0317956-0000-3858 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

196 genes differentially expressed following the 0317956-0000-3858 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
A4GALT alpha 1,4-galactosyltransferase
AIF1 allograft inflammatory factor 1
AKAP4 A kinase (PRKA) anchor protein 4
ALDOB aldolase B, fructose-bisphosphate
AQP3 aquaporin 3 (Gill blood group)
BTG2 BTG family, member 2
C1QL1 complement component 1, q subcomponent-like 1
CASP1 caspase 1, apoptosis-related cysteine peptidase
CEACAM7 carcinoembryonic antigen-related cell adhesion molecule 7
CEP250 centrosomal protein 250kDa
CFLAR CASP8 and FADD-like apoptosis regulator
CLDN17 claudin 17
CLIP2 CAP-GLY domain containing linker protein 2
COL1A1 collagen, type I, alpha 1
COL6A2 collagen, type VI, alpha 2
COPA coatomer protein complex, subunit alpha
CPA4 carboxypeptidase A4
CPQ carboxypeptidase Q
CPSF1 cleavage and polyadenylation specific factor 1, 160kDa
CTIF CBP80/20-dependent translation initiation factor
CYP1A1 cytochrome P450, family 1, subfamily A, polypeptide 1
DAPK3 death-associated protein kinase 3
DST dystonin
EDN1 endothelin 1
ELAVL3 ELAV like neuron-specific RNA binding protein 3
ESR1 estrogen receptor 1
FBXO4 F-box protein 4
FGFR2 fibroblast growth factor receptor 2
FKRP fukutin related protein
FLOT1 flotillin 1
FSCN1 fascin actin-bundling protein 1
FSHB follicle stimulating hormone, beta polypeptide
FUS FUS RNA binding protein
GBP1 guanylate binding protein 1, interferon-inducible
GGA2 golgi-associated, gamma adaptin ear containing, ARF binding protein 2
GGT1 gamma-glutamyltransferase 1
GLYR1 glyoxylate reductase 1 homolog (Arabidopsis)
GPER1 G protein-coupled estrogen receptor 1
GSN gelsolin
GTPBP1 GTP binding protein 1
HTATSF1 HIV-1 Tat specific factor 1
IFT27 intraflagellar transport 27
IGFBP3 insulin-like growth factor binding protein 3
IL6ST interleukin 6 signal transducer
ITGAM integrin, alpha M (complement component 3 receptor 3 subunit)
JAK2 Janus kinase 2
KHK ketohexokinase (fructokinase)
KIF24 kinesin family member 24
KITLG KIT ligand
KLHL22 kelch-like family member 22
KRT9 keratin 9, type I
LATS1 large tumor suppressor kinase 1
LSP1 lymphocyte-specific protein 1
LSS lanosterol synthase (2,3-oxidosqualene-lanosterol cyclase)
MAF v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog
MEF2C myocyte enhancer factor 2C
MET MET proto-oncogene, receptor tyrosine kinase
MMP11 matrix metallopeptidase 11
MOBP myelin-associated oligodendrocyte basic protein
MTHFR methylenetetrahydrofolate reductase (NAD(P)H)
NDRG2 NDRG family member 2
NEAT1 nuclear paraspeckle assembly transcript 1 (non-protein coding)
NEK1 NIMA-related kinase 1
NKTR natural killer cell triggering receptor
NPHS1 nephrosis 1, congenital, Finnish type (nephrin)
NPR1 natriuretic peptide receptor 1
OGFR opioid growth factor receptor
PDE3B phosphodiesterase 3B, cGMP-inhibited
POM121 POM121 transmembrane nucleoporin
PTPRA protein tyrosine phosphatase, receptor type, A
PVR poliovirus receptor
RAC3 ras-related C3 botulinum toxin substrate 3 (rho family, small GTP binding protein Rac3)
RASA3 RAS p21 protein activator 3
RB1 retinoblastoma 1
RBL2 retinoblastoma-like 2
RBM5 RNA binding motif protein 5
RBP4 retinol binding protein 4, plasma
REM1 RAS (RAD and GEM)-like GTP-binding 1
RNF6 ring finger protein (C3H2C3 type) 6
RXRB retinoid X receptor, beta
SEMA4G sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4G
SLC16A3 solute carrier family 16 (monocarboxylate transporter), member 3
SP1 Sp1 transcription factor
SRCAP Snf2-related CREBBP activator protein
SRF serum response factor (c-fos serum response element-binding transcription factor)
ST6GAL1 ST6 beta-galactosamide alpha-2,6-sialyltranferase 1
TAS2R1 taste receptor, type 2, member 1
THBS1 thrombospondin 1
TLR5 toll-like receptor 5
TNFRSF25 tumor necrosis factor receptor superfamily, member 25
TRA2A transformer 2 alpha homolog (Drosophila)
TRAF4 TNF receptor-associated factor 4
TULP2 tubby like protein 2
TXNIP thioredoxin interacting protein
U2AF2 U2 small nuclear RNA auxiliary factor 2
UCN urocortin
USP2 ubiquitin specific peptidase 2
VAV2 vav 2 guanine nucleotide exchange factor

