0317956-0000-3855 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

197 genes differentially expressed following the 0317956-0000-3855 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
AGAP2 ArfGAP with GTPase domain, ankyrin repeat and PH domain 2
AKAP8L A kinase (PRKA) anchor protein 8-like
AQP3 aquaporin 3 (Gill blood group)
ATN1 atrophin 1
ATP10A ATPase, class V, type 10A
ATP10D ATPase, class V, type 10D
ATP11A ATPase, class VI, type 11A
BCL2L10 BCL2-like 10 (apoptosis facilitator)
BMP10 bone morphogenetic protein 10
BTG2 BTG family, member 2
CACNA1D calcium channel, voltage-dependent, L type, alpha 1D subunit
CACNB2 calcium channel, voltage-dependent, beta 2 subunit
CASP2 caspase 2, apoptosis-related cysteine peptidase
CBL Cbl proto-oncogene, E3 ubiquitin protein ligase
CERS4 ceramide synthase 4
CFHR4 complement factor H-related 4
CLTC clathrin, heavy chain (Hc)
COL2A1 collagen, type II, alpha 1
CPQ carboxypeptidase Q
CTNS cystinosin, lysosomal cystine transporter
CTRL chymotrypsin-like
CUZD1 CUB and zona pellucida-like domains 1
CYP1A1 cytochrome P450, family 1, subfamily A, polypeptide 1
CYP1B1 cytochrome P450, family 1, subfamily B, polypeptide 1
DAPK3 death-associated protein kinase 3
DFNB31 deafness, autosomal recessive 31
DIXDC1 DIX domain containing 1
DNAJC28 DnaJ (Hsp40) homolog, subfamily C, member 28
EMC3 ER membrane protein complex subunit 3
GPER1 G protein-coupled estrogen receptor 1
GPR176 G protein-coupled receptor 176
GSN gelsolin
GSTA1 glutathione S-transferase alpha 1
HFE hemochromatosis
HLF hepatic leukemia factor
HNRNPUL2 heterogeneous nuclear ribonucleoprotein U-like 2
HPX hemopexin
HS6ST1 heparan sulfate 6-O-sulfotransferase 1
IGFBP3 insulin-like growth factor binding protein 3
IL6ST interleukin 6 signal transducer
INPP4A inositol polyphosphate-4-phosphatase, type I, 107kDa
KIAA0319L KIAA0319-like
KITLG KIT ligand
KLHL24 kelch-like family member 24
KMT2A lysine (K)-specific methyltransferase 2A
LSS lanosterol synthase (2,3-oxidosqualene-lanosterol cyclase)
MED25 mediator complex subunit 25
MFGE8 milk fat globule-EGF factor 8 protein
MMP16 matrix metallopeptidase 16 (membrane-inserted)
MR1 major histocompatibility complex, class I-related
NDRG2 NDRG family member 2
NEAT1 nuclear paraspeckle assembly transcript 1 (non-protein coding)
NGLY1 N-glycanase 1
NIPAL3 NIPA-like domain containing 3
NUP188 nucleoporin 188kDa
OSBPL7 oxysterol binding protein-like 7
PAIP2B poly(A) binding protein interacting protein 2B
PCDHGC3 protocadherin gamma subfamily C, 3
PDAP1 PDGFA associated protein 1
PGLYRP4 peptidoglycan recognition protein 4
PIK3IP1 phosphoinositide-3-kinase interacting protein 1
PKNOX1 PBX/knotted 1 homeobox 1
PLXNB3 plexin B3
POU5F1B POU class 5 homeobox 1B
PSCA prostate stem cell antigen
R3HCC1L R3H domain and coiled-coil containing 1-like
RAC3 ras-related C3 botulinum toxin substrate 3 (rho family, small GTP binding protein Rac3)
RBM5 RNA binding motif protein 5
RUNDC3B RUN domain containing 3B
RXRB retinoid X receptor, beta
SENP7 SUMO1/sentrin specific peptidase 7
SFI1 Sfi1 homolog, spindle assembly associated (yeast)
SIRPA signal-regulatory protein alpha
SLC16A3 solute carrier family 16 (monocarboxylate transporter), member 3
SLCO4C1 solute carrier organic anion transporter family, member 4C1
SOX2 SRY (sex determining region Y)-box 2
SPPL2B signal peptide peptidase like 2B
SPTLC2 serine palmitoyltransferase, long chain base subunit 2
SRCAP Snf2-related CREBBP activator protein
SRF serum response factor (c-fos serum response element-binding transcription factor)
SSX3 synovial sarcoma, X breakpoint 3
ST3GAL4 ST3 beta-galactoside alpha-2,3-sialyltransferase 4
STK4 serine/threonine kinase 4
TBC1D22B TBC1 domain family, member 22B
TCN1 transcobalamin I (vitamin B12 binding protein, R binder family)
TLE1 transducin-like enhancer of split 1 (E(sp1) homolog, Drosophila)
TNFRSF25 tumor necrosis factor receptor superfamily, member 25
TP53I11 tumor protein p53 inducible protein 11
TRAF4 TNF receptor-associated factor 4
TRIM29 tripartite motif containing 29
TSC22D3 TSC22 domain family, member 3
TTC38 tetratricopeptide repeat domain 38
UROD uroporphyrinogen decarboxylase
VAV2 vav 2 guanine nucleotide exchange factor
WSB1 WD repeat and SOCS box containing 1
ZER1 zyg-11 related, cell cycle regulator
ZFP36L1 ZFP36 ring finger protein-like 1
ZNF230 zinc finger protein 230
ZSWIM1 zinc finger, SWIM-type containing 1

