0317956-0000-3966 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

198 genes differentially expressed following the 0317956-0000-3966 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ACSBG1 acyl-CoA synthetase bubblegum family member 1
ADGRA2 adhesion G protein-coupled receptor A2
ADORA3 adenosine A3 receptor
AKAP5 A kinase (PRKA) anchor protein 5
ALDH1L1 aldehyde dehydrogenase 1 family, member L1
ANO2 anoctamin 2, calcium activated chloride channel
APCS amyloid P component, serum
APOC1 apolipoprotein C-I
ATF7IP activating transcription factor 7 interacting protein
ATP10A ATPase, class V, type 10A
C1ORF95 chromosome 1 open reading frame 95
C5AR1 complement component 5a receptor 1
C9ORF156 chromosome 9 open reading frame 156
CALCR calcitonin receptor
CAMK2B calcium/calmodulin-dependent protein kinase II beta
CAPN2 calpain 2, (m/II) large subunit
CD70 CD70 molecule
CD79A CD79a molecule, immunoglobulin-associated alpha
CDC25C cell division cycle 25C
CDH18 cadherin 18, type 2
COL1A1 collagen, type I, alpha 1
COL4A2 collagen, type IV, alpha 2
CR1 complement component (3b/4b) receptor 1 (Knops blood group)
CYP1A1 cytochrome P450, family 1, subfamily A, polypeptide 1
DENND2A DENN/MADD domain containing 2A
DFNB31 deafness, autosomal recessive 31
DMWD dystrophia myotonica, WD repeat containing
DOK2 docking protein 2, 56kDa
ETV1 ets variant 1
FGFR1 fibroblast growth factor receptor 1
FN1 fibronectin 1
FST follistatin
GABARAPL1 GABA(A) receptor-associated protein like 1
GABRR2 gamma-aminobutyric acid (GABA) A receptor, rho 2
GGA1 golgi-associated, gamma adaptin ear containing, ARF binding protein 1
GPER1 G protein-coupled estrogen receptor 1
GZMK granzyme K (granzyme 3; tryptase II)
HIST1H3I histone cluster 1, H3i
HUWE1 HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase
IFIT3 interferon-induced protein with tetratricopeptide repeats 3
INHBE inhibin, beta E
KCNJ4 potassium channel, inwardly rectifying subfamily J, member 4
KIF25 kinesin family member 25
KLRB1 killer cell lectin-like receptor subfamily B, member 1
KRT8 keratin 8, type II
L3MBTL1 l(3)mbt-like 1 (Drosophila)
LIME1 Lck interacting transmembrane adaptor 1
LINC00312 long intergenic non-protein coding RNA 312
LINC00341 long intergenic non-protein coding RNA 341
LY6H lymphocyte antigen 6 complex, locus H
MC5R melanocortin 5 receptor
MEFV Mediterranean fever
MEG3 maternally expressed 3 (non-protein coding)
MINK1 misshapen-like kinase 1
MLN motilin
MST1R macrophage stimulating 1 receptor
MTHFR methylenetetrahydrofolate reductase (NAD(P)H)
MUC2 mucin 2, oligomeric mucus/gel-forming
NEUROD1 neuronal differentiation 1
NPHP1 nephronophthisis 1 (juvenile)
NR6A1 nuclear receptor subfamily 6, group A, member 1
NUPR1 nuclear protein, transcriptional regulator, 1
OR1E1 olfactory receptor, family 1, subfamily E, member 1
OSBPL7 oxysterol binding protein-like 7
PAX8 paired box 8
PCDHB11 protocadherin beta 11
PDGFRA platelet-derived growth factor receptor, alpha polypeptide
PMS2P3 postmeiotic segregation increased 2 pseudogene 3
PNPLA4 patatin-like phospholipase domain containing 4
PPARD peroxisome proliferator-activated receptor delta
PRDM14 PR domain containing 14
PRKD1 protein kinase D1
PTAFR platelet-activating factor receptor
PTCH1 patched 1
RUNDC3B RUN domain containing 3B
SCNN1G sodium channel, non voltage gated 1 gamma subunit
SEPP1 selenoprotein P, plasma, 1
SERHL2 serine hydrolase-like 2
SERPINB13 serpin peptidase inhibitor, clade B (ovalbumin), member 13
SLC10A2 solute carrier family 10 (sodium/bile acid cotransporter), member 2
SPEG SPEG complex locus
SPRR2B small proline-rich protein 2B
STIM1 stromal interaction molecule 1
STON1 stonin 1
SUGP1 SURP and G patch domain containing 1
TAS2R4 taste receptor, type 2, member 4
TEX14 testis expressed 14
TFEB transcription factor EB
TGFA transforming growth factor, alpha
THAP3 THAP domain containing, apoptosis associated protein 3
THY1 Thy-1 cell surface antigen
TMEM40 transmembrane protein 40
TMOD1 tropomodulin 1
TRAPPC9 trafficking protein particle complex 9
TREM1 triggering receptor expressed on myeloid cells 1
TRH thyrotropin-releasing hormone
UPF3A UPF3 regulator of nonsense transcripts homolog A (yeast)
WRNIP1 Werner helicase interacting protein 1
XPNPEP1 X-prolyl aminopeptidase (aminopeptidase P) 1, soluble

