0316684-0000-7093 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

199 genes differentially expressed following the 0316684-0000-7093 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ADAP1 ArfGAP with dual PH domains 1
ADM adrenomedullin
ADRBK2 adrenergic, beta, receptor kinase 2
ANKRD12 ankyrin repeat domain 12
APLP1 amyloid beta (A4) precursor-like protein 1
ARMCX4 armadillo repeat containing, X-linked 4
BCL2L11 BCL2-like 11 (apoptosis facilitator)
BMP2K BMP2 inducible kinase
BTN2A1 butyrophilin, subfamily 2, member A1
C5ORF45 chromosome 5 open reading frame 45
CA12 carbonic anhydrase XII
CCDC9 coiled-coil domain containing 9
CDK3 cyclin-dependent kinase 3
CDYL chromodomain protein, Y-like
CEP290 centrosomal protein 290kDa
CNNM2 cyclin and CBS domain divalent metal cation transport mediator 2
CSTA cystatin A (stefin A)
DFNB31 deafness, autosomal recessive 31
DND1 DND microRNA-mediated repression inhibitor 1
DOCK4 dedicator of cytokinesis 4
DYRK3 dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 3
EEF1D eukaryotic translation elongation factor 1 delta (guanine nucleotide exchange protein)
EPHA3 EPH receptor A3
EPM2A epilepsy, progressive myoclonus type 2A, Lafora disease (laforin)
F3 coagulation factor III (thromboplastin, tissue factor)
FAM171A1 family with sequence similarity 171, member A1
FZR1 fizzy/cell division cycle 20 related 1 (Drosophila)
GDPD5 glycerophosphodiester phosphodiesterase domain containing 5
HFE hemochromatosis
HLA-E major histocompatibility complex, class I, E
HPS1 Hermansky-Pudlak syndrome 1
HSPG2 heparan sulfate proteoglycan 2
IL6ST interleukin 6 signal transducer
KAZALD1 Kazal-type serine peptidase inhibitor domain 1
KCNJ3 potassium channel, inwardly rectifying subfamily J, member 3
LMF2 lipase maturation factor 2
LOC157562 uncharacterized LOC157562
MAGOH2P mago-nashi homolog 2, pseudogene
MAPK7 mitogen-activated protein kinase 7
MARC2 mitochondrial amidoxime reducing component 2
MERTK MER proto-oncogene, tyrosine kinase
NEAT1 nuclear paraspeckle assembly transcript 1 (non-protein coding)
NKIRAS2 NFKB inhibitor interacting Ras-like 2
NOTCH2 notch 2
NR3C1 nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor)
NUDT13 nudix (nucleoside diphosphate linked moiety X)-type motif 13
OAS3 2'-5'-oligoadenylate synthetase 3, 100kDa
OPA3 optic atrophy 3 (autosomal recessive, with chorea and spastic paraplegia)
PARPBP PARP1 binding protein
PCDH7 protocadherin 7
PCDHB8 protocadherin beta 8
PDGFB platelet-derived growth factor beta polypeptide
PGAP1 post-GPI attachment to proteins 1
PGR progesterone receptor
PI4KB phosphatidylinositol 4-kinase, catalytic, beta
PIDD1 p53-induced death domain protein 1
PIGC phosphatidylinositol glycan anchor biosynthesis, class C
PLEKHM1 pleckstrin homology domain containing, family M (with RUN domain) member 1
POLH polymerase (DNA directed), eta
PRMT2 protein arginine methyltransferase 2
PSEN2 presenilin 2
RASSF1 Ras association (RalGDS/AF-6) domain family member 1
RBM3 RNA binding motif (RNP1, RRM) protein 3
RECQL4 RecQ protein-like 4
RGS10 regulator of G-protein signaling 10
RNASEL ribonuclease L (2',5'-oligoisoadenylate synthetase-dependent)
RPS28 ribosomal protein S28
SAT1 spermidine/spermine N1-acetyltransferase 1
SETD1B SET domain containing 1B
SF3A2 splicing factor 3a, subunit 2, 66kDa
SHARPIN SHANK-associated RH domain interactor
SIGLEC7 sialic acid binding Ig-like lectin 7
SLC39A9 solute carrier family 39, member 9
SMC1A structural maintenance of chromosomes 1A
SRPR signal recognition particle receptor (docking protein)
SS18 synovial sarcoma translocation, chromosome 18
STAG3 stromal antigen 3
STK38L serine/threonine kinase 38 like
SUGP2 SURP and G patch domain containing 2
SYBU syntabulin (syntaxin-interacting)
TBC1D22A TBC1 domain family, member 22A
TDRD3 tudor domain containing 3
TMEM57 transmembrane protein 57
TMOD1 tropomodulin 1
TNFRSF10B tumor necrosis factor receptor superfamily, member 10b
TRABD TraB domain containing
TRAF4 TNF receptor-associated factor 4
TRIM3 tripartite motif containing 3
TUBA3C tubulin, alpha 3c
USF2 upstream transcription factor 2, c-fos interacting
WDR4 WD repeat domain 4
ZBTB43 zinc finger and BTB domain containing 43
ZDHHC11 zinc finger, DHHC-type containing 11
ZFAND6 zinc finger, AN1-type domain 6
ZHX3 zinc fingers and homeoboxes 3
ZNF205 zinc finger protein 205
ZNF446 zinc finger protein 446
ZNF518A zinc finger protein 518A
ZNF573 zinc finger protein 573
ZNF821 zinc finger protein 821

