0179445-0000-4758 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

199 genes differentially expressed following the 0179445-0000-4758 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ABCC3 ATP-binding cassette, sub-family C (CFTR/MRP), member 3
ADTRP androgen-dependent TFPI-regulating protein
AQP1 aquaporin 1 (Colton blood group)
BAZ2A bromodomain adjacent to zinc finger domain, 2A
BMP1 bone morphogenetic protein 1
C10ORF95 chromosome 10 open reading frame 95
C19ORF66 chromosome 19 open reading frame 66
CCDC134 coiled-coil domain containing 134
CCDC28B coiled-coil domain containing 28B
CCL22 chemokine (C-C motif) ligand 22
CCND2 cyclin D2
CDC14B cell division cycle 14B
CDHR2 cadherin-related family member 2
CIDEB cell death-inducing DFFA-like effector b
CTBS chitobiase, di-N-acetyl-
CXCL8 chemokine (C-X-C motif) ligand 8
DSC3 desmocollin 3
DUSP13 dual specificity phosphatase 13
EDN1 endothelin 1
EDNRA endothelin receptor type A
EMID1 EMI domain containing 1
ERBB4 erb-b2 receptor tyrosine kinase 4
FBLN1 fibulin 1
FBXL7 F-box and leucine-rich repeat protein 7
FMO4 flavin containing monooxygenase 4
FRMD8 FERM domain containing 8
GLP1R glucagon-like peptide 1 receptor
GNG13 guanine nucleotide binding protein (G protein), gamma 13
GPATCH4 G patch domain containing 4
GRIP2 glutamate receptor interacting protein 2
GSK3A glycogen synthase kinase 3 alpha
HERC3 HECT and RLD domain containing E3 ubiquitin protein ligase 3
HFE hemochromatosis
HLCS holocarboxylase synthetase (biotin-(proprionyl-CoA-carboxylase (ATP-hydrolysing)) ligase)
HPS1 Hermansky-Pudlak syndrome 1
HRK harakiri, BCL2 interacting protein
ICOSLG inducible T-cell co-stimulator ligand
INPP4A inositol polyphosphate-4-phosphatase, type I, 107kDa
ITGBL1 integrin, beta-like 1 (with EGF-like repeat domains)
KCNH2 potassium channel, voltage gated eag related subfamily H, member 2
KCNJ5 potassium channel, inwardly rectifying subfamily J, member 5
KCNK12 potassium channel, two pore domain subfamily K, member 12
LAMB4 laminin, beta 4
LAT2 linker for activation of T cells family, member 2
LINC00597 long intergenic non-protein coding RNA 597
LTBP4 latent transforming growth factor beta binding protein 4
MALL mal, T-cell differentiation protein-like
MAPK11 mitogen-activated protein kinase 11
MARK4 MAP/microtubule affinity-regulating kinase 4
MC2R melanocortin 2 receptor (adrenocorticotropic hormone)
MED25 mediator complex subunit 25
MNMIP1 manchette microtubule inner protein 1
MTA1 metastasis associated 1
NEUROD1 neuronal differentiation 1
NR4A2 nuclear receptor subfamily 4, group A, member 2
OR2B6 olfactory receptor, family 2, subfamily B, member 6
OSGIN1 oxidative stress induced growth inhibitor 1
PKNOX1 PBX/knotted 1 homeobox 1
PLCD1 phospholipase C, delta 1
PLXNA2 plexin A2
PRAMEF11 PRAME family member 11
PRDM14 PR domain containing 14
PTHLH parathyroid hormone-like hormone
PTPRJ protein tyrosine phosphatase, receptor type, J
RAB3IL1 RAB3A interacting protein (rabin3)-like 1
RBBP9 retinoblastoma binding protein 9
RBMS2 RNA binding motif, single stranded interacting protein 2
REL v-rel avian reticuloendotheliosis viral oncogene homolog
RELB v-rel avian reticuloendotheliosis viral oncogene homolog B
RNF125 ring finger protein 125, E3 ubiquitin protein ligase
RPS6KA2 ribosomal protein S6 kinase, 90kDa, polypeptide 2
S100A8 S100 calcium binding protein A8
SCN10A sodium channel, voltage gated, type X alpha subunit
SCN11A sodium channel, voltage gated, type XI alpha subunit
SEMA4G sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4G
SLC10A1 solute carrier family 10 (sodium/bile acid cotransporter), member 1
SLC24A1 solute carrier family 24 (sodium/potassium/calcium exchanger), member 1
SLC30A4 solute carrier family 30 (zinc transporter), member 4
SLC6A6 solute carrier family 6 (neurotransmitter transporter), member 6
SLC7A8 solute carrier family 7 (amino acid transporter light chain, L system), member 8
SMAD1 SMAD family member 1
SMC4 structural maintenance of chromosomes 4
SNED1 sushi, nidogen and EGF-like domains 1
SYT12 synaptotagmin XII
SYT5 synaptotagmin V
TBC1D2 TBC1 domain family, member 2
TCP11L1 t-complex 11, testis-specific-like 1
TMEM45A transmembrane protein 45A
TOP3A topoisomerase (DNA) III alpha
TRANK1 tetratricopeptide repeat and ankyrin repeat containing 1
TRIM10 tripartite motif containing 10
TTC39A tetratricopeptide repeat domain 39A
UBR4 ubiquitin protein ligase E3 component n-recognin 4
UNC13A unc-13 homolog A (C. elegans)
UTS2 urotensin 2
VNN2 vanin 2
XYLB xylulokinase homolog (H. influenzae)
ZCCHC24 zinc finger, CCHC domain containing 24
ZNF362 zinc finger protein 362

