0179445-0000-4292 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

195 genes differentially expressed following the 0179445-0000-4292 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ACRV1 acrosomal vesicle protein 1
AFF1 AF4/FMR2 family, member 1
ALDH3B2 aldehyde dehydrogenase 3 family, member B2
ALOX5AP arachidonate 5-lipoxygenase-activating protein
AMOT angiomotin
ANGPTL2 angiopoietin-like 2
ANKLE2 ankyrin repeat and LEM domain containing 2
ARNT aryl hydrocarbon receptor nuclear translocator
ARTN artemin
ATAT1 alpha tubulin acetyltransferase 1
BCL2L14 BCL2-like 14 (apoptosis facilitator)
BMPR1B bone morphogenetic protein receptor, type IB
CA1 carbonic anhydrase I
CACFD1 calcium channel flower domain containing 1
CASZ1 castor zinc finger 1
CD36 CD36 molecule (thrombospondin receptor)
CD40 CD40 molecule, TNF receptor superfamily member 5
CHI3L1 chitinase 3-like 1 (cartilage glycoprotein-39)
CIB2 calcium and integrin binding family member 2
CNOT4 CCR4-NOT transcription complex, subunit 4
COX6A2 cytochrome c oxidase subunit VIa polypeptide 2
CRTC1 CREB regulated transcription coactivator 1
CYP2A7 cytochrome P450, family 2, subfamily A, polypeptide 7
DNAJA4 DnaJ (Hsp40) homolog, subfamily A, member 4
DNAJC4 DnaJ (Hsp40) homolog, subfamily C, member 4
DZIP1 DAZ interacting zinc finger protein 1
EPS8L1 EPS8-like 1
ERN2 endoplasmic reticulum to nucleus signaling 2
FAM149B1 family with sequence similarity 149, member B1
FGA fibrinogen alpha chain
FGF8 fibroblast growth factor 8 (androgen-induced)
FSCN3 fascin actin-bundling protein 3, testicular
GJD2 gap junction protein, delta 2, 36kDa
GNAQ guanine nucleotide binding protein (G protein), q polypeptide
GPA33 glycoprotein A33 (transmembrane)
GPER1 G protein-coupled estrogen receptor 1
GPNMB glycoprotein (transmembrane) nmb
GPR17 G protein-coupled receptor 17
HHAT hedgehog acyltransferase
HLA-DOA major histocompatibility complex, class II, DO alpha
IL6ST interleukin 6 signal transducer
IPO8 importin 8
IRF4 interferon regulatory factor 4
ITGB1 integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12)
LIMD1 LIM domains containing 1
LINC00652 long intergenic non-protein coding RNA 652
LRCH1 leucine-rich repeats and calponin homology (CH) domain containing 1
MAN1C1 mannosidase, alpha, class 1C, member 1
MAP1A microtubule-associated protein 1A
MAP3K13 mitogen-activated protein kinase kinase kinase 13
MED18 mediator complex subunit 18
MYBPC3 myosin binding protein C, cardiac
MYLPF myosin light chain, phosphorylatable, fast skeletal muscle
NPHP1 nephronophthisis 1 (juvenile)
NR0B2 nuclear receptor subfamily 0, group B, member 2
NTM neurotrimin
NUDT18 nudix (nucleoside diphosphate linked moiety X)-type motif 18
OBSCN obscurin, cytoskeletal calmodulin and titin-interacting RhoGEF
OSR2 odd-skipped related transciption factor 2
OXCT2 3-oxoacid CoA transferase 2
PCDHGA8 protocadherin gamma subfamily A, 8
PDLIM5 PDZ and LIM domain 5
PLIN2 perilipin 2
POU4F2 POU class 4 homeobox 2
PPP1R3D protein phosphatase 1, regulatory subunit 3D
PRDM14 PR domain containing 14
PRO2964 uncharacterized protein PRO2964
PRR34 proline rich 34
PTPN11 protein tyrosine phosphatase, non-receptor type 11
PTRF polymerase I and transcript release factor
RAB2A RAB2A, member RAS oncogene family
RET ret proto-oncogene
RFXAP regulatory factor X-associated protein
RHO rhodopsin
RNGTT RNA guanylyltransferase and 5'-phosphatase
RPLP2 ribosomal protein, large, P2
RRN3P1 RNA polymerase I transcription factor homolog (S. cerevisiae) pseudogene 1
SCN5A sodium channel, voltage gated, type V alpha subunit
SERPINA7 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 7
SLC4A4 solute carrier family 4 (sodium bicarbonate cotransporter), member 4
SOX30 SRY (sex determining region Y)-box 30
SPARCL1 SPARC-like 1 (hevin)
TAPBP TAP binding protein (tapasin)
TAS2R4 taste receptor, type 2, member 4
TGM4 transglutaminase 4
THBD thrombomodulin
TMEM144 transmembrane protein 144
TPM3 tropomyosin 3
TPSG1 tryptase gamma 1
TRIM15 tripartite motif containing 15
TSC22D2 TSC22 domain family, member 2
TSPAN1 tetraspanin 1
VCAN versican
ZBED4 zinc finger, BED-type containing 4
ZFX zinc finger protein, X-linked
ZNF44 zinc finger protein 44
ZNF771 zinc finger protein 771
ZSCAN18 zinc finger and SCAN domain containing 18

