0317956-0000-3774 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

196 genes differentially expressed following the 0317956-0000-3774 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ACE angiotensin I converting enzyme
ADAM19 ADAM metallopeptidase domain 19
ADAM8 ADAM metallopeptidase domain 8
ARG1 arginase 1
ATN1 atrophin 1
ATP2B2 ATPase, Ca++ transporting, plasma membrane 2
BBC3 BCL2 binding component 3
C11ORF16 chromosome 11 open reading frame 16
C21ORF2 chromosome 21 open reading frame 2
CA5B carbonic anhydrase VB, mitochondrial
CACNA1G calcium channel, voltage-dependent, T type, alpha 1G subunit
CACNB1 calcium channel, voltage-dependent, beta 1 subunit
CALHM2 calcium homeostasis modulator 2
CASP10 caspase 10, apoptosis-related cysteine peptidase
CCNK cyclin K
CD200 CD200 molecule
CEND1 cell cycle exit and neuronal differentiation 1
CLEC4E C-type lectin domain family 4, member E
CYP1A1 cytochrome P450, family 1, subfamily A, polypeptide 1
CYP2A6 cytochrome P450, family 2, subfamily A, polypeptide 6
DNAJC16 DnaJ (Hsp40) homolog, subfamily C, member 16
DRD2 dopamine receptor D2
DYRK1A dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A
EFNB3 ephrin-B3
FASLG Fas ligand (TNF superfamily, member 6)
FMO2 flavin containing monooxygenase 2 (non-functional)
GJA4 gap junction protein, alpha 4, 37kDa
GLB1L2 galactosidase, beta 1-like 2
GNAO1 guanine nucleotide binding protein (G protein), alpha activating activity polypeptide O
GPR85 G protein-coupled receptor 85
GRIP2 glutamate receptor interacting protein 2
GTPBP1 GTP binding protein 1
HBE1 hemoglobin, epsilon 1
HEATR6 HEAT repeat containing 6
HOXD9 homeobox D9
IDS iduronate 2-sulfatase
IFIH1 interferon induced with helicase C domain 1
IGFBP1 insulin-like growth factor binding protein 1
IL1RAPL1 interleukin 1 receptor accessory protein-like 1
IRF8 interferon regulatory factor 8
ITPK1 inositol-tetrakisphosphate 1-kinase
ITSN1 intersectin 1 (SH3 domain protein)
KCNA5 potassium channel, voltage gated shaker related subfamily A, member 5
LMO3 LIM domain only 3 (rhombotin-like 2)
LOC100294391 uncharacterized LOC100294391
LOC284244 uncharacterized LOC284244
LOC440895 two pore channel 3 pseudogene
MAP3K1 mitogen-activated protein kinase kinase kinase 1, E3 ubiquitin protein ligase
MCF2L MCF.2 cell line derived transforming sequence-like
MCHR1 melanin-concentrating hormone receptor 1
MEOX1 mesenchyme homeobox 1
MMP16 matrix metallopeptidase 16 (membrane-inserted)
MOBP myelin-associated oligodendrocyte basic protein
MON2 MON2 homolog (S. cerevisiae)
MPPE1 metallophosphoesterase 1
MTSS1L metastasis suppressor 1-like
MXD4 MAX dimerization protein 4
NCALD neurocalcin delta
NDUFAF5 NADH dehydrogenase (ubiquinone) complex I, assembly factor 5
NPBWR2 neuropeptides B/W receptor 2
NTRK1 neurotrophic tyrosine kinase, receptor, type 1
NUMA1 nuclear mitotic apparatus protein 1
OAS1 2'-5'-oligoadenylate synthetase 1, 40/46kDa
OPCML opioid binding protein/cell adhesion molecule-like
OR1G1 olfactory receptor, family 1, subfamily G, member 1
P2RY11 purinergic receptor P2Y, G-protein coupled, 11
PAQR6 progestin and adipoQ receptor family member VI
PCDHB3 protocadherin beta 3
PDLIM3 PDZ and LIM domain 3
PDLIM4 PDZ and LIM domain 4
PFKFB4 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 4
PTPN18 protein tyrosine phosphatase, non-receptor type 18 (brain-derived)
PTPRH protein tyrosine phosphatase, receptor type, H
RAB6B RAB6B, member RAS oncogene family
RASGRF1 Ras protein-specific guanine nucleotide-releasing factor 1
RASL11B RAS-like, family 11, member B
RBFOX1 RNA binding protein, fox-1 homolog (C. elegans) 1
RHAG Rh-associated glycoprotein
RUNX1 runt-related transcription factor 1
SCN1B sodium channel, voltage gated, type I beta subunit
SEMA5A sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5A
SEMA7A semaphorin 7A, GPI membrane anchor (John Milton Hagen blood group)
SH2D3A SH2 domain containing 3A
SIGLEC8 sialic acid binding Ig-like lectin 8
SLAMF7 SLAM family member 7
SLC6A20 solute carrier family 6 (proline IMINO transporter), member 20
SMR3A submaxillary gland androgen regulated protein 3A
SPINK2 serine peptidase inhibitor, Kazal type 2 (acrosin-trypsin inhibitor)
ST6GALNAC2 ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2
SYCE1L synaptonemal complex central element protein 1-like
SYP synaptophysin
TBC1D2 TBC1 domain family, member 2
TCF7 transcription factor 7 (T-cell specific, HMG-box)
TNFRSF13B tumor necrosis factor receptor superfamily, member 13B
TTC12 tetratricopeptide repeat domain 12
UBXN1 UBX domain protein 1
VAMP5 vesicle-associated membrane protein 5
ZNF235 zinc finger protein 235

