0317956-0000-3969 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

200 genes differentially expressed following the 0317956-0000-3969 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
AFF1 AF4/FMR2 family, member 1
ANKMY1 ankyrin repeat and MYND domain containing 1
APOC1 apolipoprotein C-I
ARHGEF28 Rho guanine nucleotide exchange factor (GEF) 28
ATG10 autophagy related 10
ATP11A ATPase, class VI, type 11A
BATF3 basic leucine zipper transcription factor, ATF-like 3
BCL2 B-cell CLL/lymphoma 2
BCL2L10 BCL2-like 10 (apoptosis facilitator)
BMP8A bone morphogenetic protein 8a
BTN2A2 butyrophilin, subfamily 2, member A2
BUB1 BUB1 mitotic checkpoint serine/threonine kinase
C19ORF57 chromosome 19 open reading frame 57
C19ORF66 chromosome 19 open reading frame 66
CA9 carbonic anhydrase IX
CADM4 cell adhesion molecule 4
CARD14 caspase recruitment domain family, member 14
CASP10 caspase 10, apoptosis-related cysteine peptidase
CCNG2 cyclin G2
CD8A CD8a molecule
CEP112 centrosomal protein 112kDa
CPN1 carboxypeptidase N, polypeptide 1
CRMP1 collapsin response mediator protein 1
CYP2C9 cytochrome P450, family 2, subfamily C, polypeptide 9
CYP4F12 cytochrome P450, family 4, subfamily F, polypeptide 12
DAB2 Dab, mitogen-responsive phosphoprotein, homolog 2 (Drosophila)
DDX60 DEAD (Asp-Glu-Ala-Asp) box polypeptide 60
DENND6B DENN/MADD domain containing 6B
DFNA5 deafness, autosomal dominant 5
DST dystonin
EPN1 epsin 1
EXOSC2 exosome component 2
GPR63 G protein-coupled receptor 63
GYPB glycophorin B (MNS blood group)
HAS1 hyaluronan synthase 1
HCRP1 hepatocellular carcinoma-related HCRP1
HLA-DOA major histocompatibility complex, class II, DO alpha
HS6ST1 heparan sulfate 6-O-sulfotransferase 1
IDI2-AS1 IDI2 antisense RNA 1
IFI27 interferon, alpha-inducible protein 27
IFIH1 interferon induced with helicase C domain 1
IFIT1 interferon-induced protein with tetratricopeptide repeats 1
IFIT3 interferon-induced protein with tetratricopeptide repeats 3
IGFBP3 insulin-like growth factor binding protein 3
IGKV1D-13 immunoglobulin kappa variable 1D-13
IPW imprinted in Prader-Willi syndrome (non-protein coding)
IRF9 interferon regulatory factor 9
KCNH6 potassium channel, voltage gated eag related subfamily H, member 6
KIAA0040 KIAA0040
KIF25 kinesin family member 25
KITLG KIT ligand
KLK14 kallikrein-related peptidase 14
KRIT1 KRIT1, ankyrin repeat containing
MIER2 mesoderm induction early response 1, family member 2
MLLT4 myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 4
MPP2 membrane protein, palmitoylated 2 (MAGUK p55 subfamily member 2)
MST1R macrophage stimulating 1 receptor
NOS1AP nitric oxide synthase 1 (neuronal) adaptor protein
NOX5 NADPH oxidase, EF-hand calcium binding domain 5
NR6A1 nuclear receptor subfamily 6, group A, member 1
NTRK2 neurotrophic tyrosine kinase, receptor, type 2
NUP88 nucleoporin 88kDa
OAS1 2'-5'-oligoadenylate synthetase 1, 40/46kDa
OSGIN2 oxidative stress induced growth inhibitor family member 2
PAX2 paired box 2
PCDH12 protocadherin 12
PCDHB11 protocadherin beta 11
PCLO piccolo presynaptic cytomatrix protein
PCNXL2 pecanex-like 2 (Drosophila)
PDZD2 PDZ domain containing 2
PKNOX2 PBX/knotted 1 homeobox 2
PLA2G7 phospholipase A2, group VII (platelet-activating factor acetylhydrolase, plasma)
PLCE1 phospholipase C, epsilon 1
PLCH1 phospholipase C, eta 1
PLD1 phospholipase D1, phosphatidylcholine-specific
PNMA3 paraneoplastic Ma antigen 3
POLL polymerase (DNA directed), lambda
POU3F4 POU class 3 homeobox 4
PPARD peroxisome proliferator-activated receptor delta
REC8 REC8 meiotic recombination protein
SARDH sarcosine dehydrogenase
SECTM1 secreted and transmembrane 1
SERPINA1 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1
SERPINA4 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 4
SIRT4 sirtuin 4
SKP2 S-phase kinase-associated protein 2, E3 ubiquitin protein ligase
SLC2A5 solute carrier family 2 (facilitated glucose/fructose transporter), member 5
SLC4A7 solute carrier family 4, sodium bicarbonate cotransporter, member 7
SPRR3 small proline-rich protein 3
SPTA1 spectrin, alpha, erythrocytic 1
SPTBN1 spectrin, beta, non-erythrocytic 1
SSX3 synovial sarcoma, X breakpoint 3
SULF1 sulfatase 1
TEX14 testis expressed 14
TFR2 transferrin receptor 2
TLR8 toll-like receptor 8
TMEM259 transmembrane protein 259
TNFSF10 tumor necrosis factor (ligand) superfamily, member 10
TREM2 triggering receptor expressed on myeloid cells 2
UBR2 ubiquitin protein ligase E3 component n-recognin 2