decreased expression

Symbol Name
A1CF APOBEC1 complementation factor
ABCC5 ATP-binding cassette, sub-family C (CFTR/MRP), member 5
ABHD8 abhydrolase domain containing 8
ALDH2 aldehyde dehydrogenase 2 family (mitochondrial)
APOL6 apolipoprotein L, 6
ASPSCR1 alveolar soft part sarcoma chromosome region, candidate 1
AXIN1 axin 1
BAHCC1 BAH domain and coiled-coil containing 1
CARM1 coactivator-associated arginine methyltransferase 1
CBX4 chromobox homolog 4
CCDC85C coiled-coil domain containing 85C
CCNO cyclin O
CDH7 cadherin 7, type 2
CENPT centromere protein T
CEP295 centrosomal protein 295kDa
CLUHP3 clustered mitochondria (cluA/CLU1) homolog pseudogene 3
CORO2A coronin, actin binding protein, 2A
DEF6 differentially expressed in FDCP 6 homolog (mouse)
ELP6 elongator acetyltransferase complex subunit 6
EN2 engrailed homeobox 2
ENTPD3 ectonucleoside triphosphate diphosphohydrolase 3
ERMAP erythroblast membrane-associated protein (Scianna blood group)
FANCF Fanconi anemia, complementation group F
FBXW7 F-box and WD repeat domain containing 7, E3 ubiquitin protein ligase
FCGR2A Fc fragment of IgG, low affinity IIa, receptor (CD32)
FOXD1 forkhead box D1
FOXN2 forkhead box N2
GALNS galactosamine (N-acetyl)-6-sulfatase
GALNT14 polypeptide N-acetylgalactosaminyltransferase 14
GDPD3 glycerophosphodiester phosphodiesterase domain containing 3
GTPBP2 GTP binding protein 2
H1FX H1 histone family, member X
HIST1H2AG histone cluster 1, H2ag
HIVEP3 human immunodeficiency virus type I enhancer binding protein 3
HYAL3 hyaluronoglucosaminidase 3
ITIH2 inter-alpha-trypsin inhibitor heavy chain 2
KIAA0319L KIAA0319-like
KIF13A kinesin family member 13A
KLHL25 kelch-like family member 25
KLHL36 kelch-like family member 36
LHPP phospholysine phosphohistidine inorganic pyrophosphate phosphatase
MANBA mannosidase, beta A, lysosomal
MFGE8 milk fat globule-EGF factor 8 protein
MGRN1 mahogunin ring finger 1, E3 ubiquitin protein ligase
MOXD1 monooxygenase, DBH-like 1
MUC3B mucin 3B, cell surface associated
MYO1D myosin ID
NABP2 nucleic acid binding protein 2
NDRG4 NDRG family member 4
NOL6 nucleolar protein 6 (RNA-associated)
NTSR1 neurotensin receptor 1 (high affinity)
PALM paralemmin
PARP6 poly (ADP-ribose) polymerase family, member 6
PDE12 phosphodiesterase 12
PHLPP1 PH domain and leucine rich repeat protein phosphatase 1
PIM1 Pim-1 proto-oncogene, serine/threonine kinase
PIP5K1C phosphatidylinositol-4-phosphate 5-kinase, type I, gamma
PLEKHO2 pleckstrin homology domain containing, family O member 2
PLXNB3 plexin B3
POLA2 polymerase (DNA directed), alpha 2, accessory subunit
POLL polymerase (DNA directed), lambda
PPP2R3B protein phosphatase 2, regulatory subunit B'', beta
PRICKLE3 prickle homolog 3 (Drosophila)
PRR15L proline rich 15-like
PYCRL pyrroline-5-carboxylate reductase-like
RAD54L2 RAD54-like 2 (S. cerevisiae)
RBM42 RNA binding motif protein 42
RNF19B ring finger protein 19B
RPGRIP1L RPGRIP1-like
RPP25 ribonuclease P/MRP 25kDa subunit
SCAMP4 secretory carrier membrane protein 4
SCIN scinderin
SH3TC2 SH3 domain and tetratricopeptide repeats 2
SIRAL2 SIR2 antiphage like 2
SLC44A1 solute carrier family 44 (choline transporter), member 1
SLC9A8 solute carrier family 9, subfamily A (NHE8, cation proton antiporter 8), member 8
SPTBN2 spectrin, beta, non-erythrocytic 2
SSBP3 single stranded DNA binding protein 3
ST6GALNAC2 ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2
STRN4 striatin, calmodulin binding protein 4
STX1A syntaxin 1A (brain)
SUN2 Sad1 and UNC84 domain containing 2
TGFBRAP1 transforming growth factor, beta receptor associated protein 1
TINAGL1 tubulointerstitial nephritis antigen-like 1
TTLL7 tubulin tyrosine ligase-like family member 7
USP18 ubiquitin specific peptidase 18
USP20 ubiquitin specific peptidase 20
USP5 ubiquitin specific peptidase 5 (isopeptidase T)
WDR46 WD repeat domain 46
WNT10B wingless-type MMTV integration site family, member 10B
XAB2 XPA binding protein 2
YY2 YY2 transcription factor
ZFHX3 zinc finger homeobox 3
ZNF667 zinc finger protein 667
ZNF76 zinc finger protein 76
ZNF778 zinc finger protein 778
ZYX zyxin