0317956-0000-3777 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

197 genes differentially expressed following the 0317956-0000-3777 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ABCC2 ATP-binding cassette, sub-family C (CFTR/MRP), member 2
ACE angiotensin I converting enzyme
AGPAT4 1-acylglycerol-3-phosphate O-acyltransferase 4
APPBP2 amyloid beta precursor protein (cytoplasmic tail) binding protein 2
ATP10A ATPase, class V, type 10A
BTF3P11 basic transcription factor 3 pseudogene 11
C1S complement component 1, s subcomponent
CAPZB capping protein (actin filament) muscle Z-line, beta
CCNK cyclin K
CCR2 chemokine (C-C motif) receptor 2
CD200 CD200 molecule
CD6 CD6 molecule
CRYGC crystallin, gamma C
CXCL12 chemokine (C-X-C motif) ligand 12
CYP2A6 cytochrome P450, family 2, subfamily A, polypeptide 6
CYTH4 cytohesin 4
DNPEP aspartyl aminopeptidase
DOCK10 dedicator of cytokinesis 10
DOCK5 dedicator of cytokinesis 5
DRD2 dopamine receptor D2
DTNB dystrobrevin, beta
ELAC1 elaC ribonuclease Z 1
ELAVL3 ELAV like neuron-specific RNA binding protein 3
EXOSC2 exosome component 2
FAM174B family with sequence similarity 174, member B
FBXO24 F-box protein 24
FCGR2C Fc fragment of IgG, low affinity IIc, receptor for (CD32) (gene/pseudogene)
FGF18 fibroblast growth factor 18
FGF22 fibroblast growth factor 22
FLT1 fms-related tyrosine kinase 1
GRB7 growth factor receptor-bound protein 7
GRM7 glutamate receptor, metabotropic 7
GSN-AS1 GSN antisense RNA 1
GTPBP1 GTP binding protein 1
HCN4 hyperpolarization activated cyclic nucleotide gated potassium channel 4
HEYL hes-related family bHLH transcription factor with YRPW motif-like
HIST1H3A histone cluster 1, H3a
HNF4A hepatocyte nuclear factor 4, alpha
HPSE2 heparanase 2 (inactive)
IBSP integrin-binding sialoprotein
IFITM1 interferon induced transmembrane protein 1
IL32 interleukin 32
IL36G interleukin 36, gamma
KCNJ5 potassium channel, inwardly rectifying subfamily J, member 5
KERA keratocan
KIAA1549L KIAA1549-like
KIR2DL1 killer cell immunoglobulin-like receptor, two domains, long cytoplasmic tail, 1
LLGL1 lethal giant larvae homolog 1 (Drosophila)
LOC100294391 uncharacterized LOC100294391
LOC399491
LPP LIM domain containing preferred translocation partner in lipoma
MAN1C1 mannosidase, alpha, class 1C, member 1
MCF2L MCF.2 cell line derived transforming sequence-like
MEOX2 mesenchyme homeobox 2
METTL7A methyltransferase like 7A
MMP13 matrix metallopeptidase 13
MT3 metallothionein 3
MYO15A myosin XVA
NPRL2 nitrogen permease regulator-like 2 (S. cerevisiae)
NPTX1 neuronal pentraxin I
NPY6R neuropeptide Y receptor Y6 (pseudogene)
NTRK1 neurotrophic tyrosine kinase, receptor, type 1
PAOX polyamine oxidase (exo-N4-amino)
PCDHB1 protocadherin beta 1
PDE10A phosphodiesterase 10A
PDLIM3 PDZ and LIM domain 3
PRDM1 PR domain containing 1, with ZNF domain
PRM1 protamine 1
PSORS1C1 psoriasis susceptibility 1 candidate 1
PTPN21 protein tyrosine phosphatase, non-receptor type 21
RDH5 retinol dehydrogenase 5 (11-cis/9-cis)
RNF208 ring finger protein 208
RPL7 ribosomal protein L7
RPS4Y1 ribosomal protein S4, Y-linked 1
RUNDC3A RUN domain containing 3A
SELL selectin L
SEMA5A sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5A
SERHL2 serine hydrolase-like 2
SLC14A1 solute carrier family 14 (urea transporter), member 1 (Kidd blood group)
SLC2A11 solute carrier family 2 (facilitated glucose transporter), member 11
SLC6A20 solute carrier family 6 (proline IMINO transporter), member 20
SMR3A submaxillary gland androgen regulated protein 3A
SNCA synuclein, alpha (non A4 component of amyloid precursor)
SND1-IT1 SND1 intronic transcript 1
SP110 SP110 nuclear body protein
ST6GAL1 ST6 beta-galactosamide alpha-2,6-sialyltranferase 1
ST8SIA4 ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 4
STK24 serine/threonine kinase 24
TEF thyrotrophic embryonic factor
TEX14 testis expressed 14
TM4SF5 transmembrane 4 L six family member 5
TNFRSF13B tumor necrosis factor receptor superfamily, member 13B
TPM3 tropomyosin 3
TRA2A transformer 2 alpha homolog (Drosophila)
TTN titin
TUBB1 tubulin, beta 1 class VI
UTP14A UTP14, U3 small nucleolar ribonucleoprotein, homolog A (yeast)
VAC14 Vac14 homolog (S. cerevisiae)
VHL von Hippel-Lindau tumor suppressor, E3 ubiquitin protein ligase