decreased expression

Symbol Name
ADGRE1 adhesion G protein-coupled receptor E1
AHSP alpha hemoglobin stabilizing protein
ALPK1 alpha-kinase 1
ALS2CL ALS2 C-terminal like
AP1S1 adaptor-related protein complex 1, sigma 1 subunit
ARHGAP4 Rho GTPase activating protein 4
B3GNT3 UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 3
BRINP2 bone morphogenetic protein/retinoic acid inducible neural-specific 2
C10ORF95 chromosome 10 open reading frame 95
C14ORF79 chromosome 14 open reading frame 79
C17ORF53 chromosome 17 open reading frame 53
CALHM2 calcium homeostasis modulator 2
CDK18 cyclin-dependent kinase 18
CDKN2D cyclin-dependent kinase inhibitor 2D (p19, inhibits CDK4)
CEND1 cell cycle exit and neuronal differentiation 1
CIC capicua transcriptional repressor
CILP cartilage intermediate layer protein, nucleotide pyrophosphohydrolase
CORT cortistatin
CPNE7 copine VII
CTGF connective tissue growth factor
CUEDC1 CUE domain containing 1
CYP17A1 cytochrome P450, family 17, subfamily A, polypeptide 1
DAGLA diacylglycerol lipase, alpha
DUSP4 dual specificity phosphatase 4
DUSP5 dual specificity phosphatase 5
EEF2KMT eukaryotic elongation factor 2 lysine methyltransferase
EGR3 early growth response 3
EPHA2 EPH receptor A2
EPHB6 EPH receptor B6
EPPK1 epiplakin 1
FFAR2 free fatty acid receptor 2
FLJ22184
FOSL1 FOS-like antigen 1
FOXC1 forkhead box C1
FOXI1 forkhead box I1
GABRB2 gamma-aminobutyric acid (GABA) A receptor, beta 2
GNG4 guanine nucleotide binding protein (G protein), gamma 4
GPR143 G protein-coupled receptor 143
GPR3 G protein-coupled receptor 3
HIST1H4A histone cluster 1, H4a
HMOX1 heme oxygenase 1
HS3ST3A1 heparan sulfate (glucosamine) 3-O-sulfotransferase 3A1
HYMAI hydatidiform mole associated and imprinted (non-protein coding)
IER5 immediate early response 5
IFI35 interferon-induced protein 35
IL1RAPL2 interleukin 1 receptor accessory protein-like 2
IL4R interleukin 4 receptor
IQSEC2 IQ motif and Sec7 domain 2
KCNMB1 potassium channel subfamily M regulatory beta subunit 1
KCNN1 potassium channel, calcium activated intermediate/small conductance subfamily N alpha, member 1
KRI1 KRI1 homolog (S. cerevisiae)
KRT15 keratin 15, type I
KRT83 keratin 83, type II
LIF leukemia inhibitory factor
MAFF v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog F
MAPK8IP1 mitogen-activated protein kinase 8 interacting protein 1
MCTP1 multiple C2 domains, transmembrane 1
N4BP3 NEDD4 binding protein 3
NDOR1 NADPH dependent diflavin oxidoreductase 1
NOD2 nucleotide-binding oligomerization domain containing 2
NPFFR1 neuropeptide FF receptor 1
NPY4R neuropeptide Y receptor Y4
OR1D2 olfactory receptor, family 1, subfamily D, member 2
OR2F1 olfactory receptor, family 2, subfamily F, member 1 (gene/pseudogene)
OSGIN1 oxidative stress induced growth inhibitor 1
PFKFB3 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3
PIPOX pipecolic acid oxidase
PLA2G4C phospholipase A2, group IVC (cytosolic, calcium-independent)
POPDC3 popeye domain containing 3
PRF1 perforin 1 (pore forming protein)
PSCA prostate stem cell antigen
PTPRM protein tyrosine phosphatase, receptor type, M
RAB36 RAB36, member RAS oncogene family
RAD54L2 RAD54-like 2 (S. cerevisiae)
RASGRP1 RAS guanyl releasing protein 1 (calcium and DAG-regulated)
RGS19 regulator of G-protein signaling 19
RIN1 Ras and Rab interactor 1
RPH3A rabphilin 3A
RUSC2 RUN and SH3 domain containing 2
SCGB2A2 secretoglobin, family 2A, member 2
SETBP1 SET binding protein 1
SGCE sarcoglycan, epsilon
SGCG sarcoglycan, gamma (35kDa dystrophin-associated glycoprotein)
SH3TC1 SH3 domain and tetratricopeptide repeats 1
SIDT1 SID1 transmembrane family, member 1
SIPA1 signal-induced proliferation-associated 1
SKI SKI proto-oncogene
SLC2A9 solute carrier family 2 (facilitated glucose transporter), member 9
SPINK5 serine peptidase inhibitor, Kazal type 5
TAOK1 TAO kinase 1
TAS2R1 taste receptor, type 2, member 1
TEP1 telomerase-associated protein 1
TLR1 toll-like receptor 1
TNS2 tensin 2
TNS3 tensin 3
UPP1 uridine phosphorylase 1
VGF VGF nerve growth factor inducible
VPS9D1 VPS9 domain containing 1
WDR78 WD repeat domain 78
ZDHHC14 zinc finger, DHHC-type containing 14