decreased expression

Symbol Name
ALG12 ALG12, alpha-1,6-mannosyltransferase
ARMC7 armadillo repeat containing 7
ASAP1-IT1 ASAP1 intronic transcript 1
ASCC2 activating signal cointegrator 1 complex subunit 2
B3GNT4 UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 4
BIK BCL2-interacting killer (apoptosis-inducing)
CAMTA1 calmodulin binding transcription activator 1
CAPG capping protein (actin filament), gelsolin-like
CCDC57 coiled-coil domain containing 57
CCNL2 cyclin L2
CEP85 centrosomal protein 85kDa
CHAC1 ChaC glutathione-specific gamma-glutamylcyclotransferase 1
CHMP6 charged multivesicular body protein 6
CNKSR1 connector enhancer of kinase suppressor of Ras 1
CORO1A coronin, actin binding protein, 1A
CRYZ crystallin, zeta (quinone reductase)
CWF19L1 CWF19-like 1, cell cycle control (S. pombe)
DNAL4 dynein, axonemal, light chain 4
DUSP13 dual specificity phosphatase 13
DUSP4 dual specificity phosphatase 4
EGR3 early growth response 3
EIF2S3 eukaryotic translation initiation factor 2, subunit 3 gamma, 52kDa
ENTPD7 ectonucleoside triphosphate diphosphohydrolase 7
EPHA2 EPH receptor A2
EXOC5 exocyst complex component 5
FABP5 fatty acid binding protein 5 (psoriasis-associated)
FBXO22 F-box protein 22
FOLR1 folate receptor 1 (adult)
FOSL1 FOS-like antigen 1
FOXC1 forkhead box C1
FSTL3 follistatin-like 3 (secreted glycoprotein)
GALNT14 polypeptide N-acetylgalactosaminyltransferase 14
GMPPA GDP-mannose pyrophosphorylase A
HIST1H2AJ histone cluster 1, H2aj
HLA-J major histocompatibility complex, class I, J (pseudogene)
INF2 inverted formin, FH2 and WH2 domain containing
IREB2 iron-responsive element binding protein 2
ITGA2 integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor)
KCNMB3 potassium channel subfamily M regulatory beta subunit 3
KRT13 keratin 13, type I
LLGL2 lethal giant larvae homolog 2 (Drosophila)
LOC100287590 uncharacterized LOC100287590
LOC202181 SUMO-interacting motifs containing 1 pseudogene
MAD1L1 MAD1 mitotic arrest deficient-like 1 (yeast)
MAGI1 membrane associated guanylate kinase, WW and PDZ domain containing 1
MAN2C1 mannosidase, alpha, class 2C, member 1
MLF2 myeloid leukemia factor 2
MPDU1 mannose-P-dolichol utilization defect 1
MTERF1 mitochondrial transcription termination factor 1
NAV2 neuron navigator 2
NEK11 NIMA-related kinase 11
NKRF NFKB repressing factor
NR1D2 nuclear receptor subfamily 1, group D, member 2
NT5C 5', 3'-nucleotidase, cytosolic
NT5DC3 5'-nucleotidase domain containing 3
NUDT18 nudix (nucleoside diphosphate linked moiety X)-type motif 18
NUTF2 nuclear transport factor 2
OLFML3 olfactomedin-like 3
OTUB2 OTU deubiquitinase, ubiquitin aldehyde binding 2
P3H1 prolyl 3-hydroxylase 1
PFKFB3 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3
PIGL phosphatidylinositol glycan anchor biosynthesis, class L
PIM2 Pim-2 proto-oncogene, serine/threonine kinase
PRMT7 protein arginine methyltransferase 7
PSMC3 proteasome (prosome, macropain) 26S subunit, ATPase, 3
RAB3A RAB3A, member RAS oncogene family
RASA2 RAS p21 protein activator 2
RASGRP1 RAS guanyl releasing protein 1 (calcium and DAG-regulated)
RRNAD1 ribosomal RNA adenine dimethylase domain containing 1
SGTA small glutamine-rich tetratricopeptide repeat (TPR)-containing, alpha
SH2D4A SH2 domain containing 4A
SLC35C1 solute carrier family 35 (GDP-fucose transporter), member C1
SMG1 SMG1 phosphatidylinositol 3-kinase-related kinase
SMPDL3B sphingomyelin phosphodiesterase, acid-like 3B
SMUG1 single-strand-selective monofunctional uracil-DNA glycosylase 1
SNHG3 small nucleolar RNA host gene 3
SRPX sushi-repeat containing protein, X-linked
SYTL2 synaptotagmin-like 2
TAP1 transporter 1, ATP-binding cassette, sub-family B (MDR/TAP)
TBC1D17 TBC1 domain family, member 17
TCTA T-cell leukemia translocation altered
TET3 tet methylcytosine dioxygenase 3
TIMM50 translocase of inner mitochondrial membrane 50 homolog (S. cerevisiae)
TIMM9 translocase of inner mitochondrial membrane 9 homolog (yeast)
TMEM115 transmembrane protein 115
TMEM8A transmembrane protein 8A
TNS3 tensin 3
UBIAD1 UbiA prenyltransferase domain containing 1
UBXN6 UBX domain protein 6
URM1 ubiquitin related modifier 1
XYLT2 xylosyltransferase II
YIF1B Yip1 interacting factor homolog B (S. cerevisiae)
ZAK sterile alpha motif and leucine zipper containing kinase AZK
ZBTB6 zinc finger and BTB domain containing 6
ZNF141 zinc finger protein 141
ZNF276 zinc finger protein 276
ZNF331 zinc finger protein 331
ZNF34 zinc finger protein 34
ZNF8 zinc finger protein 8