decreased expression

Symbol Name
ABI3BP ABI family, member 3 (NESH) binding protein
ACADS acyl-CoA dehydrogenase, C-2 to C-3 short chain
ADH7 alcohol dehydrogenase 7 (class IV), mu or sigma polypeptide
AKAP5 A kinase (PRKA) anchor protein 5
ANKFY1 ankyrin repeat and FYVE domain containing 1
ARHGEF28 Rho guanine nucleotide exchange factor (GEF) 28
ARID3B AT rich interactive domain 3B (BRIGHT-like)
ARMC4 armadillo repeat containing 4
AUH AU RNA binding protein/enoyl-CoA hydratase
BCHE butyrylcholinesterase
BIRC7 baculoviral IAP repeat containing 7
C8ORF44 chromosome 8 open reading frame 44
CAMK4 calcium/calmodulin-dependent protein kinase IV
CBL Cbl proto-oncogene, E3 ubiquitin protein ligase
CBS cystathionine-beta-synthase
CCNJL cyclin J-like
CD79B CD79b molecule, immunoglobulin-associated beta
CDADC1 cytidine and dCMP deaminase domain containing 1
CHM choroideremia (Rab escort protein 1)
CIDEC cell death-inducing DFFA-like effector c
CPZ carboxypeptidase Z
CYBRD1 cytochrome b reductase 1
DENND2D DENN/MADD domain containing 2D
ENOX1 ecto-NOX disulfide-thiol exchanger 1
FGL1 fibrinogen-like 1
FKBP10 FK506 binding protein 10, 65 kDa
FMO4 flavin containing monooxygenase 4
G6PD glucose-6-phosphate dehydrogenase
GDAP1 ganglioside induced differentiation associated protein 1
GNG7 guanine nucleotide binding protein (G protein), gamma 7
HAAO 3-hydroxyanthranilate 3,4-dioxygenase
HIST1H2AL histone cluster 1, H2al
HIST1H4D histone cluster 1, H4d
HNRNPA3P1 heterogeneous nuclear ribonucleoprotein A3 pseudogene 1
HOXA1 homeobox A1
HOXC11 homeobox C11
IDI2-AS1 IDI2 antisense RNA 1
IFNA17 interferon, alpha 17
IL17RB interleukin 17 receptor B
IL22 interleukin 22
KCNJ2 potassium channel, inwardly rectifying subfamily J, member 2
KIAA1107 KIAA1107
KIFC1 kinesin family member C1
LIMD2 LIM domain containing 2
LMCD1 LIM and cysteine-rich domains 1
LSM14B LSM14B, SCD6 homolog B (S. cerevisiae)
LY86 lymphocyte antigen 86
MOCS3 molybdenum cofactor synthesis 3
MRM1 mitochondrial rRNA methyltransferase 1 homolog (S. cerevisiae)
MRPS18C mitochondrial ribosomal protein S18C
NBEAL2 neurobeachin-like 2
NEK11 NIMA-related kinase 11
NEURL1 neuralized E3 ubiquitin protein ligase 1
NKX3-2 NK3 homeobox 2
NOD1 nucleotide-binding oligomerization domain containing 1
NPM3 nucleophosmin/nucleoplasmin 3
OR12D2 olfactory receptor, family 12, subfamily D, member 2 (gene/pseudogene)
OSGIN1 oxidative stress induced growth inhibitor 1
OSMR oncostatin M receptor
PAFAH1B2 platelet-activating factor acetylhydrolase 1b, catalytic subunit 2 (30kDa)
PAX9 paired box 9
PDPR pyruvate dehydrogenase phosphatase regulatory subunit
PIN1P1 peptidylprolyl cis/trans isomerase, NIMA-interacting 1 pseudogene 1
PIP prolactin-induced protein
PQLC2 PQ loop repeat containing 2
PRPH peripherin
PTPRS protein tyrosine phosphatase, receptor type, S
R3HCC1L R3H domain and coiled-coil containing 1-like
RABEP1 rabaptin, RAB GTPase binding effector protein 1
RAC3 ras-related C3 botulinum toxin substrate 3 (rho family, small GTP binding protein Rac3)
RFPL3 ret finger protein-like 3
RNF122 ring finger protein 122
RUNX1-IT1 RUNX1 intronic transcript 1
SCIN scinderin
SCNN1B sodium channel, non voltage gated 1 beta subunit
SLC39A1 solute carrier family 39 (zinc transporter), member 1
SLC4A8 solute carrier family 4, sodium bicarbonate cotransporter, member 8
SLC6A9 solute carrier family 6 (neurotransmitter transporter, glycine), member 9
SLC9A5 solute carrier family 9, subfamily A (NHE5, cation proton antiporter 5), member 5
SLITRK5 SLIT and NTRK-like family, member 5
STXBP5L syntaxin binding protein 5-like
TAOK1 TAO kinase 1
TLR2 toll-like receptor 2
TPCN1 two pore segment channel 1
TRAF4 TNF receptor-associated factor 4
TRIM25 tripartite motif containing 25
TRIM66 tripartite motif containing 66
UNC93B1 unc-93 homolog B1 (C. elegans)
USP27X ubiquitin specific peptidase 27, X-linked
VEZT vezatin, adherens junctions transmembrane protein
ZNF141 zinc finger protein 141
ZNF268 zinc finger protein 268
ZNF415 zinc finger protein 415
ZNF480 zinc finger protein 480
ZNF510 zinc finger protein 510
ZNF639 zinc finger protein 639
ZNF747 zinc finger protein 747
ZNF76 zinc finger protein 76