decreased expression

Symbol Name
ABL2 ABL proto-oncogene 2, non-receptor tyrosine kinase
ACSS3 acyl-CoA synthetase short-chain family member 3
ADAM23 ADAM metallopeptidase domain 23
AKAP5 A kinase (PRKA) anchor protein 5
ANXA10 annexin A10
AOC2 amine oxidase, copper containing 2 (retina-specific)
APBB1 amyloid beta (A4) precursor protein-binding, family B, member 1 (Fe65)
ARHGEF1 Rho guanine nucleotide exchange factor (GEF) 1
ARMCX2 armadillo repeat containing, X-linked 2
ASPSCR1 alveolar soft part sarcoma chromosome region, candidate 1
ATP8B2 ATPase, aminophospholipid transporter, class I, type 8B, member 2
B9D2 B9 protein domain 2
BIRC7 baculoviral IAP repeat containing 7
C17ORF53 chromosome 17 open reading frame 53
C19ORF40 chromosome 19 open reading frame 40
C1ORF21 chromosome 1 open reading frame 21
C5 complement component 5
CAMK4 calcium/calmodulin-dependent protein kinase IV
CAMKMT calmodulin-lysine N-methyltransferase
CCDC134 coiled-coil domain containing 134
CDK20 cyclin-dependent kinase 20
CDKL3 cyclin-dependent kinase-like 3
CGREF1 cell growth regulator with EF-hand domain 1
CLIC3 chloride intracellular channel 3
CYB5R2 cytochrome b5 reductase 2
CYP39A1 cytochrome P450, family 39, subfamily A, polypeptide 1
DCAF13 DDB1 and CUL4 associated factor 13
DEPTOR DEP domain containing MTOR-interacting protein
DHRS9 dehydrogenase/reductase (SDR family) member 9
DNAH7 dynein, axonemal, heavy chain 7
EFCAB2 EF-hand calcium binding domain 2
FBRS fibrosin
FGL1 fibrinogen-like 1
GCNT2 glucosaminyl (N-acetyl) transferase 2, I-branching enzyme (I blood group)
GCNT3 glucosaminyl (N-acetyl) transferase 3, mucin type
GK3P glycerol kinase 3 pseudogene
HDAC7 histone deacetylase 7
HIST1H2AB histone cluster 1, H2ab
HIST1H2AL histone cluster 1, H2al
IL22 interleukin 22
IL7 interleukin 7
INO80D INO80 complex subunit D
KCNJ2 potassium channel, inwardly rectifying subfamily J, member 2
KPTN kaptin (actin binding protein)
KRT4 keratin 4, type II
KRT86 keratin 86, type II
LIMD2 LIM domain containing 2
LMTK2 lemur tyrosine kinase 2
LPPR4 lipid phosphate phosphatase-related protein type 4
LRRC37A4P leucine rich repeat containing 37, member A4, pseudogene
LSM14B LSM14B, SCD6 homolog B (S. cerevisiae)
MOCS3 molybdenum cofactor synthesis 3
MRM1 mitochondrial rRNA methyltransferase 1 homolog (S. cerevisiae)
MRPS18C mitochondrial ribosomal protein S18C
MTA2 metastasis associated 1 family, member 2
MYLIP myosin regulatory light chain interacting protein
NELL2 NEL-like 2 (chicken)
NOL10 nucleolar protein 10
NPM3 nucleophosmin/nucleoplasmin 3
OPA3 optic atrophy 3 (autosomal recessive, with chorea and spastic paraplegia)
P2RY1 purinergic receptor P2Y, G-protein coupled, 1
PAK3 p21 protein (Cdc42/Rac)-activated kinase 3
PGP phosphoglycolate phosphatase
PIN1P1 peptidylprolyl cis/trans isomerase, NIMA-interacting 1 pseudogene 1
PODXL2 podocalyxin-like 2
PRSS53 protease, serine, 53
RANBP17 RAN binding protein 17
RBMS3 RNA binding motif, single stranded interacting protein 3
RHOBTB2 Rho-related BTB domain containing 2
RHPN1-AS1 RHPN1 antisense RNA 1 (head to head)
RIMS3 regulating synaptic membrane exocytosis 3
RNF2 ring finger protein 2
RNF43 ring finger protein 43
ROGDI rogdi homolog (Drosophila)
S100A3 S100 calcium binding protein A3
SLC4A3 solute carrier family 4 (anion exchanger), member 3
SLC6A9 solute carrier family 6 (neurotransmitter transporter, glycine), member 9
SLMO1 slowmo homolog 1 (Drosophila)
SNAPC2 small nuclear RNA activating complex, polypeptide 2, 45kDa
TBX19 T-box 19
THRB thyroid hormone receptor, beta
TMEM183A transmembrane protein 183A
TMEM209 transmembrane protein 209
TOM1 target of myb1 (chicken)
TRAF4 TNF receptor-associated factor 4
TSC22D4 TSC22 domain family, member 4
TSPAN32 tetraspanin 32
TTC30A tetratricopeptide repeat domain 30A
TUBA4B tubulin, alpha 4b
UNC119 unc-119 homolog (C. elegans)
WT1-AS WT1 antisense RNA
YIF1B Yip1 interacting factor homolog B (S. cerevisiae)
ZBTB6 zinc finger and BTB domain containing 6
ZNF205 zinc finger protein 205
ZNF214 zinc finger protein 214
ZNF37BP zinc finger protein 37B, pseudogene
ZNF480 zinc finger protein 480
ZNF767P zinc finger family member 767, pseudogene