0min_cross-link_ZAP-70_null vs reconstituted_Jurkat (Human) [19605366] Gene Set

Dataset SILAC Phosphoproteomics Signatures of Differentially Phosphorylated Proteins for Gene Perturbations
Category proteomics
Type gene perturbation
Description gene perturbation identified as [gene perturbation]_[cell line] ([organism]) [[publication PMID]] (SILAC Phosphoproteomics)
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105 proteins differentially phosphorylated following the 0min_cross-link_ZAP-70_null vs reconstituted_Jurkat (Human) [19605366] gene perturbation from the SILAC Phosphoproteomics Signatures of Differentially Phosphorylated Proteins for Gene Perturbations dataset.

increased phosphorylation

Symbol Name
ACBD6 acyl-CoA binding domain containing 6
ACP1 acid phosphatase 1, soluble
ACTA1 actin, alpha 1, skeletal muscle
ACTR10 actin-related protein 10 homolog (S. cerevisiae)
ADA adenosine deaminase
ADAM9 ADAM metallopeptidase domain 9
AHCY adenosylhomocysteinase
ANXA2 annexin A2
ARHGEF2 Rho/Rac guanine nucleotide exchange factor (GEF) 2
ATP1A1 ATPase, Na+/K+ transporting, alpha 1 polypeptide
BMF Bcl2 modifying factor
CALM1 calmodulin 1 (phosphorylase kinase, delta)
CASKIN2 CASK interacting protein 2
CBL Cbl proto-oncogene, E3 ubiquitin protein ligase
CCT8 chaperonin containing TCP1, subunit 8 (theta)
CD247 CD247 molecule
CD3E CD3e molecule, epsilon (CD3-TCR complex)
CD3G CD3g molecule, gamma (CD3-TCR complex)
CD84 CD84 molecule
CGN cingulin
CLTC clathrin, heavy chain (Hc)
CRKL v-crk avian sarcoma virus CT10 oncogene homolog-like
CYFIP1 cytoplasmic FMR1 interacting protein 1
DDX3X DEAD (Asp-Glu-Ala-Asp) box helicase 3, X-linked
DOK1 docking protein 1, 62kDa (downstream of tyrosine kinase 1)
DOK2 docking protein 2, 56kDa
DPYSL2 dihydropyrimidinase-like 2
DYRK1A dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A
DYRK1B dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1B
EEF1A1 eukaryotic translation elongation factor 1 alpha 1
ELP3 elongator acetyltransferase complex subunit 3
ENO2 enolase 2 (gamma, neuronal)
EPHA3 EPH receptor A3
ERBB2IP erbb2 interacting protein
FER fer (fps/fes related) tyrosine kinase
FYB FYN binding protein
FYN FYN proto-oncogene, Src family tyrosine kinase
GAB2 GRB2-associated binding protein 2
GDI2 GDP dissociation inhibitor 2
GOLGA5 golgin A5
GRASP GRP1 (general receptor for phosphoinositides 1)-associated scaffold protein
HGS hepatocyte growth factor-regulated tyrosine kinase substrate
HIST2H2BE histone cluster 2, H2be
HIST4H4 histone cluster 4, H4
HNRNPU heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A)
HSP90AB1 heat shock protein 90kDa alpha (cytosolic), class B member 1
HSPA14 heat shock 70kDa protein 14
ITGB1 integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12)
ITSN2 intersectin 2
KIRREL kin of IRRE like (Drosophila)
LAX1 lymphocyte transmembrane adaptor 1
LCK LCK proto-oncogene, Src family tyrosine kinase
LDHA lactate dehydrogenase A
LDHB lactate dehydrogenase B
LPXN leupaxin
LY9 lymphocyte antigen 9
MSL2 male-specific lethal 2 homolog (Drosophila)
PAG1 phosphoprotein membrane anchor with glycosphingolipid microdomains 1
PARD3 par-3 family cell polarity regulator
PECAM1 platelet/endothelial cell adhesion molecule 1
PGAM1 phosphoglycerate mutase 1 (brain)
PGM1 phosphoglucomutase 1
PHLDB3 pleckstrin homology-like domain, family B, member 3
PI4KA phosphatidylinositol 4-kinase, catalytic, alpha
PIK3AP1 phosphoinositide-3-kinase adaptor protein 1
PKM pyruvate kinase, muscle
PKP4 plakophilin 4
PLCG2 phospholipase C, gamma 2 (phosphatidylinositol-specific)
PTPN11 protein tyrosine phosphatase, non-receptor type 11
PTPRA protein tyrosine phosphatase, receptor type, A
R3HCC1L R3H domain and coiled-coil containing 1-like
RAN RAN, member RAS oncogene family
SDCBP syndecan binding protein (syntenin)
SHC1 SHC (Src homology 2 domain containing) transforming protein 1
SIT1 signaling threshold regulating transmembrane adaptor 1
SLAMF6 SLAM family member 6
SNRNP70 small nuclear ribonucleoprotein 70kDa (U1)
STAM2 signal transducing adaptor molecule (SH3 domain and ITAM motif) 2
STK4 serine/threonine kinase 4
TEC tec protein tyrosine kinase
TMIGD2 transmembrane and immunoglobulin domain containing 2
TRIM25 tripartite motif containing 25
TSG101 tumor susceptibility 101
TUBA4A tubulin, alpha 4a
TUBB tubulin, beta class I
TXNRD1 thioredoxin reductase 1
UBASH3B ubiquitin associated and SH3 domain containing B
WAS Wiskott-Aldrich syndrome
ZAP70 zeta-chain (TCR) associated protein kinase 70kDa
ZDHHC17 zinc finger, DHHC-type containing 17

decreased phosphorylation

Symbol Name
ATP1A3 ATPase, Na+/K+ transporting, alpha 3 polypeptide
BDH1 3-hydroxybutyrate dehydrogenase, type 1
CD3D CD3d molecule, delta (CD3-TCR complex)
CD5 CD5 molecule
CD7 CD7 molecule
CD82 CD82 molecule
EIF3M eukaryotic translation initiation factor 3, subunit M
G6PD glucose-6-phosphate dehydrogenase
ITK IL2-inducible T-cell kinase
LAT linker for activation of T cells
MPZL1 myelin protein zero-like 1
OGN osteoglycin
SKAP1 src kinase associated phosphoprotein 1
WDR1 WD repeat domain 1
ZNF404 zinc finger protein 404