decreased expression

Symbol Name
ACTL8 actin-like 8
ARMC4 armadillo repeat containing 4
B3GALT4 UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 4
B3GNT4 UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 4
C11ORF21 chromosome 11 open reading frame 21
C19ORF73 chromosome 19 open reading frame 73
C2CD2 C2 calcium-dependent domain containing 2
C3 complement component 3
C4BPA complement component 4 binding protein, alpha
CALHM2 calcium homeostasis modulator 2
CDK3 cyclin-dependent kinase 3
CTNNB1 catenin (cadherin-associated protein), beta 1, 88kDa
DUSP13 dual specificity phosphatase 13
DUSP4 dual specificity phosphatase 4
DUSP5 dual specificity phosphatase 5
EEF2KMT eukaryotic elongation factor 2 lysine methyltransferase
EGFL7 EGF-like-domain, multiple 7
EGR3 early growth response 3
ELP6 elongator acetyltransferase complex subunit 6
EMID1 EMI domain containing 1
ENOX1 ecto-NOX disulfide-thiol exchanger 1
EPHA2 EPH receptor A2
ETNK2 ethanolamine kinase 2
FAM155A family with sequence similarity 155, member A
FAM76A family with sequence similarity 76, member A
FFAR2 free fatty acid receptor 2
FGF4 fibroblast growth factor 4
FLJ22184
FOSL1 FOS-like antigen 1
FOXI1 forkhead box I1
FURIN furin (paired basic amino acid cleaving enzyme)
FXYD5 FXYD domain containing ion transport regulator 5
GAMT guanidinoacetate N-methyltransferase
GMPR guanosine monophosphate reductase
GNAT2 guanine nucleotide binding protein (G protein), alpha transducing activity polypeptide 2
GNG4 guanine nucleotide binding protein (G protein), gamma 4
GPR21 G protein-coupled receptor 21
HDAC4 histone deacetylase 4
HDAC7 histone deacetylase 7
HIST1H1B histone cluster 1, H1b
HIST1H4C histone cluster 1, H4c
HIST1H4D histone cluster 1, H4d
HOXC11 homeobox C11
HOXC5 homeobox C5
HTR1E 5-hydroxytryptamine (serotonin) receptor 1E, G protein-coupled
IFNA14 interferon, alpha 14
INPP5J inositol polyphosphate-5-phosphatase J
KIF13B kinesin family member 13B
KLK5 kallikrein-related peptidase 5
LARP6 La ribonucleoprotein domain family, member 6
LHX1 LIM homeobox 1
LIF leukemia inhibitory factor
LOXL3 lysyl oxidase-like 3
MALL mal, T-cell differentiation protein-like
MED15 mediator complex subunit 15
MMP15 matrix metallopeptidase 15 (membrane-inserted)
MMP3 matrix metallopeptidase 3
MTA2 metastasis associated 1 family, member 2
MYBBP1A MYB binding protein (P160) 1a
MYLPF myosin light chain, phosphorylatable, fast skeletal muscle
NAV2 neuron navigator 2
NPPA natriuretic peptide A
NXPH4 neurexophilin 4
OR7E47P olfactory receptor, family 7, subfamily E, member 47 pseudogene
OVOL1 ovo-like zinc finger 1
PFKFB3 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3
PGBD5 piggyBac transposable element derived 5
PLEKHS1 pleckstrin homology domain containing, family S member 1
PPP2R3B protein phosphatase 2, regulatory subunit B'', beta
PREX2 phosphatidylinositol-3,4,5-trisphosphate-dependent Rac exchange factor 2
PTPRCAP protein tyrosine phosphatase, receptor type, C-associated protein
PTPRE protein tyrosine phosphatase, receptor type, E
RAB36 RAB36, member RAS oncogene family
RAB3IL1 RAB3A interacting protein (rabin3)-like 1
RAI14 retinoic acid induced 14
RASGRP1 RAS guanyl releasing protein 1 (calcium and DAG-regulated)
RCN1 reticulocalbin 1, EF-hand calcium binding domain
RELN reelin
RNPEPL1 arginyl aminopeptidase (aminopeptidase B)-like 1
RSPH14 radial spoke head 14 homolog (Chlamydomonas)
SDC3 syndecan 3
SIDT1 SID1 transmembrane family, member 1
SIPA1 signal-induced proliferation-associated 1
SOWAHC sosondowah ankyrin repeat domain family member C
SPRED2 sprouty-related, EVH1 domain containing 2
SSR3 signal sequence receptor, gamma (translocon-associated protein gamma)
ST5 suppression of tumorigenicity 5
TCP10 t-complex 10
TLR2 toll-like receptor 2
TNS3 tensin 3
TRIM68 tripartite motif containing 68
TRPV1 transient receptor potential cation channel, subfamily V, member 1
VIPR1 vasoactive intestinal peptide receptor 1
ZAK sterile alpha motif and leucine zipper containing kinase AZK
ZFHX2 zinc finger homeobox 2
ZMAT4 zinc finger, matrin-type 4
ZNF358 zinc finger protein 358
ZNF365 zinc finger protein 365