related CREBBP activator protein
TACC1 transforming, acidic coiled-coil containing protein 1
TGM2 transglutaminase 2
TGM4 transglutaminase 4
TMPRSS15 transmembrane protease, serine 15
TNPO2 transportin 2
TSC2 tuberous sclerosis 2
TUBA3C tubulin, alpha 3c
VCL vinculin
WHSC1L1 Wolf-Hirschhorn syndrome candidate 1-like 1
ZC3H13 zinc finger CCCH-type containing 13
ZZEF1 zinc finger, ZZ-type with EF-hand domain 1

decreased expression

Symbol Name
ANKH ANKH inorganic pyrophosphate transport regulator
ANKRA2 ankyrin repeat, family A (RFXANK-like), 2
AP4M1 adaptor-related protein complex 4, mu 1 subunit
ARHGAP22 Rho GTPase activating protein 22
ASPSCR1 alveolar soft part sarcoma chromosome region, candidate 1
ATF7IP2 activating transcription factor 7 interacting protein 2
B3GNT3 UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 3
BAHCC1 BAH domain and coiled-coil containing 1
BRCA1 breast cancer 1, early onset
C19ORF40 chromosome 19 open reading frame 40
C5 complement component 5
C7ORF49 chromosome 7 open reading frame 49
CASP8AP2 caspase 8 associated protein 2
CBX8 chromobox homolog 8
CFAP44 cilia and flagella associated protein 44
COBL cordon-bleu WH2 repeat protein
COG4 component of oligomeric golgi complex 4
CSTF3 cleavage stimulation factor, 3' pre-RNA, subunit 3, 77kDa
DENND4A DENN/MADD domain containing 4A
DENND4B DENN/MADD domain containing 4B
DEPTOR DEP domain containing MTOR-interacting protein
DEXI Dexi homolog (mouse)
DIO3 deiodinase, iodothyronine, type III
DIXDC1 DIX domain containing 1
DOLK dolichol kinase
DPF3 D4, zinc and double PHD fingers, family 3
DUS2 dihydrouridine synthase 2
E2F8 E2F transcription factor 8
EEF2KMT eukaryotic elongation factor 2 lysine methyltransferase
EFNA3 ephrin-A3
EHHADH enoyl-CoA, hydratase/3-hydroxyacyl CoA dehydrogenase
ERN2 endoplasmic reticulum to nucleus signaling 2
FAM86B1 family with sequence similarity 86, member B1
FAM86C1 family with sequence similarity 86, member C1
GALK1 galactokinase 1
GFPT2 glutamine-fructose-6-phosphate transaminase 2
GINS1 GINS complex subunit 1 (Psf1 homolog)
GTF2H4 general transcription factor IIH, polypeptide 4, 52kDa
GTPBP2 GTP binding protein 2
H1F0 H1 histone family, member 0
HDAC4 histone deacetylase 4
HIST1H1D histone cluster 1, H1d
HOXB13 homeobox B13
HSD17B2 hydroxysteroid (17-beta) dehydrogenase 2
INTS6 integrator complex subunit 6
JMJD4 jumonji domain containing 4
KRCC1 lysine-rich coiled-coil 1
KRT4 keratin 4, type II
LINC00339 long intergenic non-protein coding RNA 339
LINC00341 long intergenic non-protein coding RNA 341
MAVS mitochondrial antiviral signaling protein
MCMBP minichromosome maintenance complex binding protein
MKS1 Meckel syndrome, type 1
MUS81 MUS81 structure-specific endonuclease subunit
MUTYH mutY homolog
MYOZ3 myozenin 3
NAT6 N-acetyltransferase 6 (GCN5-related)
NDE1 nudE neurodevelopment protein 1
OLFML2A olfactomedin-like 2A
OR7E156P olfactory receptor, family 7, subfamily E, member 156 pseudogene
P3H4 prolyl 3-hydroxylase family member 4 (non-enzymatic)
PAGR1 PAXIP1 associated glutamate-rich protein 1
PAK3 p21 protein (Cdc42/Rac)-activated kinase 3
PAN2 PAN2 poly(A) specific ribonuclease subunit
PCYOX1L prenylcysteine oxidase 1 like
PIGZ phosphatidylinositol glycan anchor biosynthesis, class Z
PLEKHB1 pleckstrin homology domain containing, family B (evectins) member 1
PLXNA2 plexin A2
POLA2 polymerase (DNA directed), alpha 2, accessory subunit
PPP1R10 protein phosphatase 1, regulatory subunit 10
PRR3 proline rich 3
PTK6 protein tyrosine kinase 6
PTPN9 protein tyrosine phosphatase, non-receptor type 9
PYCRL pyrroline-5-carboxylate reductase-like
QTRT1 queuine tRNA-ribosyltransferase 1
RBM15B RNA binding motif protein 15B
RGP1 RGP1 retrograde golgi transport homolog (S. cerevisiae)
RHPN1-AS1 RHPN1 antisense RNA 1 (head to head)
RNF122 ring finger protein 122
RPP25 ribonuclease P/MRP 25kDa subunit
SAYSD1 SAYSVFN motif domain containing 1
SH3TC1 SH3 domain and tetratricopeptide repeats 1
SH3TC2 SH3 domain and tetratricopeptide repeats 2
SLC2A10 solute carrier family 2 (facilitated glucose transporter), member 10
SLC4A3 solute carrier family 4 (anion exchanger), member 3
SMARCAL1 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a-like 1
SMPD2 sphingomyelin phosphodiesterase 2, neutral membrane (neutral sphingomyelinase)
SMUG1 single-strand-selective monofunctional uracil-DNA glycosylase 1
ST6GALNAC5 ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 5
TAF15 TAF15 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 68kDa
TENM4 teneurin transmembrane protein 4
TMEM194A transmembrane protein 194A
TNS2 tensin 2
TRAPPC12 trafficking protein particle complex 12
TRMT1L tRNA methyltransferase 1 homolog (S. cerevisiae)-like
TRMT2A tRNA methyltransferase 2 homolog A (S. cerevisiae)
USP20 ubiquitin specific peptidase 20
VASH2 vasohibin 2
ZNF189 zinc finger protein 189
ZNF76 zinc finger protein 76