decreased expression

Symbol Name
ABHD14A abhydrolase domain containing 14A
ACTL8 actin-like 8
ADAP2 ArfGAP with dual PH domains 2
AMH anti-Mullerian hormone
ARHGAP10 Rho GTPase activating protein 10
ARR3 arrestin 3, retinal (X-arrestin)
B3GNT4 UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 4
C2CD2 C2 calcium-dependent domain containing 2
C4BPA complement component 4 binding protein, alpha
CALHM2 calcium homeostasis modulator 2
CALML5 calmodulin-like 5
CD3EAP CD3e molecule, epsilon associated protein
CDC42EP1 CDC42 effector protein (Rho GTPase binding) 1
CEMIP cell migration inducing protein, hyaluronan binding
CGA glycoprotein hormones, alpha polypeptide
CHST8 carbohydrate (N-acetylgalactosamine 4-0) sulfotransferase 8
CORO7 coronin 7
CTNNB1 catenin (cadherin-associated protein), beta 1, 88kDa
DNAAF2 dynein, axonemal, assembly factor 2
DUSP4 dual specificity phosphatase 4
DYM dymeclin
EGR3 early growth response 3
ELMO3 engulfment and cell motility 3
ELP6 elongator acetyltransferase complex subunit 6
EMID1 EMI domain containing 1
ENOX1 ecto-NOX disulfide-thiol exchanger 1
EPHA2 EPH receptor A2
EPHB6 EPH receptor B6
FAM131A family with sequence similarity 131, member A
FBXL8 F-box and leucine-rich repeat protein 8
FFAR2 free fatty acid receptor 2
FGF23 fibroblast growth factor 23
FLJ22184
FOXC1 forkhead box C1
GDPD5 glycerophosphodiester phosphodiesterase domain containing 5
GEMIN8 gem (nuclear organelle) associated protein 8
GLS2 glutaminase 2 (liver, mitochondrial)
GNA14 guanine nucleotide binding protein (G protein), alpha 14
GPT glutamic-pyruvate transaminase (alanine aminotransferase)
HDAC5 histone deacetylase 5
HIST1H1B histone cluster 1, H1b
HIST1H2AJ histone cluster 1, H2aj
HIST1H4C histone cluster 1, H4c
IER5 immediate early response 5
IFNA14 interferon, alpha 14
IL22 interleukin 22
IRF2BP1 interferon regulatory factor 2 binding protein 1
IRF7 interferon regulatory factor 7
ITGA3 integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor)
KBTBD11 kelch repeat and BTB (POZ) domain containing 11
KDM8 lysine (K)-specific demethylase 8
KIAA0355 KIAA0355
KIF13A kinesin family member 13A
KLF3 Kruppel-like factor 3 (basic)
KREMEN2 kringle containing transmembrane protein 2
LARP6 La ribonucleoprotein domain family, member 6
LIF leukemia inhibitory factor
LMNB1 lamin B1
LRP5 low density lipoprotein receptor-related protein 5
MAN2C1 mannosidase, alpha, class 2C, member 1
MMP15 matrix metallopeptidase 15 (membrane-inserted)
MRPL52 mitochondrial ribosomal protein L52
MYBBP1A MYB binding protein (P160) 1a
NAV2 neuron navigator 2
NOD1 nucleotide-binding oligomerization domain containing 1
NXPH4 neurexophilin 4
PFKFB3 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3
PGPEP1 pyroglutamyl-peptidase I
PLA2G3 phospholipase A2, group III
PLCD1 phospholipase C, delta 1
PLEK2 pleckstrin 2
PLEKHO2 pleckstrin homology domain containing, family O member 2
PLEKHS1 pleckstrin homology domain containing, family S member 1
POLL polymerase (DNA directed), lambda
PTPRE protein tyrosine phosphatase, receptor type, E
PYCRL pyrroline-5-carboxylate reductase-like
RAB36 RAB36, member RAS oncogene family
RASGRP1 RAS guanyl releasing protein 1 (calcium and DAG-regulated)
RIBC2 RIB43A domain with coiled-coils 2
S100A9 S100 calcium binding protein A9
SHARPIN SHANK-associated RH domain interactor
SIDT1 SID1 transmembrane family, member 1
SLC43A1 solute carrier family 43 (amino acid system L transporter), member 1
SPRY2 sprouty homolog 2 (Drosophila)
SSR3 signal sequence receptor, gamma (translocon-associated protein gamma)
STAG3L4 stromal antigen 3-like 4 (pseudogene)
TGFBI transforming growth factor, beta-induced, 68kDa
TRABD TraB domain containing
TUBA3C tubulin, alpha 3c
TUBA4B tubulin, alpha 4b
TUT1 terminal uridylyl transferase 1, U6 snRNA-specific
XAB2 XPA binding protein 2
ZMAT4 zinc finger, matrin-type 4
ZNF358 zinc finger protein 358
ZNF365 zinc finger protein 365
ZNF442 zinc finger protein 442
ZNF532 zinc finger protein 532
ZNF747 zinc finger protein 747