decreased expression

Symbol Name
ABCA7 ATP-binding cassette, sub-family A (ABC1), member 7
ADAMTS13 ADAM metallopeptidase with thrombospondin type 1 motif, 13
ADAP2 ArfGAP with dual PH domains 2
AEN apoptosis enhancing nuclease
AHSP alpha hemoglobin stabilizing protein
AP1S1 adaptor-related protein complex 1, sigma 1 subunit
ARHGAP29 Rho GTPase activating protein 29
BATF basic leucine zipper transcription factor, ATF-like
BMP10 bone morphogenetic protein 10
BRINP2 bone morphogenetic protein/retinoic acid inducible neural-specific 2
C14ORF79 chromosome 14 open reading frame 79
C1ORF159 chromosome 1 open reading frame 159
C1QB complement component 1, q subcomponent, B chain
CALHM2 calcium homeostasis modulator 2
CARTPT CART prepropeptide
CCNE1 cyclin E1
CDHR2 cadherin-related family member 2
CDK3 cyclin-dependent kinase 3
CDK6 cyclin-dependent kinase 6
CDKL3 cyclin-dependent kinase-like 3
CEMIP cell migration inducing protein, hyaluronan binding
CEND1 cell cycle exit and neuronal differentiation 1
CORO7 coronin 7
CRIP1 cysteine-rich protein 1 (intestinal)
CUZD1 CUB and zona pellucida-like domains 1
DRD1 dopamine receptor D1
DUSP4 dual specificity phosphatase 4
DUSP5 dual specificity phosphatase 5
EGR3 early growth response 3
EPHA2 EPH receptor A2
ETV6 ets variant 6
FBXL2 F-box and leucine-rich repeat protein 2
FLJ22184
FOSL1 FOS-like antigen 1
GAB2 GRB2-associated binding protein 2
GCNT1 glucosaminyl (N-acetyl) transferase 1, core 2
GCNT2 glucosaminyl (N-acetyl) transferase 2, I-branching enzyme (I blood group)
HNRNPA3P1 heterogeneous nuclear ribonucleoprotein A3 pseudogene 1
HS3ST3A1 heparan sulfate (glucosamine) 3-O-sulfotransferase 3A1
HTR1F 5-hydroxytryptamine (serotonin) receptor 1F, G protein-coupled
IER5 immediate early response 5
IFI6 interferon, alpha-inducible protein 6
IKZF5 IKAROS family zinc finger 5 (Pegasus)
ITGA8 integrin, alpha 8
ITPKB inositol-trisphosphate 3-kinase B
KCNF1 potassium channel, voltage gated modifier subfamily F, member 1
KDM8 lysine (K)-specific demethylase 8
KIAA0754 KIAA0754
KIF13B kinesin family member 13B
KREMEN2 kringle containing transmembrane protein 2
KRT83 keratin 83, type II
MAFF v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog F
MALL mal, T-cell differentiation protein-like
MAP3K1 mitogen-activated protein kinase kinase kinase 1, E3 ubiquitin protein ligase
MOB3B MOB kinase activator 3B
MTCL1 microtubule crosslinking factor 1
MUL1 mitochondrial E3 ubiquitin protein ligase 1
MX2 MX dynamin-like GTPase 2
NAV2 neuron navigator 2
NEUROD4 neuronal differentiation 4
NOTCH4 notch 4
NPTX1 neuronal pentraxin I
NPY neuropeptide Y
OCA2 oculocutaneous albinism II
OR7E156P olfactory receptor, family 7, subfamily E, member 156 pseudogene
OVOL1 ovo-like zinc finger 1
PACS1 phosphofurin acidic cluster sorting protein 1
PFKFB3 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3
PLAC4 placenta-specific 4
PLEKHS1 pleckstrin homology domain containing, family S member 1
PMCHL1 pro-melanin-concentrating hormone-like 1, pseudogene
PSG4 pregnancy specific beta-1-glycoprotein 4
QPCT glutaminyl-peptide cyclotransferase
RAB40C RAB40C, member RAS oncogene family
RAD54L2 RAD54-like 2 (S. cerevisiae)
RAI2 retinoic acid induced 2
RASGRP1 RAS guanyl releasing protein 1 (calcium and DAG-regulated)
RGS2 regulator of G-protein signaling 2
RHOBTB2 Rho-related BTB domain containing 2
RNF126P1 ring finger protein 126 pseudogene 1
SDC3 syndecan 3
SELL selectin L
SIDT1 SID1 transmembrane family, member 1
SLC12A8 solute carrier family 12, member 8
SOWAHC sosondowah ankyrin repeat domain family member C
ST3GAL5 ST3 beta-galactoside alpha-2,3-sialyltransferase 5
THNSL2 threonine synthase-like 2 (S. cerevisiae)
TNFRSF21 tumor necrosis factor receptor superfamily, member 21
TNS3 tensin 3
TRAIP TRAF interacting protein
TRIM21 tripartite motif containing 21
TRPV1 transient receptor potential cation channel, subfamily V, member 1
UPP1 uridine phosphorylase 1
XDH xanthine dehydrogenase
ZBTB22 zinc finger and BTB domain containing 22
ZFP36L2 ZFP36 ring finger protein-like 2
ZNF34 zinc finger protein 34
ZNF35 zinc finger protein 35
ZNF768 zinc finger protein 768