decreased expression

Symbol Name
ABCC2 ATP-binding cassette, sub-family C (CFTR/MRP), member 2
AKR1B1 aldo-keto reductase family 1, member B1 (aldose reductase)
AKT2 v-akt murine thymoma viral oncogene homolog 2
ALKBH4 alkB, alkylation repair homolog 4 (E. coli)
AMPD1 adenosine monophosphate deaminase 1
AMT aminomethyltransferase
ARSB arylsulfatase B
ATAT1 alpha tubulin acetyltransferase 1
BATF basic leucine zipper transcription factor, ATF-like
C1ORF105 chromosome 1 open reading frame 105
C1ORF21 chromosome 1 open reading frame 21
C1QTNF9B-AS1 C1QTNF9B antisense RNA 1
CASP3 caspase 3, apoptosis-related cysteine peptidase
CCNO cyclin O
CCRN4L CCR4 carbon catabolite repression 4-like (S. cerevisiae)
CD34 CD34 molecule
CES3 carboxylesterase 3
CFAP69 cilia and flagella associated protein 69
CUZD1 CUB and zona pellucida-like domains 1
CXADR coxsackie virus and adenovirus receptor
DYSF dysferlin
ELMO3 engulfment and cell motility 3
ELP6 elongator acetyltransferase complex subunit 6
ETAA1 Ewing tumor-associated antigen 1
EXTL3 exostosin-like glycosyltransferase 3
FAM110B family with sequence similarity 110, member B
FAM120C family with sequence similarity 120C
GADD45G growth arrest and DNA-damage-inducible, gamma
GIT1 G protein-coupled receptor kinase interacting ArfGAP 1
GNA14 guanine nucleotide binding protein (G protein), alpha 14
GSPT2 G1 to S phase transition 2
GTF3C5 general transcription factor IIIC, polypeptide 5, 63kDa
HAMP hepcidin antimicrobial peptide
HCG4 HLA complex group 4 (non-protein coding)
HIST1H2AI histone cluster 1, H2ai
HIVEP3 human immunodeficiency virus type I enhancer binding protein 3
HTR1E 5-hydroxytryptamine (serotonin) receptor 1E, G protein-coupled
IFI27 interferon, alpha-inducible protein 27
IFI6 interferon, alpha-inducible protein 6
IFT54 intraflagellar transport 54
JMJD4 jumonji domain containing 4
KCNMB1 potassium channel subfamily M regulatory beta subunit 1
KCTD17 potassium channel tetramerization domain containing 17
KDM5C lysine (K)-specific demethylase 5C
KDM8 lysine (K)-specific demethylase 8
KLK5 kallikrein-related peptidase 5
LAMP3 lysosomal-associated membrane protein 3
LARP6 La ribonucleoprotein domain family, member 6
LHX1 LIM homeobox 1
LHX6 LIM homeobox 6
LMO2 LIM domain only 2 (rhombotin-like 1)
LTBP2 latent transforming growth factor beta binding protein 2
LY6G6C lymphocyte antigen 6 complex, locus G6C
MFGE8 milk fat globule-EGF factor 8 protein
MRPS18C mitochondrial ribosomal protein S18C
MYLK myosin light chain kinase
NAT6 N-acetyltransferase 6 (GCN5-related)
NDUFAF5 NADH dehydrogenase (ubiquinone) complex I, assembly factor 5
NFKBIL1 nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor-like 1
NIPAL2 NIPA-like domain containing 2
NME5 NME/NM23 family member 5
NPR3 natriuretic peptide receptor 3
NXPH4 neurexophilin 4
OGDH oxoglutarate (alpha-ketoglutarate) dehydrogenase (lipoamide)
PACS1 phosphofurin acidic cluster sorting protein 1
PAOX polyamine oxidase (exo-N4-amino)
PARD6A par-6 family cell polarity regulator alpha
PAX9 paired box 9
PGP phosphoglycolate phosphatase
PLA2G10 phospholipase A2, group X
PMM1 phosphomannomutase 1
QPCTL glutaminyl-peptide cyclotransferase-like
RCN1 reticulocalbin 1, EF-hand calcium binding domain
SERGEF secretion regulating guanine nucleotide exchange factor
SIPA1 signal-induced proliferation-associated 1
SLC17A2 solute carrier family 17, member 2
SLC25A22 solute carrier family 25 (mitochondrial carrier: glutamate), member 22
SLC2A6 solute carrier family 2 (facilitated glucose transporter), member 6
SLC9A5 solute carrier family 9, subfamily A (NHE5, cation proton antiporter 5), member 5
SMARCD3 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 3
SMR3A submaxillary gland androgen regulated protein 3A
STEAP1 six transmembrane epithelial antigen of the prostate 1
STK16 serine/threonine kinase 16
SULT1B1 sulfotransferase family, cytosolic, 1B, member 1
SUN2 Sad1 and UNC84 domain containing 2
TARP TCR gamma alternate reading frame protein
TCTA T-cell leukemia translocation altered
TMEM121 transmembrane protein 121
TUBA3C tubulin, alpha 3c
TWISTNB TWIST neighbor
UBQLN4 ubiquilin 4
UNC93B1 unc-93 homolog B1 (C. elegans)
UPK3B uroplakin 3B
USB1 U6 snRNA biogenesis 1
VEGFB vascular endothelial growth factor B
VPS9D1 VPS9 domain containing 1
ZIC3 Zic family member 3
ZNF423 zinc finger protein 423
ZNF428 zinc finger protein 428
ZNF446 zinc finger protein 446